Low antioxidant status of serum uric acid, bilirubin and albumin in patients with neuromyelitis optica

European Journal of Neurology

Volumn 19, Issue 2, 2012, Pages 277-283

  Peng, F ^a   Yang, Y ^a   Liu, J ^a   Jiang, Y ^a   Zhu, C ^a   Deng, X ^a   Hu, X ^a   Chen, X ^a   Zhong, X ^b  

^a THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Albumin; Antioxidant; Bilirubin; Neuromyelitis optica; Uric acid

Indexed keywords

ANTIOXIDANT; BILIRUBIN; SERUM ALBUMIN; URIC ACID;

ADULT; ALBUMIN BLOOD LEVEL; ARTICLE; BILIRUBIN BLOOD LEVEL; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HUMAN; MALE; MULTIPLE SCLEROSIS; MYELOOPTIC NEUROPATHY; PRIORITY JOURNAL; SEX DIFFERENCE; URIC ACID BLOOD LEVEL;

ADULT; BILIRUBIN; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROMYELITIS OPTICA; OXIDATIVE STRESS; SERUM ALBUMIN; URIC ACID;

EID: 84856064453     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2011.03488.x     Document Type: Article

References (38)

1. Ghafourifar P, Mousavizadeh K, Parihar MS, Nazarewicz RR, Parihar A, Zenebe WJ. Mitochondria in multiple sclerosis. Front Biosci 2008; 13: 3116-3126.
2. Toncev G, Milicic B, Toncev S, Samardzic G. Serum uric acid levels in multiple sclerosis patients correlate with activity of disease and blood-brain barrier dysfunction. Eur J Neurol 2002; 9: 221-226.
3. Rentzos M, Nikolaou C, Anagnostouli M, et al. Serum uric acid and multiple sclerosis. Clin Neurol Neurosurg 2006; 108: 527-531.
4. Knapp CM, Constantinescu CS, Tan JH, McLean R, Cherryman GR, Gottlob I. Serum uric acid levels in optic neuritis. Mult Scler 2004; 10: 278-280.
5. Peng F, Zhang B, Zhong X, et al. Serum uric acid levels of patients with multiple sclerosis and other neurological diseases. Mult Scler 2008; 14: 188-196.
6. Mirshafiey A, Mohsenzadegan M. Antioxidant therapy in multiple sclerosis. Immunopharmacol Immunotoxicol 2009; 31: 13-29.
7. Kurien BT, Scofield RH. Autoimmunity and oxidatively modified. Autoimmun Rev 2008; 7: 567-573.
8. Hooper DC, Scott GS, Zborek A, et al. Uric acid, a peroxynitrite scavenger, inhibits CNS inflammation, blood-CNS barrier permeability changes, and tissue damage in a mouse model of multiple sclerosis. FASEB J 2000; 14: 691-698.
9. Ames BN, Cathcart R, Schwiers E, Hochstein P. Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis. Proc Natl Acad Sci U S A 1981; 78: 6858-6862.
10. Stocker RY, Yamamoto AF, McDonagh AN, Glazer AN, Ames BN. Bilirubin is an antioxidant of possible physiological importance. Science 1987; 235: 1043-1046.
11. Di Giuseppe D, Ulivelli M, Bartalini S, et al. Regulation of redox forms of plasma thiols by albumin in multiple sclerosis after fasting and methionine loading test. Amino Acids 2010; 38: 1461-1471.
12. Ihara H, Hashizume N, Hemmi H, Yoshida M. Antioxidant ability of bilirubin, vitamin E, vitamin C, and albumin in the peroxyl-radical-induced hemolysis of human erythrocytes. J Anal Biol Sci 2000; 23: 425-430.
13. Wingerchuk DM, Lennon VA, Pittock SJ, Lucchinetti CF, Weinshenker BG. Revised diagnostic criteria for neuromyelitis optica. Neurology 2006; 66: 1485-1489.
14. McDonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the international panel on the diagnosis of multiple sclerosis. Ann Neurol 2001; 50: 121-127.
15. Mehta PD, Mehta SP. Quantitation of IgG and albumin in CSF and serum from multiple sclerosis patients by enzyme-linked immunosorbent assay. Acta Neurol Scand 1987; 75: 125-129.
16. Liu Y, Li P, Lu J, et al. Bilirubin possesses powerful immunomodulatory activity and suppresses experimental autoimmune encephalomyelitis. J Immunol 2008; 181: 1887-1897.
17. Calabrese V, Lodi R, Tonon C. Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia. J Neurol Sci 2005; 233: 145-162.
