Loss of Cav1.3 channels reveals the critical role of L-type and BK channel coupling in pacemaking mouse adrenal chromaffin cells

Journal of Neuroscience

Volumn 30, Issue 2, 2010, Pages 491-504

  Marcantoni, Andrea ^a   Vandael, David H F ^a   Mahapatra, Satyajit ^a   Carabelli, Valentina ^a   Sinnegger Brauns, Martina J ^b   Striessnig, Joerg ^b   Carbone, Emilio ^a  

^a NIS Centre of Excellence   (Italy)

^b Pharmacology and Toxicology   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; CALCIUM CHANNEL L TYPE; CATECHOLAMINE; DIHYDROPYRIDINE; EGTAZIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; NIFEDIPINE; PAXILLINE; VOLTAGE GATED CALCIUM CHANNEL;

ACTION POTENTIAL; AFTERHYPERPOLARIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CHANNELOPATHY; CELL STIMULATION; CHROMAFFIN CELL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME RELEASE; FREQUENCY MODULATION; MALE; MOUSE; NERVE CONDUCTION; NONHUMAN; PACEMAKER; PERCEPTIVE THRESHOLD; PRIORITY JOURNAL; SPIKE; WILD TYPE;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; ADRENAL CORTEX; ADRENAL MEDULLA; ANIMALS; BIOPHYSICAL PHENOMENA; BIOPHYSICS; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; CHELATING AGENTS; CHROMAFFIN CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; EGTAZIC ACID; ELECTRIC STIMULATION; GENE EXPRESSION REGULATION; INDOLES; IONOPHORES; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; SPIDER VENOMS; TIME FACTORS;

EID: 74949101892     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4961-09.2010     Document Type: Article

References (53)

