Multidrug-resistant typhoid fever with neurologic findings on the Malawi-Mozambique border

Clinical Infectious Diseases

Volumn 54, Issue 8, 2012, Pages 1100-1106

  Lutterloh, Emily ^a   Likaka, Andrew ^b   Sejvar, James ^c   Manda, Robert ^b   Naiene, Jeremias ^d   Monroe, Stephan S ^c   Khaila, Tadala ^b   Chilima, Benson ^b   Mallewa, MacPherson ^e   Kampondeni, Sam D ^f   Lowther, Sara A ^a   Capewell, Linda ^a,c   Date, Kashmira ^a,c   Townes, David ^a   Redwood, Yanique ^a   Schier, Joshua G ^g   Nygren, Benjamin ^c   Tippett Barr, Beth ^a   Demby, Austin ^a   Phiri, Abel ^b   Lungu, Rudia ^b   Kaphiyo, James ^b   Humphrys, Michael ^c   Talkington, Deborah ^c   Joyce, Kevin ^c   Stockman, Lauren J ^a   Armstrong, Gregory L ^a   Mintz, Eric ^c   more..

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b MINISTRY OF HEALTH   (Malawi)

^c NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

^d Ministerio da Saude   (Mozambique)

^e UNIVERSITY OF MALAWI   (Malawi)

^f QUEEN ELIZABETH CENTRAL HOSPITAL   (Malawi)

^g NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; CHLORAMPHENICOL; COTRIMOXAZOLE; IMMUNOGLOBULIN M ANTIBODY; NALIDIXIC ACID;

ABDOMINAL PAIN; ADOLESCENT; ADULT; AGED; ANTIBIOTIC SENSITIVITY; ARTICLE; ATAXIA; BABINSKI REFLEX; BACTERIUM DETECTION; BACTERIUM ISOLATION; BLOOD ANALYSIS; BLOOD CULTURE; CHILD; CLINICAL ARTICLE; CLONUS; CONFUSION; CONTROLLED STUDY; CONVALESCENCE; DEATH; DISEASE CLASSIFICATION; DISEASE SURVEILLANCE; DYSARTHRIA; EPIDEMIC; FECES ANALYSIS; FEMALE; HEADACHE; HEARING LOSS; HUMAN; HUMAN TISSUE; HYPERREFLEXIA; IMMUNOASSAY; INTERVIEW; LABORATORY TEST; MALAWI; MALE; MEDICAL RECORD REVIEW; MENTAL HEALTH; MINIMUM INHIBITORY CONCENTRATION; MOZAMBIQUE; MULTIDRUG RESISTANCE; NEUROLOGIC EXAMINATION; NEUROMONITORING; NONHUMAN; PARKINSONISM; POPULATION RESEARCH; PRESCHOOL CHILD; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; RURAL AREA; SALMONELLA TYPHI; SCHOOL CHILD; SPASTICITY; TREMOR; TYPHOID FEVER; VERTIGO;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, BACTERIAL; CHILD; CHILD, PRESCHOOL; DISEASE OUTBREAKS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; FEMALE; FEVER; HUMANS; IMMUNOGLOBULIN M; INFANT; MALAWI; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MOLECULAR TYPING; MOZAMBIQUE; NERVOUS SYSTEM DISEASES; SALMONELLA TYPHI; TYPHOID FEVER; YOUNG ADULT;

EID: 84856003590     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cis012     Document Type: Article

References (38)

