Aberrant activation of Wnt/β-catenin signaling pathway contributes to the sequential progression of DMBA-induced HBP carcinomas

Oral Oncology

Volumn 48, Issue 1, 2012, Pages 33-39

  Vidya Priyadarsini, Ramamurthi ^a   Senthil Murugan, Ramalingam ^a   Nagini, Siddavaram ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Catenin; DMBA; Hamster buccal pouch; Wnt

Indexed keywords

APC PROTEIN; AXIN 1; BETA ACTIN; BETA CATENIN; CYCLIN D1; DIMETHYLBENZ[A]ANTHRACENE; DISHEVELLED PROTEIN; GELATINASE A; GELATINASE B; GLYCOGEN SYNTHASE KINASE 3BETA; LYMPHOID ENHANCER FACTOR 1; PROTEIN FZ; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN; WNT1 PROTEIN; WNT3 PROTEIN; WNT4 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOACCUMULATION; CANCER GROWTH; CANCER INVASION; CARCINOGENESIS; CELL ADHESION; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; HYPERPLASIA; INVASIVE CARCINOMA; MALE; MALIGNANT TRANSFORMATION; MOUTH CARCINOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; SYRIAN HAMSTER; WESTERN BLOTTING;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; BETA CATENIN; BLOTTING, WESTERN; CARCINOGENS; CARCINOMA, SQUAMOUS CELL; CHEEK; CRICETINAE; MALE; MESOCRICETUS; MOUTH NEOPLASMS; NEOPLASMS, EXPERIMENTAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84855887517     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2011.08.008     Document Type: Article

References (24)

1. R. Nusse Wnt signaling in disease and in development Cell Res 15 2005 28 32 (Pubitemid 41653961)
2. K. Willert, and K.A. Jones Wnt signaling: is the party in the nucleus? Genes Dev 20 2006 1394 1404 (Pubitemid 43830647)
3. T. Akiyama Wnt/-catenin signaling Cytokine Growth Factor Rev 11 2000 273 282
4. J.K. Kundu, K.Y. Choi, and Y.J. Surh β-Catenin-mediated signaling: a novel molecular target for chemoprevention with anti-inflammatory substances Biochim Biophys Acta 1765 2006 14 24
5. J.H. Van Es, N. Barker, and H. Clevers You Wnt some you lose some: oncogenesis in the Wnt signaling pathway Curr Opin Genet Dev 13 2003 28 33 (Pubitemid 36143924)
6. J.P. Alao The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention Mol Cancer 6 2007 24
7. D. Bourboulia, and W.G. Stetler-Stevenson Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): positive and negative regulators in tumor cell adhesion Semin Cancer Biol 20 2010 161 168
8. M. Uraguchi, M. Morikawa, M. Shirakawa, K. Sanada, and K. Imai Activation of WNT family expression and signaling in squamous cell carcinomas of the oral cavity J Dent Res 83 2004 327 332 (Pubitemid 41713770)
9. S. Iwai, W. Katagiri, C.K.S. Amekawa, M. Nakazawa, and Y. Yura Mutations of the APC, beta-catenin, and axin 1 genes and cytoplasmic accumulation of beta-catenin in oral squamous cell carcinoma J Cancer Res Clin Oncol 131 2005 773 782 (Pubitemid 41630700)
10. W.M. Zhang, L. Lo Muzio, C. Rubini, and G. Yan Effect of Wnt-1 on beta-catenin expression and its relation to Ki-67 and tumor differentiation in oral squamous cell carcinoma Oncol Rep 13 2005 1095 1099
11. T. Odajima, Y. Sasaki, N. Tanaka, Y. Kato-Mori, H. Asanuma, and T. Ikeda Abnormal-catenin expression in oral cancer with no gene mutation: correlation with expression of cyclin D1 and epidermal growth factor receptor, Ki-67 labeling index, and clinicopathological features Human Pathol 36 2005 234 241 (Pubitemid 40404006)
12. N. Tanaka, T. Odajima, K. Ogi, T. Ikeda, and M. Satoh Expression of E-cadherin, α-catenin, and β-catenin in the process of lymph node metastasis in oral squamous cell carcinoma Br J Cancer 89 2003 557 563 (Pubitemid 37026443)
13. K. Ishida, S. Ito, N. Wada, H. Deguchi, T. Hata, and M. Hosoda Mol Cancer 6 2007 62
14. S. Nagini, P. Vidjaya Letchoumy, A. Thangavelu, and C.R. Ramachandran Of humans and hamsters: a comparative evaluation of carcinogen activation, DNA damage, cell proliferation, apoptosis, invasion, and angiogenesis in oral cancer patients and hamster buccal pouch carcinomas Oral Oncol 45 2009 e31 37
15. S. Nagini Of humans and hamsters: The hamster buccal pouch carcinogenesis model as a paradigm for oral oncogenesis and chemoprevention Anticancer Agents Med Chem 9 2009 843 852
16. S. Legrand-Poels, S. Schoonbrodt, and J. Piette Regulation of interleukin-6 gene expression by pro-inflammatory cytokines in a colon cancer cell line Biochem J 349 2000 765 773 (Pubitemid 30609407)
17. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 1976 248 254
18. L. Queimado, D. Obeso, M.D. Hatfield, Y. Yang, D.M. Thompson, and A.M.C. Reis Dysregulation of Wnt pathway components in human salivary gland tumors Arch Otolaryngol Head Neck Surg 134 2008 94 101 (Pubitemid 351159282)
19. C.S. Rhee, M. Sen, D. Lu, C. Wu, L. Leoni, and J. Rubin Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas Oncogene 21 2002 6598 6605 (Pubitemid 35177038)
20. K. Kawakami, H. Hirata, S. Yamamura, N. Kikuno, S. Saini, and S. Majid Functional significance of Wnt inhibitory factor-1 gene in kidney cancer Cancer Res 69 2009 8603 8610
21. L. Lo Muzio, S. Staibano, G. Pannone, M. Grieco, M.D. Mignogna, and A. Cerrato Beta- and gamma-catenin expression in oral squamaous cell carcinomas Anticancer Res 19 1999 3817 3826
22. H.K. Williams, D.S.A. Sanders, J.A.Z. Jankowski, G. Landini, and A.M.S. Brown Expression of cadherins and catenins in oral epithelial dysplasia and squamous cell carcinoma J Oral Pathol Med 27 1998 308 317 (Pubitemid 28382637)
23. R. Tsuchiya, G. Yamamoto, Y. Nagoshi, T. Aida, T. Irie, and T. Tachikawa Expression of adenomatous polyposis coli (APC) in tumorigenesis of human oral squamous cell carcinoma Oral Oncol 40 2004 932 940 (Pubitemid 39369566)
24. O. Tetsu, and F. McCormick β-Catenin regulates expression of cyclin D1 in colon carcinoma cells Nature 398 1999 422 426 (Pubitemid 29180374)