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Volumn 817, Issue , 2012, Pages 69-91

The in vitro mammalian chromosome aberration test

(1)  Clare, Gill a  

a NONE   (United Kingdom)

Author keywords

Accurate test result; Cyclophosphamide; Cytogenetics; Cytotoxicity; Established cell lines; Human lymphocytes; In vitro mammalian chromosome aberration test; Regulatory assay; S 9 mix; Structural chromosome aberrations; Whole blood cultures

Indexed keywords

MAMMALIA;

EID: 84855998622     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-421-6_5     Document Type: Article
Times cited : (28)

References (34)
  • 1
    • 84856011094 scopus 로고    scopus 로고
    • Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment Introduction Department of Health, UK
    • Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment (2000) Guidance on a Strategy for Testing of Chemicals for Mutagenicity. Introduction Department of Health, UK pp 5-7.
    • (2000) Guidance on A Strategy for Testing of Chemicals for Mutagenicity. , pp. 5-7
  • 3
    • 84856013282 scopus 로고    scopus 로고
    • In vitro mammalian cytogenetic test'
    • OECD Genetic Toxicology OECD Paris, Test Guideline
    • OECD (1997) 'Genetic Toxicology: In vitro mammalian Cytogenetic Test'. In OECD Guidelines for the testing of chemicals. OECD Paris, Test Guideline 473.
    • (1997) OECD Guidelines for the Testing of Chemicals , vol.473
  • 6
    • 33846071711 scopus 로고    scopus 로고
    • Determination of genetic toxicity and potential carcinogenicity in vitro - Challenges post the Seventh Amendment to the European Cosmetics Directive
    • DOI 10.1093/mutage/gel052
    • Tweats D.J., Scott A.D., Westmorland C. and Carmichael P.L. (2007) Determination of genetic toxicity and potential carcinogenicity in vitro-challenges post the Seventh Amendment to the European Cosmetics Directive. Mutagenesis 22, 5-13. (Pubitemid 46058637)
    • (2007) Mutagenesis , vol.22 , Issue.1 , pp. 5-13
    • Tweats, D.J.1    Scott, A.D.2    Westmoreland, C.3    Carmichael, P.L.4
  • 7
    • 33847325174 scopus 로고    scopus 로고
    • How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM workshop
    • Kirkland D., Pfuhler S., Tweats D. et al (2007) How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM workshop. Mutat. Res. 628, 31-55.
    • (2007) Mutat. Res. , vol.628 , pp. 31-55
    • Kirkland, D.1    Pfuhler, S.2    Tweats, D.3
  • 8
    • 84965821924 scopus 로고
    • Phytohaemagglutinin: An initiator of mitosis in cultures of normal human leukocytes
    • Nowell, P.C. (1960) Phytohaemagglutinin: an initiator of mitosis in cultures of normal human leukocytes. Cancer Research, 20, 462.
    • (1960) Cancer Research , vol.20 , pp. 462
    • Nowell, P.C.1
  • 9
    • 0016794677 scopus 로고
    • Human peripheral blood lymphocytes for the analysis of chromosome aberrations in muta-gen tests
    • Evans H.J. and O'Riordan M.L. (1975) Human peripheral blood lymphocytes for the analysis of chromosome aberrations in muta-gen tests. Mutation Research, 31, 135.
    • (1975) Mutation Research , vol.31 , pp. 135
    • Evans, H.J.1    O'Riordan, M.L.2
  • 10
    • 0002468690 scopus 로고
    • Human peripheral blood lymphocytes for the analysis of chromosome aberrations Inmutagen tests
    • Kilbey B.J. et al eds Elsevier Science Publishers
