A new approach for the estimation of the melting enthalpy of metastable crystalline compounds using differential scanning calorimetry: Application to the two crystallographic forms of Etiracetam

Journal of Thermal Analysis and Calorimetry

Volumn 107, Issue 2, 2012, Pages 777-788

  Herman, Christelle ^a   Leyssens, Tom ^b   Vermylen, Valerie ^c   Halloin, Veronique ^a   Haut, Benoit ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c UCB PHARMA   (Belgium)

Author keywords

Differential scanning calorimetry; Enthalpy balance; Etiracetam; Melting enthalpy; Thermodynamic

Indexed keywords

CONVENTIONAL METHODS; CRYSTALLINE COMPOUNDS; DIRECT DETERMINATION; ENDOTHERMIC PEAKS; ENTHALPY BALANCE; ETIRACETAM; INNOVATIVE METHOD; MELTING ENTHALPY; MELTING PEAK; METASTABLE FORM; POLYMORPHIC TRANSITIONS; SOLID-SOLID; STABLE FORM; THERMAL INSTABILITIES;

CRYSTALLINE MATERIALS; DIFFERENTIAL SCANNING CALORIMETRY; ENTHALPY; ESTIMATION; THERMODYNAMICS;

MELTING;

EID: 84863485800     PISSN: 13886150     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10973-011-1555-0     Document Type: Article

References (18)

1. Mangin D, Puel F, Veesler S. Polymorphism in processes of crystallization in solution -A practical review. Org Process Res Dev. 2009;13:1241-53.
2. Veesler S, Ferte N, Costes MS, Czjzek S, Astier J.P. Temperature and pH effect on the polymorphism of Aprotinin (PBTI) in sodium bromide solutions. J Cryst Growth Des. 2004;4(6): 1137-41.
3. Giron D. Thermal analysis and calorimetric methods in the characterisation of polymorphs and solvates. Thermochim Acta. 1995;248:1-59.
4. Boettinger WJ, Kattner UR, Moon KW, Perepezko J.H. DTA and heat-flow DSC measurements of alloy melting and freezing, NIST Recommended Practice Guide. 2006.
5. Kolbe E, Wilson LA, Hartel R. A round robin evaluation of differential scanning calorimetry to measure transition enthalpy and temperatures. J Food Eng. 1999;40:95-9.
6. Riesen R. Thermal Analysis Information for Users METTLER TOLEDO: Choosing the right baseline, User Com 25. 2007.
7. Wunderlich B. Thermal analysis. New York: Academic Press; 1990. p. 277-80.
8. Greco A, Maffezzoli A. Correction of melting peaks of different PE grades accounting for heat transfer in DSC samples. Polym Test. 2008;27(1):61-74.
9. Herman, C; PhD Thesis, Université Libre de Bruxelles, Belgium. 2010. Contribution á l'e'tude de la cristallisation, par refroidissement en cuve agite'e, de substances d'inte'rêt pharmaceutique pré-sentant un polymorphisme cristallin. http://theses.ulb.ac.be/ETD-db/ collection/available/ULBetd-12082009-155716/(2010).
10. Brown M.E. Handbook of thermal analysis and calorimetry. Amsterdam: Elsevier; 1998.
11. Marini A, Bernenni V, Flor G, Massarotti V, Riccardi R. An analysis of the factor affecting the peak shape and the quantitative reliability of a heat flux DSC cell. Thermochim Acta. 1985;95(2): 419-24.
12. Marini A, Berbenni V, Massarotti V, Flor G. On the quantitative reliability on heat flux D.S.C. J Therm Anal Calorim. 1988;33(1): 337-42.
13. Grooff D, Villiers MM, Liebenberg W. Thermal methods for evaluating polymorphic transitions in Nefedipine. Thermochim Acta. 2007;454:33-42.
14. Lara-Ochoa F, Pérez GE, Mijangos-Santiago F. Calorimetric determinations and theoretical calculations of polymorphs of thalidomide. J Mol Struct. 2007;840(1-3):97-106.
15. Herman C, Leyssens T, Vermylen V, Halloin V, Haut B. Towards an accurate and precise determination of the solid-solid transition temperature of enantiotropic systems. J Chem Thermodyn. 2011; 43:677-82.
16. Herman C, Haut B, Halloin V, Vermylen V, Leyssens T. Towards the determination of the solubilities of the two enantiotropicallyrelated crystallographic forms of Etiracetam in methanol. Org Process Res Dev. 2011 (accepted).
17. Burger A, Ramberger R. On the polymorphism of pharmaceutical and other molecular crystals-.I. Theory of thermodynamics rules. Mikrochim Acta. 1979;2:259-71.
18. Drebushchak VA, Drebushchak TN, Chukanov NV, Boldyreva EV. Transitions among five polymorphs of chlorpropamide near the melting point. J Therm Anal Calorim. 2008;93(2):343-51.