Monoclonal antibody 12D5 inhibits eosinophil infiltration in the brain of Angiostrongylus cantonensis-infected BALB/c mice

Acta Tropica

Volumn 121, Issue 2, 2012, Pages 118-124

  Li, Jun Jian ^a,b,c   Zhang, Ren Li ^a   Fu, Yu Cai ^c   Wu, Wei ping ^b   Chen, Mu Xin ^b   Geng, Yi Jie ^a   Huang, Da Na ^a   Ai, Lin ^b   Yang, Fan ^a   Hu, Zhong ^c  

^a SHENZHEN CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^c SHANTOU UNIVERSITY   (China)

Author keywords

12D5; Angiostrongylus cantonensis; Eosinophils; Monoclonal antibody

Indexed keywords

EOTAXIN; INTERLEUKIN 4; INTERLEUKIN 5; MESSENGER RNA; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 12D5; UNCLASSIFIED DRUG;

ANTIBODY; ANTIGEN; BRAIN; INFILTRATION; RODENT;

ANGIOSTRONGYLIASIS; ANGIOSTRONGYLUS CANTONENSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CELL NUCLEUS; CONTROLLED STUDY; DRUG EFFECT; EOSINOPHIL COUNT; EOSINOPHILIC MENINGOENCEPHALITIS; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; MENINGOENCEPHALITIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RNA EXTRACTION; SPLEEN; SURVIVAL RATE;

ANGIOSTRONGYLUS CANTONENSIS; ANIMALS; ANTIBODIES, HELMINTH; ANTIBODIES, MONOCLONAL; BRAIN; CHEMOKINE CCL11; EOSINOPHILS; FEMALE; GENE EXPRESSION PROFILING; IMMUNOLOGIC FACTORS; INJECTIONS, INTRAPERITONEAL; INTERLEUKIN-4; INTERLEUKIN-5; MENINGITIS; MICE; MICE, INBRED BALB C; SPLEEN; STRONGYLIDA INFECTIONS; SURVIVAL ANALYSIS;

ANGIOSTRONGYLUS CANTONENSIS; MUS;

EID: 84855915869     PISSN: 0001706X     EISSN: 18736254     Source Type: Journal    
DOI: 10.1016/j.actatropica.2011.10.013     Document Type: Article

References (42)

