-
1
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
DOI 10.1126/science.1141634
-
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007; 316: 889-894. (Pubitemid 46764279)
-
(2007)
Science
, vol.316
, Issue.5826
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
Perry, J.R.B.7
Elliott, K.S.8
Lango, H.9
Rayner, N.W.10
Shields, B.11
Harries, L.W.12
Barrett, J.C.13
Ellard, S.14
Groves, C.J.15
Knight, B.16
Patch, A.-M.17
Ness, A.R.18
Ebrahim, S.19
Lawlor, D.A.20
Ring, S.M.21
Ben-Shlomo, Y.22
Jarvelin, M.-R.23
Sovio, U.24
Bennett, A.J.25
Melzer, D.26
Ferrucci, L.27
Loos, R.J.F.28
Barroso, I.29
Wareham, N.J.30
Karpe, F.31
Owen, K.R.32
Cardon, L.R.33
Walker, M.34
Hitman, G.A.35
Palmer, C.N.A.36
Doney, A.S.F.37
Morris, A.D.38
Smith, G.D.39
Hattersley, A.T.40
McCarthy, M.I.41
more..
-
2
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
DOI 10.1038/ng2048, PII NG2048
-
Dina C, Meyre D, Gallina S, Durand E, Körner A, Jacobson P et al. Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 2007; 39: 724-726. (Pubitemid 46848595)
-
(2007)
Nature Genetics
, vol.39
, Issue.6
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Korner, A.5
Jacobson, P.6
Carlsson, L.M.S.7
Kiess, W.8
Vatin, V.9
Lecoeur, C.10
Delplanque, J.11
Vaillant, E.12
Pattou, F.13
Ruiz, J.14
Weill, J.15
Levy-Marchal, C.16
Horber, F.17
Potoczna, N.18
Hercberg, S.19
Le Stunff, C.20
Bougneres, P.21
Kovacs, P.22
Marre, M.23
Balkau, B.24
Cauchi, S.25
Chevre, J.-C.26
Froguel, P.27
more..
-
3
-
-
57749121512
-
An obesity-associated FTO gene variant and increased energy intake in children
-
Cecil JE, Tavendale R,Watt P, Hetherington MM, Palmer CNA. An obesity-associated FTO gene variant and increased energy intake in children. N Engl J Med 2008; 359: 2558-2566.
-
(2008)
N Engl J Med
, vol.359
, pp. 2558-2566
-
-
Cecil, J.E.1
Tavendale, R.2
Watt, P.3
Hetherington, M.M.4
Palmer, C.N.A.5
-
4
-
-
53849088890
-
The fat mass-and obesity-associated locus and dietary intake in children
-
Timpson NJ, Emmett PM, Frayling TM, Rogers I, Hattersley AT, McCarthy MI et al. The fat mass-and obesity-associated locus and dietary intake in children. Am J Clin Nutr 2008; 88: 971-978.
-
(2008)
Am J Clin Nutr
, vol.88
, pp. 971-978
-
-
Timpson, N.J.1
Emmett, P.M.2
Frayling, T.M.3
Rogers, I.4
Hattersley, A.T.5
McCarthy, M.I.6
-
5
-
-
72449169954
-
The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI
-
Zhao J, Bradfield JP, LiM,Wang K, Zhang H, Kim CE et al. The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI. Obesity (Silver Spring) 2009; 17: 2254-2257.
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 2254-2257
-
-
Zhao, J.1
Bradfield, J.P.2
Li, M.3
Wang, K.4
Zhang, H.5
Kim, C.E.6
-
6
-
-
50649089800
-
Replication of the genetic effects of FTO polymorphisms on BMI in a Korean population
-
Cha SW, Choi SM, Kim KS, Park BL, Kim JR, Kim JY et al. Replication of the genetic effects of FTO polymorphisms on BMI in a Korean population. Obesity (Silver Spring) 2008; 16: 2187-2189.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 2187-2189
-
-
Cha, S.W.1
Choi, S.M.2
Kim, K.S.3
Park, B.L.4
Kim, J.R.5
Kim, J.Y.6
-
7
-
-
50949104331
-
Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population
-
Chang Y-C, Liu P-H, Lee W-J, Chang T-J, Jiang Y-D, Li H-Y et al. Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population. Diabetes 2008; 57: 2245-2252.
