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Volumn 37, Issue 1, 2012, Pages 301-302

Phospholipase D as a therapeutic target in brain disorders

Author keywords

[No Author keywords available]

Indexed keywords

BUTANOL; CHOLINE; GAMMA SECRETASE; HALOPEMIDE; NUCLEOPHILE; PHOSPHATIDIC ACID; PHOSPHOLIPASE D; PHOSPHOLIPASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 84856116941     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2011.178     Document Type: Note
Times cited : (19)

References (6)
  • 2
    • 77649315183 scopus 로고    scopus 로고
    • Impaired aIIbB3 integrin activation and Shear-dependent thrombus formation in mice lacking phospholipase D1
    • Elvers M, Stenger D, Hagedorn I, Kleinshnitz C, Braun A, Kuijpers MEJ et al (2010). Impaired aIIbB3 integrin activation and Shear-dependent thrombus formation in mice lacking phospholipase D1. Sci Signaling 3: 1-10.
    • (2010) Sci Signaling , vol.3 , pp. 1-10
    • Elvers, M.1    Stenger, D.2    Hagedorn, I.3    Kleinshnitz, C.4    Braun, A.5    Mej, K.6
  • 3
    • 77956730942 scopus 로고    scopus 로고
    • Design, synthesis and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazasprio[4.5]decan-8-yl)ethylbenzamides: Discovery of an isoform selective small-molecule phospholipase D2 (PLD2) inhibitor
    • Lavieri R, Scott SA, Selvy PE, Brown HA, Lindsley CW (2010). Design, synthesis and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8- triazasprio[4.5]decan-8-yl)ethylbenzamides: discovery of an isoform selective small-molecule phospholipase D2 (PLD2) inhibitor. J Med Chem 53: 6706-6719.
    • (2010) J Med Chem , vol.53 , pp. 6706-6719
    • Lavieri, R.1    Scott, S.A.2    Selvy, P.E.3    Brown, H.A.4    Lindsley, C.W.5
  • 4
    • 78650064098 scopus 로고    scopus 로고
    • Phospholipase D2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits
    • Oliveira TG, Chan RB, Tian H, Laredo M, Shui G, Staniszewski A et al (2010). Phospholipase D2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. J Neuro Sci 30: 16419-16428.
    • (2010) J Neuro Sci , vol.30 , pp. 16419-16428
    • Oliveira, T.G.1    Chan, R.B.2    Tian, H.3    Laredo, M.4    Shui, G.5    Staniszewski, A.6
  • 5
    • 77953243856 scopus 로고    scopus 로고
    • Phospholipase D in brain function and Alzheimer's disease
    • Oliveira TG, Di Paolo G (2010). Phospholipase D in brain function and Alzheimer's disease. Biochim Et Biophys Acta 1801: 799-805.
    • (2010) Biochim et Biophys Acta , vol.1801 , pp. 799-805
    • Oliveira, T.G.1    Di Paolo, G.2
  • 6
    • 58249115241 scopus 로고    scopus 로고
    • Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness
    • Scott SA, Selvy PE, Buck J, Cho HP, Criswell TL, Thomas AL et al (2009). Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nat Chem Bio 5: 108-117.
    • (2009) Nat Chem Bio , vol.5 , pp. 108-117
    • Scott, S.A.1    Selvy, P.E.2    Buck, J.3    Cho, H.P.4    Criswell, T.L.5    Thomas, A.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.