-
1
-
-
59649092315
-
Immunopharmacotherapy: Vaccination strategies as a treatment for drug abuse and dependence
-
A.Y. Moreno, and K.D. Janda Immunopharmacotherapy: vaccination strategies as a treatment for drug abuse and dependence Pharmacol Biochem Behav 92 2009 199 205
-
(2009)
Pharmacol Biochem Behav
, vol.92
, pp. 199-205
-
-
Moreno, A.Y.1
Janda, K.D.2
-
2
-
-
84855776087
-
Immunotherapies to treat drug addiction
-
M.M. Levine, Dekker New York
-
P.R. Pentel, D.E. Keyler, and T.R. Kosten Immunotherapies to treat drug addiction M.M. Levine, New generation vaccines 2009 Dekker New York 982 992
-
(2009)
New Generation Vaccines
, pp. 982-992
-
-
Pentel, P.R.1
Keyler, D.E.2
Kosten, T.R.3
-
3
-
-
32844473670
-
Effects of a nicotine conjugate vaccine on the acquisition and maintenance of nicotine self-administration in rats
-
DOI 10.1007/s00213-005-0027-2
-
M.G. LeSage, D.E. Keyler, Y. Hieda, G. Collins, D. Burroughs, and C. Le Effects of a nicotine conjugate vaccine on the acquisition and maintenance of nicotine self-administration in rats Psychopharmacology (Berl) 184 2006 409 416 (Pubitemid 43255857)
-
(2006)
Psychopharmacology
, vol.184
, Issue.3-4
, pp. 409-416
-
-
LeSage, M.G.1
Keyler, D.E.2
Hieda, Y.3
Collins, G.4
Burroughs, D.5
Le, C.6
Pentel, P.R.7
-
4
-
-
70349504135
-
Vaccines against morphine/heroin and its use as effective medication for preventing relapse to opiate addictive behaviors
-
B. Anton, A. Salazar, A. Flores, M. Matus, R. Marin, and J.A. Hernandez Vaccines against morphine/heroin and its use as effective medication for preventing relapse to opiate addictive behaviors Hum Vaccin 5 2009 214 229
-
(2009)
Hum Vaccin
, vol.5
, pp. 214-229
-
-
Anton, B.1
Salazar, A.2
Flores, A.3
Matus, M.4
Marin, R.5
Hernandez, J.A.6
-
6
-
-
79951813724
-
Immunogenicity and smoking-cessation outcomes for a novel nicotine immunotherapeutic
-
D.K. Hatsukami, D.E. Jorenby, D. Gonzales, N.A. Rigotti, E.D. Glover, and C.A. Oncken Immunogenicity and smoking-cessation outcomes for a novel nicotine immunotherapeutic Clin Pharmacol Ther 89 2011 392 399
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 392-399
-
-
Hatsukami, D.K.1
Jorenby, D.E.2
Gonzales, D.3
Rigotti, N.A.4
Glover, E.D.5
Oncken, C.A.6
-
7
-
-
70349690285
-
Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: A randomized, double-blind, placebo-controlled efficacy trial
-
B.A. Martell, F.M. Orson, J. Poling, E. Mitchell, R.D. Rossen, and T. Gardner Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: a randomized, double-blind, placebo-controlled efficacy trial Arch Gen Psychiatry 66 2009 1116 1123
-
(2009)
Arch Gen Psychiatry
, vol.66
, pp. 1116-1123
-
-
Martell, B.A.1
Orson, F.M.2
Poling, J.3
Mitchell, E.4
Rossen, R.D.5
Gardner, T.6
-
8
-
-
84855815106
-
Interim analysis of an ongoing phase II study with nicotine vaccine shows primary endpoint not achieved
-
Interim analysis of an ongoing phase II study with nicotine vaccine shows primary endpoint not achieved. Cytos Biotechnology Press release; http://wwwcytoscom/defaultasp?id=1572: 2011.