-
(2008)
Diabetes
, vol.57
, pp. 2245-2252
-
-
Chang, Y.-C.1
Liu, P.-H.2
Lee, W.-J.3
Chang, T.-J.4
Jiang, Y.-D.5
Li, H.-Y.6
-
8
-
-
44349129013
-
Variations in the FTO gene are associated with severe obesity in the Japanese
-
DOI 10.1007/s10038-008-0283-1
-
Hotta K, Nakata Y, Matsuo T, Kamohara S, Kotani K, Komatsu R et al. Variations in the FTO gene are associated with severe obesity in the Japanese. J Hum Genet 2008; 53: 546-553. (Pubitemid 351749344)
-
(2008)
Journal of Human Genetics
, vol.53
, Issue.6
, pp. 546-553
-
-
Hotta, K.1
Nakata, Y.2
Matsuo, T.3
Kamohara, S.4
Kotani, K.5
Komatsu, R.6
Itoh, N.7
Mineo, I.8
Wada, J.9
Masuzaki, H.10
Yoneda, M.11
Nakajima, A.12
Miyazaki, S.13
Tokunaga, K.14
Kawamoto, M.15
Funahashi, T.16
Hamaguchi, K.17
Yamada, K.18
Hanafusa, T.19
Oikawa, S.20
Yoshimatsu, H.21
Nakao, K.22
Sakata, T.23
Matsuzawa, Y.24
Tanaka, K.25
Kamatani, N.26
Nakamura, Y.27
more..
-
9
-
-
48249100977
-
Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) cohort
-
Marvelle AF, Lange LA, Qin L, Adair LS, Mohlke KL. Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) cohort. Diabetes 2008; 57: 1987-1991.
-
(2008)
Diabetes
, vol.57
, pp. 1987-1991
-
-
Marvelle, A.F.1
Lange, L.A.2
Qin, L.3
Adair, L.S.4
Mohlke, K.L.5
-
10
-
-
50449104632
-
Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6719 Asians
-
Ng MCY, Park KS, Oh B, Tam CHT, Cho YM, Shin HD et al. Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6719 Asians. Diabetes 2008; 57: 2226-2233.
-
(2008)
Diabetes
, vol.57
, pp. 2226-2233
-
-
Ng, M.C.Y.1
Park, K.S.2
Oh, B.3
Tam, C.H.T.4
Cho, Y.M.5
Shin, H.D.6
-
11
-
-
55849104388
-
FTO variants are associated with obesity in the Chinese and Malay populations in Singapore
-
Tan JT, Dorajoo R, Seielstad M, Sim XL, Ong RT, Chia KS et al. FTO variants are associated with obesity in the Chinese and Malay populations in Singapore. Diabetes 2008; 57: 2851-2857.
-
(2008)
Diabetes
, vol.57
, pp. 2851-2857
-
-
Tan, J.T.1
Dorajoo, R.2
Seielstad, M.3
Sim, X.L.4
Ong, R.T.5
Chia, K.S.6
-
12
-
-
36448953082
-
FTO polymorphisms in oceanic populations
-
DOI 10.1007/s10038-007-0198-2
-
Ohashi J, Naka I, Kimura R, Natsuhara K, Yamauchi T, Furusawa T et al. FTO polymorphisms in oceanic populations. J Hum Genet 2007; 52: 1031-1035. (Pubitemid 350164612)
-
(2007)
Journal of Human Genetics
, vol.52
, Issue.12
, pp. 1031-1035
-
-
Ohashi, J.1
Naka, I.2
Kimura, R.3
Natsuhara, K.4
Yamauchi, T.5
Furusawa, T.6
Nakazawa, M.7
Ataka, Y.8
Patarapotikul, J.9
Nuchnoi, P.10
Tokunaga, K.11
Ishida, T.12
Inaoka, T.13
Matsumura, Y.14
Ohtsuka, R.15
-
13
-
-
49249104932
-
Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan
-
Horikawa Y, Miyake K, Yasuda K, Enya M, Hirota Y, Yamagata K et al. Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan. J Clin Endocrinol Metab 2008; 93: 3136-3141.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 3136-3141
-
-
Horikawa, Y.1
Miyake, K.2
Yasuda, K.3
Enya, M.4
Hirota, Y.5
Yamagata, K.6
-
14
-
-
38449097877
-
Variants in the Fat Mass-and Obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population
-
Li H,Wu Y, Loos RJF, Hu FB, Liu Y,Wang J et al. Variants in the Fat Mass-and Obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population. Diabetes 2008; 57: 264-268.
