Inhibition of α-glucosidase and hypoglycemic effect of stilbenes from the Amazonian plant Deguelia rufescens var urucu (Ducke) A.M.G. Azevedo (Leguminosae)

Planta Medica

Volumn 78, Issue 1, 2012, Pages 36-38

  Pereira, Aline C ^a   Arruda, Mara S P ^b   Da Silva, Ewerton A S ^b   Da Silva, Milton N ^b   Lemos, Virgínia S ^a   Cortes, Steyner F ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FEDERAL UNIVERSITY OF PARÁ   (Brazil)

Author keywords

glucosidase; Deguelia rufescens var. urucu; diabetes; Leguminosae; plasma glucose; stilbenes

Indexed keywords

3,5 DIMETHOXY 4' O PRENYL STILBENE; ACARBOSE; ALPHA GLUCOSIDASE; ANTIDIABETIC AGENT; LONCHOCARPENE; STILBENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEGUELIA RUFESCENS; DRUG ISOLATION; HYPERGLYCEMIA; HYPOGLYCEMIA; IC 50; IN VITRO STUDY; LEGUME; MOUSE; NONHUMAN;

ALPHA-GLUCOSIDASES; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS; FABACEAE; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; MALE; MICE; PHYTOTHERAPY; PLANT EXTRACTS; SOUTH AMERICA; STILBENES;

DEGUELIA; FABACEAE; MUS;

EID: 84855715772     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0031-1280199     Document Type: Article

References (24)

