Expression of the anti-apoptotic protein BAG3 in human melanomas

Journal of Investigative Dermatology

Volumn 132, Issue 1, 2012, Pages 252-254

  Franco, Renato ^a   Scognamiglio, Giosuè ^a   Salerno, Vincenzo ^b   Sebastiani, Adolfo ^b   Cennamo, Giovanni ^c   Ascierto, Paolo A ^a   Botti, Gerardo ^a   Turco, Maria C ^d   Rosati, Alessandra ^d  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d UNIVERSITY OF SALERNO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; PROTEIN BAG3; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; CANCER GROWTH; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LETTER; LYMPH NODE METASTASIS; MALE; MELANOMA; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TISSUE MICROARRAY; TUMOR GROWTH;

EID: 84856093698     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.257     Document Type: Letter

References (8)

1. Ammirante M, Rosati A, Arra C et al. (2010) IKK-gamma protein is a target of BAG3 regulatory activity in human tumor growth. Proc Natl Acad Sci USA 107:7497-502
2. Casula M, Colombino M, Satta MP et al. (2004) BRAF gene is somatically mutated but does not make a major contribution to malignant melanoma susceptibility: the Italian Melanoma Intergroup Study. J Clin Oncol 22:286-92 (Pubitemid 41095093)
3. Gould Rothberg BE, Rimm DL (2010) Biomarkers: the useful and the not so useful-an assessment of molecular prognostic markers for cutaneous melanoma. J Invest Dermatol 130:1971-87
4. Hu DN (2005) Photobiology of ocular melanocytes and melanoma. Photochem Photobiol 81:506-9
5. Iwasaki M, Homma S, Hishiya A et al. (2007) BAG3 regulates motility and adhesion of epithelial cancer cells. Cancer Res 67: 10252-9 (Pubitemid 350070798)
6. Kassis JN, Virador VM, Guancial EA et al. (2009) Genomic and phenotypic analysis reveals a key role for CCN1 (CYR61) in BAG3-modulated adhesion and invasion. J Pathol 218: 495-504
7. Rosati A, Ammirante M, Gentilella A et al. (2007) Apoptosis inhibition in cancer cells: a novel molecular pathway that involves BAG3 protein. Int J Biochem Cell Biol 39:1337-42 (Pubitemid 47031037)
8. Smalley KS (2010) Understanding melanoma signaling networks as the basis for molecular targeted therapy. J Invest Dermatol 130:28-37