-
(2008)
Diabetes
, vol.57
, pp. 264-268
-
-
Li, H.1
Wu, Y.2
Loos, R.J.F.3
Hu, F.B.4
Liu, Y.5
Wang, J.6
-
15
-
-
46249094941
-
Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP
-
Grant SFA, Li M, Bradfield JP, Kim CE, Annaiah K, Santa E et al. Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP. PLoS ONE 2008; 3: e1746.
-
(2008)
PLoS ONE
, vol.3
-
-
Grant, S.F.A.1
Li, M.2
Bradfield, J.P.3
Kim, C.E.4
Annaiah, K.5
Santa, E.6
-
16
-
-
64049095449
-
FTO gene variation and measures of body mass in an African population
-
Hennig BJ, Fulford AJ, Sirugo G, Rayco-Solon P, Hattersley AT, Frayling TM et al. FTO gene variation and measures of body mass in an African population. BMC Med Genet 2009; 10: 21.
-
(2009)
BMC Med Genet
, vol.10
, pp. 21
-
-
Hennig, B.J.1
Fulford, A.J.2
Sirugo, G.3
Rayco-Solon, P.4
Hattersley, A.T.5
Frayling, T.M.6
-
17
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
-
Scuteri A, Sanna S, Chen W-M, Uda M, Albai G, Strait J et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 2007; 3: e115.
-
(2007)
PLoS Genet
, vol.3
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.-M.3
Uda, M.4
Albai, G.5
Strait, J.6
-
18
-
-
77953191271
-
FTO genetic variation and association with obesity in West Africans and African Americans
-
Adeyemo A, Chen G, Zhou J, Shriner D, Doumatey A, Huang H et al. FTO genetic variation and association with obesity in West Africans and African Americans. Diabetes 2010; 59: 1549-1554.
-
(2010)
Diabetes
, vol.59
, pp. 1549-1554
-
-
Adeyemo, A.1
Chen, G.2
Zhou, J.3
Shriner, D.4
Doumatey, A.5
Huang, H.6
-
19
-
-
65249108267
-
FTO genotype is associated with body mass index after the age of seven years but not with energy intake or leisure-time physical activity
-
Hakanen M, Raitakari OT, Lehtimäki T, Peltonen N, Pahkala K, Sillanmäki L et al. FTO genotype is associated with body mass index after the age of seven years but not with energy intake or leisure-time physical activity. J Clin Endocrinol Metab 2009; 94: 1281-1287.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 1281-1287
-
-
Hakanen, M.1
Raitakari, O.T.2
Lehtimäki, T.3
Peltonen, N.4
Pahkala, K.5
Sillanmäki, L.6
-
20
-
-
42049117134
-
The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks
-
DOI 10.1210/jc.2007-2343
-
López-Bermejo A, Petry CJ, Diaz M, Sebastiani G, de Zegher F, Dunger DB et al. The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks. J Clin Endocrinol Metab 2008; 93: 1501-1505. (Pubitemid 351519755)
-
(2008)
Journal of Clinical Endocrinology and Metabolism
, vol.93
, Issue.4
, pp. 1501-1505
-
-
Lopez-Bermejo, A.1
Petry, C.J.2
Diaz, M.3
Sebastiani, G.4
De Zegher, F.5
Dunger, D.B.6
Ibanez, L.7
-
22
-
-
58149303021
-
Increasing heritability of BMI and stronger associations with the FTO gene over childhood
-
Haworth CMA, Carnell S, Meaburn EL, Davis OSP, Plomin R, Wardle J. Increasing heritability of BMI and stronger associations with the FTO gene over childhood. Obesity (Silver Spring) 2008; 16: 2663-2668.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 2663-2668
-
-
Haworth, C.M.A.1
Carnell, S.2
Meaburn, E.L.3
Osp, D.4
Plomin, R.5
Wardle, J.6
-
23
-
-
39949083566
-
Major gender differences in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes
-
Jacobsson JA, Danielsson P, Svensson V, Klovins J, Gyllenstein U, Marcus C et al. Major gender differences in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes. Biochem Biophys Res Comm 2008; 368: 476-482.
