Altered excitability of cultured chromaffin cells following exposure to multi-walled carbon nanotubes

Nanotoxicology

Volumn 6, Issue 1, 2012, Pages 47-60

  Gavello, Daniela ^a,b   Vandael, David H F ^a   Cesa, Roberta ^a,d   Premoselli, Federica ^a   Marcantoni, Andrea ^a,b   Cesano, Federico ^a,b   Scarano, Domenica ^a,b   Fubini, Bice ^a,b,c   Carbone, Emilio ^a,b,d   Fenoglio, Ivana ^a,b,c   Carabelli, Valentina ^a,b,d  

^a UNIVERSITY OF TURIN   (Italy)

^b Interdepartimental Center for Nanostructured Interfaces and Surfaces   (Italy)

^c Interdepartimental Center G Scansetti for Studies on Asbestos and Other Toxic Particulates   (Italy)

^d National Institute of Neuroscience   (Italy)

Author keywords

Action potential firing; Adrenal chromaffin cells; Ca 2+ and BK channels; Input resistance; MWCNTs; Voltage gated Na + and K+ channels

Indexed keywords

MULTI WALLED NANOTUBE; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL MEMBRANE; CELL SURVIVAL; CHROMAFFIN CELL; CONTROLLED STUDY; CYTOTOXICITY; INTERNALIZATION; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; TRANSMISSION ELECTRON MICROSCOPY;

ACTION POTENTIALS; ANIMALS; CALCIUM CHANNELS; CELL COUNT; CELL MEMBRANE; CELL SURVIVAL; CELLS, CULTURED; CHROMAFFIN CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; ION CHANNELS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MICE; NANOTUBES, CARBON; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, VOLTAGE-GATED;

EID: 84855880996     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2011.553294     Document Type: Article

References (47)