1. Abbs A.K. Disorders of the immune system. Robbin's Pathologic Basis of Diseases 2005, 192-264. Saunders, Philadelphia. seventh ed. R.S. Cotran, V. Kumar, T. Collins (Eds.).
2. Barbara P.D., Alberto D.C., Raisa B.C.F., Hermes F.H., Jesús C.B., Consuelo S.M. Intrathecal synthesis of IgE in children with eosinophilic meningoencephalitis caused by Angiostrongylus cantonensis. Cerebrospinal Fluid Res. 2008, 5(1):18.
3. Brode S., Farashi N., Cowburn A.S., Juss J.K., Condiffe A.M., Chilvers E.R. Interleukin-5 inhibits glucocorticoid-mediated apoptosis in human eosinophils. Thorax 2010, 10:1136-1137.
4. Busse W.W., Sedqwick J.B. Eosinophils in asthma. Ann. Allergy 1992, 68:286-290.
5. Capron T.o., Dessaint J.P., Haque To, Capron M. Antibody dependent cell-mediated cytotoxicity against parasites. Prog. Allergy 1982, 31:234-267.
6. Chang E.E., Yen C.M. Eosinophil chemoattracted by eotaxin from cerebrospinal fluid of mice infected with Angiostrongylus cantonensis assayed in a microchamber. Kaohsiung J. Med. Sci. 2004, 20:209-215.
7. Chang E.E., Chung L.Y., Yen C.M. Kinetics of change in the eotaxin concentration in the serum and cerebrospinal fluid of mice infected with Angiostrongylus cantonensis. Parasitol. Res. 2004, 92:137-141.
8. Chen M.X., Zhang R.L., Chen J.X., Chen S.H., Li X.H., Gao S.T., Geng Y.J., Huang D.N., Ai L., Xu M.J., Zhu X.Q. Monoclonal antibodies against excretory/secretory antigens of Angiostrongylus cantonensis. Hybridoma 2010, 29:447-452.
9. Chen Z.C., Rachel S., Julie L., Rick C.L., Zhao H.Y., Dai Z.D., Joanna K.K., Stephen H.L., Robert H.P. Pre- and post-exposure protection against virulent anthrax infection in mice by humanized monoclonal antibodies to Bacillus anthracis capsule. PNAS J. 2010, 108:739-744.
10. Chiu W.C., Lai Y.P., Chou M.Y. Humanization and characterization of an anti-Human TNF-α murine monoclonal antibody. PloS ONE 2011, 6(1):e16373. [Epub ahead of print].
11. Chuang C.C., Su K.E., Chen C.W., Fan C.K., Lin F.K., Chen Y.S., Du W.Y. Anti-CCR3 monoclonal antibody inhibits eosinophil infiltration in Angiostrongylus cantonensis-infected ICR mice. Acta Tropica 2010, 113:209-213.
12. Daugherty B.L., Siciliano S.J., Demartino J.A., Malkowitz L., Sirotina A., Springer M.S. Cloning, expression and characterization of the human eosinophil eotaxin receptor. J. Exp. Med. 1996, 183:2349-2354.
13. Dorta-Contreras A.J., Noris-García E., Bu Coifiú-Fanego R., Padilla-Docal B. Bases moleculares de la Neuroinmunología (II). El reibergrama y su uso en Neuroinmunología. Rev. Cubana. Pediatr. 2005, 77:3-4.
14. Dorta-Contreras A.J., Noris-García E., Escobar-Pérez X., Dueñas-Flores A., Mena-López R. Patrones de síntesis intratecal de subclases de IgG por Angiostrongylus cantonensis. Rev. Neurol. 2003, 36:506-509.
15. Du W.Y., Liao J.W., Fan C.K., Su K.E. Combined treatment with Interleukin-12 and Mebendazole lessens the severity of experimental eosinophilic meningitis caused by Angiostrongylus cantonensis in ICR mice. Infect. Immun. 2003, 71:3947-3953.
16. Greenfeder S., Umland S.P., Cuss F.M., Chapman R.W., Egan R.W. Th2 cytokines and asthma: the role of interleukin-5 in allergic eosinophilic disease. Respir. Res. 2001, 2:71-79.
17. Ichinose M., Barnes P.J. Cytokine-directed therapy in asthma. Curr. Drug Targets 2004, 3:263-269.
18. Intapan P.M., Niwattayakul K., Kittimongkolma S., Sawanyawisuth K., Chotmongkol V., Maleewong W. Cerebrospinal fluid eotaxin and eotaxin-2 levels in human eosinophilic meningitis associated with angiostrongyliasis. Cytokine 2007, 39:138-141.
19. Intapan P.M., Kittimongkolma S., Niwattayakul K., Sawanyawisuth K., Maleewong W. Crebrospinal fluid cytokine responses in human eosinophilic meningitis associated with angiostrongyliasis. J. Neurol. Sci. 2008, 267:17-21.
20. Joyce V., Emiliano C., Stefania B., Maria D.L., Marta B., Paola T., Peter E.S., Thomas J.R., Sergio P., Alessandro D.S. Uterine serous papillary carcinomas over express human trophoblast-cell-surface- marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized anti-Trop-2 monoclonal antibody. Cancer 2011, 117:3163-3172.
21. Joseph M., Aioult C., Capron To., Vorng H., Viens P. A new function of platelets: IgE-dependent killing of schistosomes. Nature 1983, 303:810-812.
22. Kensei T., Michinori O., Yukio K., Toshiki U., Takashi W., Takashi O., Dai M., Tatsuya S., Masakazu M., Masanobu K., Damien C., James E.W., Minori K. Phase I study of LY2469298, an Fc-engineered humanized anti-CD20 antibody, in patients with relapsed or refractory follicular lymphoma. Cancer Sci. 2011, 102:432-438.