-
(2008)
Biochem Biophys Res Comm
, vol.368
, pp. 476-482
-
-
Jacobsson, J.A.1
Danielsson, P.2
Svensson, V.3
Klovins, J.4
Gyllenstein, U.5
Marcus, C.6
-
24
-
-
0004146974
-
Cardiovascular risk factors in children
-
Oxford University Press: New York
-
Berenson GS, McMahan CA, Voors AW,Webber LS, Srinivasan SR, Frank GC et al. Cardiovascular Risk Factors in Children. The Early Natural History of Atherosclerosis and Essential Hypertension. Oxford University Press: New York, 1980.
-
(1980)
The Early Natural History of Atherosclerosis and Essential Hypertension
-
-
Berenson, G.S.1
McMahan, C.A.2
Voors, A.W.3
Webber, L.S.4
Srinivasan, S.R.5
Frank, G.C.6
-
25
-
-
0030972735
-
Development of cardiovascular risk factors from ages 8 to 18 in Project Heartbeat!: Study design and patterns of change in plasma total cholesterol concentration
-
Labarthe DR, Nichaman MZ, Harrist RB, Grunbaum JA, Dai S, for the Project HeartBeat! Investigators. Development of cardiovascular risk factors from ages 8 to 18 in Project HeartBeat! Study design and patterns of change in plasma total cholesterol concentration. Circulation 1997; 95: 2636-2642. (Pubitemid 27255492)
-
(1997)
Circulation
, vol.95
, Issue.12
, pp. 2636-2642
-
-
Labarthe, D.R.1
Nichaman, M.Z.2
Harrist, R.B.3
Grunbaum, J.A.4
Dai, S.5
-
26
-
-
0034864916
-
447-Stop polymorphism of lipoprotein lipase is associated with variation in longitudinal serum high-density lipoprotein-cholesterol profiles: The Bogalusa Heart Study
-
DOI 10.1053/meta.2001.24918
-
Hallman DM, Srinivasan SR, Elkasabany A, Boerwinkle E, Berenson GS. The Ser447-Stop polymorphism of lipoprotein lipase is associated with variation in longitudinal serum high-density lipoprotein-cholesterol profiles: The Bogalusa Heart Study. Metabolism 2001; 50: 894-904. (Pubitemid 32755005)
-
(2001)
Metabolism: Clinical and Experimental
, vol.50
, Issue.8
, pp. 894-904
-
-
Hallman, D.M.1
Srinivasan, S.R.2
Elkasabany, A.3
Boerwinkle, E.4
Berenson, G.S.5
-
27
-
-
4344659423
-
3-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: The Bogalusa Heart Study
-
DOI 10.1016/j.metabol.2004.03.019, PII S002604950400191X
-
Hallman DM, Srinivasan SR, ChenW, Boerwinkle E, Berenson GS. The beta(2)-adrenergic receptor Arg16-Gly polymorphism and interactions involving beta(2)-and beta(3)-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: The Bogalusa Heart Study. Metabolism 2004; 53: 1184-1191. (Pubitemid 39140755)
-
(2004)
Metabolism: Clinical and Experimental
, vol.53
, Issue.9
, pp. 1184-1191
-
-
Hallman, D.M.1
Srinivasan, S.R.2
Chen, W.3
Boerwinkle, E.4
Berenson, G.S.5
-
28
-
-
0020263707
-
Longitudinal trends and continuity in weight/stature from 3 months to 18 years
-