18. Pentón-Rol G, Cervantes-Llanos M, Martínez-Sánchez G, et al. TNF-alpha and IL-10 downregulation and marked oxidative stress in Neuromyelitis Optica. J Inflamm (Lond) 2009; 6: 18.
19. Peng F, Zhong X, Deng X, et al. Serum uric acid levels and neuromyelitis optica. J Neurol 2010; 257: 1021-1026.
20. Hooper DC, Spitsin S, Kean RB, et al. Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalo-myelitis and multiple sclerosis. Proc Natl Acad Sci U S A 1998; 95: 675-680.
21. Scott GS, Spitsin SV, Kean RB, Mikheeva T, Koprowski H, Hooper DC. Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors. Proc Natl Acad Sci U S A 2002; 99: 16303-16308.
22. Spitsin S, Hooper DC, Leist T, Streletz LJ, Mikheeva T, Koprowski H. Inactivation of peroxynitrite in multiple sclerosis patients after oral administration of inosine may suggest possible approaches to therapy of the disease. Mult Scler 2001; 7: 313-319.
23. Pauwels EK, Erba PA, Kostkiewicz M. Antioxidants: a tale of two stories. Drug News Perspect 2007; 20: 579-585.
24. Davison A, Tibbits G, Shi ZG, Moon J, et al. Active oxygen in neuromuscular disorders. Mol Cell Biochem 1988; 84: 199-216.
25. Gilgun-Sherki Y, Melamed E, Offen D. The role of oxidative stress in the pathogenesis of multiple sclerosis: the need for effective antioxidant therapy. J Neurol 2004; 251: 261-268.
26. Allameh A, Maleklou N, Zargari M, Sanati MH. The influence of uric acid treatments on liver glutathione system prevent oxidative damages in experimental autoimmune encephalomyelitis mice. Neurosci Lett 2008; 1: 111-115.
27. Wu TW, Carey D, Wu J, Sugiyama H. The cytoprotective effects of bilirubin and biliverdin on rat hepatocytes and human erythrocytes and the impact of albumin. Biochem Cell Biol 1991; 69: 828-834.
28. Chen J, Tu Y, Connolly EC, Ronnett GV. Heme oxygenase-2 protects against glutathione depletion-induced neuronal apoptosis mediated by bilirubin and cyclic GMP. Curr Neurovasc Res 2005; 2: 121-131.
29. Sedlak TW, Saleh M, Higginson DS, Paul BD, Juluri KR, Snyder SH, et al. Bilirubin and glutathione have complementary antioxidant and cytoprotective roles. Proc Natl Acad Sci U S A 2009; 106: 5171-5176.
30. Kirkby KA, Adin CA. Products of heme oxygenase and their potential therapeutic applications. Am J Physiol Renal Physiol 2006; 290: F563-F571.
31. Větvicka V, Miler I, Síma P, Táborský l, Fornůsek L. The effect of bilirubin on the Fc receptor expression and phagocytic activity of mouse peritoneal macrophages. Folia Microbiol 1985; 30: 373-380.
32. Haga Y, Tempero MA, Kay D, Táborský l, Fornůsek L. Intracellular accumulation of unconjugated bilirubin inhibits phytohemagglutinin-induced proliferation and interleukin-2 production of human lymphocytes. Dig Dis Sci 1996; 41: 1468-1474.
33. Takayanagi R, Inoguchi T, Ohnaka K. Clinical and experimental evidence for oxidative stress as an exacerbating factor of diabetes mellitus. J Clin Biochem Nutr 2011; 48: 72-77.
34. Genc S, Genc K, Kumral A, Baskin H, Ozkan H. Bilirubin is cytotoxic to rat oligodendrocytes in vitro. Brain Res 2003; 985: 135-141.
35. Schreibelt G, van Horssen J, van Rossum S, Dijkstra CD, Drukarch B, de Vries HE. Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology. Brain Res Rev 2007; 56: 322-330.
36. Mancuso C, Bates TE, Butterfield DA, et al. Natural antioxidants in Alzheimer's disease. Expert Opin Investig Drugs 2007; 16: 1921-1931.
37. Whitton PS. Inflammation as a causative factor in the aetiology of Parkinson's disease. Br J Pharmacol 2007; 150: 963-976.
38. Drisko JA. The use of antioxidants in transmissible spongiform encephalopathies: a case report. J Am Coll Nutr 2002; 21: 22-25.