-
(2011)
Cytos Biotechnology Press Release
-
-
-
9
-
-
0038789010
-
A new strategy for improved nicotine vaccines using conformationally constrained haptens
-
DOI 10.1021/ja034805t
-
M.M. Meijler, M. Matsushita, L.J. Altobell 3rd, P. Wirsching, and K.D. Janda A new strategy for improved nicotine vaccines using conformationally constrained haptens J Am Chem Soc 125 2003 7164 7165 (Pubitemid 36798951)
-
(2003)
Journal of the American Chemical Society
, vol.125
, Issue.24
, pp. 7164-7165
-
-
Meijler, M.M.1
Matsushita, M.2
Altobell III, L.J.3
Wirsching, P.4
Janda, K.D.5
-
10
-
-
70949094408
-
The synthesis of haptens and their use for the development of monoclonal antibodies for treating methamphetamine abuse
-
F.I. Carroll, P. Abraham, P.K. Gong, R.R. Pidaparthi, B.E. Blough, and Y. Che The synthesis of haptens and their use for the development of monoclonal antibodies for treating methamphetamine abuse J Med Chem 52 2009 7301 7309
-
(2009)
J Med Chem
, vol.52
, pp. 7301-7309
-
-
Carroll, F.I.1
Abraham, P.2
Gong, P.K.3
Pidaparthi, R.R.4
Blough, B.E.5
Che, Y.6
-
11
-
-
34250788109
-
Using hapten design to discover therapeutic monoclonal antibodies for treating methamphetamine abuse
-
DOI 10.1124/jpet.106.117150
-
E.C. Peterson, M. Gunnell, Y. Che, R.L. Goforth, F.I. Carroll, and R. Henry Using hapten design to discover therapeutic monoclonal antibodies for treating methamphetamine abuse J Pharmacol Exp Ther 322 2007 30 39 (Pubitemid 46956367)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.322
, Issue.1
, pp. 30-39
-
-
Peterson, E.C.1
Gunnell, M.2
Che, Y.3
Goforth, R.L.4
Carroll, F.I.5
Henry, R.6
Liu, H.7
Owens, S.M.8
-
12
-
-
0035874752
-
An immunotherapeutic program for the treatment of nicotine addiction: Hapten design and synthesis
-
DOI 10.1021/jo001442w
-
S. Isomura, P. Wirsching, and K.D. Janda An immunotherapeutic program for the treatment of nicotine addiction: hapten design and synthesis J Org Chem 66 2001 4115 4121 (Pubitemid 32867545)
-
(2001)
Journal of Organic Chemistry
, vol.66
, Issue.12
, pp. 4115-4121
-
-
Isomura, S.1
Wirsching, P.2
Janda, K.D.3
-
13
-
-
79960632723
-
Synthesis of mercapto-(+)-methamphetamine haptens and their use for obtaining improved epitope density on (+)-methamphetamine conjugate vaccines
-
F.I. Carroll, B.E. Blough, R.R. Pidaparthi, P. Abraham, P.K. Gong, and L. Deng Synthesis of mercapto-(+)-methamphetamine haptens and their use for obtaining improved epitope density on (+)-methamphetamine conjugate vaccines J Med Chem 54 2011 5221 5228
-
(2011)
J Med Chem
, vol.54
, pp. 5221-5228
-
-
Carroll, F.I.1
Blough, B.E.2
Pidaparthi, R.R.3
Abraham, P.4
Gong, P.K.5
Deng, L.6
-
14
-
-
79960649757
-
A vaccine strategy that induces protective immunity against heroin
-
G.N. Stowe, L.F. Vendruscolo, S. Edwards, J.E. Schlosburg, K.K. Misra, and G. Schulteis A vaccine strategy that induces protective immunity against heroin J Med Chem 54 2011 5195 5204
-
(2011)
J Med Chem
, vol.54
, pp. 5195-5204
-
-
Stowe, G.N.1
Vendruscolo, L.F.2
Edwards, S.3
Schlosburg, J.E.4
