-
1
-
-
0037650078
-
Expression of mutant and wild-type TIMP3 in primary gingival fibroblasts from Sorsby's fundus dystrophy patients
-
DOI 10.1016/S0925-4439(03)00036-X
-
Arris CE, Bevitt DJ, Mohamed J et al (2003) Expression of mutant and wild-type TIMP3 in primary gingival fi broblasts from Sorsby's fundus dystrophy patients. Biochim Biophys Acta 1638: 20-28 (Pubitemid 36577367)
-
(2003)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1638
, Issue.1
, pp. 20-28
-
-
Arris, C.E.1
Bevitt, D.J.2
Mohamed, J.3
Li, Z.4
Langton, K.P.5
Barker, M.D.6
Clarke, M.P.7
McKie, N.8
-
2
-
-
16844386990
-
A novel TIMP3 mutation associated with sorsby fundus dystrophy
-
DOI 10.1001/archopht.123.4.542
-
Barbazetto IA, Hayashi M, Klais CM et al (2005) A novel TIMP3 mutation associated with Sorsby fundus dystrophy. Arch Ophthalmol 123: 542-543 (Pubitemid 40489928)
-
(2005)
Archives of Ophthalmology
, vol.123
, Issue.4
, pp. 542-543
-
-
Barbazetto, I.A.1
Hayashi, M.2
Klais, C.M.3
Yannuzzi, L.A.4
Allikmets, R.5
-
3
-
-
77049113770
-
The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity
-
Brew K, Nagase H (2010) The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity. Biochim Biophys Acta 1803: 55-71
-
(2010)
Biochim Biophys Acta
, vol.1803
, pp. 55-71
-
-
Brew, K.1
Nagase, H.2
-
4
-
-
0024821434
-
Sorsby's fundus dystrophy. A light and electron microscopic study
-
Capon MRC, Marshall J, Krafft JI et al (1989) Sorsby's fundus dystrophy: a light and electron microscopic study. Ophthalmology 96: 1769-1777 (Pubitemid 20013635)
-
(1989)
Ophthalmology
, vol.96
, Issue.12
, pp. 1769-1777
-
-
Capon, M.R.C.1
Marshall, J.2
Krafft, J.I.3
Alexander, R.A.4
Hiscott, P.S.5
Bird, A.C.6
-
5
-
-
77952147434
-
Genetic variants near TIMP3 and high-density lipoprotein-associated loci infl uence susceptibility to age-related macular degeneration
-
Chen W, Stambolian D, Edwards AO et al (2010) Genetic variants near TIMP3 and high-density lipoprotein-associated loci infl uence susceptibility to age-related macular degeneration. Proc Natl Acad Sci USA 107: 7401-7406
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7401-7406
-
-
Chen, W.1
Stambolian, D.2
Edwards, A.O.3
-
6
-
-
0034057990
-
TIMP-3, collagen, and elastin immunohistochemistry and histopathology of Sorsby's fundus dystrophy
-
Chong NH, Alexander RA, Gin T et al (2000) TIMP-3, collagen, and elastin immunohistochemistry and histopathology of Sorsby's fundus dystrophy. Invest Ophthalmol Vis Sci 41: 898-902 (Pubitemid 30158906)
-
(2000)
Investigative Ophthalmology and Visual Science
, vol.41
, Issue.3
, pp. 898-902
-
-
Chong, N.H.V.1
Alexander, R.A.2
Gin, T.3
Bird, A.C.4
Luthert, P.J.5
-
7
-
-
0035677969
-
Clinical features of a novel TIMP-3 mutation causing Sorsby's fundus dystrophy: Implications for disease mechanism
-
DOI 10.1136/bjo.85.12.1429
-
Clarke M, Mitchell KW, Goodship J et al (2001) Clinical features of a novel TIMP-3 mutation causing Sorsby's fundus dystrophy: implications for disease mechanism. Br J Ophthalmol 85: 1429-1431 (Pubitemid 34032907)
-
(2001)
British Journal of Ophthalmology
, vol.85
, Issue.12
, pp. 1429-1431
-
-
Clarke, M.1
Mitchell, K.W.2
Goodship, J.3
McDonnell, S.4
Barker, M.D.5
Griffiths, I.D.6
McKie, N.7
-
8
-
-
80051527752
-
Increased neovascularization in mice lacking tissue inhibitor of metalloproteinases-3
-
Ebrahem Q, Qi J, Sugimoto M et al. (2011) Increased neovascularization in mice lacking tissue inhibitor of metalloproteinases-3. Invest Ophthalmol Vis Sci 52: 6117-6123