    • Evans H.J. (1984) Human peripheral blood lymphocytes for the analysis of chromosome aberrations in mutagen tests. In Handbook of Mutagenicity Test Procedures (Kilbey B.J. et al eds) Elsevier Science Publishers, pp 407-427.
    • (1984) Handbook of Mutagenicity Test Procedures , pp. 407-427
    • Evans, H.J.1
  • 12
    • 84889831448 scopus 로고    scopus 로고
    • Basic principles of cell culture
    • Vunjak-Novakovic G., Freshney R.I. eds.) John Wiley & Sons, Inc.
    • Freshney R.I. (2006). Basic Principles of Cell Culture. In Culture of Cells for Tissue Engineering. (Vunjak-Novakovic G., Freshney R.I. eds.) John Wiley & Sons, Inc., pp 3-22.
    • (2006) Culture of Cells for Tissue Engineering. , pp. 3-22
    • Freshney, R.I.1
  • 13
    • 84856001797 scopus 로고    scopus 로고
    • Corby N (2000) http://www.abdn.ac.uk/safety/uploads/files/blood.doc.
    • (2000)
    • Corby, N.1
  • 14
    • 84856013284 scopus 로고    scopus 로고
    • Advisory Committee on Dangerous Pathogens Protection against blood borne infections in the workplace: HIV and hepatitis
    • ISBN 0113219539
    • Advisory Committee on Dangerous Pathogens Protection against blood borne infections in the workplace: HIV and hepatitis. The Stationery Office, 1996, ISBN 0113219539.
    • (1996) The Stationery Office
  • 15
    • 28044458560 scopus 로고    scopus 로고
    • The yield of radiation-induced chromosomal aberrations in first division human lymphocytes depends on the culture time
    • DOI 10.1080/09553000500303591
    • Hone P., Edwards A., Lloyd D., Moquet J. (2005) The yield of radiation-induced chromosomal aberrations in first division human lymphocytes depends on the culture time. Int J Radiat. Biol. 81, 523-529. (Pubitemid 41687202)
    • (2005) International Journal of Radiation Biology , vol.81 , Issue.7 , pp. 523-529
    • Hone, P.A.1    Edwards, A.A.2    Lloyd, D.C.3    Moquet, J.E.4
  • 16
    • 0017850443 scopus 로고
    • Factors involved in differential Giemsa-Staining of sister chromatids
    • DOI 10.1007/BF00328535
    • Goto K., Maeda S., Kano Y. and Sugiyama T. (1978) Factors involved in differential Giemsa-staining of sister chromatids. Chromosoma (Berl.) 66, 351-359. (Pubitemid 8338046)
    • (1978) Chromosoma , vol.66 , Issue.4 , pp. 351-359
    • Goto, K.1    Maeda, S.2    Kano, Y.3    Sugiyama, T.4
  • 17
    • 0041878604 scopus 로고    scopus 로고
    • Chromosomal aberration frequencies in patients with thalassaemia major undergoing therapy with deferiprone and deferoxamine in a comparative crossover study
    • DOI 10.1093/mutage/geg014
    • Marshall R., Tricta F., Galanello R. et al. (2003) Chromosomal aberration frequencies in patients with thalassaemia major undergoing therapy with deferiprone and deferoxamine in a comparative crossover study. Mutagenesis 18, 457-463. (Pubitemid 37098977)
    • (2003) Mutagenesis , vol.18 , Issue.5 , pp. 457-463
    • Marshall, R.1    Tricta, F.2    Galanello, R.3    Leoni, G.4    Kirkland, D.5    Minto, S.6    Spino, M.7
  • 19
    • 0342766277 scopus 로고
    • An International System for Cytogenetic Nomenclature (Hardnen D.G. and Klinger H.P. eds.) Karger A.G., Basel (Switzerland)
    • An International System for Cytogenetic Nomenclature (1995). Report of the Standing Committee on Human Cytogenetic Nomenclature S. (Hardnen D.G. and Klinger H.P. eds.) Karger A.G., Basel (Switzerland).
    • (1995) Report of the Standing Committee on Human Cytogenetic Nomenclature S.
  • 21
    • 0031831669 scopus 로고    scopus 로고
