Discovery of a novel enzymatic cleavage site for botulinum neurotoxin F5

FEBS Letters

Volumn 586, Issue 2, 2012, Pages 109-115

  Kalb, Suzanne R ^a   Baudys, Jakub ^a   Webb, Robert P ^b   Wright, Patrick ^b   Smith, Theresa J ^b   Smith, Leonard A ^c   Fernández, Rafael ^d   Raphael, Brian H ^e   Maslanka, Susan E ^e   Pirkle, James L ^a   Barr, John R ^a  

^a NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^b UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^c U S ARMY MEDICAL RESEARCH AND MATERIEL COMMAND   (United States)

^d UNIVERSIDAD NACIONAL DE CUYO   (Argentina)

^e NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

Author keywords

BoNT F; Botulinum neurotoxin; Mass spectrometry; Synaptobrevin 2

Indexed keywords

BOTULINUM TOXIN; BOTULINUM TOXIN F5; HYBRID PROTEIN; SYNAPTOBREVIN 2; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ENZYME SUBSTRATE COMPLEX; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; TOXIN ANALYSIS; TOXIN STRUCTURE; TOXIN SYNTHESIS;

AMINO ACID SEQUENCE; BOTULINUM TOXINS; CATALYTIC DOMAIN; CLONING, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE HYDROLASES; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPS; PROTEOLYSIS; SUBSTRATE SPECIFICITY; VESICLE-ASSOCIATED MEMBRANE PROTEIN 2;

EID: 84855757650     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.11.033     Document Type: Article

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