-
1
-
-
0027475309
-
The multidrug resistance (mdr1) gene product functions as an ATP channel
-
DOI 10.1073/pnas.90.1.312
-
Abraham EH, Prat AG, Gerweck L, Seneveratne T, Arceci RJ, Kramer R, Guidotti G, and Cantiello HF (1993) The multidrug resistance (mdr1) gene product functions as an ATP channel. Proc Natl Acad Sci USA 90:312-316. (Pubitemid 23010300)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.1
, pp. 312-316
-
-
Abraham, E.H.1
Prat, A.G.2
Gerweck, L.3
Seneveratne, T.4
Arceci, R.J.5
Kramer, R.6
Guidotti, G.7
Cantiello, H.F.8
-
2
-
-
0032479343
-
2-adrenoceptor signaling
-
DOI 10.1016/S0014-5793(98)00664-4, PII S0014579398006644
-
Akerman KE, Näsman J, Lund PE, Shariatmadari R, and Kukkonen JP (1998) Endogenous extracellular purine nucleotides redirect α2- adrenoceptor signaling. FEBS Lett 430:209-212. (Pubitemid 28337914)
-
(1998)
FEBS Letters
, vol.430
, Issue.3
, pp. 209-212
-
-
Akerman, K.E.O.1
Nasman, J.2
Lund, P.-E.3
Shariatmadari, R.4
Kukkonen, J.P.5
-
3
-
-
36549040859
-
The selectivity of protein kinase inhibitors: A further update
-
Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, McLauchlan H, Klevernic I, Arthur JS, Alessi DR, and Cohen P (2007) The selectivity of protein kinase inhibitors: a further update. Biochem J 408:297-315.
-
(2007)
Biochem J
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
McLauchlan, H.6
Klevernic, I.7
Arthur, J.S.8
Alessi, D.R.9
Cohen, P.10
-
4
-
-
0029887199
-
Alkaloid ≲δλτα∀ agonist BW373U86 increases hypoxic tolerance
-
DOI 10.1097/00000539-199606000-00023
-
Bofetiado DM, Mayfield KP, and D'Alecy LG (1996) Alkaloid ≲δλτα∀ agonist BW373U86 increases hypoxic tolerance. Anesth Analg 82:1237-1241. (Pubitemid 26158007)
-
(1996)
Anesthesia and Analgesia
, vol.82
, Issue.6
, pp. 1237-1241
-
-
Bofetiado, D.M.1
Mayfield, K.P.2
D'Alecy, L.G.3
-
5
-
-
33644607461
-
Pathophysiology and therapeutic potential of purinergic signaling
-
Burnstock G (2006) Pathophysiology and therapeutic potential of purinergic signaling. Pharmacol Rev 58:58-86.
-
(2006)
Pharmacol Rev
, vol.58
, pp. 58-86
-
-
Burnstock, G.1
-
6
-
-
0029671036
-
δ- and μ-Opioid receptor mobilization of intracellular calcium in SH-SY5Y human neuroblastoma cells
-
Connor M and Henderson G (1996) δ- and μ-Opioid receptor mobilization of intracellular calcium in SH-SY5Y human neuroblastoma cells. Br J Pharmacol 117: 333-340.
-
(1996)
Br J Pharmacol
, vol.117
, pp. 333-340
-
-
Connor, M.1
Henderson, G.2
-
7
-
-
0035652551
-
Delta opioid receptors mediate glucose uptake in skeletal muscles of lean and obese-diabetic (ob/ob) mice
-
DOI 10.1053/meta.2001.28158
-
Evans AA, Tunnicliffe G, Knights P, Bailey CJ, and Smith ME (2001) Delta opioid receptors mediate glucose uptake in skeletal muscle of lean and obese-diabetic (ob/ob) mice. Metabolism 50:1402-1408. (Pubitemid 34007408)
-
(2001)
Metabolism: Clinical and Experimental
, vol.50
, Issue.12
, pp. 1402-1408
-
-
Evans, A.A.L.1
Tunnicliffe, G.2
Knights, P.3
Bailey, C.J.4
Smith, M.E.5
-
8
-
-
0032750456
-
Opioids and food intake: Distributed functional neural pathways?
