A metronidazole-resistant isolate of Blastocystis spp. Is susceptible to nitric oxide and downregulates intestinal epithelial inducible nitric oxide synthase by a novel parasite survival mechanism

Infection and Immunity

Volumn 79, Issue 12, 2011, Pages 5019-5026

  Mirza, Haris ^a   Wu, Zhaona ^a   Kidwai, Fahad ^b   Tan, Kevin S W ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; METRONIDAZOLE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; ANTIINFECTIVE AGENT; ARGINASE;

ANTIBIOTIC RESISTANCE; ARTICLE; BLASTOCYSTIS; DOWN REGULATION; HOST RESISTANCE; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; ISOLATION PROCEDURE; NITROSATIVE STRESS; NONHUMAN; PARASITOSIS; PRIORITY JOURNAL; STRAIN DIFFERENCE; SURVIVAL RATE; CELL STRAIN CACO 2; CLASSIFICATION; DRUG EFFECT; DRUG RESISTANCE; ENZYMOLOGY; GENE EXPRESSION REGULATION; INTESTINE CELL; METABOLISM; PARASITOLOGY;

ANTI-INFECTIVE AGENTS; ARGINASE; BLASTOCYSTIS; CACO-2 CELLS; DOWN-REGULATION; DRUG RESISTANCE; ENTEROCYTES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; METRONIDAZOLE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II;

EID: 84855736078     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.05632-11     Document Type: Article

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