Relationships between acylated ghrelin with growth hormone, insulin resistance, lipid profile, and cardio respiratory function in lean and obese men

Journal of Research in Medical Sciences

Volumn 16, Issue 12, 2011, Pages 1612-1618

  Homaee, Hasan Matin ^a   Moradi, Fatah ^a   Azarbayjani, Mohammad Ali ^a   Peeri, Maghsoud ^a  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Adipose; Gherlin; Insulin resistance index; Obesity; VO 2max

Indexed keywords

ACYLATED GHRELIN; GHRELIN; GLUCOSE; GROWTH HORMONE; INSULIN; LIPID; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BODY FAT; BODY MASS; BODY WEIGHT; CARDIOPULMONARY FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; GLUCOSE BLOOD LEVEL; HOMEOSTASIS MODEL ASSESSMENT OF INSULIN RESISTANCE; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MALE; OBESITY; OXYGEN CONSUMPTION; PHYSICAL ACTIVITY; SYSTOLIC BLOOD PRESSURE;

EID: 84855791266     PISSN: 17351995     EISSN: 17357136     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Marzullo P, Verti B, Savia G, Walker GE, Guzzaloni G, Tagliaferri M, et al. The relationship between active ghrelin levels and human obesity involves alterations in resting energy expenditure. J Clin Endocrinol Metab 2004; 89(2): 936-9.
2. Ariyasu H, Takaya K, Tagami T, Ogawa Y, Hosoda K, Akamizu T, et al. Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. J Clin Endocrinol Metab 2001; 86(10): 4753-8.
3. Otto B, Cuntz U, Fruehauf E, Wawarta R, Folwaczny C, Riepl RL, et al. Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa. Eur J Endocrinol 2001; 145(5): 669-73.
4. Otto B, Tschop M, Heldwein W, Pfeiffer AF, Diederich S. Endogenous and exogenous glucocorticoids decrease plasma ghrelin in humans. Eur J Endocrinol 2004; 151(1): 113-7.
5. Robertson MD, Henderson RA, Vist GE, Rumsey RD. Plasma ghrelin response following a period of acute overfeeding in normal weight men. Int J Obes Relat Metab Disord 2004; 28(6): 727-33.
6. Choi K, Roh SG, Hong YH, Shrestha YB, Hishikawa D, Chen C, et al. The role of ghrelin and growth hormone secretagogues receptor on rat adipogenesis. Endocrinology 2003; 144(3): 754-9.
7. Tang-Christensen M, Vrang N, Ortmann S, Bidlingmaier M, Horvath TL, Tschop M. Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats. Endocrinology 2004; 145(10): 4645-52.
8. Overduin J, Frayo RS, Grill HJ, Kaplan JM, Cummings DE. Role of the duodenum and macronutrient type in ghrelin regulation. Endocrinology 2005; 146(2): 845-50.
9. Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE, Weigle DS. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 2001; 50(8): 1714-9.
10. Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, et al. Plasma ghrelin levels after dietinduced weight loss or gastric bypass surgery. N Engl J Med 2002; 346(21): 1623-30.
11. Grinspoon S, Miller KK, Herzog DB, Grieco KA, Klibanski A. Effects of estrogen and recombinant human insulinlike growth factor-I on ghrelin secretion in severe undernutrition. J Clin Endocrinol Metab 2004; 89(8): 3988-93.
12. Anderwald C, Brabant G, Bernroider E, Horn R, Brehm A, Waldhausl W, et al. Insulin-dependent modulation of plasma ghrelin and leptin concentrations is less pronounced in type 2 diabetic patients. Diabetes 2003; 52(7): 1792-8.
13. Mohlig M, Spranger J, Otto B, Ristow M, Tschop M, Pfeiffer AF. Euglycemic hyperinsulinemia, but not lipid infusion, decreases circulating ghrelin levels in humans. J Endocrinol Invest 2002; 25(11): RC36-RC38.
14. Arafat MA, Otto B, Rochlitz H, Tschop M, Bahr V, Mohlig M, et al. Glucagon inhibits ghrelin secretion in humans. Eur J Endocrinol 2005; 153(3): 397-402.