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 6117-6123
-
-
Ebrahem, Q.1
Qi, J.2
Sugimoto, M.3
-
9
-
-
0031726862
-
Accumulation of tissue inhibitor of metalloproteinases-3 in human eyes with Sorsby's fundus dystrophy or retinitis pigmentosa
-
Fariss RN, Apte SS, Luthert PJ et al (1998) Accumulation of tissue inhibitor of metalloproteinases- 3 in human eyes with Sorsby's fundus dystrophy or retinitis pigmentosa. Br J Ophthalmol 82: 1329-1334 (Pubitemid 28524133)
-
(1998)
British Journal of Ophthalmology
, vol.82
, Issue.11
, pp. 1329-1334
-
-
Fariss, R.N.1
Apte, S.S.2
Luthert, P.J.3
Bird, A.C.4
Milam, A.H.5
-
10
-
-
6444240024
-
TIMP-3 deficiency leads to dilated cardiomyopathy
-
DOI 10.1161/01.CIR.0000134959.83967.2D
-
Fedak PW, Smookler DS, Kassiri Z et al (2004) TIMP-3 defi ciency leads to dilated cardiomyopathy. Circulation 110: 2401-2409 (Pubitemid 39407346)
-
(2004)
Circulation
, vol.110
, Issue.16
, pp. 2401-2409
-
-
Fedak, P.W.M.1
Smookler, D.S.2
Kassiri, Z.3
Ohno, N.4
Leco, K.J.5
Verma, S.6
Mickle, D.A.G.7
Watson, K.L.8
Hojilla, C.V.9
Cruz, W.10
Weisel, R.D.11
Li, R.-K.12
Khokha, R.13
-
11
-
-
0028879866
-
A novel Ser156Cys mutation in the tissue inhibitor of metalloproteinases-3 (TIMP3) in Sorsby's fundus dystrophy with unusual clinical features
-
Felbor U, Stöhr H, Amann T et al (1995) A novel Ser156Cys mutation in the tissue inhibitor of metalloproteinases-3 (TIMP3) in Sorsby's fundus dystrophy with unusual clinical features. Hum Mol Genet 4: 2415-2416
-
(1995)
Hum Mol Genet
, vol.4
, pp. 2415-2416
-
-
Felbor, U.1
Stöhr, H.2
Amann, T.3
-
12
-
-
0031468856
-
Sorsby fundus dystrophy: Reevaluation of variable expressivity in patients carrying a TIMP3 founder mutation
-
Felbor U, Benkwitz C, Litt M et al (1997) A founder mutation in TIMP3, Ser181Cys, presents with variable expressivity of Sorsby fundus dystrophy. Arch Ophthalmol 115: 1569-1571 (Pubitemid 28007140)
-
(1997)
Archives of Ophthalmology
, vol.115
, Issue.12
, pp. 1569-1571
-
-
Felbor, U.1
Benkwitz, C.2
Klein, M.L.3
Greenberg, J.4
Gregory, C.Y.5
Weber, B.H.F.6
-
13
-
-
45049084310
-
Molecular dissection of TIMP3 mutation S156C associated with Sorsby fundus dystrophy
-
Fogarasi M, Janssen A, Weber BH et al (2008) Molecular dissection of TIMP3 mutation S156C associated with Sorsby fundus dystrophy. Matrix Biol 27: 381-292
-
(2008)
Matrix Biol
, vol.27
, pp. 381-292
-
-
Fogarasi, M.1
Janssen, A.2
Weber, B.H.3
-
14
-
-
34848894584
-
The R345W mutation in EFEMP1 is pathogenic and causes AMD-like deposits in mice
-
DOI 10.1093/hmg/ddm198
-
Fu L, Garland D, Yang Z et al (2007) The R345W mutation in EFEMP1 is pathogenic and causes AMD-like deposits in mice. Hum Mol Genet 16: 2411-2422 (Pubitemid 47500628)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.20
, pp. 2411-2422
-
-
Fu, L.1
Garland, D.2
Yang, Z.3
Shukla, D.4
Rajendran, A.5
Pearson, E.6
Stone, E.M.7
Zhang, K.8
Pierce, E.A.9
-
15
-
-
0029114249
-
Night blindness in Sorsby's fundus dystrophy reversed by vitamin A
-
Jacobson SG, Cideciyan AV, Regunath G et al (1995) Night blindness in Sorsby's fundus dystrophy reversed by vitamin A. Nat Genet 11: 27-32
-
(1995)
Nat Genet
, vol.11
, pp. 27-32
-
-
Jacobson, S.G.1
Cideciyan, A.V.2
Regunath, G.3
-
16
-
-
0036131152
-
Novel mutation in the TIMP3 gene causes Sorsby fundus dystrophy
-
