메뉴 건너뛰기




Volumn 827, Issue , 2012, Pages 87-95

Posttranslational lipid modification of rho family small GTPases

Author keywords

CAAX motif; Farnesylation; Geranylgeranylation; Isoprenylcysteine carboxyl methyltransferase; Palmitoylation; Ras converting enzyme 1

Indexed keywords

LIPID; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 84855884600     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-442-1_6     Document Type: Article
Times cited : (20)

References (21)
  • 1
    • 16644370412 scopus 로고    scopus 로고
    • Human RAS superfamily roteins and related GTPases
    • Colicelli, J. (2004) Human RAS superfamily roteins and related GTPases. Sci STKE 2004(250), RE13.
    • (2004) Sci STKE , vol.2004 , Issue.250
    • Colicelli, J.1
  • 2
    • 16844387479 scopus 로고    scopus 로고
    • The Ras superfamily at a glance
    • DOI 10.1242/jcs.01660
    • Wennerberg, K., Rossman, K.L., and Der, C.J. (2005) The Ras superfamily at a glance. J Cell Sci 118, 843-846. (Pubitemid 40484876)
    • (2005) Journal of Cell Science , vol.118 , Issue.5 , pp. 843-846
    • Wennerberg, K.1    Rossman, K.L.2    Der, C.J.3
  • 3
    • 13444252631 scopus 로고    scopus 로고
    • GEF means go: Turning on Rho GTPases with guanine nucleotide-exchange factors
    • DOI 10.1038/nrm1587
    • Rossman, K.L., Der, C.J., and Sondek, J. (2005) GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol 6, 167-180. (Pubitemid 40215811)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.2 , pp. 167-180
    • Rossman, K.L.1    Der, C.J.2    Sondek, J.3
  • 4
    • 0027984138 scopus 로고
    • GAPs for rhorelated GTPases
    • Lamarche, N., and Hall, A. (1994) GAPs for rhorelated GTPases. Trends Genet 10, 436-440.
    • (1994) Trends Genet , vol.10 , pp. 436-440
    • Lamarche, N.1    Hall, A.2
  • 5
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • DOI 10.1038/nature01148
    • Etienne-Manneville, S., and Hall, A. (2002) Rho GTPases in cell biology. Nature 420, 629-635. (Pubitemid 36764489)
    • (2002) Nature , vol.420 , Issue.6916 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 6
    • 4644370323 scopus 로고    scopus 로고
    • Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity
    • DOI 10.1016/j.jmb.2004.08.056, PII S0022283604010472
    • Reid, T.S., Terry, K.L., Casey, P.J., and Beese, L.S. (2004) Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. J Mol Biol 343, 417-433. (Pubitemid 39296875)
    • (2004) Journal of Molecular Biology , vol.343 , Issue.2 , pp. 417-433
    • Scott Reid, T.1    Terry, K.L.2    Casey, P.J.3    Beese, L.S.4
  • 7
    • 0031945668 scopus 로고    scopus 로고
    • CaaX converting enzymes
    • DOI 10.1097/00041433-199804000-00004
    • Ashby, M.N. (1998) CaaX converting enzymes. Curr Opin Lipidol 9, 99-102. (Pubitemid 28159706)
    • (1998) Current Opinion in Lipidology , vol.9 , Issue.2 , pp. 99-102
    • Ashby, M.N.1
  • 8
    • 0030909336 scopus 로고    scopus 로고
    • Modulation of ras and a-factor function by carboxyl-terminal proteolysis
    • DOI 10.1126/science.275.5307.1796
    • Boyartchuk, V.L., Ashby, M.N., and Rine, J. (1997) Modulation of Ras and a-factor function by carboxyl-terminal proteolysis. Science 275, 1796-1800. (Pubitemid 27136718)
    • (1997) Science , vol.275 , Issue.5307 , pp. 1796-1800
    • Boyartchuk, V.L.1    Ashby, M.N.2    Rine, J.3
  • 9
    • 0025764049 scopus 로고
    • The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins
    • Hrycyna, C.A., Sapperstein, S.K., Clarke, S., and Michaelis, S. (1991) The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins. EMBO J 10, 1699-1709. (Pubitemid 21905637)
    • (1991) EMBO Journal , vol.10 , Issue.7 , pp. 1699-1709
    • Hrycyna, C.A.1    Sapperstein, S.K.2    Clarke, S.3    Michaelis, S.4
  • 10
    • 1342331479 scopus 로고    scopus 로고
    • Searching for the elusive targets of farnesyltransferase inhibitors
    • Sebti, S.M., and Der, C.J. (2003) Opinion: Searching for the elusive targets of farnesyltransferase inhibitors. Nat Rev Cancer 3, 945-951. (Pubitemid 37500179)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.12 , pp. 945-951
    • Sebti, S.M.1    Der, C.J.2
  • 11
    • 18344394166 scopus 로고    scopus 로고
    • Post-prenylation-processing enzymes as new targets in oncogenesis
    • DOI 10.1038/nrc1612
    • Winter-Vann, A.M., and Casey, P.J. (2005) Postprenylation- processing enzymes as new targets in oncogenesis. Nat Rev Cancer 5, 405-412. (Pubitemid 40637832)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.5 , pp. 405-412
    • Winter-Vann, A.M.1    Casey, P.J.2
  • 12
    • 0035825193 scopus 로고    scopus 로고