-
DOI 10.1054/npep.1999.0050
-
Glass MJ, Billington CJ, and Levine AS (1999) Opioids and food intake: distributed functional neural pathways? Neuropeptides 33:360-368. (Pubitemid 29530128)
-
(1999)
Neuropeptides
, vol.33
, Issue.5
, pp. 360-368
-
-
Glass, M.J.1
Billington, C.J.2
Levine, A.S.3
-
9
-
-
0035542970
-
AMP-activated protein kinase: The energy charge hypothesis revisited
-
Hardie DG and Hawley SA (2001) AMP-activated protein kinase: the energy charge hypothesis revisited. BioEssays 23:1112-1119.
-
(2001)
BioEssays
, vol.23
, pp. 1112-1119
-
-
Hardie, D.G.1
Hawley, S.A.2
-
10
-
-
0030762437
-
The potential for isoenzyme-selective modulation of protein kinase C
-
Hofmann J (1997) The potential for isoenzyme-selective modulation of protein kinase C. FASEB J 11:649-669.
-
(1997)
FASEB J
, vol.11
, pp. 649-669
-
-
Hofmann, J.1
-
11
-
-
33845972272
-
Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP
-
DOI 10.1074/jbc.M606676200
-
Hurley RL, Barré LK, Wood SD, Anderson KA, Kemp BE, Means AR, and Witters LA (2006) Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP. J Biol Chem 281:36662-36672. (Pubitemid 46042133)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.48
, pp. 36662-36672
-
-
Hurley, R.L.1
Barre, L.K.2
Wood, S.D.3
Anderson, K.A.4
Kemp, B.E.5
Means, A.R.6
Witters, L.A.7
-
12
-
-
27744502778
-
β-Adrenoceptors, but not alpha-adrenoceptors, stimulate AMP-activated protein kinase in brown adipocytes independently of uncoupling protein-1
-
DOI 10.1007/s00125-005-1936-7
-
Hutchinson DS, Chernogubova E, Dallner OS, Cannon B, and Bengtsson T (2005) β-Adrenoceptors, but not α-adrenoceptors, stimulate AMP-activated protein kinase in brown adipocytes independently of uncoupling protein-1. Diabetologia 48:2386-2395. (Pubitemid 41618931)
-
(2005)
Diabetologia
, vol.48
, Issue.11
, pp. 2386-2395
-
-
Hutchinson, D.S.1
Chernogubova, E.2
Dallner, O.S.3
Cannon, B.4
Bengtsson, T.5
-
13
-
-
50549100488
-
Regulation of AMP-activated protein kinase activity by G-protein coupled receptors: Potential utility in treatment of diabetes and heart disease
-
Hutchinson DS, Summers RJ, and Bengtsson T (2008) Regulation of AMP-activated protein kinase activity by G-protein coupled receptors: potential utility in treatment of diabetes and heart disease. Pharmacol Ther 119:291-310.
-
(2008)
Pharmacol Ther
, vol.119
, pp. 291-310
-
-
Hutchinson, D.S.1
Summers, R.J.2
Bengtsson, T.3
-
14
-
-
0035861644
-
5′-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside
-
Jakobsen SN, Hardie DG, Morrice N, and Tornqvist HE (2001) 5′-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside. J Biol Chem 276:46912-46916
-
(2001)
J Biol Chem
, vol.276
, pp. 46912-46916
-
-
Jakobsen, S.N.1
Hardie, D.G.2
Morrice, N.3
Tornqvist, H.E.4
-
15
-
-
20844451123
-
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
-
DOI 10.1016/j.cmet.2004.12.003, PII S1550413104000099
-
Kahn BB, Alquier T, Carling D, and Hardie DG (2005) AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 1:15-25. (Pubitemid 43960587)
-
(2005)
Cell Metabolism
, vol.1
, Issue.1
, pp. 15-25
-
-
Kahn, B.B.1
Alquier, T.2
Carling, D.3
Hardie, D.G.4
-
16
-
-
0034675354
-
AMP-activated protein kinase is activated by the stimulations of Gq-coupled receptors
-
Kishi K, Yuasa T, Minami A, Yamada M, Hagi A, Hayashi H, Kemp BE, Witters LA, and Ebina Y (2000) AMP-activated protein kinase is activated by the stimulations of Gq-coupled receptors. Biochem Biophys Res Commun 276:16-22.
