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Volumn 47, Issue 1, 2012, Pages 177-182

Novel zebrafish model reveals a critical role for MAPK in lymphangiogenesis

Author keywords

Lymphangiogenesis; Lymphatic disorders; MEK inhibitor; Primary lymphedema; VEGF; VEGF receptors

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; VASCULOTROPIN RECEPTOR;

EID: 84855823543     PISSN: 00223468     EISSN: 15315037     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2011.10.035     Document Type: Article
Times cited : (8)

References (38)
  • 1
    • 77955510391 scopus 로고    scopus 로고
    • VEGF-mediated signal transduction in lymphatic endothelial cells
    • F. Bahram, and L. Claesson-Welsh VEGF-mediated signal transduction in lymphatic endothelial cells Pathophysiology 17 2010 253 261
    • (2010) Pathophysiology , vol.17 , pp. 253-261
    • Bahram, F.1    Claesson-Welsh, L.2
  • 3
    • 77957682470 scopus 로고    scopus 로고
    • Current views on the function of the lymphatic vasculature in health and disease
    • Y. Wang, and G. Oliver Current views on the function of the lymphatic vasculature in health and disease Genes Dev 24 2010 2115 2126
    • (2010) Genes Dev , vol.24 , pp. 2115-2126
    • Wang, Y.1    Oliver, G.2
  • 4
    • 34249689753 scopus 로고    scopus 로고
    • Molecular regulation of angiogenesis and lymphangiogenesis
    • DOI 10.1038/nrm2183, PII NRM2183
    • R.H. Adams, and K. Alitalo Molecular regulation of angiogenesis and lymphangiogenesis Nat Rev Mol Cell Biol 8 2007 464 478 (Pubitemid 46823443)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.6 , pp. 464-478
    • Adams, R.H.1    Alitalo, K.2
  • 5
    • 0035355472 scopus 로고    scopus 로고
    • A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-γ and DNA synthesis in vascular endothelial cells
    • DOI 10.1093/emboj/20.11.2768
    • T. Takahashi, S. Yamaguchi, and K. Chida A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells EMBO J 20 2001 2768 2778 (Pubitemid 32938560)
    • (2001) EMBO Journal , vol.20 , Issue.11 , pp. 2768-2778
    • Takahashi, T.1    Yamaguchi, S.2    Chida, K.3    Shibuya, M.4
  • 7
    • 69249212354 scopus 로고    scopus 로고
    • Zebrafish as a new animal model to study lymphangiogenesis
    • S. Isogai, J. Hitomi, and K. Yaniv Zebrafish as a new animal model to study lymphangiogenesis Anat Sci Int 84 2009 102 111
    • (2009) Anat Sci Int , vol.84 , pp. 102-111
    • Isogai, S.1    Hitomi, J.2    Yaniv, K.3
  • 11
    • 77950469880 scopus 로고    scopus 로고
    • The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells
    • R.S. Srinivasan, X. Geng, and Y. Yang The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells Genes Dev 24 2010 696 707
    • (2010) Genes Dev , vol.24 , pp. 696-707
    • Srinivasan, R.S.1    Geng, X.2    Yang, Y.3
  • 12
    • 77955982948 scopus 로고    scopus 로고
    • Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish
    • I. Geudens, R. Herpers, and K. Hermans Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish Arterioscler Thromb Vasc Biol 30 2010 1695 1702
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1695-1702
    • Geudens, I.1    Herpers, R.2    Hermans, K.3
  • 13
    • 70450195982 scopus 로고    scopus 로고
    • Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries
    • B.M. Hogan, R. Herpers, and M. Witte Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries Development 136 2009 4001 4009
    • (2009) Development , vol.136 , pp. 4001-4009