23. Kitaura M., Nakajima T., Imai T., Harada S., Combadiere C., Tiffany H.L., Murphy P.M., Yoshie O. Molecular cloning of human eotaxin, an eosinophil-selective CC chemokin, and identification of a specific eosinophil eotaxin receptor, CC chemokin receptor 3. J. Biol. Chem. 1996, 271:7725-7730.
24. Kittimongkolma S., Intapan P.M., Laemviteevanich K., Kanpittaya J., Sawanyawisuth K., Maleewong W. Eosinophilic meningitis associated with angiostrongyliasis: clinical features, laboratory investigations and specific diagnostic IgG and IgG subclass antibodies in cerebrospinal fluid. Southeast Asian J. Trop. Med. Public Health 2007, 38:24-31.
25. Lacy P., Moqbel R. Immune effector functions of eosinophils in allergic airway inflammation. Curr. Opin. Allergy Clin. Immunol. 2001, 1:79-84.
26. Lan K.P., Wang C.J., Hsu J.D., Chen K.M., Lai S.C., Lee H.H. Induced eosinophilia and proliferation in Angiostrongylus cantonensis-infected mouse brain are associated with the induction of JAK/STAT1, IAP/NF-kappaB and MEKK1/JNK signals. J. Helminthol. 2004, 78:311-317.
27. Meeusen E.N.T., Balic A. Do eosinophils have a role in the killing of helminth parasites. Parasitol. Today 2000, 16:95-101.
28. Padilla-Docal B., Dorta-Contreras A.J., Bu-Coifiu-Fanego R. Activación y biosíntesis intratecal de C3c en niños con meningoencefalitis eosinofílica por Angiostrongylus cantonensis. Rev. Neurol. 2009, 48:632-635.
29. Padilla-Docal B., Dorta-Contreras A.J., Bu Coifiu Fanego R., Callol Barroso J. Rol de la lectina de unión a manosa en infecciones parasitarias. Rev. Panam. Infectol. 2009, 11:45-48.
30. Padilla-Docal B., Dorta-Contreras A.J., Bu-Coifiu-Fanego R., Rodríguez-Rey A., Gutiérrez-Hernández J.C., Paula-Almeida S.O. Reibergram of intrathecal synthesis of C4 in patients with eosinophilic meningitis caused by Angiostrongylus cantonensis. Am. J. Trop. Med. Hyg. 2010, 82(6):1094-1098.
31. Perez O., Capron M., Lastre M., Venge P., Khalife J., Capron A. Angiostrongylus cantonensis: role of eosinophils in the neurotoxic syndrome (Gordon-like phenomenon). Exp. Parasitol. 1989, 68:403-413.
32. Ponath P.D., Qin S., Post T.W., Wang J., Wu L., Gerard N.P., Newman W., Gerard C., Mackay C.R. Molecular cloning and characterization of human eotaxin receptor expressed selectively on eosinophils. J. Exp. Med. 1996, 183:2437-2448.
33. Roberto D.P., Makoto I., Midori T. Grafting of abbreviated complementarity determining regions containing specificity determining residues essential for ligand contact to engineer a less immunogenic humanized monoclonal antibody. J. Immunol. 2002, 169:3076-3084.
34. Rothenberg M.E., Luster A.D., Leder P. Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4 induced tumor suppression. Proc. Natl. Acad. Sci. 1995, 92:8960-8964.
35. Shi H.Z. Eosinophils function as antigen-presenting cells. J. Leukoc. Biol. 2004, 76:520-527.
36. Sugaya H., Aoki M., Yoshida T., Takatsu K., Yoshimura K. Eosinophilia and intracranial worm recovery in interleukin-5 transgenic and interleukin-5 receptor alpha chain-knockout mice infected with Angiostrongylus cantonensis. Parasitol. Res. 1997, 83:583-590.
37. Sugaya H., Abe T., Yoshimura K. Eosinophils in the cerebrospinal fluid of mice infected with Angiostrongylus cantonensis are resistant to apoptosis. Int. J. Parasitol. 2001, 31:1649-1658.
38. Tan F., Pan C.W., Liang S.H., Huang H.C. Preparation and preliminary application of monoclonal antibodies against adult worm of Angiostrongylus cantonensis. Chin. J. Parasitol. Parasit. Dis. 2005, 23:209-212.
39. Tatomirovi Z., Bokun R., Bokonji D. Intrathecal synthesis of complement components C3c and C4 in the central nervous system infections with signs of acute serous meningitis syndrome. Vojnosanit Pregl. 2002, 59:265-270.
40. Timothy S.L., Renee S.M., Kim E., Jeffrey T.L., Yu S.F., Julie A.M., Lqbal S.G., Law C.L. Distinct apoptotic signaling characteristics of the anti-CD40 monoclonal antibody dacetuzumab and rituximab produce enhanced antitumor activity in non-Hodgkin lymphoma. Clin. Cancer Res. 2011, 17(14):4672-4681.
41. Tsai H.C., Lee S.S., Huang C.K., Yen C.M., Chen E.R., Liu Y.C. Outbreak of eosinophilic meningitis associated with drinking raw vegetable juice in southern Taiwan. Am. J. Trop. Med. Hyg. 2004, 71:222-226.
42. Wardlaw A.J., Brightiling C., Green R., Woltmann G., Pavord I. Eosinophils in asthma and other allergic diseases. Br. Med. Bull. 2000, 56:985-991.