-
(2000)
Biochem Biophys Res Commun
, vol.276
, pp. 16-22
-
-
Kishi, K.1
Yuasa, T.2
Minami, A.3
Yamada, M.4
Hagi, A.5
Hayashi, H.6
Kemp, B.E.7
Witters, L.A.8
Ebina, Y.9
-
18
-
-
0029947711
-
Regulation by cAMP-dependent protein kinease of a G-protein-mediated phospholipase C
-
DOI 10.1038/382083a0
-
Liu M and Simon MI (1996) Regulation by cAMP-dependent protein kinease of a G-protein-mediated phospholipase C. Nature 382:83-87. (Pubitemid 26243363)
-
(1996)
Nature
, vol.382
, Issue.6586
, pp. 83-87
-
-
Liu, M.1
Simon, M.I.2
-
19
-
-
2142695757
-
Pharmacological and Signaling Properties of Endogenous P2Y1 Receptors in Cystic Fibrosis Transmembrane Conductance Regulator-Expressing Chinese Hamster Ovary Cells
-
DOI 10.1124/jpet.103.063396
-
Marcet B, Chappe V, Delmas P, and Verrier B (2004) Pharmacological and signaling properties of endogenous P2Y1 receptors in cystic fibrosis transmembrane conductance regulator-expressing Chinese hamster ovary cells. J Pharmacol Exp Ther 309:533-539. (Pubitemid 38542604)
-
(2004)
Journal of Pharmacology and Experimental Therapeutics
, vol.309
, Issue.2
, pp. 533-539
-
-
Marcet, B.1
Chappe, V.2
Delmas, P.3
Verrier, B.4
-
20
-
-
77952291363
-
The M3-muscarinic acetylcholine receptor stimulates glucose uptake in L6 skeletal muscle by a CaMKK-AMPK-dependent mechanism
-
Merlin J, Evans BA, Csikasz RI, Bengtsson T, Summers RJ, and Hutchinson DS (2010) The M3-muscarinic acetylcholine receptor stimulates glucose uptake in L6 skeletal muscle by a CaMKK-AMPK-dependent mechanism. Cell Signal 22:1104-1113.
-
(2010)
Cell Signal
, vol.22
, pp. 1104-1113
-
-
Merlin, J.1
Evans, B.A.2
Csikasz, R.I.3
Bengtsson, T.4
Summers, R.J.5
Hutchinson, D.S.6
-
21
-
-
33748747706
-
Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro
-
DOI 10.1074/jbc.M604399200
-
Momcilovic M, Hong SP, and Carlson M (2006) Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro. J Biol Chem 281:25336-25343. (Pubitemid 44401921)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.35
, pp. 25336-25343
-
-
Momcilovic, M.1
Hong, S.-P.2
Carlson, M.3
-
22
-
-
0037903145
-
A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase
-
DOI 10.1074/jbc.M207453200
-
Ninomiya-Tsuji J, Kajino T, Ono K, Ohtomo T, Matsumoto M, Shiina M, Mihara M, Tsuchiya M, and Matsumoto K (2003) A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase. J Biol Chem 278:18485-18490. (Pubitemid 36799472)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.20
, pp. 18485-18490
-
-
Ninomiya-Tsuji, J.1
Kajino, T.2
Ono, K.3
Ohtomo, T.4
Matsumoto, M.5
Shiina, M.6
Mihara, M.7
Tsuchiya, M.8
Matsumoto, K.9
-
23
-
-
79959338922
-
AMPK is a direct adenylate charge-regulated protein kinase
-
Oakhill JS, Steel R, Chen ZP, Scott JW, Ling N, Tam S, and Kemp BE (2011) AMPK is a direct adenylate charge-regulated protein kinase. Science 332:1433-1435.
-
(2011)
Science
, vol.332
, pp. 1433-1435
-
-
Oakhill, J.S.1
Steel, R.2
Chen, Z.P.3
Scott, J.W.4
Ling, N.5
Tam, S.6
Kemp, B.E.7
-
24
-
-
79955878323
-
δ-Opioid receptors stimulate GLUT1- Mediated glucose uptake through Src- and IGF-1 receptor-dependent activation of PI3-kinase signalling in CHO cells
-
Olianas MC, Dedoni S, and Onali P (2011) δ-Opioid receptors stimulate GLUT1- mediated glucose uptake through Src- and IGF-1 receptor-dependent activation of PI3-kinase signalling in CHO cells. Br J Pharmacol 163:624-637.
