메뉴 건너뛰기




Volumn 30, Issue 4-6, 2011, Pages 291-305

Immunostimulatory activity of fucoidan from the brown alga Fucus evanescens: Role of sulfates and acetates

Author keywords

Cytokines; Dendritic cells; Fucoidans; Fucus evanescens; Immunomodulation; Polysaccharides

Indexed keywords

FUCUS; FUCUS EVANESCENS; MURINAE; PHAEOPHYCEAE;

EID: 84855790385     PISSN: 07328303     EISSN: 15322327     Source Type: Journal    
DOI: 10.1080/07328303.2011.604456     Document Type: Article
Times cited : (40)

References (56)
  • 1
    • 0038618955 scopus 로고    scopus 로고
    • Sulfated fucans, fresh perspectives: Structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide
    • DOI 10.1093/glycob/cwg058
    • Berteau, O.; Mulloy, B. Sulfated fucans, fresh perspectives: structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide. Glycobiology 2003, 13, 29R-40R. (Pubitemid 36665414)
    • (2003) Glycobiology , vol.13 , Issue.6
    • Berteau, O.1    Mulloy, B.2
  • 2
    • 58549097653 scopus 로고    scopus 로고
    • Fucoidans and fucoidanases-focus on techniques for molecular structure elucidation and modification of marine polysaccharides
    • Holtkamp, A. D.; Kelly, S.; Ulber, R.; Lang, S. Fucoidans and fucoidanases-focus on techniques for molecular structure elucidation and modification of marine polysaccharides. Appl. Microbiol. Biotechnol. 2009, 82, 1-11.
    • (2009) Appl. Microbiol. Biotechnol. , vol.82 , pp. 1-11
    • Holtkamp, A.D.1    Kelly, S.2    Ulber, R.3    Lang, S.4
  • 3
    • 34247556420 scopus 로고    scopus 로고
    • Synthesis and medical applications of oligosaccharides
    • DOI 10.1038/nature05819, PII NATURE05819
    • Seeberger, P. H.; Werz, D. B. Synthesis and medical applications of oligosaccharides. Nature 2007, 446, 1046-1051. (Pubitemid 46676067)
    • (2007) Nature , vol.446 , Issue.7139 , pp. 1046-1051
    • Seeberger, P.H.1    Werz, D.B.2
  • 4
    • 68249116079 scopus 로고    scopus 로고
    • From carbohydrate leads to glycomimetic drugs
    • Ernst, B.; Magnani, J. L. From carbohydrate leads to glycomimetic drugs. Nat. Rev. Drug Discov. 2009, 8, 661-677.
    • (2009) Nat. Rev. Drug Discov. , vol.8 , pp. 661-677
    • Ernst, B.1    Magnani, J.L.2
  • 6
    • 50949098274 scopus 로고    scopus 로고
    • Fucoidan: Structure and bioactivity
    • Basel, Switzerland
    • Li, B.; Lu, F.; Wei, X.; Zhao, R. Fucoidan: structure and bioactivity. Molecules (Basel, Switzerland) 2008, 13, 1671-1695.
    • (2008) Molecules , vol.13 , pp. 1671-1695
    • Li, B.1    Lu, F.2    Wei, X.3    Zhao, R.4
  • 7
    • 0342547019 scopus 로고    scopus 로고
    • Anticoagulant fucoidan fractions from Fucus vesiculosus induce platelet activation in vitro
    • DOI 10.1016/S0049-3848(97)00037-6, PII S0049384897000376
    • Dürig, J.; Bruhn, T.; Zurborn, K. H.; Gutensohn, K.; Bruhn, H. D.; Beress, L. Anticoagulant fucoidan fractions from Fucus vesiculosus induce platelet activation in vitro. Thromb. Res. 1997, 85, 479-491. (Pubitemid 27209939)
    • (1997) Thrombosis Research , vol.85 , Issue.6 , pp. 479-491
    • Durig, J.1    Bruhn, T.2    Zurborn, K.-H.3    Gutensohn, K.4    Bruhn, H.D.5    Beress, L.6
  • 8
    • 0033811059 scopus 로고    scopus 로고
    • The polysaccharide fucoidan inhibits microvascular thrombus formation independently from P-and L-selectin function in vivo
    • Thorlacius, H.; Vollmar, B.; Seyfert, U. T.; Vestweber, D.; Menger, M. D. The polysaccharide fucoidan inhibits microvascular thrombus formation independently from P-and L-selectin function in vivo. Eur. J. Clin. Invest. 2000, 30, 804-810.