1. Parry CM, Hien TT, Dougan G, White NJ, Farrar JJ. Typhoid fever. N Engl J Med 2002; 347:1770-82.
2. Crump JA, Luby SP, Mintz ED. The global burden of typhoid fever. Bull World Health Organ 2004; 82:346-53.
3. Archibald LK, McDonald LC, Nwanyanwu O, et al. A hospital-based prevalence survey of bloodstream infections in febrile patients in Malawi: implications for diagnosis and therapy. J Infect Dis 2000; 181:1414-20.
4. Gordon MA, Graham SM, Walsh AL, et al. Epidemics of invasive Salmonella enterica serovar enteritidis and S. enterica serovar Typhimurium infection associated with multidrug resistance among adults and children in Malawi. Clin Infect Dis 2008; 46:963-9.
5. Walsh AL, Phiri AJ, Graham SM, Molyneux EM, Molyneux ME. Bacteremia in febrile Malawian children: clinical and microbiologic features. Pediatr Infect Dis J 2000; 19:312-18.
6. Gordon MA, Walsh AL, Chaponda M, et al. Bacteraemia and mortality among adult medical admissions in Malawi-predominance of non-Typhi salmonellae and Streptococcus pneumoniae. J Infect 2001; 42: 44-9.
7. Sigaúque B, Roca A, Mandomando I, et al. Community-acquired bacteremia among children admitted to a rural hospital in Mozambique. Pediatr Infect Dis J 2009; 28:108-13.
8. Mills-Robertson F, Addy ME, Mensah P, Crupper SS. Molecular characterization of antibiotic resistance in clinical Salmonella Typhi isolated in Ghana. FEMS Microbiol Lett 2002; 215:249-53.
9. Wasfy MO, Frenck R, Ismail TF, Mansour H, Malone JL, Mahoney FJ. Trends of multiple-drug resistance among Salmonella serotype Typhi isolates during a 14-year period in Egypt. Clin Infect Dis 2002; 35: 1265-8.
10. Kariuki S, Revathi G, Muyodi J, et al. Characterization of multidrugresistant typhoid outbreaks in Kenya. J Clin Microbiol 2004; 42: 1477-82.
11. Akinyemi KO, Smith SI, Bola Oyefolu AO, Coker AO. Multidrug resistance in Salmonella enterica serovar Typhi isolated from patients with typhoid fever complications in Lagos, Nigeria. Public Health 2005; 119:321-7.
12. Muyembe-Tamfum JJ, Veyi J, Kaswa M, Lunguya O, Verhaegen J, Boelaert M. An outbreak of peritonitis caused by multidrug-resistant Salmonella Typhi in Kinshasa, Democratic Republic of Congo. Travel Med Infect Dis 2009; 7:40-3.
13. Coovadia YM, Gathiram V, Bhamjee A, et al. An outbreak of multiresistant Salmonella Typhi in South Africa. Q J Med 1992; 82: 91-100.
14. Mandomando I, Sigaú que B, Morais L, et al. Antimicrobial drug resistance trends of bacteremia isolates in a rural hospital in southern Mozambique. Am J Trop Med Hyg 2010; 83:152-7.
15. Feasy NA, Archer BN, Heyderman RS, et al. Typhoid fever and invasive nontyphoid salmonellosis, Malawi and South Africa. Emerg Infect Dis 2010; 16:1448-51.
16. World Health Organization. Manual for the laboratory identification and antimicrobial susceptibility testing of bacterial pathogens of public health importance in the developing world. Available at: http://www.who.int/csr/ resources/publications/drugresist/WHO-CDS-CSR-RMD-2003-6/en/. Accessed 11 February 2011.
17. Ribot E, Fair M, Gautom R, et al. Standardization of pulsed-field gel electrophoresis protocols for the subtyping of Escherichia coli O157:H7, Salmonella, and Shigella for PulseNet. Foodborne Pathog Dis 2006; 3:59-67.
18. Theobald L, Halpin J, Pecic G, et al. Diversity of Salmonella enterica serovar Typhi isolates collected from eastern African countries based on pulsed-field gel electrophoresis and antimicrobial susceptibility testing. Poster presented at the International Conference on Emerging Infectious Diseases (ICEID). Atlanta, Georgia, 2010.
