Depolarization induces a conformational change in the binding site region of the M 2 muscarinic receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 1, 2012, Pages 285-290

  Dekel, Noa ^a,b   Priest, Michael F ^a   Parnas, Hanna ^b   Parnas, Itzchak ^b   Bezanilla, Francisco ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Acetylcholine; Electrochromic; Fluorescence quenching; Gating

Indexed keywords

ACETYLCHOLINE; FLUORESCENT DYE; G PROTEIN COUPLED RECEPTOR; MUSCARINIC M2 RECEPTOR;

ALLOSTERISM; ARTICLE; BINDING SITE; CONFORMATION; DEPOLARIZATION; FLUORESCENCE; MEMBRANE POTENTIAL; MUTATION; NONHUMAN; PRIORITY JOURNAL;

ALLOSTERIC SITE; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CYSTEINE; FLUORESCENCE; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION; OOCYTES; PERTUSSIS TOXIN; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTOR, MUSCARINIC M2; RHODAMINES; XENOPUS;

EID: 84856011296     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1119424109     Document Type: Article

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