The rat leukocyte-type 12-lipoxygenase exhibits an intrinsic hepoxilin A3 synthase activity

Journal of Biological Chemistry

Volumn 279, Issue 28, 2004, Pages 29023-29030

  Nigam, Santosh ^a   Patabhiraman, Shankarnarayanan ^a   Ciccoli, Roberto ^a   Ishdorj, Ganchimeg ^a   Schwarz, Kristin ^b   Petrucev, Branka ^a   Kühn, Hartmut ^b   Haeggström, Jesper Z ^c  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CELLS; ISOMERS; MUTAGENESIS;

ARACHIDONIC ACID; HEPOXILINS;

ENZYMES;

12 HYDROPEROXY 5,8,10,14 ICOSATETRAENOIC ACID; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONIC ACID; HEPOXILIN A; HEPOXILIN A SYNTHETASE; ICOSANOID; ISOENZYME; PORCINE LEUKOCYTE TYPE ARACHIDONATE 12 LIPOXYGENASE; RABBIT RETICULOCYTE TYPE ARACHIDONATE 12 LIPOXYGENASE; RAT LEUKOCYTE TYPE ARACHIDONATE 12 LIPOXYGENASE; RECOMBINANT ENZYME; RECOMBINANT HUMAN PLATELET TYPE ARACHIDONATE 12 LIPOXYGENASE; SYNTHETASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CANCER CELL CULTURE; CATALYSIS; CELL STRAIN RINM5F; CYTOSOL; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME SPECIFICITY; IMMUNOPRECIPITATION; INSULINOMA; ISOMER; MOLECULAR CLONING; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; ARACHIDONATE 5-LIPOXYGENASE; ARACHIDONIC ACIDS; CELL LINE, TUMOR; HUMANS; INSULINOMA; INTRAMOLECULAR OXIDOREDUCTASES; ISOENZYMES; LEUKOCYTES; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; RABBITS; RATS; SEQUENCE ALIGNMENT;

ANIMALIA; ORYCTOLAGUS CUNICULUS; PERO; PICHIA; PICHIA PASTORIS; SUIDAE;

EID: 3142763362     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M307576200     Document Type: Article

References (30)

1. Pace-Asciak, C. R., Granstrom, E., and Samuelsson, B. (1983) J. Biol. Chem. 258, 6835-6840
2. Pace-Asciak, C. R., and Martin, J. M. (1984) Prostaglandins Leukotrienes Med. 16, 173-180
3. Dho, S., Grinstein, S., Corey, E. J., Su, W. G., and Pace-Asciak, C. R. (1990) Biochem. J. 266, 63-68
4. Laneuville, O., Reynaud, D., Grinstein, S., Nigam, S., and Pace-Asciak, C. R. (1993) Biochem. J. 295, 393-397
5. Nigam, S., Nodes, S., Cichon, G., Corey, E. J., and Pace-Asciak, C. R. (1990) Biochem. Biophys. Res. Commun. 171, 944-948
6. Piomelli, D., Shapiro, E., Zipkin, R., Schwartz, J. H., and Feinmark, S. J. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 1721-1725
7. Piomelli, D., Volterra, A., Dale, N., Siegelbaum, S. A., Kandel, E. R., Schwartz, J. H., and Belardetti, F. (1987) Nature 328, 38-43
8. Margalit, A., Sofer, Y., Grossman, S., Reynaud, D., Pace-Asciak, C. R., and Livne, A. A. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 2589-2592
9. Belardetti, F., Campbell, W. B., Falck, J. R., Demontis, G., and Rosolowsky, M. (1989) Neuron 3, 497-505
10. Reynaud, D., Delton, I., Gharib, A., Sada, N., Lagarde, M., and Pace-Asciak, C. R. (1994) J. Neurochem. 62, 126-133
11. Shankaranarayanan, P., Ciccoli, R., and Nigam, S. (2003) FEBS Lett. 538, 107-112
12. Pace-Asciak, C. R., Reynaud, D., and Demin, P. (1995) J. Lipid Mediat. Cell Signal. 12, 307-311
13. Pace-Asciak, C. R., Reynaud, D., and Demin, P. (1995) Lipids 30, 107-114
14. Garssen, G. J., Veldink, G. A., Vliegenthart, J. F., and Boldingh, J. (1976) Eur. J. Biochem. 62, 33-36
15. Bryant, R. W., and Bailey, J. M. (1979) Prostaglandins 17, 9-18
16. Shimizu, T., Radmark, O., and Samuelsson, B. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 689-693
17. Schwarz, K., Gerth, C., Anton, M., and Kühn, H. (2000) Biochemistry 39, 14515-14521
18. Kühn, H., Wiesner, R., Alder, Schewe, T., and Stender, H. (1986) FEBS Lett. 208, 248-252
19. Serhan, C. N., Takano, T., Gronert, C., Chiang, N., and Clish, C. B. (1999) Clin. Chem. Lab. Med. 37, 299-309
20. Romano, M., Chen, X. S., Takahashi, Y., Yamamoto, S., and Funk, C. D. (1993) Biochem. J. 296, 127-133
21. Demin, P., Reynaud, D., and Pace-Asciak, C. R. (1995) Anal. Biochem. 226, 252-255
22. Richards, K. M., Moody, J. S., and Marnett, L. J. (1999) Biochemistry 38, 16529-16538
23. Moody, J. S., and Marnett, L. J. (2002) Biochemistry 41, 10297-10303
24. Sloane, D. L., Leung, R., Craik, C. S., and Siegel, E. (1991) Nature 354, 149-152
25. Borngräber, S., Kuban, R. J., Anton, M., and Kühn, H. (1996) J. Mol. Biol. 264, 1145-1153
26. Borngräber, S., Browner, M., Gillmor, S., Gerth, C., Anton, M., Fletterick, R., and Kuhn, H. (1999) J. Biol. Chem. 274, 37245-37350
27. Walther, M., Ivanov, I., Myagkova, G., and Kuhn, H. (2001) Chem. Biol. 8, 779-790
28. Watanabe, T., and Haeggström, J. Z. (1993) Biochem. Biophys. Res. Commun. 192, 1023-1029
29. Ivanov, I., Rathmann, J., Myagkova, G., and Kuhn, H. (2001) Biochemistry 40, 10223-10229
30. Schewe, T., Rapoport, S. M., and Kuhn, H. (1986) Adv. Enzymol. Relat. Areas Mol. Biol. 53, 191-272