-
(2011)
Br J Pharmacol
, vol.163
, pp. 624-637
-
-
Olianas, M.C.1
Dedoni, S.2
Onali, P.3
-
25
-
-
0032866115
-
The ≲δλτα∀-opioid receptor: Molecular pharmacology, signal transduction, and the determination of drug efficacy
-
Quock RM, Burkey TH, Varga E, Hosohata Y, Hosohata K, Cowell SM, Slate CA, Ehlert FJ, Roeske WR, and Yamamura HI (1999) The ≲δλτ α∀-opioid receptor: molecular pharmacology, signal transduction, and the determination of drug efficacy. Pharmacol Rev 51:503-532. (Pubitemid 29420213)
-
(1999)
Pharmacological Reviews
, vol.51
, Issue.3
, pp. 503-532
-
-
Quock, R.M.1
Burkey, T.H.2
Varga, E.3
Hosohata, Y.4
Hosohata, K.5
Cowell, S.M.6
Slate, C.A.7
Ehlert, F.J.8
Roeske, W.R.9
Yamamura, H.I.10
-
26
-
-
0036185520
-
Effects of chronic drug treatments on increases in intracellular calcium mediated by nicotinic acetylcholine receptors in SH-SY5Y cells
-
Ridley DL, Pakkanen J, and Wonnacott S (2002) Effects of chronic drug treatments on increases in intracellular calcium mediated by nicotinic acetylcholine receptors in SH-SY5Y cells. Br J Pharmacol 135:1051-1059. (Pubitemid 34214465)
-
(2002)
British Journal of Pharmacology
, vol.135
, Issue.4
, pp. 1051-1059
-
-
Ridley, D.L.1
Pakkanen, J.2
Wonnacott, S.3
-
27
-
-
64349115078
-
AMPK in the brain: Its roles in energy balance and neuroprotection
-
Ronnett GV, Ramamurthy S, Kleman AM, Landree LE, and Aja S (2009) AMPK in the brain: its roles in energy balance and neuroprotection. J Neurochem 109: 17-23.
-
(2009)
J Neurochem
, vol.109
, pp. 17-23
-
-
Ronnett, G.V.1
Ramamurthy, S.2
Kleman, A.M.3
Landree, L.E.4
Aja, S.5
-
28
-
-
0023942495
-
A mechanistic and kinetic analysis of the interactions of the diastereoisomers of adenosine 3′,5′-(cyclic)phosphorothioate with purified cyclic AMP-dependent protein kinase
-
Rothermel JD and Parker Botelho LH (1988) A mechanistic and kinetic analysis of the interactions of the diastereoisomers of adenosine 3′,5′-(cyclic)phosphorothioate with purified cyclic AMP-dependent protein kinase. Biochem J 251:757-762.
-
(1988)
Biochem J
, vol.251
, pp. 757-762
-
-
Rothermel, J.D.1
Parker Botelho, L.H.2
-
29
-
-
29744451390
-
ATP release via anion channels
-
DOI 10.1007/s11302-005-1557-0
-
Sabirov RZ and Okada Y (2005) ATP release via anion channels. Purinergic Signal 1:311-328. (Pubitemid 43023766)
-
(2005)
Purinergic Signalling
, vol.1
, Issue.4
, pp. 311-328
-
-
Sabirov, R.Z.1
Okada, Y.2
-
30
-
-
13244272004
-
1 receptors
-
DOI 10.1002/glia.20118
-
Shinozaki Y, Koizumi S, Ishida S, Sawada J, Ohno Y, and Inoue K (2005) Cytoprotection against oxidative stress-induced damage of astrocyte by extracellular ATP via P2Y1 receptors. Glia 49:288-300. (Pubitemid 40188506)
-
(2005)
GLIA
, vol.49
, Issue.2
, pp. 288-300
-
-
Shevozaki, Y.1
Koizumi, S.2
Ishida, S.3
Sawada, J.-I.4
Ohno, Y.5
Inoue, K.6
-
32
-
-
77949459392
-
AMPK exerts dual regulatory effects on the PI3K pathway
-
Tao R, Gong J, Luo X, Zang M, Guo W, Wen R, and Luo Z (2010) AMPK exerts dual regulatory effects on the PI3K pathway. J Mol Signal 5:1.