1. Stolar M W., Hoogwerf B J., Gorshow S M., Boyle P J., Wales D O. Managing type 2 diabetes: going beyond glycemic control. J Manag Care Pharm 2008 14 S2-S19
2. Lopez-Candales A. Metabolic syndrome X: a comprehensive review of the pathophysiology and recommended therapy. J Med 2001 32 283-300 (Pubitemid 34464466)
3. Ortiz-Andrade R R., García-Jiménez S, Castillo-Espaa P, Ramírez-vila G, Villalobos-Molina R, Estrada-Soto S. -Glucosidase inhibitory activity of the methanolic extract from Tournefortia hartwegiana: an anti-hyperglycemic agent. J Ethnopharmacol 2007 109 48-53 (Pubitemid 44889199)
4. Chiasson J L., Josse R G., Gomis R, Hanefeld M, Karasik A, Laakso M. Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomized trial. Lancet 2002 359 2072-2077 (Pubitemid 34680970)
5. Kawamori R, Tajima N, Iwamoto Y, Shimamoto K, Kaku K. Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance. Lancet 2009 373 1607-1614
6. Babu K S., Tiwari A K., Srinivas P V., All A Z., Raju B C., Rao J M. Yeast and mammalian -glucosidase inhibitory constituents from Himalayan rhubarb Rheum emodi Wall. ex Meisson. Bioorg Med Chem Lett 2004 14 3841-3845 (Pubitemid 38760090)
7. Kerem Z, Bilkis I, Flaishman M A., Sivan L. Antioxidant activity and inhibition of -glucosidase by trans-resveratrol, Piceid, and a novel trans-stilbene from the roots of Israeli Rumex bucephalophorus L. J Agric Food Chem 2006 54 1243-1247 (Pubitemid 43374216)
8. Lam S H., Chen J M., Kang C J., Chen C H., Lee S S. Alpha-glucosidase inhibitors from the seeds of Syagrus romanzoffiana. Phytochemistry 2008 69 1173-1178
9. Choi S Z., Lee S O., Jang K U., Chung S H., Park S H., Kang H C., Yang E Y., Cho H J., Lee K R. Antidiabetic stilbene and anthraquinone derivatives from Rheum undulatum. Arch Pharm Res 2005 28 1027-1030 (Pubitemid 41426847)
10. Hung L M., Chen J K., Huang S S., Lee R S., Su M J. Cardioprotective effect of resveratrol, a natural antioxidant derived from grapes. Cardiovasc Res 2000 47 549-555
11. Das S, Alagappan V K., Bagchi D, Sharma H S., Maulik N, Das D K. Coordinated induction of iNOS-VEGF-KDR-eNOS after resveratrol consumption: a potential mechanism for resveratrol preconditioning of the heart. Vasc Pharmacol 2005 42 281-289 (Pubitemid 40726331)
12. Lôbo L T., Silva G A., Freitas M C. C., Filho A P. S. S., Silva M N., Arruda A C., Guilhon G M. S. P., Santos L S., Santos A S., Arruda M S. P. Stilbenes from Deguelia rufescens var. urucu (Ducke) A. M. G. Azevedo leaves: effects on seed germination and plant growth. J Braz Chem Soc 2010 21 1838-1844
13. Gusmão S D., Páscoa V, Mathias L, Curcino Vieira I J., Braz-Filho R, Alves Lemos F J. Derris (Lonchocarpus) urucu (Leguminosae) extract modifies the peritrophic matrix structure of Aedes aegypt (Diptera: Culicidae). Mems Inst Oswaldo Cruz 2002 97 371-375 (Pubitemid 135746493)
14. Mors W B., Do Nascimento M C., Ribeiro do Valle J, Aragão J A. Ichthyotoxic activity of plants of the genus Derris and compounds isolated there from. Ci Cult 1973 25 647-648
15. Fang N, Casida J E. Cubé resin insecticide: identification and biological activity of 29 rotenoid constituents. J Agric Food Chem 1999 47 2130-2136 (Pubitemid 29438773)
16. Fang N, Casida J E. New bioactive flavonoids and stilbenes in cubé resin insecticide. J Nat Prod 1999 62 205-210 (Pubitemid 29137889)
17. Lôbo L T., Silva G A., Ferreira M, da Silva M N., Santos A S., Arruda A C., Guilhon G M. P., Santos L S., Borges R S., Arruda M S. P. Dihydroflavonols from the leaves of Derris urucu (Leguminosae): structural elucidation and DPPH radical-scavenging activity. J Braz Chem Soc 2009 20 1082-1088
18. Ma C M., Hattori M, Daneshtalab M, Wang L. Chlorogenic acid derivatives with alkyl chains of different lengths and orientations: potent -glucosidase inhibitors. J Med Chem 2008 51 6188-6194
19. Hanozet G, Pircher H P., Vanni P, Oesch B, Semenza G. An example of enzyme hysteresis. The slow and tight interaction of some fully competitive inhibitors with small intestinal sucrose. J Biol Chem 1981 256 3703-3711
20. Li T, Zhang X D., Song Y W., Liu J W. A microplate-based screening method for -glucosidase inhibitors. Nat Prod Res Dev 2005 10 1128-1134
21. Li H, Song F, Xing J, Tsao R, Liu Z, Liu S. Screening and structural characterization of -glucosidase inhibitors from hawthorn leaf flavonoids extract by ultrafiltration LC-DAD-MS n and SORI-CID FTICR MS. J Am Soc Mass Spectrom 2009 20 1496-1503
22. Aguilar-Santamaría L, Ramírez G, Nicasio P, Alegría-Reyes C, Herrera-Arellano A. Antidiabetic activities of Tecoma stans (L.) Juss. ex Kunth. J Ethnopharmacol 2009 124 284-288
23. Heo S J., Hwang J Y., Choi J I., Han J S., Kim H J., Jeon Y J. Diphlorethohydroxycarmalol isolated from Ishige okamurae, a brown algae, a potent -glucosidase and -amylase inhibitor, alleviates postprandial hyperglycemia in diabetic mice. Eur J Pharmacol 2009 615 252-256
24. Martins M R., Vieira A K. G., Souza E P. G., Moura A S. Early overnutrition impairs insulin signaling in the heart of adult Swiss mice. J Endocrinol 2008 198 591-598