15. Natalucci G, Riedl S, Gleiss A, Zidek T, Frisch H. Spontaneous 24-h ghrelin secretion pattern in fasting subjects: maintenance of a meal-related pattern. Eur J Endocrinol 2005; 152(6): 845-50.
16. Broglio F, Arvat E, Benso A, Gottero C, Muccioli G, Papotti M, et al. Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans. J Clin Endocrinol Metab 2001; 86(10): 5083-6.
17. Egido EM, Rodriguez-Gallardo J, Silvestre RA, Marco J. Inhibitory effect of ghrelin on insulin and pancreatic somatostatin secretion. Eur J Endocrinol 2002; 146(2): 241-4.
18. Date Y, Nakazato M, Hashiguchi S, Dezaki K, Mondal MS, Hosoda H, et al. Ghrelin is present in pancreatic alphacells of humans and rats and stimulates insulin secretion. Diabetes 2002; 51(1): 124-9.
19. Shiiya T, Nakazato M, Mizuta M, Date Y, Mondal MS, Tanaka M, et al. Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab 2002; 87(1): 240-4.
20. Kraemer RR, Castracane VD. Exercise and humoral mediators of peripheral energy balance: ghrelin and adiponectin. Exp Biol Med (Maywood) 2007; 232(2): 184-94.
21. Jackson AS, Pollock ML. Generalized equations for predicting body density of men. Br J Nutr 1978; 40(3): 497-504.
22. Siri WE. Body composition from fluid spaces and density: analysis of methods. 1961. Nutrition 1993; 9(5): 480-91.
23. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28(7): 412-9.
24. Cink RE, Thomas TR. Validity of the Astrand-Ryhming nomogram for predicting maximal oxygen intake. Br J Sports Med 1981; 15(3): 182-5.
25. English PJ, Ghatei MA, Malik IA, Bloom SR, Wilding JP. Food fails to suppress ghrelin levels in obese humans. J Clin Endocrinol Metab 2002; 87(6): 2984.
26. Yildiz BO, Suchard MA, Wong ML, McCann SM, Licinio J. Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity. Proc Natl Acad Sci U S A 2004; 101(28): 10434-9.
27. Scacchi M, Pincelli AI, Cavagnini F. Growth hormone in obesity. Int J Obes Relat Metab Disord 1999; 23(3): 260-71.
28. Benatti FB, Junior AH. Leptin and endurance exrcise: implications of adiposity and insulin. Rev Bras Med Esporte 2007; 13(4): 239E-44E.
29. Castaneda TR, Jurgens H, Wiedmer P, Pfluger P, Diano S, Horvath TL, et al. Obesity and the neuroendocrine control of energy homeostasis: the role of spontaneous locomotor activity. J Nutr 2005; 135(5): 1314-9.
30. Tolle V, Kadem M, Bluet-Pajot MT, Frere D, Foulon C, Bossu C, et al. Balance in ghrelin and leptin plasma levels in anorexia nervosa patients and constitutionally thin women. J Clin Endocrinol Metab 2003; 88(1): 109-16.
31. Leidy HJ, Gardner JK, Frye BR, Snook ML, Schuchert MK, Richard EL, et al. Circulating ghrelin is sensitive to changes in body weight during a diet and exercise program in normal-weight young women. J Clin Endocrinol Metab 2004; 89(6): 2659-64.
32. Tritos NA, Kokkotou EG. The physiology and potential clinical applications of ghrelin, a novel peptide hormone. Mayo Clin Proc 2006; 81(5): 653-60.
33. Tschop M, Weyer C, Tataranni PA, Devanarayan V, Ravussin E, Heiman ML. Circulating ghrelin levels are decreased in human obesity. Diabetes 2001; 50(4): 707-9.
34. Saad MF, Bernaba B, Hwu CM, Jinagouda S, Fahmi S, Kogosov E, et al. Insulin regulates plasma ghrelin concentration. J Clin Endocrinol Metab 2002; 87(8): 3997-4000.
35. Najafian J, Toghianifar N, Mohammadifard N, Nouri F. Association between sleep duration and metabolic syndrome in a population-based study: Isfahan Healthy Heart Program. J Res Med Sci 2011; 16(6): 801-6.
36. Azadbakht L, Esmaillzadeh A. Soy and cardio-metabolic abnormalities: an update. J Res Med Sci 2008; 13(2): 88-96.
37. Choi KM, Lee J, Lee KW, Seo JA, Oh JH, Kim SG, et al. The associations between plasma adiponectin, ghrelin levels and cardiovascular risk factors. Eur J Endocrinol 2004; 150(5): 715-8.