Enantio- and diastereoselective synthesis of β,γ,γδ, -tetrasubstituted -methylene -δ-lactones

Synthesis

Volumn 2012, Issue 2, 2012, Pages 247-252

  Albrecht, Łukasz ^a   Deredas, Dariusz ^a   Wojciechowski, Jakub ^b   Wolf, Wojciech M ^b   Krawczyk, Henryk ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY   (Poland)

^b Technical University (Politechnika)   (Poland)

Author keywords

hydroxyaldehydes; methylene lactones; HWE olefination; Knoevenagel condensation; Michael addition

Indexed keywords

-METHYLENE - LACTONES; HYDROXYALDEHYDES; KNOEVENAGEL CONDENSATION; MICHAEL ADDITIONS; OLEFINATION;

ADDITION REACTIONS; CONDENSATION REACTIONS; STEREOSELECTIVITY;

SYNTHESIS (CHEMICAL);

1 (4 CYANOPROPYL) 2,2 DIMETHYL 3 OXOPROPYL(DIETHOXYPHOSPHORYL)ACETATE; 2,2 DIMETHYL 1 (4 NITROPHENYL) 3 OXOPROPYL(DIETHOXYPHOSPHORYL)ACETATE; 4 [3,3 DIMETHYL 5 METHYLENE 6 OXO 4 (2 OXOPROPYL)TETRAHYDRO 2H PYRAN 2 YL]BENZONITRILE; 5,5 DIMETHYL 3 METHYLENE 6 (4 NITROPHENYL) 4 (2 OXOPROPYL)TETRAHYDRO 2H PYRAN 2 ONE; ALPHA METHYLENE DELTA LACTONE DERIVATIVE; DIETHYL[5,5 DIMETHYL 6 (4 NITROPHENYL) 2 OXO 4 (2 OXOPROPYL)TETRAHYDRO 2H PYRAN 3 YL]PHOSPHONATE; DIETHYL[5,5 DIMETHYL 6 (4 NITROPHENYL) 2 OXO 5,6 DIHYDRO 2H PYRAN 3 YL]PHOSPHONATE; DIETHYL[6 (4 CYANOPHENYL) 5,5 DIMETHYL 2 OXO 4 (2 OXOPROPYL)TETRAHYDRO 2H PYRAN 3 YL]PHOSPHONATE; DIETHYL[6 (4 CYANOPHENYL) 5,5 DIMETHYL 2 OXO 5,6 DIHYDRO 2H PYRAN 3 YL]PHOSPHONATE; LACTONE DERIVATIVE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; DIASTEREOSELECTIVITY; ENANTIOSELECTIVITY; HORNER WADSWORTH EMMONS REACTION; MICHAEL ADDITION; STEREOCHEMISTRY; SYNTHESIS;

EID: 84855720768     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0031-1289629     Document Type: Article

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