    • (2000) Eur. J. Clin. Invest. , vol.30 , pp. 804-810
    • Thorlacius, H.1    Vollmar, B.2    Seyfert, U.T.3    Vestweber, D.4    Menger, M.D.5
  • 9
    • 0026572349 scopus 로고
    • Fibrinolytic and anticoagulant activities of highly sulfated fucoidan
    • Soeda, S.; Sakaguchi, S.; Shimeno, H.; Nagamatsu, A. Fibrinolytic and anticoagulant activities of highly sulfated fucoidan. Biochem. Pharmacol. 1992, 43, 1853-1858.
    • (1992) Biochem. Pharmacol. , vol.43 , pp. 1853-1858
    • Soeda, S.1    Sakaguchi, S.2    Shimeno, H.3    Nagamatsu, A.4
  • 12
    • 37849012013 scopus 로고    scopus 로고
    • Immunostimulatory effects of fucoidan on bone marrowderived dendritic cells
    • Kim, M. H.; Joo, H. G. Immunostimulatory effects of fucoidan on bone marrowderived dendritic cells. Immunol. Lett. 2008, 115, 138-143.
    • (2008) Immunol. Lett. , vol.115 , pp. 138-143
    • Kim, M.H.1    Joo, H.G.2
  • 17
    • 33748990299 scopus 로고    scopus 로고
    • Fucosphere - New microsphere carriers for peptide and protein delivery: Preparation and in vitro characterization
    • DOI 10.1080/02652040600687563, PII L772G326RV71G803
    • Sezer, A. D.; Akbuga, J. Fucosphere-new microsphere carriers for peptide and protein delivery: preparation and in vitro characterization. J. Microencapsul. 2006, 23, 513-522. (Pubitemid 44446593)
    • (2006) Journal of Microencapsulation , vol.23 , Issue.5 , pp. 513-522
    • Sezer, A.D.1    Akbuga, J.2
  • 19
    • 0035064621 scopus 로고    scopus 로고
    • A novel antivirally active fucan sulfate derived from an edible brown alga, Sargassum horneri
    • DOI 10.1248/cpb.49.484
    • Preeprame, S.; Hayashi, K.; Lee, J. B.; Sankawa, U.; Hayashi, T. A novel antivirally active fucan sulfate derived from an edible brown alga, Sargassum horneri. Chem. Pharm. Bull. 2001, 49, 484-485. (Pubitemid 32367686)
    • (2001) Chemical and Pharmaceutical Bulletin , vol.49 , Issue.4 , pp. 484-485
    • Preeprame, S.1    Hayashi, K.2    Lee, J.-B.3    Sankawa, U.4    Hayashi, T.5
  • 20
    • 0024781518 scopus 로고
    • Mucilaginous substances from macroalgae: An overview
    • Evans, L. V. Mucilaginous substances from macroalgae: an overview. Symp. Soc. Exp. Biol. 1989, 43, 455-461.
    • (1989) Symp. Soc. Exp. Biol. , vol.43 , pp. 455-461
    • Evans, L.V.1
  • 21
    • 6544263765 scopus 로고    scopus 로고
    • Monthly changes in the content of fucans, their constituent sugars and sulphate in cultured Laminaria japonica
    • Honya, M.; Mori, H.; Anzai, M.; Araki, Y.; Nisizawa, K. Monthly changes in the content of fucans, their constituent sugars and sulphate in cultured Laminaria japonica. Hydrobiologia 1999, 398-399, 411-416. (Pubitemid 29490105)
    • (1999) Hydrobiologia , vol.398-399 , pp. 411-416
    • Honya, M.1    Mori, H.2    Anzai, M.3    Araki, Y.4    Nisizawa, K.5
  • 22
    • 77349098052 scopus 로고    scopus 로고
    • Monthly changes in the content and monosaccharide composition of fucoidan from Undaria pinnatifida (Laminariales, Phaeophyta)
    • Skriptsova, A.; Shevchenko, N.; Zvyagintseva, T.; Imbs, T. Monthly changes in the content and monosaccharide composition of fucoidan from Undaria pinnatifida (Laminariales, Phaeophyta). J. Appl. Phycol. 2010, 22, 79-86.