Misra, K.K.5
Schulteis, G.6
-
15
-
-
22544431937
-
A therapeutic vaccine for nicotine dependence: Preclinical efficacy, and phase I safety and immunogenicity
-
DOI 10.1002/eji.200526285
-
P. Maurer, G.T. Jennings, J. Willers, F. Rohner, Y. Lindman, and K. Roubicek A therapeutic vaccine for nicotine dependence: preclinical efficacy, and phase I safety and immunogenicity Eur J Immunol 35 2005 2031 2040 (Pubitemid 41015042)
-
(2005)
European Journal of Immunology
, vol.35
, Issue.7
, pp. 2031-2040
-
-
Maurer, P.1
Jennings, G.T.2
Willers, J.3
Rohner, F.4
Lindman, Y.5
Roubicek, K.6
Renner, W.A.7
Muller, P.8
Bachmann, M.F.9
-
16
-
-
67349098393
-
Immune responses to methamphetamine by active immunization with peptide-based, molecular adjuvant-containing vaccines
-
M.J. Duryee, R.A. Bevins, C.M. Reichel, J.E. Murray, Y. Dong, and G.M. Thiele Immune responses to methamphetamine by active immunization with peptide-based, molecular adjuvant-containing vaccines Vaccine 27 2009 2981 2988
-
(2009)
Vaccine
, vol.27
, pp. 2981-2988
-
-
Duryee, M.J.1
Bevins, R.A.2
Reichel, C.M.3
Murray, J.E.4
Dong, Y.5
Thiele, G.M.6
-
17
-
-
51749104142
-
Enhanced immunogenicity of a bivalent nicotine vaccine
-
D.E. Keyler, S.A. Roiko, C.A. Earley, M.P. Murtaugh, and P.R. Pentel Enhanced immunogenicity of a bivalent nicotine vaccine Int Immunopharmacol 8 2008 1589 1594
-
(2008)
Int Immunopharmacol
, vol.8
, pp. 1589-1594
-
-
Keyler, D.E.1
Roiko, S.A.2
Earley, C.A.3
Murtaugh, M.P.4
Pentel, P.R.5
-
18
-
-
0002641023
-
Organic sulfur compounds. III. Synthesis of 2-(substituted alkylamine)ethanethiols
-
F.I. Carroll, H.M. Dickson, and M.E. Wall Organic sulfur compounds. III. Synthesis of 2-(substituted alkylamine)ethanethiols J Org Chem 30 1965 33 38
-
(1965)
J Org Chem
, vol.30
, pp. 33-38
-
-
Carroll, F.I.1
Dickson, H.M.2
Wall, M.E.3
-
19
-
-
0033957739
-
A nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates its behavioral and cardiovascular effects in rats
-
DOI 10.1016/S0091-3057(99)00206-3, PII S0091305799002063
-
P.R. Pentel, D.H. Malin, S. Ennifar, Y. Hieda, D.E. Keyler, and J.R. Lake A nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates its behavioral and cardiovascular effects in rats Pharmacol Biochem Behav 65 2000 191 198 (Pubitemid 30018012)
-
(2000)
Pharmacology Biochemistry and Behavior
, vol.65
, Issue.1
, pp. 191-198
-
-
Pentel, P.R.1
Malin, D.H.2
Ennifar, S.3
Hieda, Y.4
Keyler, D.E.5
Lake, J.R.6
Milstein, J.R.7
Basham, L.E.8
Coy, R.T.9
Moon, J.W.D.10
Naso, R.11
Fattom, A.12
-
20
-
-
0031470566
-
Active immunization alters the plasma nicotine concentration in rats
-
Y. Hieda, D.E. Keyler, J.T. Vandevoort, J.K. Kane, C.A. Ross, and D.E. Raphael Active immunization alters the plasma nicotine concentration in rats J Pharmacol Exp Ther 283 1997 1076 1081 (Pubitemid 28016479)
-
(1997)
Journal of Pharmacology and Experimental Therapeutics
, vol.283
, Issue.3
, pp. 1076-1081
-
-
Hieda, Y.1
Keyler, D.E.2
Vandevoort, J.T.3
Kane, J.K.4
Ross, C.A.5
Raphael, D.E.6
Niedbalas, R.S.7
Pentel, P.R.8
-
21
-
-