Jacobson SG, Cideciyan AV, Bennett J et al (2002) Novel mutation in the TIMP3 gene causes Sorsby fundus dystrophy. Arch Ophthalmol 120: 376-379 (Pubitemid 34250061)
-
(2002)
Archives of Ophthalmology
, vol.120
, Issue.3
, pp. 376-379
-
-
Jacobson, S.G.1
Cideciyan, A.V.2
Bennett, J.3
Kingsley, R.M.4
Sheffield, V.C.5
Stone, E.M.6
-
17
-
-
48249101519
-
Abnormal vessel formation in the choroid of mice lacking tissue inhibitor of metalloprotease-3
-
Janssen A, Hoellenriegel J, Fogarasi M et al (2008) Abnormal vessel formation in the choroid of mice lacking tissue inhibitor of metalloprotease-3. Invest Ophthalmol Vis Sci 49: 2812-2822
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, pp. 2812-2822
-
-
Janssen, A.1
Hoellenriegel, J.2
Fogarasi, M.3
-
19
-
-
3142714511
-
Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding partner of epithelial growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1): Implications for macular degenerations
-
DOI 10.1074/jbc.M403026200
-
Klenotic PA, Munier FL, Marmorstein LY et al (2004) Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding partner of epithelial growth factor-containing fi bulin-like extracellular matrix protein 1 (EFEMP1). Implications for macular degenerations. J Biol Chem 279: 30469-30473 (Pubitemid 38937976)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.29
, pp. 30469-30473
-
-
Klenotic, P.A.1
Munier, F.L.2
Marmorstein, L.Y.3
Anand-Apte, B.4
-
20
-
-
0034282898
-
A novel tissue inhibitor of metalloproteinases-3 mutation reveals a common molecular phenotype in Sorsby's fundus dystrophy
-
Langton KP, McKie N, Curtis A et al (2000) A novel tissue inhibitor of metalloproteinases-3 mutation reveals a common molecular phenotype in Sorsby's fundus dystrophy. J Biol Chem 275: 27027-27031
-
(2000)
J Biol Chem
, vol.275
, pp. 27027-27031
-
-
Langton, K.P.1
McKie, N.2
Curtis, A.3
-
21
-
-
28744441898
-
Sorsby's fundus dystrophy mutations impair turnover of TIMP-3 by retinal pigment epithelial cells
-
DOI 10.1093/hmg/ddi385
-
Langton KP, McKie N, Smith BM et al (2005) Sorsby's fundus dystrophy mutations impair turnover of TIMP-3 by retinal pigment epithelial cells. Hum Mol Genet 14: 3579-3586 (Pubitemid 41754659)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.23
, pp. 3579-3586
-
-
Langton, K.P.1
McKie, N.2
Smith, B.M.3
Brown, N.J.4
Barker, M.D.5
-
22
-
-
0034833362
-
Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)
-
DOI 10.1172/JCI200112067
-
Leco KJ, Waterhouse P, Sanchez OH et al (2001) Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3). J Clin Invest 108: 817-829 (Pubitemid 32884192)
-
(2001)
Journal of Clinical Investigation
, vol.108
, Issue.6
, pp. 817-829
-
-
Leco, K.J.1
Waterhouse, P.2
Sanchez, O.H.3
Gowing, K.L.M.4
Poole, A.R.5
Wakeham, A.6
Mak, T.W.7
Khokha, R.8
-
23
-
-
33750070028
-
A novel His158Arg mutation in TIMP3 causes a late-onset form of Sorsby fundus dystrophy
-
Lin RJ, Blumenkranz MS, Binkley J et al (2006) A novel His158Arg mutation in TIMP3 causes a late-onset form of Sorsby fundus dystrophy. Am J Ophthalmol 142: 839-848
-
(2006)
Am J Ophthalmol
, vol.142
, pp. 839-848
-
-
Lin, R.J.1
Blumenkranz, M.S.2
Binkley, J.3
-
24
-
-
19544382895
-
Lack of tissue inhibitor of metalloproteinases-3 results in an enhanced inflammatory response in antigen-induced arthritis
-
Mahmoodi M, Sahebjam S, Smookler D et al (2005) Links Lack of tissue inhibitor of metalloproteinases- 3 results in an enhanced infl ammatory response in antigen-induced arthritis. Am J Pathol 166: 1733-1740 (Pubitemid 40734396)
