8R-Lipoxygenase-catalyzed synthesis of a prominent cis-epoxyalcohol from dihomo-γ-linolenic acid: A distinctive transformation compared with S-lipoxygenases

Journal of Lipid Research

Volumn 53, Issue 2, 2012, Pages 292-299

  Jin, Jing ^a   Boeglin, William E ^a   Cha, Jin K ^b   Brash, Alan R ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

18O 2 incorporation; Arachidonic acid; Gas liquid chromatography mass spectrometry; Hepoxilin; Plexaura homomalla; Sharpless epoxidation; Total synthesis; Trans epoxide

Indexed keywords

ALCOHOL DERIVATIVE; ALLENE OXIDE SYNTHASE; DIHOMO GAMMA LINOLENIC ACID; EPOXYALCOHOL; LIPOXYGENASE; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CORAL; ENZYME ACTIVITY; ENZYME PURIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID METABOLISM; MASS FRAGMENTOGRAPHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PLEXAURA HOMOMALLA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNTHESIS; ULTRAVIOLET RADIATION;

8,11,14-EICOSATRIENOIC ACID; ANIMALS; ANTHOZOA; ARACHIDONATE LIPOXYGENASES; EPOXY COMPOUNDS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; INTRAMOLECULAR OXIDOREDUCTASES; LIPOXYGENASE; MAGNETIC RESONANCE SPECTROSCOPY; SUBSTRATE SPECIFICITY;

EID: 84855671060     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M022863     Document Type: Article

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