    • Hogan, B.M.1    Herpers, R.2    Witte, M.3
  • 15
    • 0036039827 scopus 로고    scopus 로고
    • In vivo imaging of embryonic vascular development using transgenic zebrafish
    • DOI 10.1006/dbio.2002.0711
    • N.D. Lawson, and B.M. Weinstein In vivo imaging of embryonic vascular development using transgenic zebrafish Dev Biol 248 2002 307 318 (Pubitemid 35002091)
    • (2002) Developmental Biology , vol.248 , Issue.2 , pp. 307-318
    • Lawson, N.D.1    Weinstein, B.M.2
  • 16
    • 0035865186 scopus 로고    scopus 로고
    • The vascular anatomy of the developing zebrafish: An atlas of embryonic and early larval development
    • DOI 10.1006/dbio.2000.9995
    • S. Isogai, M. Horiguchi, and B.M. Weinstein The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development Dev Biol 230 2001 278 301 (Pubitemid 32171423)
    • (2001) Developmental Biology , vol.230 , Issue.2 , pp. 278-301
    • Isogai, S.1    Horiguchi, M.2    Weinstein, B.M.3
  • 17
    • 0242628897 scopus 로고    scopus 로고
    • Angiogenic network formation in the developing vertebrate trunk
    • DOI 10.1242/dev.00733
    • S. Isogai, N.D. Lawson, and S. Torrealday Angiogenic network formation in the developing vertebrate trunk Development 130 2003 5281 5290 (Pubitemid 37369685)
    • (2003) Development , vol.130 , Issue.21 , pp. 5281-5290
    • Isogai, S.1    Lawson, N.D.2    Torrealday, S.3    Horiguchi, M.4    Weinstein, B.M.5
  • 20
    • 0242468891 scopus 로고    scopus 로고
    • CI-1040 (PD184352), a Targeted Signal Transduction Inhibitor of MEK (MAPKK)
    • L.F. Allen, J. Sebolt-Leopold, and M.B. Meyer CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK) Semin Oncol 30 2003 105 116 (Pubitemid 37433401)
    • (2003) Seminars in Oncology , vol.30 , Issue.5 SUPPL. 16 , pp. 105-116
    • Allen, L.F.1    Sebolt-Leopold, J.2    Meyer, M.B.3
  • 21
    • 15744380263 scopus 로고    scopus 로고
    • Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition
    • J.F. Ohren, H. Chen, and A. Pavlovsky Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition Nat Struct Mol Biol 11 2004 1192 1197
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 1192-1197
    • Ohren, J.F.1    Chen, H.2    Pavlovsky, A.3
  • 22
    • 78649962080 scopus 로고    scopus 로고
    • Constitutive MEK1 activation rescues anthrax lethal toxin-induced vascular effects in vivo
    • R.E. Bolcome III, and J. Chan Constitutive MEK1 activation rescues anthrax lethal toxin-induced vascular effects in vivo Infect Immun 78 2010 5043 5053
    • (2010) Infect Immun , vol.78 , pp. 5043-5053
    • Bolcome III, R.E.1    Chan, J.2
  • 24
    • 77957365795 scopus 로고    scopus 로고
    • Akt/protein kinase B is required for lymphatic network formation, remodeling, and valve development
    • F. Zhou, Z. Chang, and L. Zhang Akt/protein kinase B is required for lymphatic network formation, remodeling, and valve development Am J Pathol 2010
    • (2010) Am J Pathol
    • Zhou, F.1    Chang, Z.2    Zhang, L.3
  • 25
    • 53049087363 scopus 로고    scopus 로고
    • Effects of the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 on the tumor vasculature: Implications for clinical imaging
    • C.R. Schnell, F. Stauffer, and P.R. Allegrini Effects of the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 on the tumor vasculature: implications for clinical imaging Cancer Res 68 2008 6598 6607
    • (2008) Cancer Res , vol.68 , pp. 6598-6607
    • Schnell, C.R.1    Stauffer, F.2    Allegrini, P.R.3
  • 26