19. Osler W. The principles and practice of medicine. New York: D Appleton and Co, 1892.
20. Osuntokun BO, Bademosi O, Ogunremi K, Wright SG. Neuropsychiatric manifestations of typhoid fever in 959 patients. Arch Neurol 1972; 27:7-13.
21. Khosla SN, Srivastava SC, Gupta S. Neuro-psychiatric manifestations of typhoid. J Trop Med Hyg 1977; 80:95-8.
22. Sawhney IM, Prabhakar S, Dhand UK, Chopra JS. Acute cerebellar ataxia in enteric fever. Trans R Soc Trop Med Hyg 1986; 80:85-6.
23. Ali G, Rashid S, Kamli MA, Shah PA, Allaqaband GQ. Spectrum of neuropsychiatric complications in 791 cases of typhoid fever. Trop Med Int Health 1997; 2:314-18.
24. Parmar RC, Bavdekar SB, Houilgol R, Muranjan MN. Nephritis and cerebellar ataxia: rare presenting features of enteric fever. J Postgrad Med 2000; 46:184-6.
25. van Wolfswinkel ME, Lahri H, Wismans PJ, Petit PL, van Genderen PJ. Early small bowel perforation and cochleovestibular impairment as rare complications of typhoid fever. Travel Med Infect Dis 2009; 7:265-8.
26. Wadia RS, Ichaporia NR, Kiwalkar RS, Amin RB, Sardesai HV. Cerebellar ataxia in enteric fever. J Neurol Neurosur PS 1985; 48:695-7.
27. Thapa R, Banerjee P, Akhtar N, Jain TS. Transient dysautonomia and cerebellitis in childhood enteric fever. J Child Neurol 2008; 23:1081-2.
28. Bhunia R, Hutin Y, Ramakrishnan R, Pal N, Sen T, Murhekar M. A typhoid fever outbreak in a slum of South Dumdum municipality, West Bengal, India, 2007: evidence for foodborne and waterborne transmission. BMC Public Health 2009; 9:115-22.
29. Farooqui A, Khan A, Kazmi SU. Investigation of a community outbreak of typhoid fever associated with drinking water. BMC Public Health 2009; 9:476-81.
30. Aypak A, Cxelik AK, Aypak C, Cxikman Ö . Multidrug resistant typhoid fever outbreak in Ercek village-Van, Eastern Anatolia, Turkey: clinical profile, sensitivity patterns, and response to antimicrobials. Trop Doct 2010; 40:160-2.
31. Olsen SJ, Kafoa B, Win NS, et al. Restaurant-associated outbreak of Salmonella Typhi in Nauru: an epidemiological and cost analysis. Epidemiol Infect 2001; 127:405-12.
32. Neil K, Sodha S, Luswago L, et al. Outbreak of typhoid fever with high rate of intestinal perforations, Kasese District, Uganda-2008-2009. Presented at the 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene. Washington, DC, 2009.
33. Nkemngu NJ, Asonganyi EDN, Njunda AL. Treatment failure in a typhoid patient infected with nalidixic acid resistant S. enterica serovar Typhi with reduced susceptibility to ciprofloxacin: a case report from Cameroon. BMC Infect Dis 2005; 5:49-51.
34. Parry CM, Threlfall EJ. Antimicrobial resistance in typhoidal and nontyphoidal salmonellae. Curr Opin Infect Dis 2008; 21:531-8.
35. Crump J, Kretsinger K, Gay K, et al. Clinical response and outcome of infection with Salmonella enterica serotype Typhi with decreased susceptibility to fluoroquinolones: a United States FoodNet multicenter retrospective cohort study. Antimicrob Agents Chemother 2008; 52:1278-84.
36. Lewis MD, Serichantalergs O, Pitarangsi C, et al. Typhoid fever: a massive, single-point source, multidrug-resistant outbreak in Nepal. Clin Infect Dis 2005; 40:554-61.
37. Mermin JH, Villar R, Carpenter J, et al. A massive epidemic of multidrug-resistant typhoid fever in Tajikistan associated with consumption of municipal water. J Infect Dis 1999; 179:1416-22.
38. World Health Organization. Typhoid vaccines: WHO position paper. Wkly Epidemiol Rec 2008; 83:49-60.