-
(2005)
American Journal of Pathology
, vol.166
, Issue.6
, pp. 1733-1740
-
-
Mahmoodi, M.1
Sahebjam, S.2
Smookler, D.3
Khokha, R.4
Mort, J.S.5
-
25
-
-
4444229437
-
-/- mice leads to chronic hepatic inflammation and failure of liver regeneration
-
DOI 10.1038/ng1413
-
Mohammed FF, Smookler DS, Taylor SE et al (2004) Abnormal TNF activity in Timp3 ?/? mice leads to chronic hepatic infl ammation and failure of liver regeneration. Nat Genet 36: 969-977 (Pubitemid 39167493)
-
(2004)
Nature Genetics
, vol.36
, Issue.9
, pp. 969-977
-
-
Mohammed, F.F.1
Smookler, D.S.2
Taylor, S.E.M.3
Fingleton, B.4
Kassiri, Z.5
Sanchez, O.H.6
English, J.L.7
Matrisian, L.M.8
Au, B.9
Yeh, W.-C.10
Khokha, R.11
-
26
-
-
0024830978
-
Sorsby's fundus dystrophy. A clinical study
-
Polkinghorne PJ, Capon MRC, Berninger T et al (1989) Sorsby's fundus dystrophy: a clinical study. Ophthalmology 96: 1763-1768 (Pubitemid 20013634)
-
(1989)
Ophthalmology
, vol.96
, Issue.12
, pp. 1763-1768
-
-
Polkinghorne, P.J.1
Capon, M.R.C.2
Berninger, T.3
Lyness, A.L.4
Sehmi, K.5
Bird, A.C.6
-
27
-
-
67749133887
-
S156C mutation in tissue inhibitor of metalloproteinases-3 induces increased angiogenesis
-
Qi JH, Dai G, Luthert P et al (2009) S156C mutation in tissue inhibitor of metalloproteinases-3 induces increased angiogenesis. J Biol Chem 284: 19927-19936
-
(2009)
J Biol Chem
, vol.284
, pp. 19927-19936
-
-
Qi, J.H.1
Dai, G.2
Luthert, P.3
-
28
-
-
0037393850
-
A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): Inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2
-
DOI 10.1038/nm846
-
Qi JH, Ebrahem Q, Moore N et al (2003) A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor 2. Nat Med 9: 407-415 (Pubitemid 36460074)
-
(2003)
Nature Medicine
, vol.9
, Issue.4
, pp. 407-415
-
-
Qi, J.H.1
Ebrahem, Q.2
Moore, N.3
Murphy, G.4
Claesson-Welsh, L.5
Bond, M.6
Baker, A.7
Anand-Apte, B.8
-
29
-
-
0037134433
-
Expression of Sorsby's fundus dystrophy mutations in human retinal pigment epithelial cells reduces matrix metalloproteinase inhibition and may promote angiogenesis
-
DOI 10.1074/jbc.M110870200
-
Qi JH, Ebrahem Q, Yeow K et al (2002) Expression of Sorsby's fundus dystrophy mutations in human retinal pigment epithelial cells reduces matrix metalloproteinase inhibition and may promote angiogenesis. J Biol Chem 277: 13394-13400 (Pubitemid 34967932)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.16
, pp. 13394-13400
-
-
Qi, J.H.1
Ebrahem, Q.2
Yeow, K.3
Edwards, D.R.4
Fox, P.L.5
Anand-Apte, B.6
-
30
-
-
67650073274
-
Clinical and biochemical effects of the E139K missense mutation in the TIMP3 gene, associated with Sorsby fundus dystrophy
-
Saihan Z, Li Z, Rice J et al (2009) Clinical and biochemical effects of the E139K missense mutation in the TIMP3 gene, associated with Sorsby fundus dystrophy. Mol Vis 15: 1218-1230
-
(2009)
Mol Vis
, vol.15
, pp. 1218-1230
-
-
Saihan, Z.1
Li, Z.2
Rice, J.3
-
31
-
-
47549086860
-
Clinical course and treatment outcomes of sorsby fundus dystrophy
-
Sivaprasad S. Webster AR, Egan CA et al (2008) Clinical Course and Treatment Outcomes of Sorsby Fundus Dystrophy. Am J Ophthalmol 146: 228-234
-
(2008)
Am J Ophthalmol
, vol.146
, pp. 228-234
-
-
Sivaprasad, S.1
Webster, A.R.2
Egan, C.A.3
-
32
-
-
0141483513
-
S156C affects the morphological and biochemical phenotype but not metalloproteinase homeostasis