    • (2010) J. Appl. Phycol. , vol.22 , pp. 79-86
    • Skriptsova, A.1    Shevchenko, N.2    Zvyagintseva, T.3    Imbs, T.4
  • 24
    • 54949096524 scopus 로고    scopus 로고
    • Effects of molecular weight and hydrolysis conditions on anticancer activity of fucoidans from sporophyll of Undaria pinnatifida
    • Yang, C.; Chung, D.; Shin, I. S.; Lee, H.; Kim, J.; Lee, Y.; You, S. Effects of molecular weight and hydrolysis conditions on anticancer activity of fucoidans from sporophyll of Undaria pinnatifida. Int. J. Biol. Macromol. 2008, 43, 433-437.
    • (2008) Int. J. Biol. Macromol. , vol.43 , pp. 433-437
    • Yang, C.1    Chung, D.2    Shin, I.S.3    Lee, H.4    Kim, J.5    Lee, Y.6    You, S.7
  • 25
    • 0000414030 scopus 로고
    • Fractionation and analysis of fucans from brown algae
    • Mabeau, S.; Kloareg, B.; Joseleau, J. P. Fractionation and analysis of fucans from brown algae. Phytochemistry 1990, 29, 2441-2445.
    • (1990) Phytochemistry , vol.29 , pp. 2441-2445
    • Mabeau, S.1    Kloareg, B.2    Joseleau, J.P.3
  • 26
    • 0028763775 scopus 로고
    • Isolation and partial characterization of a novel amino sugar-containing fucan sulfate from commercial Fucus vesiculosus fucoidan
    • DOI 10.1016/S0008-6215(00)90980-7
    • Nishino, T.; Nishioka, C.; Ura, H.; Nagumo, T. Isolation and partial characterization of a novel amino sugar-containing fucan sulfate from commercial Fucus vesiculosus fucoidan. Carbohydr. Res. 1994, 255, 213-224. (Pubitemid 24084974)
    • (1994) Carbohydrate Research , vol.255 , pp. 213-224
    • Nishino, T.1    Nishioka, C.2    Ura, H.3    Nagumo, T.4
  • 28
    • 0000398974 scopus 로고
    • Determination of inorganic sulphate in studies on the enzymic and non-enzymic hydrolysis of carbohydrate and other sulphate esters
    • Dodgson, K. S. Determination of inorganic sulphate in studies on the enzymic and non-enzymic hydrolysis of carbohydrate and other sulphate esters. Biochemical J. 1961, 78, 312-319.
    • (1961) Biochemical J. , vol.78 , pp. 312-319
    • Dodgson, K.S.1
  • 29
    • 0023406022 scopus 로고
    • Assay of reducing sugars in the nanomole range with 2, 2'-bicinchoninate
    • Waffenschmidt, S.; Jaenicke, L. Assay of reducing sugars in the nanomole range with 2, 2'-bicinchoninate. Anal. Biochem. 1987, 165, 337-340.
    • (1987) Anal. Biochem. , vol.165 , pp. 337-340
    • Waffenschmidt, S.1    Jaenicke, L.2
  • 30
    • 0026481133 scopus 로고
    • Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
    • Inaba, K.; Inaba, M.; Romani, N.; Aya, H.; Deguchi, M.; Ikehara, S.; Muramatsu, S.; Steinman, R. M. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 1992, 176, 1693-1702.
    • (1992) J. Exp. Med. , vol.176 , pp. 1693-1702
    • Inaba, K.1    Inaba, M.2    Romani, N.3    Aya, H.4    Deguchi, M.5    Ikehara, S.6    Muramatsu, S.7    Steinman, R.M.8
  • 33
    • 63549122416 scopus 로고    scopus 로고
    • Structural analysis of a fucoidan from the brown alga Fucus evanescens by MALDI-TOF and tandem ESI mass spectrometry
    • Anastyuk, S. D.; Shevchenko, N. M.; Nazarenko, E. L.; Dmitrenok, P. S.; Zvyagintseva, T. N. Structural analysis of a fucoidan from the brown alga Fucus evanescens by MALDI-TOF and tandem ESI mass spectrometry. Carbohydr. Res. 2009, 344, 779-787.
