Signaling: An oxysterol ligand for Smoothened

Nature Chemical Biology

Volumn 8, Issue 2, 2012, Pages 139-140

  Sharpe, Hayley J ^a   De Sauvage, Frederic J ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

20 (S) HYDROXYCHOLESTEROL; CYCLOPAMINE; G PROTEIN COUPLED RECEPTOR; OXYSTEROL; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

BINDING SITE; CELL FUNCTION; LIGAND BINDING; NOTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; STEREOCHEMISTRY;

EID: 84856089402     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.774     Document Type: Note

References (9)

1. Hannedouche, S. et al. Nature 475, 524-527 (2011).
2. Liu, C. et al. Nature 475, 519-523 (2011).
3. Nachtergaele, S. et al. Nat. Chem. Biol. 8, 211-220(2012).
4. Chen, J.K., Taipale, J., Young, K.E., Maiti, T. & Beachy, P.A. Proc. Natl. Acad. Sci. USA 99, 14071-14076 (2002).
5. Corcoran, R.B. & Scott, M.P. Proc. Natl. Acad. Sci. USA 103, 8408-8413 (2006).
6. Strutt, H. et al. Curr. Biol. 11, 608-613 (2001).
7. Rominger, C.M. et al. J. Pharmacol. Exp. Ther. 329, 995-1005 (2009).
8. Bazan, J.F. & de Sauvage, F.J. Cell 138, 1055-1056 (2009).
9. Tao, H. et al. Chem. Biol. 18, 432-437 (2011).