0020971366
-
Determination of affinity and specificity of anti-hapten antibodies by competitive radioimmunoassay
-
R. Muller Determination of affinity and specificity of anti-hapten antibodies by competitive radioimmunoassay Methods Enzymol 92 1983 589 601 (Pubitemid 14004096)
-
(1983)
Methods in Enzymology
, vol.92
, pp. 589-601
-
-
Muller, R.1
-
22
-
-
0026152241
-
Selected ion monitoring method for determination of nicotine, cotinine and deuterium-labeled analogs: Absence of an isotope effect in the clearance of (S)-nicotine-3′,3′-d2 in humans
-
P. Jacob, L. Yu, M. Wilson, and N.L. Benowitz Selected ion monitoring method for determination of nicotine, cotinine and deuterium-labeled analogs: absence of an isotope effect in the clearance of (S)-nicotine-3′,3′- d2 in humans Biol Mass Spectrom 20 1991 247 252
-
(1991)
Biol Mass Spectrom
, vol.20
, pp. 247-252
-
-
Jacob, P.1
Yu, L.2
Wilson, M.3
Benowitz, N.L.4
-
23
-
-
0012692555
-
Immunization of rats reduces nicotine distribution to brain
-
DOI 10.1007/s002130050930
-
Y. Hieda, D.E. Keyler, J.T. VanDeVoort, R.S. Niedbala, D.E. Raphael, and C.A. Ross Immunization of rats reduces nicotine distribution to brain Psychopharmacology 143 1999 150 157 (Pubitemid 29187639)
-
(1999)
Psychopharmacology
, vol.143
, Issue.2
, pp. 150-157
-
-
Hieda, Y.1
Keyler, D.E.2
VanDeVoort, J.T.3
Niedbala, R.S.4
Raphael, D.E.5
Ross, C.A.6
Pentel, P.R.7
-
24
-
-
84855804949
-
Rationalizing childhood immunization programs: The variation in schedules and use of combination vaccines
-
M.M. Levine, G. Dougan, M.F. Good, M.A. Liu, G.J. Nabel, J.P. Nataro, Informa Healthcare New York
-
A.J. Pollard, K.M. Edwards, and k. Fritzell Rationalizing childhood immunization programs: the variation in schedules and use of combination vaccines M.M. Levine, G. Dougan, M.F. Good, M.A. Liu, G.J. Nabel, J.P. Nataro, New generation vaccines 2010 Informa Healthcare New York 430 442
-
(2010)
New Generation Vaccines
, pp. 430-442
-
-
Pollard, A.J.1
Edwards, K.M.2
Fritzell, K.3
-
25
-
-
0036976430
-
Preclinical development of a vaccine 'against smoking'
-
DOI 10.1159/000067433
-
E.H. Cerny, R. Levy, J. Mauel, M. Mpandi, M. Mutter, and C. Henzelin-Nkubana Preclinical development of a vaccine 'Against Smoking' Onkologie 25 2002 406 411 (Pubitemid 36160178)
-
(2002)
Onkologie
, vol.25
, Issue.5
, pp. 406-411
-
-
Cerny, E.H.1
Levy, R.2
Mauel, J.3
Mpandi, M.4
Mutter, M.5
Henzelin-Nkubana, C.6
Patiny, L.7
Tuchscherer, G.8
Cerny, T.9
-
26
-
-
0346500730
-
Investigations using immunization to attenuate the psychoactive effects of nicotine
-
DOI 10.1016/j.bmc.2003.11.029
-
M.R. Carrera, J.A. Ashley, T.Z. Hoffman, S. Isomura, P. Wirsching, and G.F. Koob Investigations using immunization to attenuate the psychoactive effects of nicotine Bioorg Med Chem 12 2004 563 570 (Pubitemid 38102225)
-
(2004)
Bioorganic and Medicinal Chemistry
, vol.12
, Issue.3
, pp. 563-570
-
-
Carrera, M.R.A.1
Ashley, J.A.2
Hoffman, T.Z.3
Isomura, S.4
Wirsching, P.5
Koob, G.F.6
Janda, K.D.7
-
27
-
-
77049121986
-