1. Baldelli P, Hernández-Guijo JM, Carabelli V, Novara M, Cesetti T, Andrés-Mateos E, Montiel C, Carbone E (2004) Direct and remote modulation of L-channels in chromaffin cells: distinct actions on alpha1C and alpha1D subunits? Mol Neurobiol 29:73-96.
2. Bean BP (2007) The action potential in mammalian central neurons. Nat Rev Neurosci 8:451-465.
3. Brandt BL, Hagiwara S, Kidokoro Y, Miyazaki S (1976) Action potentials in the rat chromaffin cell and effects of acetylcholine. J Physiol 263:417-439.
4. Carabelli V, D'Ascenzo M, Carbone E, Grassi C (2002) Nitric oxide inhibits neuroendocrine Ca(V)1 L-channel gating via cGMP-dependent protein kinase in cell-attached patches of bovine chromaffin cells. J Physiol 541:351-366.
5. Carabelli V, Marcantoni A, Comunanza V, de Luca A, Díaz J, Borges R, Carbone E (2007) Chronic hypoxia up-regulates alpha1H T-type channels and low-threshold catecholamine secretion in rat chromaffin cells. J Physiol 584:149-165.
6. V1 L-channel current in rat adrenal chromaffin cells. J Neurosci 23:73-83.
7. Chan CS, Guzman JN, Ilijic E, Mercer JN, Rick C, Tkatch T, Meredith GE, Surmeier DJ (2007) "Rejuvenation" protects neurons in mouse models of Parkinson's disease. Nature 447:1081-1086.
8. Do MT, Bean BP (2003) Subthreshold sodium currents and pacemaking of subthalamic neurons: modulation by slow inactivation. Neuron 39: 109-120.
9. Duan K, Yu X, Zhang C, Zhou Z (2003) Control of secretion by temporal patterns of action potentials in adrenal chromaffin cells. J Neurosci 23: 11235-11243.
10. Fenwick EM, Marty A, Neher E (1982) A patch-clamp study of bovine chromaffin cells and of their sensitivity to acetylcholine. J Physiol 331: 577-597.
11. Fulop T, Radabaugh S, Smith C (2005) Activity-dependent differential transmitter release in mouse adrenal chromaffin cells. J Neurosci 25: 7324-7332.
12. 2+ channels, derived from mRNA identification studies. FEBS Lett 481:235-239.
13. + channel blockade enhances firing and epinephrine secretion in rat chromaffin cells: the missing link to LQT2-related sudden death? FASEB J 17:330-332.
14. Guzman JN, Sánchez-Padilla J, Chan CS, Surmeier DJ (2009) Robust pacemaking in substantia nigra dopaminergic neurons. J Neurosci 29:11011-11019.
15. Helton TD, Xu W, Lipscombe D (2005) Neuronal L-type calcium channels open quickly and are inhibited slowly. J Neurosci 25:10247-10251.
16. Hernández-Guijo JM, de Pascual R, García AG, Gandía L (1998) Separation of calcium channel current components in mouse chromaffin cells superfused with low- and high-barium solutions. Pflugers Arch 436:75-82.
17. Hernández-Guijo JM, Carabelli V, Gandía L, García AG, Carbone E (1999) Voltage-independent autocrine modulation of L-type channels mediated by ATP, opioids and catecholamines in rat chromaffin cells. Eur J Neurosci 11:3574-3584.
18. + current during mAChR activation in rat adrenal chromaffin cells. J Physiol 485:297-318.
19. Jackson AC, Yao GL, Bean BP (2004) Mechanism of spontaneous firing in dorsomedial suprachiasmatic nucleus neurons. J Neurosci 24:7985-7998.
20. 2+ channels activating at negative voltages. J Biol Chem 276:22100-22106.
21. 2+-dependent inactivation. J Neurosci 23:6041-6049.
22. Lipscombe D, Helton TD, Xu W (2004) L-type calcium channels: the low down. J Neurophysiol 92:2633-2641.
23. Magistretti J, Mantegazza M, Guatteo E, Wanke E (1996) Action potentials recorded with patch-clamp amplifiers: are they genuine? Trends Neurosci 19:530-534.
24. Mangoni ME, Nargeot J (2008) Genesis and regulation of the heart automaticity. Physiol Rev 88:919-982.
25. 2+ channels in cardiac pacemaker activity. Proc Natl Acad Sci U S A 100:5543-5548.
26. Marcantoni A, Baldelli P, Hernandez-Guijo JM, Comunanza V, Carabelli V, Carbone E (2007) L-type calcium channels in adrenal chromaffin cells: role in pace-making and secretion. Cell Calcium 42:397-408.
27. 2+ currents, action potential firing, and quantal size of exocytosis in mouse chromaffin cells. Pflugers Arch 457:1093-1110.
28. Nassar-Gentina V, Pollard HB, Rojas E (1988) Electrical activity in chromaffin cells of intact mouse adrenal gland. Am J Physiol 254:C675-C683.
29. Neely A, Lingle CJ (1992) Two components of calcium-activated potassium current in rat adrenal chromaffin cells. J Physiol 453:97-131.
30. Nelson AB, Krispel CM, Sekirnjak C, du Lac S (2003) Long-lasting increases in intrinsic excitability triggered by inhibition. Neuron 40:609-620.
31. 2+ channels is dependent on a shank-binding domain. J Neurosci 25:1050-1062.
32. 2+ channels. Brain Res Rev 40:223-229.
33. 2+ channels. Cell 102:89-97.
34. 2+ channels in rat chromaffin cells. J Neurophysiol 81:2267-2278.
35. 2+ channels. J Neurophysiol 84:1123-1135.
36. 2+ from intracellular stores in rat chromaffin cells. J Neurosci 16:4344-4359.
37. Puopolo M, Raviola E, Bean BP (2007) Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons. J Neurosci 27:645-656.
38. Raman IM, Bean BP (1999) Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons. J Neurosci 19:1663-1674.
39. Sanchez M, McManus OB (1996) Paxilline inhibition of the alpha-subunit of the high-conductance calcium-activated potassium channel. Neuropharmacology 35:963-968.
40. a2+-dependent gating of Cav1.3 L-type calcium channels by alternative splicing of a C-terminal regulatory domain. J Biol Chem 283:20733-20744.
41. Sinnegger-Brauns MJ, Huber IG, Koschak A, Wild C, Obermair GJ, Einzinger U, Hoda JC, Sartori SB, Striessnig J (2009) Expression and 1,4-dihydropyridine- binding properties of brain L-type calcium channel isoforms. Mol Pharmacol 75:407-414.
42. Solaro CR, Lingle CJ (1992) Trypsin-sensitive, rapid inactivation of a calcium-activated potassium channel. Science 257:1694-1698.
43. + current in rat adrenal chromaffin cells. J Neurosci 15:6110-6123.
44. Sørensen JB, Nagy G, Varoqueaux F, Nehring RB, Brose N, Wilson MC, Neher E (2003) Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23. Cell 114:75-86.
45. 2+ channels with gene knockout models. Channels 2:233-251.
46. Sun L, Xiong Y, Zeng X, Wu Y, Pan N, Lingle CJ, Qu A, Ding J (2009) Differential regulation of action potentials by inactivating and noninactivating BK channels in rat adrenal chromaffin cells. Biophys J 97:1832-1842.
47. Swensen AM, Bean BP (2003) Ionic mechanisms of burst firing in dissociated Purkinje neurons. J Neurosci 23:9650-9663.
48. Taddese A, Bean BP (2002) Subthreshold sodium current from rapidly inactivating sodium channels drives spontaneous firing of tuberomammillary neurons. Neuron 33:587-600.
49. Wallace DJ, Chen C, Marley PD (2002) Histamine promotes excitability in bovine adrenal chromaffin cells by inhibiting an M-current. J Physiol 540:921-939.
50. 2+ channels. Circ Res 81:526-532.
51. 2+-activated, voltage-dependent BK currents: consequences of rapid inactivation by a novel βsubunit. J Neurosci 20:4890-4903.
52. Zhang XF, Gopalakrishnan M, Shieh CC (2003) Modulation of action potential firing by iberiotoxin and NS1619 in rat dorsal root ganglion neurons. Neuroscience 122:1003-1011.
53. Zhou Z, Misler S (1995) Action potential-induced quantal secretion of catecholamines from rat adrenal chromaffin cells. J Biol Chem 270:3498-3505.