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Volumn 415, Issue 2, 2011, Pages 416-420

Anticancer drug irinotecan inhibits homomeric 5-HT 3A and heteromeric 5-HT 3AB receptor responses

Author keywords

5 HT; 5 HT 3 receptor; Anti cancer; Anti emetic; Ion channel; Vagus nerve

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; IRINOTECAN; SEROTONIN 3A RECEPTOR; SEROTONIN 3B RECEPTOR;

EID: 84855896511     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.10.084     Document Type: Article
Times cited : (7)

References (35)
  • 1
    • 0023552964 scopus 로고
    • Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothec in, a novel water-soluble derivative of camptothecin, against murine tumors
    • Kunimoto T., Nitta K., Tanaka T., Uehara N., Baba H., Takeuchi M., Yokokura T., Sawada S., Miyasaka T., Mutai M. Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothec in, a novel water-soluble derivative of camptothecin, against murine tumors. Cancer Res. 1987, 47:5944-5947.
    • (1987) Cancer Res. , vol.47 , pp. 5944-5947
    • Kunimoto, T.1    Nitta, K.2    Tanaka, T.3    Uehara, N.4    Baba, H.5    Takeuchi, M.6    Yokokura, T.7    Sawada, S.8    Miyasaka, T.9    Mutai, M.10
  • 2
    • 0025996996 scopus 로고
    • Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11
    • Kawato Y., Aonuma M., Hirota Y., Kuga H., Sato K. Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer Res. 1991, 51:4187-4191.
    • (1991) Cancer Res. , vol.51 , pp. 4187-4191
    • Kawato, Y.1    Aonuma, M.2    Hirota, Y.3    Kuga, H.4    Sato, K.5
  • 3
    • 0025342506 scopus 로고
    • Nonlinear pharmacokinetics of CPT-11 in rats
    • Kaneda N., Yokokura T. Nonlinear pharmacokinetics of CPT-11 in rats. Cancer Res. 1990, 50:1721-1725.
    • (1990) Cancer Res. , vol.50 , pp. 1721-1725
    • Kaneda, N.1    Yokokura, T.2
  • 4
    • 0030826929 scopus 로고    scopus 로고
    • Topoisomerase I inhibitors: review and update
    • Rothenberg M.L. Topoisomerase I inhibitors: review and update. Ann. Oncol. 1997, 8:837-855.
    • (1997) Ann. Oncol. , vol.8 , pp. 837-855
    • Rothenberg, M.L.1
  • 6
    • 0028158012 scopus 로고
    • Phase I and pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks
    • Rowinsky E.K., Grochow L.B., Ettinger D.S., Sartorius S.E., Lubejko B.G., Chen T.L., Rock M.K., Donehower R.C. Phase I and pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks. Cancer Res. 1994, 54:427-436.
    • (1994) Cancer Res. , vol.54 , pp. 427-436
    • Rowinsky, E.K.1    Grochow, L.B.2    Ettinger, D.S.3    Sartorius, S.E.4    Lubejko, B.G.5    Chen, T.L.6    Rock, M.K.7    Donehower, R.C.8
  • 8
    • 70549101203 scopus 로고    scopus 로고
    • Overview on 5-HT receptors and their role in physiology and pathology of the central nervous system
    • Filip M., Bader M. Overview on 5-HT receptors and their role in physiology and pathology of the central nervous system. Pharmacol. Rep. 2009, 61:761-777.
    • (2009) Pharmacol. Rep. , vol.61 , pp. 761-777
    • Filip, M.1    Bader, M.2
  • 10
    • 0037835606 scopus 로고    scopus 로고
    • Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E
    • Niesler B., Frank B., Kapeller J., Rappold G.A. Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E. Gene 2003, 310:101-111.
    • (2003) Gene , vol.310 , pp. 101-111
    • Niesler, B.1    Frank, B.2    Kapeller, J.3    Rappold, G.A.4
  • 12
    • 0034523098 scopus 로고    scopus 로고
    • Stratified administration of serotonin 5-HT3 receptor antagonists (setrons) for chemotherapy-induced emesis. Economic implications
    • Sanchez L.A., Holdsworth M., Bartel S.B. Stratified administration of serotonin 5-HT3 receptor antagonists (setrons) for chemotherapy-induced emesis. Economic implications. Pharmacoeconomics 2000, 18:533-556.
    • (2000) Pharmacoeconomics , vol.18 , pp. 533-556
    • Sanchez, L.A.1    Holdsworth, M.2    Bartel, S.B.3
  • 13
    • 0025997336 scopus 로고
    • Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel
    • Maricq A.V., Peterson A.S., Brake A.J., Myers R.M., Julius D. Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel. Science 1991, 254:432-437.
    • (1991) Science , vol.254 , pp. 432-437
    • Maricq, A.V.1    Peterson, A.S.2    Brake, A.J.3    Myers, R.M.4    Julius, D.5
  • 14
    • 0021770860 scopus 로고
    • Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs
    • Krieg P.A., Melton D.A. Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs. Nucleic Acids Res. 1984, 12:7057-7070.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 7057-7070
    • Krieg, P.A.1    Melton, D.A.2
  • 15
    • 0037333916 scopus 로고    scopus 로고
    • The GABA(A) receptor antagonist picrotoxin inhibits 5-hydroxytryptamine type 3A receptors
    • Das P., Bell-Horner C.L., Machu T.K., Dillon G.H. The GABA(A) receptor antagonist picrotoxin inhibits 5-hydroxytryptamine type 3A receptors. Neuropharmacology 2003, 44:431-438.
    • (2003) Neuropharmacology , vol.44 , pp. 431-438
    • Das, P.1    Bell-Horner, C.L.2    Machu, T.K.3    Dillon, G.H.4
  • 16
    • 23044495814 scopus 로고    scopus 로고
    • Modulation of human 5-hydroxytryptamine type 3AB receptors by volatile anesthetics and n-alcohols
    • Stevens R., Rusch D., Solt K., Raines D.E., Davies P.A. Modulation of human 5-hydroxytryptamine type 3AB receptors by volatile anesthetics and n-alcohols. J. Pharmacol. Exp. Ther. 2005, 314:338-345.
    • (2005) J. Pharmacol. Exp. Ther. , vol.314 , pp. 338-345
    • Stevens, R.1    Rusch, D.2    Solt, K.3    Raines, D.E.4    Davies, P.A.5
  • 17
    • 27944482252 scopus 로고    scopus 로고
    • Co-expression of the 5-HT(3B) subunit with the 5-HT(3A) receptor reduces alcohol sensitivity
    • Hayrapetyan V., Jenschke M., Dillon G.H., Machu T.K. Co-expression of the 5-HT(3B) subunit with the 5-HT(3A) receptor reduces alcohol sensitivity. Brain Res. Mol. Brain Res. 2005, 142:146-150.
    • (2005) Brain Res. Mol. Brain Res. , vol.142 , pp. 146-150
    • Hayrapetyan, V.1    Jenschke, M.2    Dillon, G.H.3    Machu, T.K.4
  • 18
    • 0030249075 scopus 로고    scopus 로고
    • Irinotecan (CPT-11): pharmacology and clinical applications
    • Masuda N., Kudoh S., Fukuoka M. Irinotecan (CPT-11): pharmacology and clinical applications. Crit. Rev. Oncol. Hematol. 1996, 24:3-26.
    • (1996) Crit. Rev. Oncol. Hematol. , vol.24 , pp. 3-26
    • Masuda, N.1    Kudoh, S.2    Fukuoka, M.3
  • 19
    • 33749249529 scopus 로고    scopus 로고
    • Irinotecan in the treatment of colorectal cancer
    • Fuchs C., Mitchell E.P., Hoff P.M. Irinotecan in the treatment of colorectal cancer. Cancer Treat. Rev. 2006, 32:491-503.
    • (2006) Cancer Treat. Rev. , vol.32 , pp. 491-503
    • Fuchs, C.1    Mitchell, E.P.2    Hoff, P.M.3
  • 20
    • 0032512796 scopus 로고    scopus 로고
    • Oral versus intraperitoneal administration of irinotecan in the treatment of human neuroblastoma in nude mice
    • Choi S.H., Tsuchida Y., Yang H.W. Oral versus intraperitoneal administration of irinotecan in the treatment of human neuroblastoma in nude mice. Cancer Lett. 1998, 124:15-21.
    • (1998) Cancer Lett. , vol.124 , pp. 15-21
    • Choi, S.H.1    Tsuchida, Y.2    Yang, H.W.3
  • 21
    • 0027242140 scopus 로고
    • Relationship between development of diarrhea and the concentration of SN-38, an active metabolite of CPT-11, in the intestine and the blood plasma of athymic mice following intraperitoneal administration of CPT-11
    • Araki E., Ishikawa M., Iigo M., Koide T., Itabashi M., Hoshi A. Relationship between development of diarrhea and the concentration of SN-38, an active metabolite of CPT-11, in the intestine and the blood plasma of athymic mice following intraperitoneal administration of CPT-11. Jpn. J. Cancer Res. 1993, 84:697-702.
    • (1993) Jpn. J. Cancer Res. , vol.84 , pp. 697-702
    • Araki, E.1    Ishikawa, M.2    Iigo, M.3    Koide, T.4    Itabashi, M.5    Hoshi, A.6
  • 22
    • 0028854897 scopus 로고
    • Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients
    • Abigerges D., Chabot G.G., Armand J.P., Herait P., Gouyette A., Gandia D. Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients. J. Clin. Oncol. 1995, 13:210-221.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 210-221
    • Abigerges, D.1    Chabot, G.G.2    Armand, J.P.3    Herait, P.4    Gouyette, A.5    Gandia, D.6
  • 24
    • 0010917253 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of irinotecan during a phase II clinical trial in colorectal cancer. Pharmacology and Molecular Mechanisms Group of the European Organization for Research and Treatment of Cancer
