Use of in situ Raman, FBRM, and ATR-FTIR probes for the understanding of the solvent-mediated polymorphic transformation of II-I etiracetam in methanol

Organic Process Research and Development

Volumn 16, Issue 1, 2012, Pages 49-56

  Herman, Christelle ^a   Haut, Benoît ^a   Douieb, Sélim ^a   Larcy, Aurélie ^a   Vermylen, Valérie ^b   Leyssens, Tom ^c  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UCB PHARMA   (Belgium)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ATR FTIR; BATCH CRYSTALLIZATION PROCESS; IN-SITU; LEVETIRACETAM; LIQUID PHASIS; ONLINE ANALYZERS; POLYMORPHIC TRANSFORMATION; RAMAN PROBE; SOLUTE CONCENTRATIONS;

METHANOL; ORGANIC SOLVENTS;

PROBES;

EID: 84856166849     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op200168g     Document Type: Article

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