1. Al Faraj A, Cieslar K, Lacroix G, Gaillard S, Canet-Soulas E, Crémillieux Y. 2009. In vivo imaging of carbon nanotube biodistribution using magnetic resonance imaging. Nano Lett 9(3):1023-1027.
2. Belyanskaya L, Weigel S, Hirsch C, Tobler U, Krug HF, Wick P. 2009. Effects of carbon nanotubes on primary neurons and glial cells. Neurotoxicology 30(4):702-711.
3. Chan CS, Guzman JN, Llijic E, Mercer JN, Rick C, Tkacth T, Meredith GE, Surmeier DJ. 2007. Rejuvenation protects neurons in mouse models of Parkinson's disease. Nature 447(7148):1081-1086. (Pubitemid 47014425)
4. Deng X, Jia G, Wang H, Sun H, Wang X, Yang S, Wang T, Liu Y. 2007. Translocation and fate of multi-walled carbon nanotubes in vivo. Carbon 45:1419-1424. (Pubitemid 46829028)
5. Donaldson K, Aitken R, Tran L, Stone V, Duffin R, Forrest G, Alexander A. 2006. Carbon nanotubes: A review of their properties in relation to pulmonary toxicology and workplace safety. Toxicol Sci 92(1):5-22. (Pubitemid 43985785)
6. Donaldson K, Poland CA. 2009. Nanotoxicology: New insights into nanotubes. Nat Nanotechnol 4(11):708-710.
7. Dugan LL, Turetsky DM, Du C, Lobner D, Wheeler M, Almli CR, Shen CK, Luh TY, Choi DW, Lin TS. 1997. Carboxyfullerenes as neuroprotective agents. Proc Natl Acad Sci USA 94(17):9434-9439. (Pubitemid 27357847)
8. Elder A, Gelein R, Silva V, Feikert T, Opanashuk L, Carter J, Potter R, Maynard A, Ito Y, Finkelstein J, Oberdöster G. 2006. Translocation of inhaled ultrafine manganese oxide particles to the central nervous system. Environ Health Perspect 114(8):1172-1178. (Pubitemid 44184673)
9. Elgrabli D, Abella-Gallart S, Robidel F, Rogerieux F, Boczkowski J, Lacroix G. 2008. Biodistribution and clearance of instilled carbon nanotubes in rat lung. Toxicology 253(1-3):131-136.
10. Elgrabli D, Abella-Gallart S, Aguerre-Chariol O, Robidel F, Rogerieux F, Boczkowski J, Lacroix G. 2007. Effect of BSA on carbon nanotube dispersion for in vivo and in vitro studies. Nanotoxicology 1(4):266-278. (Pubitemid 350293564)
11. Fenoglio I, Greco G, Tomatis M, Muller J, Raymundo-Pinero E, Beguin F, Fonseca A, Nagy JB, Lison D, Fubini B. 2008. Structural defects play a major role in the acute lung toxicity of multi-wall carbon nanotubes: Physico-chemical aspects. Chem Res Toxicol 21:1690-1697.
12. Fubini B, Ghiazza M, Fenoglio I. 2010. Physico-chemical features of engineered nanoparticles relevant to their toxicity. Nanotox-icology 4(4):347-363.
13. Guo L, Morris DG, Liu XY, Vaslet C, Hurt RH, Kane AB. 2007. Iron bioavailability and redox activity in diverse carbon nanotube samples. Chem Mater 19(14):3472-3478. (Pubitemid 47155026)
14. Jakubek LM, Marangoudakis S, Raingo J, Liu X, Lipscombe D, Hurt RH. 2009. The inhibition of neuronal calcium ion channels by trace levels of yttrium released from carbon nanotubes. Biomaterials 30(31):6351-6357.
15. Jin H, Heller DA, Strano M. 2009. Size-dependent cellular uptake and expulsion of single-walled carbon nanotubes: Single particle tracking and a generic uptake molde for manoparticles. ACSNano 3(1):149-158.
16. Jorio A, Saito R., Dresselhaus G, Dresselhaus MS. 2004. Determination of nanotubes properties by Raman spectroscopy Philosoph. Trans Royal Soc A-Mat Phys Engin Sci 362:2311-36. (Pubitemid 39518771)
17. Kane AB, Hurt RH. 2008. Nanotoxicology: The asbestos analogy revisited. Nat Nanotechnol 3(7):378-379. (Pubitemid 351948250)
18. Kostarelos K, Lacerda L, Pastorin G, Wy W, Wieckowski S, Luangsivilay J, Godefroy S, Pantarotto D, Briand JP, Muller S, et al. 2007. Cellular uptake of functionalized carbon nanotubes is independent of functional group and cell type. Nat Nanotechnol Lett 2(2):108-112.
19. Kreyling WG, Semmler M, Erbe F, Mayer P, Takenaka S, Schulz H, Oberdörster G, Ziesenis A. 2002. Translocation of ultrafine insoluble iridium particles from lung epithelium to extrapulmonary organs is size dependent but very low. J Toxicol Environ Health A 65(20):1513-1530. (Pubitemid 35217498)
20. Lam CW, James JT, McCluskey R, Arepalli S, Hunter RL. 2006. A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks. Crit Rev Toxicol 36(3):189-217.
21. Lin AMY, Chyi BY, Wang SD, Yu HH, Kanakamma PP, Luh TY, Chou CK, Ho LT. 1999. Carboxyfullerene prevents iron-induced oxidative stress in rat brain. J Neurochem 72(4):1634-1640. (Pubitemid 29140838)
22. Lison D, Muller J. 2008. Lung and systemic responses to carbon nanotubes (CNT) in mice. Toxicol Sci 101(1):179-180.
23. Liu X, Guo L, Morris D, Kane AB, Hurt RH. 2008. Targeted removal of bioavailable metal as a detoxification strategy for carbon nanotubes. Carbon 46(3):489-500.