    • Differential localization of Rho GTPases in live cells: Regulation by hypervariable regions and RhoGDI binding
    • DOI 10.1083/jcb.152.1.111
    • Michaelson, D., Silletti, J., Murphy, G., Eustachio, P., Rush, and M., Philips, M.R. (2001) Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding. J Cell Biol 152, 111-126. (Pubitemid 32102441)
    • (2001) Journal of Cell Biology , vol.152 , Issue.1 , pp. 111-126
    • Michaelson, D.1    Silletti, J.2    Murphy, G.3    D'Eustachio, P.4    Rush, M.5    Philips, M.R.6
  • 13
    • 17144379674 scopus 로고    scopus 로고
    • Critical and distinct roles of amino- and carboxyl-terminal sequences in regulation of the biological activity of the Chp atypical Rho GTPase
    • DOI 10.1074/jbc.M411300200
    • Chenette, E.J., Abo, A., and Der, C.J. (2005) Critical and distinct roles of amino- and carboxyl- terminal sequences in regulation of the biological activity of the Chp atypical Rho GTPase. J Biol Chem 280, 13784-13792. (Pubitemid 40517275)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.14 , pp. 13784-13792
    • Chenette, E.J.1    Abo, A.2    Der, C.J.3
  • 14
    • 25444481924 scopus 로고    scopus 로고
    • Transforming activity of the Rho family GTPase, Wrch-1, a Wnt-regulated Cdc42 homolog, is dependent on a novel carboxyl-terminal palmitoylation motif
    • DOI 10.1074/jbc.M507362200
    • Berzat, A.C., Buss, J.E., Chenette, E.J., Weinbaum, C.A., Shutes, A., Der, C.J., Minden, A., Cox, A.D. (2005) Transforming activity of the Rho family GTPase, Wrch-1, a Wntregulated Cdc42 homolog, is dependent on a novel carboxyl-terminal palmitoylation motif. J Biol Chem 280, 33055-33065. (Pubitemid 41368355)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.38 , pp. 33055-33065
    • Berzat, A.C.1    Buss, J.E.2    Chenette, E.J.3    Weinbaum, C.A.4    Shutes, A.5    Der, C.J.6    Minden, A.7    Cox, A.D.8
  • 17
    • 0033214457 scopus 로고    scopus 로고
    • Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I: Combination therapy with the cytotoxic agents cisplatin, taxol, and gemcitabine
    • Sun, J., Blaskovich, M.A., Knowles, D., Qian, Y., Ohkanda, J., Bailey, R.D., Hamilton, A.D., and Sebti, S.M. (1999) Antitumor effi cacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and eranylgeranyltransferase I: combination therapy with the cytotoxic agents cisplatin, Taxol, and gemcitabine. Cancer Res 59, 4919-4926. (Pubitemid 29472897)
    • (1999) Cancer Research , vol.59 , Issue.19 , pp. 4919-4926
    • Sun, J.1    Blaskovich, M.A.2    Knowles, D.3    Qian, Y.4    Ohkanda, J.5    Bailey, R.D.6    Hamilton, A.D.7    Sebti, S.M.8
  • 18
    • 0029926493 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation
    • DOI 10.1074/jbc.271.44.27402
    • McGuire, T.F., Qian, Y., Vogt, A., Hamilton, A.D., and Sebti, S.M. (1996) Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation. J Biol Chem 271, 27402-27407. (Pubitemid 26367297)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.44 , pp. 27402-27407
    • McGuire, T.F.1    Qian, Y.2    Vogt, A.3    Hamilton, A.D.4    Sebti, S.M.5
  • 19
    • 36048968159 scopus 로고    scopus 로고
    • Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth
    • DOI 10.1128/MCB.00057-07
    • Falsetti, S.C., Wang, D.A., Peng, H., Carrico, D., Cox, A.D., Der, C.J., Hamilton, A.D., and Sebti,.S.M. (2007) Geranylgeranyltransferase I inhibitors target RalB to inhibit anchoragedependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth. Mol Cell Biol 27, 8003-8014. (Pubitemid 350086432)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.22 , pp. 8003-8014
    • Falsetti, S.C.1    Wang, D.-A.2    Peng, H.3    Carrico, D.4    Cox, A.D.5    Der, C.J.6    Hamilton, A.D.7    Sebti, S.M.8
  • 20
    • 0842266583 scopus 로고    scopus 로고
    • Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion
    • DOI 10.1083/jcb.200311093
    • Bivona, T.G., Wiener, H.H., Ahearn, I.M., Silletti, J., Chiu, V.K., and Philips, M.R. (2004) Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion. J Cell Biol 164, 461-470. (Pubitemid 38174773)
    • (2004) Journal of Cell Biology , vol.164 , Issue.3 , pp. 461-470
    • Bivona, T.G.1    Wiener, H.H.2    Ahearn, I.M.3    Silletti, J.4    Chiu, V.K.5    Philips, M.R.6
  • 21
    • 0842266659 scopus 로고    scopus 로고
    • Labeling and quantifying sites of protein palmitoylation
    • Drisdel, R.C., and Green, W.N. (2004) Labeling and quantifying sites of protein palmitoylation. Biotechniques 36, 276-285. (Pubitemid 38174735)
    • (2004) BioTechniques , vol.36 , Issue.2 , pp. 276-285
    • Drisdel, R.C.1    Green, W.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.