The medial prefrontal cortex is both necessary and sufficient for the acquisition of conditioned defeat

Neuropharmacology

Volumn 62, Issue 2, 2012, Pages 933-939

  Markham, Chris M ^a   Luckett, Cloe A ^a   Huhman, Kim L ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Aggression; Amygdala; Conditioned fear; Defensive behavior; Social stress

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ANISOMYCIN; BICUCULLINE;

AGGRESSION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASOLATERAL AMYGDALA; BEHAVIOR; CONDITIONED DEFEAT; CONTROLLED STUDY; DEFENSIVE BEHAVIOR; EXPERIMENTAL ANIMAL; HAMSTER; LEARNING; MALE; MEDIAN PREFRONTAL CORTEX; MEMORY CONSOLIDATION; NERVE CELL PLASTICITY; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; SOCIAL STRESS; SUBMISSIVE BEHAVIOR; TERRITORIALITY;

AGGRESSION; ANIMALS; BEHAVIOR, ANIMAL; BICUCULLINE; CRICETINAE; DOMINANCE-SUBORDINATION; FEAR; GABA-A RECEPTOR AGONISTS; GABA-A RECEPTOR ANTAGONISTS; MALE; MESOCRICETUS; MUSCIMOL; PREFRONTAL CORTEX;

EID: 84855915596     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.09.026     Document Type: Article

References (43)