24. 2+ currents, action potential firing, and quantal size of exocy-tosis in mouse chromaffin cells. Pflügers Archiv Eur J Physiol 457(5):1093-1110.
25. Marcantoni A, Vandael DH, Mahapatra S, Carabelli V, Sinnegger-Brauns MJ, Striessnig J, Carbone E. 2010. Loss of Cav1.3 channels reveals the critical role of L-type and BK-channel coupling in pacemaking mouse adrenal chromaffin cells. J Neurosci 30(2):491-504.
26. Monteiro-Riviere NA, Nemanich RJ, Inman AO, Wang YY, Riviere JE. 2005. Multiwalled carbon nanotube interactions with human epidermal keratinocytes. Toxicol Lett 155(3):377-384. (Pubitemid 40093001)
27. Muller J, Huaux F, Fonseca A, Nagy JB, Moreau N, Delos M, Raymundo-Piñero E, Béguin F, Kirsch-Volders M, Fenoglio I, Fubini B, Lison D. 2008. Structural defects play a major role in the acute lung toxicity of multi-wall carbon nanotubes: Toxico-logical aspects. Chem Res Toxicol 21(9):1698-1705.
28. Muller J, Delos M, Panin N, Rabolli V, Huaux F, Lison D. 2009. Absence of carcinogenic response to multiwall carbon nanotubes in a 2-year bioassay in the peritoneal cavity of the rat. Toxicol Sci 110(2):442-448.
29. Nel A, Xia T, Mädler L, Li N. 2006. Toxic potential of materials at the nanolevel. Science 311(5761):622-627. (Pubitemid 43191298)
30. Nemmar A, Vanbilloen H, Hoylaerts MF. 2001. Passage of intra-tracheally instilled ultrafine particles from the lung into the systemic circulation in hamster. Am J Respir Crit Care Med 164(9):1665-1668. (Pubitemid 33124156)
31. Oberdörster G. 2001. Pulmonary effects of inhaled ultrafine particles. Int Arch Occup Environ Health 74(1):1-8. (Pubitemid 32123735)
32. Oberdörster G, Sharp Z, Atudorei V, Elder A, Gelein R, Lunts A, Kreyling W, Cox C. 2002. Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats. J Toxicol Environ Health A 65(20):1531-1543. (Pubitemid 35217499)
33. Oberdörster G, Sharp Z, Atudorei V, Elder A, Gelein R, Kreyling W, Cox C. 2004. Translocation of inhaled ultrafine particles to the brain. Inhal Toxicol 16(6-7):437-445. (Pubitemid 38685135)
34. Osswald S, Havel M, Gogotsi Y. 2007. Monitoring oxidation of multiwalled carbon nanotubes by Raman spectroscopy. J Raman Spectr 38:728-736.
35. Park KH, Chhowalla M, Iqbal Z, Sesti F. 2003. Single-walled carbon nanotubes are a new class of ion channel blockers. JBC 278:50212-50216. (Pubitemid 37548861)
36. Poland CA, Duffin R, Kinloch I, Maynard A, Wallace WA, Seaton A. 2008. Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol 3(7):423-428.
37. Raffa V, Ciofani G, Vittorio O, Riggio C, Cuschieri A. 2010. Physicochemical properties affecting cellular uptake of carbon nanotubes. Nanomedicine 5(1):89-97.
38. Ryman-Rasmussen JP, Mark F, Cesta MF, Brody AR, Shipley-Phillips JK, Everitt JI, Tewksbury EW, Moss OR, Wong BA, Dodd DE, et al. 2009. Inhaled carbon nano-tubes reach the subpleural tissue in mice. Nat Nanotechnol 4(11):747-751.
39. + channel deficiency. PNAS 101(25):9474-9478. (Pubitemid 38812899)
40. Shvedova AA, Kisin ER, Porter D, Schulte P, Kagan VE, Fadeel B, Castranova V. 2009. Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: Two faces of Janus? Pharmacol Ther 121(2):192-204.
41. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC. 1985. Measurement of protein using bicinchoninic acid. Anal Biochem 150:76-85. (Pubitemid 16258399)
42. Sørensen JB, Nagy G, Varoqueaux F, Nehring RB, Brose N, Wilson MC, Neher E. 2003. Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23. Cell 114(1):75-86. (Pubitemid 36859842)
43. Takagi A, Hirose A, Nishimura T, Fukumori N, Ogata A, Ohashi N, Kitajima S, Kanno J. 2008. Induction of mesotheli-oma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 33(1):105-116. (Pubitemid 351340768)
44. Xu H, Bai J, Meng J, Hao W, Xu H, Cao JM. 2009. Multiwalled carbon nanotubes suppress potassium channel activities in PC12 cells. Nanotechnology 20(28):285102-285111.
45. Yu JR, Grossiord N, Koning CE, Loos J. 2007. Characterization of conductive multiwall carbon nanotube/polystyrene composites prepared by latex technology. Carbon 45(15):618-623.
46. Vandael D, Marcantoni A, Mahapatra S, Caro A, Ruth P, Zuccotti A, Knipper M, Carbone E. 2010. Cav1.3 and BK channel coupling for timing and regulating cell firing. Molec Neurobiol 42:185-198.
47. Zhang Y, Wang B, Meng X, Sun G, Gao C. 2011. Influences of acid-treated multiwalled carbon nanotubes on fibroblasts: Proliferation, adhesion, migration, and wound healing. Ann Biomed Eng 39:414-426.