    • (2009) Carbohydr. Res. , vol.344 , pp. 779-787
    • Anastyuk, S.D.1    Shevchenko, N.M.2    Nazarenko, E.L.3    Dmitrenok, P.S.4    Zvyagintseva, T.N.5
  • 34
    • 55249086579 scopus 로고    scopus 로고
    • Fucoidan stimulation induces a functional maturation of human monocyte-derived dendritic cells
    • Yang, M.; Ma, C.; Sun, J.; Shao, Q.; Gao, W.; Zhang, Y.; Li, Z.; Xie, Q.; Dong, Z.; Qu, X. Fucoidan stimulation induces a functional maturation of human monocyte-derived dendritic cells. Int. Immunopharmacol. 2008, 8, 1754-1760.
    • (2008) Int. Immunopharmacol. , vol.8 , pp. 1754-1760
    • Yang, M.1    Ma, C.2    Sun, J.3    Shao, Q.4    Gao, W.5    Zhang, Y.6    Li, Z.7    Xie, Q.8    Dong, Z.9    Qu, X.10
  • 35
    • 67651114081 scopus 로고    scopus 로고
    • Ligand of scavenger receptor class A indirectly induces maturation of human blood dendritic cells via production of tumor necrosis factor-alpha
    • Jin, J. O.; Park, H. Y.; Xu, Q.; Park, J. I.; Zvyagintseva, T.; Stonik, V. A.; Kwak, J. Y. Ligand of scavenger receptor class A indirectly induces maturation of human blood dendritic cells via production of tumor necrosis factor-alpha. Blood 2009, 113, 5839-5847.
    • (2009) Blood , vol.113 , pp. 5839-5847
    • Jin, J.O.1    Park, H.Y.2    Xu, Q.3    Park, J.I.4    Zvyagintseva, T.5    Stonik, V.A.6    Kwak, J.Y.7
  • 36
    • 77957331641 scopus 로고    scopus 로고
    • Fucoidan isolated from Laminaria angustata var. longissima induced macrophage activation
    • Teruya, T.; Takeda, S.; Tamaki, Y.; Tako, M. Fucoidan isolated from Laminaria angustata var. longissima induced macrophage activation. Biosci. Biotechnol. Biochem. 2010, 74, 1960-1962.
    • (2010) Biosci. Biotechnol. Biochem. , vol.74 , pp. 1960-1962
    • Teruya, T.1    Takeda, S.2    Tamaki, Y.3    Tako, M.4
  • 37
    • 72649092661 scopus 로고    scopus 로고
    • Structural characteristics and in vitro macrophage activation of acetyl fucoidan from Cladosiphon okamuranus
    • Teruya, T.; Tatemoto, H.; Konishi, T.; Tako, M. Structural characteristics and in vitro macrophage activation of acetyl fucoidan from Cladosiphon okamuranus. Glycoconj. J. 2009, 26, 1019-1028.
    • (2009) Glycoconj. J. , vol.26 , pp. 1019-1028
    • Teruya, T.1    Tatemoto, H.2    Konishi, T.3    Tako, M.4
  • 39
    • 36649003496 scopus 로고    scopus 로고
    • Defensive effects of a fucoidan from brown alga Undaria pinnatifida against herpes simplex virus infection
    • DOI 10.1016/j.intimp.2007.10.017, PII S1567576907003372
    • Hayashi, K.; Nakano, T.; Hashimoto, M.; Kanekiyo, K.; Hayashi, T. Defensive effects of a fucoidan from brown alga Undaria pinnatifida against herpes simplex virus infection. Int. Immunopharmacol. 2008, 8, 109-116. (Pubitemid 350199103)
    • (2008) International Immunopharmacology , vol.8 , Issue.1 , pp. 109-116
    • Hayashi, K.1    Nakano, T.2    Hashimoto, M.3    Kanekiyo, K.4    Hayashi, T.5
  • 40
    • 0041621601 scopus 로고    scopus 로고
    • Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida
    • Maruyama, H.; Tamauchi, H.; Hashimoto, M.; Nakano, T. Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida. In vivo (Athens, Greece) 2003, 17, 245-249. (Pubitemid 36958113)
    • (2003) Vivo , vol.17 , Issue.3 , pp. 245-249
    • Maruyama, H.1    Tamauchi, H.2    Hashimoto, M.3    Nakano, T.4
  • 41
    • 33846256216 scopus 로고    scopus 로고
    • The role of NK cells in antitumor activity of dietary fucoidan from Undaria pinnatifida sporophylls (Mekabu)
    • DOI 10.1055/s-2006-951703
    • Maruyama, H.; Tamauchi, H.; Iizuka, M.; Nakano, T. The role of NK cells in antitumor activity of dietary fucoidan from Undaria pinnatifida sporophylls (Mekabu). Planta Med. 2006, 72, 1415-1417. (Pubitemid 46102397)
    • (2006) Planta Medica , vol.72 , Issue.15 , pp. 1415-1417
    • Maruyama, H.1    Tamauchi, H.2    Iizuka, M.3    Nakano, T.4
  • 42
    • 31044444853 scopus 로고    scopus 로고
    • Immunomodulating activity of arabinogalactan and fucoidan in vitro
    • Choi, E. M.; Kim, A. J.; Kim, Y. O.; Hwang, J. K. Immunomodulating activity of arabinogalactan and fucoidan in vitro. J. Med. Food 2005, 8, 446-453.
