Estradiol directly attenuates sodium currents and depolarizing afterpotentials in isolated gonadotropin-releasing hormone neurons

Brain Research

Volumn 1436, Issue , 2012, Pages 81-91

  Wang, Yong ^a   Kuehl Kovarik, M Cathleen ^b  

^a UNIVERSITY OF MISSOURI   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

Aging; Depolarizing afterpotential; Estradiol; GnRH; Sodium current

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR BETA; GONADORELIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; TETRODOTOXIN;

ACTION POTENTIAL; AFTERDISCHARGE; AGING; ANIMAL CELL; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DEPOLARIZATION; FEEDBACK SYSTEM; FEMALE; GONADORELIN RELEASE; GONADOTROPIN SECRETING CELL; HORMONAL REGULATION; HYPOTHALAMUS; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; REPRODUCTION; SENESCENCE; SODIUM CURRENT;

AGING; ANIMALS; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR BETA; FEMALE; GONADOTROPIN-RELEASING HORMONE; MICE; MICE, TRANSGENIC; NEURONS; NITRILES; OVARIECTOMY; PROPIONATES; SODIUM; SODIUM CHANNELS; TIME FACTORS;

ANIMALIA; MUS;

EID: 84855998021     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.12.013     Document Type: Article

References (33)

1. H. Abe, K.L. Keen, and E. Terasawa Rapid action of estrogens on intracellular calcium oscillations in primate luteinizing hormone-releasing hormone-1 neurons Endocrinology 149 2008 1155 1162 (Pubitemid 351397953)
2. I.M. Abraham, S.K. Han, M.G. Todman, K.S. Korach, and A.E. Herbison Estrogen receptor beta mediates rapid estrogen actions on gonadotropin-releasing hormone neurons in vivo J. Neurosci. 23 2003 5771 5777 (Pubitemid 36807856)
3. B.P. Bean The action potential in mammalian central neurons Nat. Rev. Neurosci. 8 2007 451 465 (Pubitemid 46789230)
4. P.E. Chappell Clocks and the black box: circadian influences on gonadotropin-releasing hormone secretion J. Neuroendocrinol. 17 2005 119 130 (Pubitemid 40425634)
5. Z. Chu, and S.M. Moenter Physiologic regulation of a tetrodotoxin- sensitive sodium influx that mediates a slow after depolarization potential in gonadotropin-releasing hormone neurons: possible implications for the central regulation of fertility J. Neurosci. 26 2006 11961 11973 (Pubitemid 44772107)
6. Z. Chu, J. Andrade, M.A. Shupnik, and S.M. Moenter Differential regulation of gonadotropin-releasing hormone neuron activity and membrane properties by acutely applied estradiol: dependence on dose and estrogen receptor subtype J. Neurosci. 29 2009 5616 5627
7. H.O. de la Iglesia, and W.J. Schwartz Minireview: timely ovulation: circadian regulation of the female hypothalamo-pituitary-gonadal axis Endocrinology 147 2006 1148 1153 (Pubitemid 43244346)
8. M. Fry, A.K. Boegle, and R.A. Maue Differentiated pattern of sodium channel expression in dissociated Purkinje neurons maintained in long-term culture J. Neurochem. 101 2007 737 748 (Pubitemid 46633329)
9. J.E. Hall, H.B. Lavoie, E.E. Marsh, and K.A. Martin Decrease in gonadotropin-releasing hormone (GnRH) pulse frequency with aging in postmenopausal women J. Clin. Endocrinol. Metab. 85 2000 1794 1800 (Pubitemid 32269278)
10. J.R. Hickok, and S.A. Tischkau In vivo circadian rhythms in gonadotropin-releasing hormone neurons Neuroendocrinology 91 2009 110 120
11. E. Hrabovszky, A. Steinhauser, K. Barabas, P.J. Shughrue, S.L. Petersen, I. Merchenthaler, and Z. Liposits Estrogen receptor-beta immunoreactivity in luteinizing hormone-releasing hormone neurons of the rat brain Endocrinology 142 2001 3261 3264 (Pubitemid 32575565)
12. L. Hu, R.L. Gustofson, H. Feng, P.K. Leung, N. Mores, L.Z. Krsmanovic, and K.J. Catt Converse regulatory functions of estrogen receptor-alpha and -beta subtypes expressed in hypothalamic gonadotropin-releasing hormone neurons Mol. Endocrinol. 22 2008 2250 2259
13. M.J. Kelly, and O.K. Ronnekleiv Membrane-initiated estrogen signaling in hypothalamic neurons Mol. Cell. Endocrinol. 290 2008 14 23