    • 51849111524 scopus 로고    scopus 로고
    • NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations
    • V. Serra, B. Markman, and M. Scaltriti NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations Cancer Res 68 2008 8022 8030
    • (2008) Cancer Res , vol.68 , pp. 8022-8030
    • Serra, V.1    Markman, B.2    Scaltriti, M.3
  • 28
    • 30744479430 scopus 로고    scopus 로고
    • Angiogenesis in life, disease and medicine
    • DOI 10.1038/nature04478, PII NATURE04478
    • P. Carmeliet Angiogenesis in life, disease and medicine Nature 438 2005 932 936 (Pubitemid 43093958)
    • (2005) Nature , vol.438 , Issue.7070 , pp. 932-936
    • Carmeliet, P.1
  • 29
    • 47949083776 scopus 로고    scopus 로고
    • Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos
    • P. Haiko, T. Makinen, and S. Keskitalo Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos Mol Cell Biol 8 2008 4843 4850
    • (2008) Mol Cell Biol , vol.8 , pp. 4843-4850
    • Haiko, P.1    Makinen, T.2    Keskitalo, S.3
  • 31
    • 67449132621 scopus 로고    scopus 로고
    • Recessive primary congenital lymphoedema caused by a VEGFR3 mutation
    • A. Ghalamkarpour, W. Holnthoner, and P. Saharinen Recessive primary congenital lymphoedema caused by a VEGFR3 mutation J Med Genet 2009
    • (2009) J Med Genet
    • Ghalamkarpour, A.1    Holnthoner, W.2    Saharinen, P.3
  • 32
    • 77951695913 scopus 로고    scopus 로고
    • Lymphatic dysfunction, not aplasia, underlies Milroy disease
    • R.H. Mellor, C.E. Hubert, and A.W. Stanton Lymphatic dysfunction, not aplasia, underlies Milroy disease Microcirculation 17 2010 281 296
    • (2010) Microcirculation , vol.17 , pp. 281-296
    • Mellor, R.H.1    Hubert, C.E.2    Stanton, A.W.3
  • 33
    • 77949855801 scopus 로고    scopus 로고
    • The role of lymphatic mapping and sentinel node biopsy in the management of atypical and anomalous melanocytic lesions
    • A.J. Cochran, S. Binder, and D.L. Morton The role of lymphatic mapping and sentinel node biopsy in the management of atypical and anomalous melanocytic lesions J Cutan Pathol 37 2010 54 59
    • (2010) J Cutan Pathol , vol.37 , pp. 54-59
    • Cochran, A.J.1    Binder, S.2    Morton, D.L.3
  • 34
    • 0036527350 scopus 로고    scopus 로고
    • Dissection of angiogenic signaling in zebrafish using a chemical genetic approach
    • DOI 10.1016/S1535-6108(02)00042-9
    • J. Chan, P.E. Bayliss, and J.M. Wood Dissection of angiogenic signaling in zebrafish using a chemical genetic approach Cancer Cell 1 2002 257 267 (Pubitemid 41039150)
    • (2002) Cancer Cell , vol.1 , Issue.3 , pp. 257-267
    • Chan, J.1    Bayliss, P.E.2    Wood, J.M.3    Roberts, T.M.4
  • 35
    • 33646455462 scopus 로고    scopus 로고
    • Chemical modulation of receptor signaling inhibits regenerative angiogenesis in adult zebrafish
    • P.E. Bayliss, K.L. Bellavance, and G.G. Whitehead Chemical modulation of receptor signaling inhibits regenerative angiogenesis in adult zebrafish Nat Chem Biol 2 2006 265 273
    • (2006) Nat Chem Biol , vol.2 , pp. 265-273
    • Bayliss, P.E.1    Bellavance, K.L.2    Whitehead, G.G.3
  • 38
    • 57349194139 scopus 로고    scopus 로고
    • Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
    • J.A. Engelman, L. Chen, and X. Tan Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers Nat Med 14 2008 1351 1356
    • (2008) Nat Med , vol.14 , pp. 1351-1356
    • Engelman, J.A.1    Chen, L.2    Tan, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.