Methyl- and acetyltransferases are stable epigenetic markers postmortem

Cell and Tissue Banking

Volumn 12, Issue 4, 2011, Pages 289-297

  Monoranu, Camelia Maria ^a,b   Grünblatt, Edna ^a,h,i   Bartl, Jasmin ^a   Meyer, Andrea ^a   Apfelbacher, Manuela ^b   Keller, Daniela ^a   Michel, Tanja M ^a,g   Al Saraj, Safa ^e   Schmitt, Andrea ^d,f   Falkai, Peter ^f   Roggendorf, Wolfgang ^a,b   Deckert, Jürgen ^a   Ferrer, Isidro ^c   Riederer, Peter ^a  

^a Clinic and Policlinic for Psychiatry   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF GÖTTINGEN   (Germany)

^g RWTH AACHEN UNIVERSITY   (Germany)

^h UNIVERSITY OF ZURICH   (Switzerland)

ⁱ Psychosomatic and Psychotherapy   (Germany)

Author keywords

Tubulin; Acetyltransferase; GFAP; Methyltransferase; Postmortem; RNA; TAU; Tryptophan

Indexed keywords

ACYLTRANSFERASE; BIOLOGICAL MARKER; METHYLTRANSFERASE; RNA; TRYPTOPHAN;

ADULT; AGED; ARTICLE; CADAVER; FEMALE; GENETIC EPIGENESIS; HUMAN; MALE; METABOLISM; MIDDLE AGED; NONPARAMETRIC TEST; TISSUE PRESERVATION;

ACETYLTRANSFERASES; ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; EPIGENESIS, GENETIC; FEMALE; HUMANS; MALE; METHYLTRANSFERASES; MIDDLE AGED; POSTMORTEM CHANGES; RNA; STATISTICS, NONPARAMETRIC; TISSUE PRESERVATION; TRYPTOPHAN;

EID: 84855653734     PISSN: 13899333     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10561-010-9199-z     Document Type: Article

References (39)