14. B.P. Kenealy, K.L. Keen, O.K. Ronnekleiv, and E. Terasawa STX, a novel nonsteroidal estrogenic compound, induces rapid action in primate GnRH neuronal calcium dynamics and peptide release Endocrinology 152 2011 3182 3191
15. T. Kiss Persistent Na-channels: origin and function. A review Acta Biol. Hung 59 Suppl 2008 1 12
16. M.C. Kuehl-Kovarik, W.A. Pouliot, G.L. Halterman, R.J. Handa, F.E. Dudek, and K.M. Partin Episodic bursting activity and response to excitatory amino acids in acutely dissociated gonadotropin-releasing hormone neurons genetically targeted with green fluorescent protein J. Neurosci. 22 2002 2313 2322 (Pubitemid 35386530)
17. M.C. Kuehl-Kovarik, K.M. Partin, R.J. Handa, and F.E. Dudek Spike-dependent depolarizing afterpotentials contribute to endogenous bursting in gonadotropin releasing hormone neurons Neuroscience 134 2005 295 300 (Pubitemid 40943655)
18. S.J. Legan, and H.W. Tsai Oestrogen receptor-alpha and -beta immunoreactivity in gonadotropin-releasing hormone neurones after ovariectomy and chronic exposure to oestradiol J. Neuroendocrinol. 15 2003 1164 1170 (Pubitemid 37540729)
19. S.M. Moenter, Z. Chu, and C.A. Christian Neurobiological mechanisms underlying oestradiol negative and positive feedback regulation of gonadotrophin-releasing hormone neurones J. Neuroendocrinol. 21 2009 327 333
20. S.D. Noel, K.L. Keen, D.I. Baumann, E.J. Filardo, and E. Terasawa Involvement of G-protein coupled receptor 30 (GPR30) in rapid action of estrogen in primate LHRH neurons Mol. Endocrinol. 21 2009 316 321
21. S.L. Petersen, E.N. Ottem, and C.D. Carpenter Direct and indirect regulation of gonadotropin-releasing hormone neurons by estradiol Biol. Reprod. 69 2003 1771 1778 (Pubitemid 37505318)
22. I.M. Raman, and B.P. Bean Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons J. Neurosci. 17 1997 4517 4526 (Pubitemid 27246909)
23. I.M. Raman, and B.P. Bean Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons J. Neurosci. 19 1999 1663 1674 (Pubitemid 29094185)
24. B.S. Rubin Hypothalamic alterations and reproductive aging in female rats: evidence of altered luteinizing hormone-releasing hormone neuronal function Biol. Reprod. 63 2000 968 976
25. J. Sun, Z. Chu, and S.M. Moenter Diurnal in vivo and rapid in vitro effects of estradiol on voltage-gated calcium channels in gonadotropin-releasing hormone neurons J. Neurosci. 30 2010 3912 3923
26. K.J. Suter, W.J. Song, T.L. Sampson, J.P. Wuarin, J.T. Saunders, F.E. Dudek, and S.M. Moenter Genetic targeting of green fluorescent protein to gonadotropin-releasing hormone neurons: characterization of whole-cell electrophysiological properties and morphology Endocrinology 141 2000 412 419 (Pubitemid 32260384)
27. Y. Wang, and M.C. Kuehl-Kovarik Flufenamic acid modulates multiple currents in gonadotropin-releasing hormone neurons Brain Res. 1353 2010 94 105
28. Y. Wang, M. Garro, H.A. Dantzler, J.A. Taylor, D.D. Kline, and M.C. Kuehl-Kovarik Age affects spontaneous activity and depolarizing afterpotentials in isolated gonadotropin-releasing hormone neurons Endocrinology 149 2008 4938 4947
29. Y. Wang, M. Garro, and M.C. Kuehl-Kovarik Estradiol attenuates multiple tetrodotoxin-sensitive sodium currents in isolated gonadotropin-releasing hormone neurons Brain Res. 1345 2010 137 145
30. D.B. Wheeler, A. Randall, and R.W. Tsien Changes in action potential duration alter reliance of excitatory synaptic transmission on multiple types of Ca2 + channels in rat hippocampus J. Neurosci. 16 1996 2226 2237
31. P.M. Wise, M.J. Smith, D.B. Dubal, M.E. Wilson, S.W. Rau, A.B. Cashion, M. Bottner, and K.L. Rosewell Neuroendocrine modulation and repercussions of female reproductive aging Recent Prog. Horm. Res. 57 2002 235 256
32. C. Zhang, M.A. Bosch, E.A. Rick, M.J. Kelly, and O.K. Ronnekleiv 17Beta-estradiol regulation of T-type calcium channels in gonadotropin-releasing hormone neurons J. Neurosci. 29 2009 10552 10562
33. C. Zhang, M.J. Kelly, and O.K. Ronnekleiv 17Beta-estradiol rapidly increases K(ATP) activity in GnRH via a protein kinase signaling pathway Endocrinology 151 2010 4477 4484