    • (2005) J. Med. Food , vol.8 , pp. 446-453
    • Choi, E.M.1    Kim, A.J.2    Kim, Y.O.3    Hwang, J.K.4
  • 43
    • 23844554488 scopus 로고    scopus 로고
    • Suppression of Th2 immune responses by mekabu fucoidan from Undaria pinnatifida sporophylls
    • DOI 10.1159/000086422
    • Maruyama, H.; Tamauchi, H.; Hashimoto, M.; Nakano, T. Suppression of Th2 immune responses by mekabu fucoidan from Undaria pinnatifida sporophylls. Int. Arch. Allergy Immunol. 2005, 137, 289-294. (Pubitemid 41161019)
    • (2005) International Archives of Allergy and Immunology , vol.137 , Issue.4 , pp. 289-294
    • Maruyama, H.1    Tamauchi, H.2    Hashimoto, M.3    Nakano, T.4
  • 44
    • 70350446611 scopus 로고    scopus 로고
    • Different suppressive effects of fucoidan and lentinan on IL-8 mRNA expression in in vitro gut inflammation
    • Mizuno, M.; Nishitani, Y.; Hashimoto, T.; Kanazawa, K. Different suppressive effects of fucoidan and lentinan on IL-8 mRNA expression in in vitro gut inflammation. Biosci. Biotechnol. Biochem. 2009, 73, 2324-2325.
    • (2009) Biosci. Biotechnol. Biochem. , vol.73 , pp. 2324-2325
    • Mizuno, M.1    Nishitani, Y.2    Hashimoto, T.3    Kanazawa, K.4
  • 45
    • 33745699887 scopus 로고    scopus 로고
    • Fucoidan prevents concanavalin A-induced liver injury through induction of endogenous IL-10 in mice
    • Saito, A.; Yoneda, M.; Yokohama, S.; Okada, M.; Haneda, M.; Nakamura, K. Fucoidan prevents concanavalin A-induced liver injury through induction of endogenous IL-10 in mice. Hepatol. Res. 2006, 35, 190-198.
    • (2006) Hepatol. Res. , vol.35 , pp. 190-198
    • Saito, A.1    Yoneda, M.2    Yokohama, S.3    Okada, M.4    Haneda, M.5    Nakamura, K.6
  • 46
    • 67649403088 scopus 로고    scopus 로고
    • Fucoidan extracted from Fucus evanescens brown algae corrects immunity and hemostasis disorders in experimental endotoxemia
    • Kuznetsova, T. A. Fucoidan extracted from Fucus evanescens brown algae corrects immunity and hemostasis disorders in experimental endotoxemia. Bull. Exp. Biol. Med. 2009, 147, 66-69.
    • (2009) Bull. Exp. Biol. Med. , vol.147 , pp. 66-69
    • Kuznetsova, T.A.1
  • 47
    • 77952148025 scopus 로고    scopus 로고
    • The promise of glycomics, glycan arrays and carbohydrate-based vaccines
    • Lepenies, B.; Seeberger, P. H. The promise of glycomics, glycan arrays and carbohydrate-based vaccines. Immunopharmacol. Immunotoxicol. 2010, 32, 196-207.
    • (2010) Immunopharmacol. Immunotoxicol. , vol.32 , pp. 196-207
    • Lepenies, B.1    Seeberger, P.H.2
  • 48
    • 77952546022 scopus 로고    scopus 로고
    • Applications of synthetic carbohydrates to chemical biology
    • Lepenies, B.; Yin, J.; Seeberger, P. H. Applications of synthetic carbohydrates to chemical biology. Curr. Opin. Chem. Biol. 2010, 14, 404-411.