    • Canal P., Gay C., Dezeuze A., Douillard J.Y., Bugat R., Brunet R., Adenis A., Herait P., Lokiec F., Mathieu-Boue A. Pharmacokinetics and pharmacodynamics of irinotecan during a phase II clinical trial in colorectal cancer. Pharmacology and Molecular Mechanisms Group of the European Organization for Research and Treatment of Cancer. J. Clin. Oncol. 1996, 14:2688-2695.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 2688-2695
    • Canal, P.1    Gay, C.2    Dezeuze, A.3    Douillard, J.Y.4    Bugat, R.5    Brunet, R.6    Adenis, A.7    Herait, P.8    Lokiec, F.9    Mathieu-Boue, A.10
  • 25
    • 45849139026 scopus 로고    scopus 로고
    • Irinotecan-induced central nervous system toxicity. Report on two cases and review of the literature
    • Hamberg P., De Jong F.A., Brandsma D., Verweij J., Sleijfer S. Irinotecan-induced central nervous system toxicity. Report on two cases and review of the literature. Acta Oncol. 2008, 47:974-978.
    • (2008) Acta Oncol. , vol.47 , pp. 974-978
    • Hamberg, P.1    De Jong, F.A.2    Brandsma, D.3    Verweij, J.4    Sleijfer, S.5
  • 27
    • 0023748878 scopus 로고
    • Serotonergic status in human blood
    • Ortiz J., Artigas F., Gelpi E. Serotonergic status in human blood. Life Sci. 1988, 43:983-990.
    • (1988) Life Sci. , vol.43 , pp. 983-990
    • Ortiz, J.1    Artigas, F.2    Gelpi, E.3
  • 28
    • 0026643829 scopus 로고
    • Changes in serotonin metabolism in cancer patients: its relationship to nausea and vomiting induced by chemotherapeutic drugs
    • Cubeddu L.X., Hoffmann I.S., Fuenmayor N.T., Malave J.J. Changes in serotonin metabolism in cancer patients: its relationship to nausea and vomiting induced by chemotherapeutic drugs. Br. J. Cancer 1992, 66:198-203.
    • (1992) Br. J. Cancer , vol.66 , pp. 198-203
    • Cubeddu, L.X.1    Hoffmann, I.S.2    Fuenmayor, N.T.3    Malave, J.J.4
  • 29
    • 0028986508 scopus 로고
    • Plasma chromogranin A: a marker of serotonin release and of emesis associated with cisplatin chemotherapy
    • Cubeddu L.X., O'Connor D.T., Parmer R.J. Plasma chromogranin A: a marker of serotonin release and of emesis associated with cisplatin chemotherapy. J. Clin. Oncol. 1995, 13:681-687.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 681-687
    • Cubeddu, L.X.1    O'Connor, D.T.2    Parmer, R.J.3
  • 30
    • 0028985355 scopus 로고
    • Detection of 5-HT3R-A, a 5-HT3 receptor subunit, in submucosal and myenteric ganglia of rat small intestine using in situ hybridization
    • Johnson D.S., Heinemann S.F. Detection of 5-HT3R-A, a 5-HT3 receptor subunit, in submucosal and myenteric ganglia of rat small intestine using in situ hybridization. Neurosci. Lett. 1995, 184:67-70.
    • (1995) Neurosci. Lett. , vol.184 , pp. 67-70
    • Johnson, D.S.1    Heinemann, S.F.2
  • 31
    • 0036703991 scopus 로고    scopus 로고
    • Differential composition of 5-hydroxytryptamine3 receptors synthesized in the rat CNS and peripheral nervous system
    • Morales M., Wang S.D. Differential composition of 5-hydroxytryptamine3 receptors synthesized in the rat CNS and peripheral nervous system. J. Neurosci. 2002, 22:6732-6741.
    • (2002) J. Neurosci. , vol.22 , pp. 6732-6741
    • Morales, M.1    Wang, S.D.2
  • 33
    • 0027339690 scopus 로고
    • Modulation by 5-HT3 and 5-HT4 receptors of the release of 5-hydroxytryptamine from the guinea-pig small intestine
    • Gebauer A., Merger M., Kilbinger H. Modulation by 5-HT3 and 5-HT4 receptors of the release of 5-hydroxytryptamine from the guinea-pig small intestine. Naunyn Schmiedebergs Arch. Pharmacol. 1993, 347:137-140.
    • (1993) Naunyn Schmiedebergs Arch. Pharmacol. , vol.347 , pp. 137-140
    • Gebauer, A.1    Merger, M.2    Kilbinger, H.3
  • 35
    • 0037868158 scopus 로고    scopus 로고
    • Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients
    • Tremblay P.B., Kaiser R., Sezer O., Rosler N., Schelenz C., Possinger K., Roots I., Brockmoller J. Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients. J. Clin. Oncol. 2003, 21:2147-2155.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 2147-2155
    • Tremblay, P.B.1    Kaiser, R.2    Sezer, O.3    Rosler, N.4    Schelenz, C.5    Possinger, K.6    Roots, I.7    Brockmoller, J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.