1. Barrachina M, Ferrer I (2009) DNA methylation of Alzheimer disease and tauopathy-related genes in postmortem brain. J Neuropathol Exp Neurol 68:880-891
2. Barrachina M, Maes T, Buesa C, Ferrer I (2006) Lysosomeassociated membrane protein 1 (LAMP-1) in Alzheimer's disease. Neuropathol Appl Neurobiol 32:505-516 (Pubitemid 44401512)
3. Barton AJ, Pearson RC, Najlerahim A, Harrison PJ (1993) Preand postmortem influences on brain RNA. J Neurochem 61: 1-11 (Pubitemid 23175878)
4. Beach TG, Sue LI, Walker DG, Roher AE, Lue L, Vedders L, Connor DJ, Sabbagh MN, Rogers J (2008) The Sun Health Research Institute Brain Donation Program: Description and experience, 1987-2007. Cell Tissue Bank 9:229-245
5. Bell JE, Alafuzoff I, Al-Sarraj S, Arzberger T, Bogdanovic N, Budka H, Dexter DT, Falkai P, Ferrer I, Gelpi E, Gentleman SM, Giaccone G, Huitinga I, Ironside JW, Klioueva N, Kovacs GG, Meyronet D, Palkovits M, Parchi P, Patsouris E, Reynolds R, Riederer P, Roggendorf W, Seilhean D, Schmitt A, Schmitz P, Streichenberger N, Schwalber A, Kretzschmar H (2008) Management of a twenty-first century brain bank: Experience in the BrainNet Europe consortium. Acta Neuropathol 115:497-507
6. Birkmayer W, Riederer P (1980) Die Parkinson-Krankheit: Biochemie, Klinik, Therapie. Springer-Verlag
7. Buesa C, Maes T, Subirada F, Barrachina M, Ferrer I (2004) DNA chip technology in brain banks: Confronting a degrading world. J Neuropathol Exp Neurol 63:1003-1014 (Pubitemid 39372585)
8. Chandana R, Mythri RB, Mahadevan A, Shankar SK, Srinivas Bharath MM (2009) Biochemical analysis of protein stability in human brain collected at different post-mortem intervals. Indian J Med Res 129:189-199
9. Chevyreva I, Faull RL, Green CR, Nicholson LF (2008) Assessing RNA quality in postmortem human brain tissue. Exp Mol Pathol 84:71-77 (Pubitemid 351163260)
10. Crecelius A, Gotz A, Arzberger T, Frohlich T, Arnold GJ, Ferrer I, Kretzschmar HA (2008) Assessing quantitative postmortem changes in the gray matter of the human frontal cortex proteome by 2-D DIGE. Proteomics 8:1276-1291 (Pubitemid 351462933)
11. Ernst C, Deleva V, Deng X, Sequeira A, Pomarenski A, Klempan T, Ernst N, Quirion R, Gratton A, Szyf M, TureckiG(2009) Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completers. Arch Gen Psychiatry 66:22-32
12. Ervin JF, Heinzen EL, Cronin KD, Goldstein D, Szymanski MH, Burke JR, Welsh-Bohmer KA, Hulette CM (2007) Postmortem delay has minimal effect on brain RNA integrity. J Neuropathol Exp Neurol 66:1093-1099 (Pubitemid 350294659)
13. Ferrer I, Armstrong J, Capellari S, Parchi P, Arzberger T, Bell J, Budka H, Strobel T, Giaccone G, Rossi G, Bogdanovic N, Fakai P, Schmitt A, Riederers P, Al-Sarraj S, Ravid R, Kretzschmar H (2007a) Effects of formalin fixation, paraffin embedding, and time of storage on DNA preservation in brain tissue: A BrainNet Europe study. Brain Pathol 17:297-303 (Pubitemid 47000638)
14. Ferrer I, Santpere G, Arzberger T, Bell J, Blanco R, Boluda S, Budka H, Carmona M, Giaccone G, Krebs B, Limido L, Parchi P, Puig B, Strammiello R, Strobel T, Kretzschmar H (2007b) Brain protein preservation largely depends on the postmortem storage temperature: Implications for study of proteins in human neurologic diseases and management of brain banks: A BrainNet Europe Study. J Neuropathol Exp Neurol 66:35-46 (Pubitemid 46066787)
15. Ferrer I, Martinez A, Boluda S, Parchi P, Barrachina M (2008) Brain banks: Benefits, limitations and cautions concerning the use of post-mortem brain tissue for molecular studies. Cell Tissue Bank 9:181-194
16. Grinberg LT, Ferretti RE, Farfel JM, Leite R, Pasqualucci CA, Rosemberg S, Nitrini R, Saldiva PH, Filho WJ (2007) Brain bank of the Brazilian aging brain study group - a milestone reached and more than 1, 600 collected brains. Cell Tissue Bank 8:151-162 (Pubitemid 46681599)
17. Grünblatt E, Monoranu CM, Apfelbacher M, Keller D, Michel TM, Alafuzoff I, Ferrer I, Al-Saraj S, Keyvani K, Schmitt A, Falkai P, Schittenhelm J, McLean C, Halliday GM, Harper C, Deckert J, Roggendorf W, Riederer P (2009) Tryptophan is a marker of human postmortem brain tissue quality. J Neurochem 110:1400-1408
18. Hynd MR, Lewohl JM, Scott HL, Dodd PR (2003) Biochemical and molecular studies using human autopsy brain tissue. J Neurochem 85:543-562 (Pubitemid 36531920)