1. I. Akirav, and M. Maroun The role of the medial prefrontal cortex-amygdala circuit in stress effects on the extinction of fear Neural Plast. 2007 2007 30873
2. T.A. Allen, N.S. Narayanan, D.B. Kholodar-Smith, Y. Zhao, M. Laubach, and T.H. Brown Imaging the spread of reversible brain inactivations using fluorescent muscimol J. Neurosci. Methods 171 2008 30 38
3. H.A. al Maskati, and A.W. Zbrozyna Stimulation in prefrontal cortex area inhibits cardiovascular and motor components of the defence reaction in rats J. Auton. Nerv. Syst. 28 1989 117 125
4. S. Blum, A.E. Hebert, and P.K. Dash A role for the prefrontal cortex in recall of recent and remote memories Neuroreport 17 2006 341 344
5. R. Bourtchouladze, T. Abel, N. Berman, R. Gordon, K. Lapidus, and E.R. Kandel Different training procedures recruit either one or two critical periods for contextual memory consolidation, each of which requires protein synthesis and PKA Learn. Mem. 5 1998 365 374
6. J.D. Brioni, A.H. Nagahara, and J.L. McGaugh Involvement of the amygdala GABAergic system in the modulation of memory storage Brain Res. 487 1989 105 112
7. M. Davis Neurobiology of fear responses: the role of the amygdala J. Neuropsychiatry Clin. Neurosci. 9 1997 382 402
8. M. Davis The role of the amygdala in conditioned and unconditioned fear and anxiety J.P. Aggleton, The Amygdala 2000 Oxford University Press New York 213 288
9. D.E. Day, M.A. Cooper, C.M. Markham, and K.L. Huhman NR2B subunit of the NMDA receptor in the basolateral amygdala is necessary for the acquisition of conditioned defeat in Syrian hamsters Behav. Brain Res. 217 2011 55 59
10. N.S. Floyd, J.L. Price, A.T. Ferry, K.A. Keay, and R. Bandler Orbitomedial prefrontal cortical projections to distinct longitudinal columns of the periaqueductal gray in the rat J. Comp. Neurol. 422 2000 556 578
11. N.S. Floyd, J.L. Price, A.T. Ferry, K.A. Keay, and R. Bandler Orbitomedial prefrontal cortical projections to hypothalamus in the rat J. Comp. Neurol. 432 2001 307 328
12. R.J. Frysztak, and E.J. Neafsey The effect of medial frontal cortex lesions on respiration, "freezing", and ultrasonic vocalization during conditioned emotional responses in rats Cereb. Cortex 1 1991 418 425
13. J.C. Gewirtz, W.A. Falls, and M. Davis Normal conditioning inhibition and extinction of freezing and fear-potentiated startle following electrolytic lesions of medial prefrontal cortex in rats Behav. Neurosci. 111 1997 712 726
14. R.R. Holson Mesial prefrontal cortical lesions and timidity in rats 1. Reactivity to aversive stimuli Physiol. Behav. 37 1986 221 230
15. K.L. Huhman, M.B. Solomon, M. Janicki, A.C. Harmon, S.M. Lin, J.E. Israel, and A.M. Jasnow Conditioned defeat in male and female Syrian hamsters Horm. Behav. 44 2003 293 299
16. A receptors in the amygdala blocks the acquisition and expression of conditioned defeat in Syrian hamsters Brain Res. 920 2001 142 150
17. A.M. Jasnow, C. Shi, J.E. Israel, M. Davis, and K.L. Huhman Memory of social defeat is facilitated by cAMP response element-binding protein overexpression in the amygdala Behav. Neurosci. 119 2005 1125 1130
18. J.E. LeDoux Emotion circuits in the brain Ann. Rev. Neurosci. 23 2000 155 184
19. M. Majchrzak, and G. Di Scala GABAA and muscimol as reversible inactivation tools in learning and memory Neural Plast. 7 2000 19 29
20. S. Maren Neurobiology of Pavlovian fear conditioning Annu. Rev. Neurosci. 24 2001 897 931
21. C.M. Markham, and K.L. Huhman Is the medial amygdala part of the neural circuit modulating conditioned defeat in Syrian hamsters? Learn. Mem. 15 2008 6 12
22. C.M. Markham, S.L. Taylor, and K.L. Huhman Role of amygdala and hippocampus in the neural circuit subserving conditioned defeat in Syrian hamsters Learn. Mem. 17 2010 109 116
23. J.H. Martin, and C. Ghez Pharmacological inactivation in the analysis of the central control of movement J. Neurosci. Methods 86 1999 145 159
24. A.J. McDonald, F. Mascagni, and L. Guo Projections of the medial and lateral prefrontal cortices to the amygdala: a Phaseolus vulgaris leucoagglutinin study in the rat Neuroscience 71 1996 55 75
25. M.R. Milad, and G.J. Quirk Neurons in the medial prefrontal cortex signal memory for fear extinction Nature 420 2002 70 74
26. M.R. Milad, I. Vidal-Gonzalez, and G.J. Quirk Electrical stimulation of medial prefrontal cortex reduces conditioned fear in a temporally specific manner Behav. Neurosci. 118 2004 389 394
27. E.M. Mintz, C.F. Gillespie, C.L. Marvel, K.L. Huhman, and H.E. Albers Serotonergic regulation of circadian rhythms in Syrian hamsters Neuroscience 79 1997 563 569
28. M.A. Morgan, L.M. Romanski, and J.E. LeDoux Extinction of emotional learning: contribution of medial prefrontal cortex Neurosci. Lett. 163 1993 109 113
29. M.A. Morgan, and J.E. LeDoux Differential contribution of dorsal and ventral medial prefrontal cortex to the acquisition and extinction of conditioned fear in rats Behav. Neurosci. 109 1995 681 688
30. L.P. Morin, and R.I. Wood A Stereotaxic Atlas of the Golden Hamster Brain 2001 Academic Press San Diego, CA
31. M. Potegal, K. Huhman, T. Moore, and J. Meyerhoff Conditioned defeat in the Syrian golden hamster (Mesocricetus auratus) Behav. Neural Biol. 60 1993 93 102
32. G.J. Quirk, E. Likhtik, J.G. Pelletier, and D. Paré Stimulation of medial prefrontal cortex decreases responsiveness of central amygdala output neurons J. Neurosci. 23 2003 8800 8807
33. A. Rajadhyaksha, A. Barczak, W. Macias, J.C. Leveque, S.E. Lewis, and C. Konradi L-Type Ca(2+) channels are essential for glutamate-mediated CREB phosphorylation and c-fos gene expression in striatal neurons J. Neurosci. 19 1999 6348 6359
34. B. Sacchetti, E. Baldi, C.A. Lorenzini, and C. Bucherelli Differential contribution of some cortical sites to the formation of memory traces supporting fear conditioning Exp. Brain Res. 146 2002 223 232
35. E. Santini, H. Ge, K. Ren, S. Peña de Ortiz, and G.J. Quirk Consolidation of fear extinction requires protein synthesis in the medial prefrontal cortex J. Neurosci. 24 2004 5704 5710
36. G.E. Schafe, and J.E. LeDoux Memory consolidation of auditory pavlovian fear conditioning requires protein synthesis and protein kinase A in the amygdala J. Neurosci. 20 2000 RC96
37. B. Schulz, M. Fendt, F. Gasparini, K. Lingenhöhl, R. Kuhn, and M. Koch The metabotropic glutamate receptor antagonist 2-methyl-6-(phenylethynyl)- pyridine (MPEP) blocks fear conditioning in rats Neuropharmacology 41 2001 1 7
38. D. Sierra-Mercado Jr., K.A. Cocoran, K. Lebrón-Milad, and G.J. Quirk Inactivation of the ventromedial prefrontal cortex reduces expression of conditioned fear and impairs subsequent recall of extinction Eur. J. Neurosci. 24 2006 1751 1758
39. Y. Smith, J.F. Paré, and D. Paré Differential innervation of parvalbumin-immunoreactive interneurons of the basolateral amygdaloid complex by cortical and intrinsic inputs J. Comp. Neurol. 416 2000 496 508
40. R.M. Vouimba, R. Garcia, M. Baudry, and R.F. Thompson Potentiation of conditioned freezing following dorsomedial prefrontal cortex lesions does not interfere with fear reduction in mice Behav. Neurosci. 114 2000 720 724
41. D.L. Walker, and M. Davis The role of amygdala glutamate receptors in fear learning, fear-potentiated startle, and extinction Pharmacol. Biochem. Behav. 71 2002 379 392
42. D.L. Walker, G.Y. Paschall, and M. Davis Glutamate receptor antagonist infusions into the basolateral and medial amygdala reveal differential contributions to olfactory vs. context fear conditioning and expression Learn. Mem. 12 2005 120 129
43. Y. Zhang, H. Fukushima, and S. Kida Induction and requirement of gene expression in the anterior cingulated cortex and medial prefrontal cortex for the consolidation of inhibitory avoidance memory Mol. Brain 4 2011 1 11