Nicotine hapten structure, antibody selectivity and effect relationships: Results from a nicotine vaccine screening procedure
-
S.H. de Villiers, N. Lindblom, G. Kalayanov, S. Gordon, I. Baraznenok, and A. Malmerfelt Nicotine hapten structure, antibody selectivity and effect relationships: results from a nicotine vaccine screening procedure Vaccine 28 2010 2161 2168
-
(2010)
Vaccine
, vol.28
, pp. 2161-2168
-
-
De Villiers, S.H.1
Lindblom, N.2
Kalayanov, G.3
Gordon, S.4
Baraznenok, I.5
Malmerfelt, A.6
-
28
-
-
0037238710
-
Immunization to nicotine with a peptide-based vaccine composed of a conformationally biased agonist of C5a as a molecular adjuvant
-
DOI 10.1016/S1567-5769(02)00260-6, PII S1567576902002606
-
S.D. Sanderson, S.R. Cheruku, M.P. Padmanilayam, J.L. Vennerstrom, G.M. Thiele, and M.I. Palmatier Immunization to nicotine with a peptide-based vaccine composed of a conformationally biased agonist of C5a as a molecular adjuvant Int Immunopharmacol 3 2003 137 146 (Pubitemid 36106459)
-
(2003)
International Immunopharmacology
, vol.3
, Issue.1
, pp. 137-146
-
-
Sanderson, S.D.1
Cheruku, S.R.2
Padmanilayam, M.P.3
Vennerstrom, J.L.4
Thiele, G.M.5
Palmatier, M.I.6
Bevins, R.A.7
-
29
-
-
33846672181
-
Epitope mapping using combinatorial phage-display libraries: A graph-based algorithm
-
DOI 10.1093/nar/gkl975
-
I. Mayrose, T. Shlomi, N.D. Rubinstein, J.M. Gershoni, E. Ruppin, and R. Sharan Epitope mapping using combinatorial phage-display libraries: a graph-based algorithm Nucleic Acids Res 35 2007 69 78 (Pubitemid 46189832)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.1
, pp. 69-78
-
-
Mayrose, I.1
Shlomi, T.2
Rubinstein, N.D.3
Gershoni, J.M.4
Ruppin, E.5
Sharan, R.6
Pupko, T.7
-
30
-
-
44249119389
-
Combined active and passive immunization enhances the efficacy of immunotherapy against nicotine in rats
-
DOI 10.1124/jpet.107.135111
-
S.A. Roiko, A.C. Harris, D.E. Keyler, M.G. Lesage, Y. Zhang, and P.R. Pentel Combined active and passive immunization enhances the efficacy of immunotherapy against nicotine in rats J Pharmacol Exp Ther 325 2008 985 993 (Pubitemid 351724343)
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.325
, Issue.3
, pp. 985-993
-
-
Roiko, S.A.1
Harris, A.C.2
Keyler, D.E.3
LeSage, M.G.4
Zhang, Y.5
Pentel, P.R.6
-
31
-
-
79955399425
-
Impact of distinct chemical structures for the development of a methamphetamine vaccine
-
A.Y. Moreno, A.V. Mayorov, and K.D. Janda Impact of distinct chemical structures for the development of a methamphetamine vaccine J Am Chem Soc 133 2011 6587 6595
-
(2011)
J Am Chem Soc
, vol.133
, pp. 6587-6595
-
-
Moreno, A.Y.1
Mayorov, A.V.2
Janda, K.D.3
-
32
-
-
0032867637
-
Nornicotine is self-administered intravenously by rats
-
DOI 10.1007/s002130051119
-
M.T. Bardo, T.A. Green, P.A. Crooks, and L.P. Dwoskin Nornicotine is self-administered intravenously by rats Psychopharmacology 146 1999 290 296 (Pubitemid 29480240)
-
(1999)
Psychopharmacology
, vol.146
, Issue.3
, pp. 290-296
-
-
Bardo, M.T.1
Green, T.A.2
Crooks, P.A.3
Dwoskin, L.P.4
|