19. Keller S, SarchiaponeM, Zarrilli F,Videtic A, Ferraro A, Carli V, Sacchetti S, Lembo F, Angiolillo A, Jovanovic N, Pisanti F, Tomaiuolo R, Monticelli A, Balazic J, Roy A, Marusic A, Cocozza S, Fusco A, Bruni CB, Castaldo G, Chiariotti L (2010) Increased BDNF promoter methylation in theWernicke area of suicide subjects. Arch Gen Psychiatry 67:258-267
20. Kretzschmar H (2009) Brain banking: opportunities, challenges and meaning for the future. Nat Rev Neurosci 10:70-78
21. Kundakovic M, Chen Y, Guidotti A, Grayson DR (2009) The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes. Mol Pharmacol 75:342-354
22. Li E, Bird A (2007) DNA methylation in mammals. In: Allis C, Jenuwein T, Reinberg D (eds) Epigenetics. Cold Spring Harbor Laboratory Press, New York NY, pp 341-356
23. McGowan PO, Sasaki A, D'Alessio AC, Dymov S, Labonte B, Szyf M, Turecki G, Meaney MJ (2009) Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 12:342-348
24. Mohajerani MH, Sivakumaran S, Zacchi P, Aguilera P, Cherubini E (2007) Correlated network activity enhances synaptic efficacy via BDNF and the ERK pathway at immature CA3 CA1 connections in the hippocampus. Proc Natl Acad Sci USA 104:13176-13181 (Pubitemid 351737612)
25. Monoranu CM, Apfelbacher M, Grünblatt E, Puppe B, Alafuzoff I, Ferrer I, Al-Saraj S, Keyvani K, Schmitt A, Falkai P, Schittenhelm J, Halliday G, Kril J, Harper C, McLean C, Riederer P, Roggendorf W (2009) pH measurement as quality control on human post mortem brain tissue: A study of the BrainNet Europe consortium. Neuropathol Appl Neurobiol 35:329-337
26. Omalu BI, Mancuso JA, Cho P, Wecht CH (2005) Diagnosis of Alzheimer's disease in an exhumed decomposed brain after twenty months of burial in a deep grave. J Forensic Sci 50:1453-1458 (Pubitemid 41642475)
27. Perrett CW, Marchbanks RM, Whatley SA (1988) Characterisation of messenger RNA extracted post-mortem from the brains of schizophrenic, depressed and control subjects. J Neurol Neurosurg Psychiatry 51:325-331 (Pubitemid 18097563)
28. Pope TW, Raymond L, Foresman L, Pinson D, Joag SV, Marcario J, Berman NE, Raghavan R, Cheney PD, Narayan O, Wilkinson S, Gordon MA (1997) Texture analysis of cerebral white matter in SIV-infected macaque monkeys. J Neurosci Methods 74:53-64 (Pubitemid 27250250)
29. Popova T, Mennerich D, Weith A, QuastK(2008) Effect ofRNA quality on transcript intensity levels in microarray analysis of human post-mortem brain tissues. BMC Genomics 9:91
30. Santpere G, Puig B, Ferrer I (2006) Low molecular weight species of tau in Alzheimer's disease are dependent on tau phosphorylation sites but not on delayed post-mortem delay in tissue processing. Neurosci Lett 399:106-110
31. Schmitt A, Bauer M, Heinsen H, Feiden W, Brainnet E, II, Falkai P, Alafuzoff I, Arzberger T, Al-Sarraj S, Bell JE, Bogdanovic N, Bruck W, Budka H, Ferrer I, Giaccone G, Kovacs GG, Meyronet D, Palkovits M, Parchi P, Patsouris E, Ravid R, Reynolds R, Riederer P, Roggendorf W, Schwalber A, Seilhean D, Kretzschmar H (2007) How a neuropsychiatric brain bank should be run: A consensus paper of Brainnet Europe II. J Neural Transm 114:527-537 (Pubitemid 46664046)
32. Stan AD, Ghose S, Gao XM, Roberts RC, Lewis-Amezcua K, Hatanpaa KJ, Tamminga CA (2006) Human postmortem tissue: What quality markers matter? Brain Res 1123:1-11
33. Tamura Y, Kunugi H, Ohashi J, Hohjoh H (2007) Epigenetic aberration of the human REELIN gene in psychiatric disorders. Mol Psychiatry 12(519):93-600
34. Tomita H, Vawter MP, Walsh DM, Evans SJ, Choudary PV, Li J, Overman KM, Atz ME, Myers RM, Jones EG, Watson SJ, Akil H, Bunney WE Jr (2004) Effect of agonal and postmortem factors on gene expression profile: Quality control in microarray analyses of postmortem human brain. Biol Psychiatry 55:346-352 (Pubitemid 38199983)
35. Waldvogel HJ, Bullock JY, Synek BJ, Curtis MA, van Roon- Mom WM, Faull RL (2008) The collection and processing of human brain tissue for research. Cell Tissue Bank 9: 169-179
36. Xue H, Xian B, Dong D, Xia K, Zhu S, Zhang Z, Hou L, Zhang Q, Zhang Y, Han JD (2007) A modular network model of aging. Mol Syst Biol 3:147
37. Zhubi A, Veldic M, Puri NV, Kadriu B, Caruncho H, Loza I, Sershen H, Lajtha A, Smith RC, Guidotti A, Davis JM, Costa E (2009) An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes. Schizophr Res 111:115-122
38. Vienna Bradford MM (1976) Rapid and sensitive method for quantitation of microgram quantities of proteins utilizing principle of protein dye binding. Anal Biochem 72:248-254
39. NIH Sheet 17 (2001), Procurement and use of human biological materials for research (http://ohsr.od.nih.gov/info/sheet17. html)