    • (2010) Curr. Opin. Chem. Biol. , vol.14 , pp. 404-411
    • Lepenies, B.1    Yin, J.2    Seeberger, P.H.3
  • 49
    • 57549098955 scopus 로고    scopus 로고
    • Chemical synthesis of all phosphatidylinositol mannoside (PIM) glycans from Mycobacterium tuberculosis
    • Boonyarattanakalin, S.; Liu, X.; Michieletti, M.; Lepenies, B.; Seeberger, P. H. Chemical synthesis of all phosphatidylinositol mannoside (PIM) glycans from Mycobacterium tuberculosis. J. Am. Chem. Soc. 2008, 130, 16791-16799.
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 16791-16799
    • Boonyarattanakalin, S.1    Liu, X.2    Michieletti, M.3    Lepenies, B.4    Seeberger, P.H.5
  • 50
    • 77957899290 scopus 로고    scopus 로고
    • Design, synthesis and biological evaluation of carbohydratefunctionalized cyclodextrins and liposomes for hepatocyte-specific targeting
    • Bernardes, G. J.; Kikkeri, R.; Maglinao, M.; Laurino, P.; Collot, M.; Hong, S. Y.; Lepenies, B.; Seeberger, P. H. Design, synthesis and biological evaluation of carbohydratefunctionalized cyclodextrins and liposomes for hepatocyte-specific targeting. Org. Biomol. Chem. 2010, 8, 4987-4996.
    • (2010) Org. Biomol. Chem. , vol.8 , pp. 4987-4996
    • Bernardes, G.J.1    Kikkeri, R.2    Maglinao, M.3    Laurino, P.4    Collot, M.5    Hong, S.Y.6    Lepenies, B.7    Seeberger, P.H.8
  • 51
    • 71849093174 scopus 로고    scopus 로고
    • Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonica
    • Wang, J.; Zhang, Q.; Zhang, Z.; Song, H.; Li, P. Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonica. Int. J. Biol. Macromol. 2010, 46, 6-12.
    • (2010) Int. J. Biol. Macromol. , vol.46 , pp. 6-12
    • Wang, J.1    Zhang, Q.2    Zhang, Z.3    Song, H.4    Li, P.5
  • 53
    • 34250796744 scopus 로고    scopus 로고
    • Anti-proliferative activity of oversulfated fucoidan from commercially cultured Cladosiphon okamuranus TOKIDA in U937 cells
    • DOI 10.1016/j.ijbiomac.2007.02.010, PII S0141813007000761
    • Teruya, T.; Konishi, T.; Uechi, S.; Tamaki, H.; Tako, M. Anti-proliferative activity of oversulfated fucoidan from commercially cultured Cladosiphon okamuranus TOKIDA in U937 cells. Int. J. Biol. Macromol. 2007, 41, 221-226. (Pubitemid 46990525)
    • (2007) International Journal of Biological Macromolecules , vol.41 , Issue.3 , pp. 221-226
    • Teruya, T.1    Konishi, T.2    Uechi, S.3    Tamaki, H.4    Tako, M.5
  • 55
    • 0030791796 scopus 로고    scopus 로고
    • Comparison of the anticoagulant action of sulfated and phosphorylated polysaccharides
    • DOI 10.1016/S0049-3848(97)00110-2, PII S0049384897001102
    • Dace, R.; McBride, E.; Brooks, K.; Gander, J.; Buszko, M.; Doctor, V. M. Comparison of the anticoagulant action of sulfated and phosphorylated polysaccharides. Thromb. Res. 1997, 87, 113-121. (Pubitemid 27333268)
    • (1997) Thrombosis Research , vol.87 , Issue.1 , pp. 113-121
    • Dace, R.1    McBride, E.2    Brooks, K.3    Gander, J.4    Buszko, M.5    Doctor, V.M.6
  • 56
    • 0037437728 scopus 로고    scopus 로고
    • Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities
    • DOI 10.1016/S0006-2952(02)01478-8, PII S0006295202014788
    • Koyanagi, S.; Tanigawa, N.; Nakagawa, H.; Soeda, S.; Shimeno, H. Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities. Biochem. Pharmacol. 2003, 65, 173-179. (Pubitemid 36015820)
    • (2003) Biochemical Pharmacology , vol.65 , Issue.2 , pp. 173-179
    • Koyanagi, S.1    Tanigawa, N.2    Nakagawa, H.3    Soeda, S.4    Shimeno, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.