    • Chromosome aberrations in vitro related to cytotoxicity of nonmutagenic chemicals and metabolic poisons
    • DOI 10.1002/(SICI)1098-2280(1998)31:4<316::AID-EM3>3.0.CO;2-G
    • Hilliard C.A., Armstrong M.J., Bradt C.I., Hill R.B. Greenwood S.K. and Galloway S.M. (1998) Chromosome aberrations in vitro related to cytotoxicity of nonmutagenic chemicals and metabolic poisons. Environ and Mol. Mutagenesis 31, 316-326 (Pubitemid 28308461)
    • (1998) Environmental and Molecular Mutagenesis , vol.31 , Issue.4 , pp. 316-326
    • Hilliard, C.A.1    Armstrong, M.J.2    Bradt, C.I.3    Hill, R.B.4    Greenwood, S.K.5    Galloway, S.M.6
  • 22
    • 34248577471 scopus 로고    scopus 로고
    • Mechanistic influences for mutation induction curves after exposure to DNA-reactive carcinogens
    • DOI 10.1158/0008-5472.CAN-06-4061
    • Doak S.H., Jenkins G.J.S., Johnson G.E. et al (2007) Mechanistic influences for mutation induction curves after exposure to DNA-reactive carcinogens. Cancer Res. 67, 3904-3911. (Pubitemid 46762179)
    • (2007) Cancer Research , vol.67 , Issue.8 , pp. 3904-3911
    • Doak, S.H.1    Jenkins, G.J.S.2    Johnson, G.E.3    Quick, E.4    Parry, E.M.5    Parry, J.M.6
  • 23
    • 0023855146 scopus 로고
    • A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures
    • Ishidate M.Jr., Harnois M.C. and Sofuni T. (1988) A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell culture. Mutat. Res. 195, 151-213. (Pubitemid 18066068)
    • (1988) Mutation Research , vol.195 , Issue.2 , pp. 151-213
    • Ishidate Jr., M.1    Harnois, M.C.2    Sofuni, T.3
  • 27
    • 68049133121 scopus 로고    scopus 로고
    • European Agency for the Evaluation of Medicinal Products R1: Final concept paper: Guidance on genotoxicity testing and data interpretation for pharmaceuticals intended for human use
    • European Agency for the Evaluation of Medicinal Products (2006) ICH Topic S 2 R1: Final concept paper: Guidance on genotoxicity testing and data interpretation for pharmaceuticals intended for human use.
    • (2006) ICH Topic S , vol.2
  • 29
    • 0023010822 scopus 로고
    • Genotoxic effects in cultured mammalian cells produced by low pH treatment conditions and increased ion concentrations
    • DOI 10.1002/em.2860080611
    • Brusick D (1986) Genotoxic effects in cultured mammalian cells produced by low pH treatment conditions and increased ion concentrations. Environ Mutagenesis 8, 879-886. (Pubitemid 17188042)
    • (1986) Environmental Mutagenesis , vol.8 , Issue.6 , pp. 879-886
    • Brusick, D.1
  • 33
    • 0029093718 scopus 로고
    • The effect of PHA stimulation on lymphocyte sub-populations in whole-blood cultures
    • O'Donovan M.R.O., Johns S. and Wilcox P. (1995a) The effect of PHA stimulation on lymphocyte sub-populations in whole-blood cultures. Mutagenesis 10, 371-374.
    • (1995) Mutagenesis , vol.10 , pp. 371-374
    • O'Donovan, M.R.O.1    Johns, S.2    Wilcox, P.3
  • 34
    • 0028980552 scopus 로고
    • Extended cultures of human t-lymphocytes: A practical alternative to primary human lymphocytes for use in genotoxicity testing
    • O'Donovan M.R.O., Freemantle M.R., Hull G. et al (1995b) Extended cultures of human T-lymphocytes: a practical alternative to primary human lymphocytes for use in genotoxicity testing. Mutagenesis 10, 189-201.
    • (1995) Mutagenesis , vol.10 , pp. 189-201
    • O'Donovan, M.R.O.1    Freemantle, M.R.2    Hull, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.