Complement fixing donor-specific antibodies and allograft loss

Pediatric Transplantation

Volumn 16, Issue 1, 2012, Pages 1-3

  Jordan, Stanley C ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C1Q ANTIBODY; COMPLEMENT FIXING ANTIBODY; DONOR SPECIFIC ANTIBODY; ECULIZUMAB; IMMUNOGLOBULIN; RITUXIMAB; UNCLASSIFIED DRUG;

ANTIBODY DETECTION; ANTIBODY PRODUCTION; DRUG MEGADOSE; EDITORIAL; HUMAN; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LOW DRUG DOSE; PHENOTYPE;

COMPLEMENT C1Q; FEMALE; GRAFT REJECTION; HUMANS; KIDNEY TRANSPLANTATION; MALE; TRANSPLANTATION, HOMOLOGOUS;

EID: 84855984158     PISSN: 13973142     EISSN: 13993046     Source Type: Journal    
DOI: 10.1111/j.1399-3046.2011.01627.x     Document Type: Editorial

References (11)

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8. Hughes PD, Cohney SJ,. Modifiers of complement activation for prevention of antibody-mediated injury to allografts. Curr Opin Organ Transplant 2011: 16: 425-433.
9. Toyoda M, Pao A, Vo A, et al., Intracellular IFNgamma production in CD3 negative cells exposed to allo-antigens is an indicator of prior sensitization. Transpl Immunol 2010: 22: 121-127.
10. Hidalgo LG, Sis B, Sellares J, et al., NK cell transcripts and NK cells in kidney biopsies from patients with donor-specific antibodies: Evidence for NK cell involvement in antibody-mediated rejection. Am J Transplant 2010: 10: 1812-1822.
11. Chen G, Sequeira F, Tyan DB,. Novel C1q assay reveals a clinically relevant subset of human leukocyte antigen antibodies independent of immunoglobulin G strength on single antigen beads. Hum Immunol 2011: 72: 849-858.