Cronk CE, Roche AF, Kent R, Berkey C, Reed RB, Valadian I et al. Longitudinal trends and continuity in weight/stature2 from 3 months to 18 years. Hum Biol 1982; 54: 729-749. (Pubitemid 13117034)
-
(1982)
Human Biology
, vol.54
, Issue.4
, pp. 729-749
-
-
Cronk, C.E.1
Roche, A.F.2
Kent, R.3
-
29
-
-
0035187571
-
Body mass index growth in a sample of U.S. children: Repeated measures data analysis of the Minneapolis children's blood pressure study
-
DOI 10.1002/ajhb.1127
-
Hlaing WM, Prineas RJ, Zhu Y, Leaverton PE. Body mass index growth in a sample of US children: repeated measures data analysis of the Minneapolis Children's Blood Pressure Study. Am J Human Biol 2001; 13: 821-831. (Pubitemid 33085733)
-
(2001)
American Journal of Human Biology
, vol.13
, Issue.6
, pp. 821-831
-
-
Hlaing, W.M.1
Prineas, R.J.2
Zhu, Y.3
Leaverton, P.E.4
-
30
-
-
0033653736
-
Body mass index during childhood, adolescence and young adulthood in relation to adult overweight and adiposity: The Fels Longitudinal Study
-
Guo SS, Huang C, Maynard LM, Demerath E, Towne B, Chumlea WC et al. Body mass index during childhood, adolescence and young adulthood in relation to adult overweight and adiposity: the Fels Longitudinal Study. Int J Obes 2000; 24: 1628-1635.
-
(2000)
Int J Obes
, vol.24
, pp. 1628-1635
-
-
Guo, S.S.1
Huang, C.2
Maynard, L.M.3
Demerath, E.4
Towne, B.5
Chumlea, W.C.6
-
31
-
-
51849166353
-
Impact on weight dynamics and general growth of the common FTO rs9939609: A Longitudinal Danish Cohort Study
-
Jess T, Zimermann E, Kring SII, Berentzen T, Holst C, Toubro S et al. Impact on weight dynamics and general growth of the common FTO rs9939609: a Longitudinal Danish Cohort Study. Int J Obes 2008; 32: 1388-1394.
-
(2008)
Int J Obes
, vol.32
, pp. 1388-1394
-
-
Jess, T.1
Zimermann, E.2
Sii, K.3
Berentzen, T.4
Holst, C.5
Toubro, S.6
-
32
-
-
77949894041
-
Life course variations in the associations between FTO and MC4R gene variants and body size
-
Hardy R, Wills AK, Wong A, Elks CE, Wareham NJ, Loos RJF et al. Life course variations in the associations between FTO and MC4R gene variants and body size. Hum Mol Genet 2010; 19: 545-552.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 545-552
-
-
Hardy, R.1
Wills, A.K.2
Wong, A.3
Elks, C.E.4
Wareham, N.J.5
Loos, R.J.F.6
-
33
-
-
58149340093
-
Fat mass-and obesity-associated (FTO) gene variant is associated with obesity.Longitudinal analyses in two cohort studies and functional test
-
Qi L, Kang K, Zhang C, van Dam RM, Kraft P, Hunter D et al. Fat mass-and obesity-associated (FTO) gene variant is associated with obesity. Longitudinal analyses in two cohort studies and functional test. Diabetes 2008; 57: 3145-3151.
-
(2008)
Diabetes
, vol.57
, pp. 3145-3151
-
-
Qi, L.1
Kang, K.2
Zhang, C.3
Van Dam, R.M.4
Kraft, P.5
Hunter, D.6
|