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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 2, 2012, Pages 1255-1262

Lead Diversification 2: Application to P38, gMTP and lead compounds

(11) Masood, M Abid a Bazin, Marc a,b Bunnage, Mark E a Calabrese, Andrew a,c Cox, Mark a Fancy, Sally Ann a Farrant, Elizabeth a Pearce, David W a Perez, Manuel a Hitzel, Laure a Peakman, Torren a

a PFIZER GLOBAL RESEARCH AND DEVELOPMENT (United Kingdom)

b Hepatochem (United States)

c CELGENE CORPORATION (United States)

Author keywords

Biomimetic; Fluorination; Lead Diversification; Metalloporphyrin; P38

Indexed keywords

AMINOQUINOLINE DERIVATIVE; CYTOCHROME P450; METALLOPORPHYRIN; PYRAZOLE DERIVATIVE; PYRIMIDINONE DERIVATIVE;

ARTICLE; CHEMICAL PROCEDURES; CHEMICAL STRUCTURE; CHLORINATION; CONFORMATIONAL TRANSITION; FLUORINATION; IC 50; LEAD DIVERSIFICATION; NONHUMAN; OXIDATION; PURIFICATION; STRUCTURE ACTIVITY RELATION;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; HUMANS; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PALLADIUM; PROTEIN KINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84855702075 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.11.033 Document Type: Article

Times cited : (14)

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