-
DOI 10.1002/jcp.10361
-
Soboleva G, Geis B, Schrewe H et al (2003) Sorsby fundus dystrophy mutation Timp3(S156C) affects the morphological and biochemical phenotype but not metalloproteinase homeostasis. J Cell Physiol 197: 149-156 (Pubitemid 37486237)
-
(2003)
Journal of Cellular Physiology
, vol.197
, Issue.1
, pp. 149-156
-
-
Soboleva, G.1
Geis, B.2
Schrewe, H.3
Weber, B.H.F.4
-
33
-
-
0001790180
-
A fundus dystrophy with unusual features (late onset and dominant inheritance of a central retinal lesion showing oedema, haemorrhage and exudates developing into generalised choroidal atrophy with massive pigment proliferation
-
Sorsby A, Mason MEJ, Gardner N (1949) A fundus dystrophy with unusual features (late onset and dominant inheritance of a central retinal lesion showing oedema, haemorrhage and exudates developing into generalised choroidal atrophy with massive pigment proliferation). Br J Ophthalmol 33: 67-97
-
(1949)
Br J Ophthalmol
, vol.33
, pp. 67-97
-
-
Sorsby, A.1
Mej, M.2
Gardner, N.3
-
34
-
-
0031668129
-
A novel splice site mutation in the tissue inhibitor of the metalloprateinases-3 gene in Sorsby's fundus dystrophy with unusual clinical features
-
DOI 10.1007/s004390050803
-
Tabata Y, Isashiki Y, Kamimura K et al (1998) A novel splice site mutation in the tissue inhibitor of the metalloproteinases-3 gene in Sorsby's fundus dystrophy with unusual clinical features. Hum Genet 103: 179-182 (Pubitemid 28444656)
-
(1998)
Human Genetics
, vol.103
, Issue.2
, pp. 179-182
-
-
Tabata, Y.1
Isashiki, Y.2
Kamimura, K.3
Nakao, K.4
Ohba, N.5
-
35
-
-
54049085750
-
Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases
-
Troeberg L, Fushimi K, Khokha R et al (2008) Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases. FASEB J 22: 3515-3524
-
(2008)
FASEB J
, vol.22
, pp. 3515-3524
-
-
Troeberg, L.1
Fushimi, K.2
Khokha, R.3
-
36
-
-
0028097367
-
Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy
-
DOI 10.1038/ng1294-352
-
Weber B, Vogt G, Pruett RC et al (1994) Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy. Nat Genet 8: 352-356 (Pubitemid 24375600)
-
(1994)
Nature Genetics
, vol.8
, Issue.4
, pp. 352-356
-
-
Weber, B.H.F.1
Vogt, G.2
Pruett, R.C.3
Stohr, H.4
Felbor, U.5
-
37
-
-
0036325092
-
A mouse model for sorsby fundus dystrophy
-
Weber BH, Lin B, White K et al (2002) A mouse model for Sorsby fundus dystrophy. Invest Ophthalmol Vis Sci 43: 2732-2740 (Pubitemid 34809467)
-
(2002)
Investigative Ophthalmology and Visual Science
, vol.43
, Issue.8
, pp. 2732-2740
-
-
Weber, B.H.F.1
Lin, B.2
White, K.3
Kohler, K.4
Soboleva, G.5
Herterich, S.6
Seeliger, M.W.7
Jaissle, G.B.8
Grimm, C.9
Reme, C.10
Wenzel, A.11
Asan, E.12
Schrewe, H.13
-
38
-
-
0036154168
-
Sorsby's fundus dystrophy tissue inhibitor of metalloproteinases-3 (TIMP-3) mutants have unimpaired matrix metalloproteinase inhibitory activities, but affect cell adhesion to the extracellular matrix
-
DOI 10.1016/S0945-053X(01)00180-9, PII S0945053X01001809
-
Yeow KM, Kishnani NS, Hutton M et al (2002) Sorsby's fundus dystrophy tissue inhibitor of metalloproteinases-3 (TIMP-3) mutants have unimpaired matrix metalloproteinase inhibitory activities, but affect cell adhesion to the extracellular matrix. Matrix Biol 21: 75-88 (Pubitemid 34100825)
-
(2002)
Matrix Biology
, vol.21
, Issue.1
, pp. 75-88
-
-
Yeow, K.M.1
Kishnani, N.S.2
Hutton, M.3
Hawkes, S.P.4
Murphy, G.5
Edwards, D.R.6
|