-
(2010)
J Mol Signal
, vol.5
, pp. 1
-
-
Tao, R.1
Gong, J.2
Luo, X.3
Zang, M.4
Guo, W.5
Wen, R.6
Luo, Z.7
-
33
-
-
4143066901
-
Opioids as modulators of cell death and survival - Unraveling mechanisms and revealing new indications
-
DOI 10.1124/pr.56.3.2
-
Tegeder I and Geisslinger G (2004) Opioids as modulators of cell death and survival-unraveling mechanisms and revealing new indications. Pharmacol Rev 56: 351-369. (Pubitemid 39096595)
-
(2004)
Pharmacological Reviews
, vol.56
, Issue.3
, pp. 351-369
-
-
Tegeder, I.1
Geisslinger, G.2
-
34
-
-
47749103323
-
Muscarinic receptor activation of AMP-activated protein kinase inhibits orexigenic neuropeptide mRNA expression
-
Thornton C, Sardini A, and Carling D (2008) Muscarinic receptor activation of AMP-activated protein kinase inhibits orexigenic neuropeptide mRNA expression. J Biol Chem 283:17116-17122.
-
(2008)
J Biol Chem
, vol.283
, pp. 17116-17122
-
-
Thornton, C.1
Sardini, A.2
Carling, D.3
-
36
-
-
33847080728
-
AMP-activated protein kinase in metabolic control and insulin signaling
-
Towler MC and Hardie DG (2007) AMP-activated protein kinase in metabolic control and insulin signaling. Circ Res 100:328-341.
-
(2007)
Circ Res
, vol.100
, pp. 328-341
-
-
Towler, M.C.1
Hardie, D.G.2
-
37
-
-
0033815967
-
Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase
-
Woods A, Azzout-Marniche D, Foretz M, Stein SC, Lemarchand P, Ferré P, Foufelle F, and Carling D (2000) Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase. Mol Cell Biol 20:6704-6711.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6704-6711
-
-
Woods, A.1
Azzout-Marniche, D.2
Foretz, M.3
Stein, S.C.4
Lemarchand, P.5
Ferré, P.6
Foufelle, F.7
Carling, D.8
-
38
-
-
79954517977
-
Structure of mammalian AMPK and its regulation by ADP
-
Xiao B, Sanders MJ, Underwood E, Heath R, Mayer FV, Carmena D, Jing C, Walker PA, Eccleston JF, Haire LF, et al. (2011) Structure of mammalian AMPK and its regulation by ADP. Nature 472:230-233.
-
(2011)
Nature
, vol.472
, pp. 230-233
-
-
Xiao, B.1
Sanders, M.J.2
Underwood, E.3
Heath, R.4
Mayer, F.V.5
Carmena, D.6
Jing, C.7
Walker, P.A.8
Eccleston, J.F.9
Haire, L.F.10
-
39
-
-
0035103403
-
Coincident signalling between the Gi/Go-coupled ≲δλ τα∀-opioid receptor and the Gq-coupled m3 muscarinic receptor at the level of intracellular free calcium in SH-SY5Y cells
-
DOI 10.1046/j.1471-4159.2001.00185.x
-
Yeo A, Samways DS, Fowler CE, Gunn-Moore F, and Henderson G (2001) Coincident signalling between the Gi/Go-coupled ≲δλτ α∀-opioid receptor and the Gq-coupled m3 muscarinic receptor at the level of intracellular free calcium in SH-SY5Y cells. J Neurochem 76:1688-1700. (Pubitemid 32221109)
-
(2001)
Journal of Neurochemistry
, vol.76
, Issue.6
, pp. 1688-1700
-
-
Yeo, A.1
Samways, D.S.K.2
Fowler, C.E.3
Gunn-Moore, F.4
Henderson, G.5
-
42
-
-
78650981570
-
Purinergic receptor stimulation reduces cytotoxic edema and brain infarcts in mouse induced by photothrombosis by energizing glial mitochondria
-
Zheng W, Watts LT, Holstein DM, Prajapati SI, Keller C, Grass EH, Walter CA, and Lechleiter JD (2010) Purinergic receptor stimulation reduces cytotoxic edema and brain infarcts in mouse induced by photothrombosis by energizing glial mitochondria. PLoS ONE 5:e14401.
-
(2010)
PLoS ONE
, vol.5
-
-
Zheng, W.1
Watts, L.T.2
Holstein, D.M.3
Prajapati, S.I.4
Keller, C.5
Grass, E.H.6
Walter, C.A.7
Lechleiter, J.D.8
|