Aged red garlic extract reduces cigarette smoke extract-induced cell death in human bronchial smooth muscle cells by increasing intracellular glutathione levels

Phytotherapy Research

Volumn 26, Issue 1, 2012, Pages 18-25

  Jeong, Yi Yeong ^a   Park, Hye Jin ^a   Cho, Young Woo ^a   Kim, Eun Jin ^a   Kim, Gyu Tae ^a   Mun, Yun Ja ^a   Lee, Jong Deog ^a   Shin, Jung Hye ^a   Sung, Nak Ju ^a   Kang, Dawon ^a   Han, Jaehee ^a  

^a Gyeongsang National University   (South Korea)

Author keywords

bronchiole; garlic; glutathione; reactive oxygen species; smoking; smooth muscle

Indexed keywords

AGED BLACK GARLIC EXTRACT; AGED RED GARLIC EXTRACT; BUTHIONINE SULFOXIMINE; CASPASE; CIGARETTE SMOKE; FRESH RAW GARLIC EXTRACT; GARLIC EXTRACT; GLUTATHIONE; HEME OXYGENASE 1; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ISOLATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; HUMAN BRONCHIAL SMOOTH MUSCLE CELL; HUMAN CELL; INHIBITION KINETICS; PROTEIN EXPRESSION; REGULATORY MECHANISM; SMOOTH MUSCLE FIBER;

ALLIUM; ANTIOXIDANTS; BRONCHI; CASPASES; CELL DEATH; CELL LINE; GLUTATHIONE; HEME OXYGENASE-1; HUMANS; LUNG DISEASES; MUSCLE CELLS; MUSCLE, SMOOTH; PHYTOTHERAPY; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; SMOKE; SMOKING;

ALLIUM NIGRUM; ALLIUM SATIVUM;

EID: 84855648022     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3502     Document Type: Article

References (30)

1. Baglole CJ, Sime PJ, Phipps RP,. 2008. Cigarette smoke-induced expression of heme oxygenase-1 in human lung fibroblasts is regulated by intracellular glutathione. Am J Physiol Lung Cell Mol Physiol 295: L624-L636.
2. Ban JO, Cho JS, Hwang IG, et al,. 2009. Anti-cancer effect of the combination of thiacremonone and docetaxel by inactivation of NF-kB in human cancer cells. Biomol Ther 17: 403-411.
3. Banerjee S, Chattopadhyay R, Ghosh A, et al,. 2008. Cellular and molecular mechanisms of cigarette smoke-induced lung damage and prevention by vitamin C. J Inflamm Lond 5: 21.
4. Butt MS, Sultan MT,. 2009. Levels of trans fats in diets consumed in developing economies. J AOAC Int 92: 1277-1283.
5. Butt MS, Sultan MT, Butt MS, Iqbal J,. 2009. Garlic: nature's protection against physiological threats. Crit Rev Food Sci Nutr 49: 538-551.
6. Chen C, Pung D, Leong V, et al,. 2004a. Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals. Free Radic Biol Med 37: 1578-1590. (Pubitemid 39349804)
7. Chen GG, Liu ZM, Vlantis AC, Tse GM, Leung BC, van Hasselt CA,. 2004b. Heme oxygenase-1 protects against apoptosis induced by tumor necrosis factor-alpha and cycloheximide in papillary thyroid carcinoma cells. J Cell Biochem 92: 1246-1256. (Pubitemid 44264233)
8. Cheng SE, Lee IT, Lin CC, Kou YR, Yang CM,. 2010. Cigarette smoke particle-phase extract induces HO-1 expression in human tracheal smooth muscle cells: role of the c-Src/NADPH oxidase/MAPK/Nrf2 signaling pathway. Free Radic Biol Med 48: 1410-1422.
9. Circu ML, Stringer S, Rhoads CA, Moyer MP, Aw TY,. 2009. The role of GSH efflux in staurosporine-induced apoptosis in colonic epithelial cells. Biochem Pharmacol 77: 76-85.
10. Ewing JF, Maines MD,. 1993. Glutathione depletion induces heme oxygenase-1 (HSP32) mRNA and protein in rat brain. J Neurochem 60: 1512-1519. (Pubitemid 23088329)
11. Fratelli M, Goodwin LO, Orom UA, et al,. 2005. Gene expression profiling reveals a signaling role of glutathione in redox regulation. Proc Natl Acad Sci USA 102: 13998-14003. (Pubitemid 41377692)
12. Gong P, Hu B, Cederbaum AI,. 2004. Diallyl sulfide induces heme oxygenase-1 through MAPK pathway. Arch Biochem Biophys 432: 252-260. (Pubitemid 39470021)
13. Graf BA, Milbury PE, Blumberg JB,. 2005. Flavonols, flavones, flavanones, and human health: epidemiological evidence. J Med Food 8: 281-290. (Pubitemid 41502409)
14. Hug H, Enari M, Nagata S,. 1994. No requirement of reactive oxygen intermediates in Fas-mediated apoptosis. FEBS Lett 351: 311-313. (Pubitemid 24285323)
15. Imai J, Ide N, Nagae S, Moriguchi T, Matsuura H, Itakura Y,. 1994. Antioxidant and radical scavenging effects of aged garlic extract and its constituents. Planta Med 60: 417-420. (Pubitemid 24330767)
16. Johnson PR, Burgess JK, Underwood PA, et al,. 2004. Extracellular matrix proteins modulate asthmatic airway smooth muscle cell proliferation via an autocrine mechanism. J Allergy Clin Immunol 113: 690-696. (Pubitemid 38530425)
17. Kamp DW, Greenberger MJ, Sbalchierro JS, Preusen SE, Weitzman SA,. 1998. Cigarette smoke augments asbestos-induced alveolar epithelial cell injury: role of free radicals. Free Radic Biol Med 25: 728-739. (Pubitemid 28464940)
18. Langer C, Jurgensmeier JM, Bauer G,. 1996. Reactive oxygen species act at both TGF-beta-dependent and -independent steps during induction of apoptosis of transformed cells by normal cells. Exp Cell Res 222: 117-124. (Pubitemid 26043717)
19. Lee SJ, Shin JH, Kang MJ, et al,. 2010. Antioxidants activity of aged red garlic. J Life Sci 20: 775-781.
20. Lee YM, Gweon OC, Seo YJ, et al,. 2009. Antioxidant effect of garlic and aged black garlic in animal model of type 2 diabetes mellitus. Nutr Res Pract 3: 156-161.
21. Liu JD, Tsai SH, Lin SY, et al,. 2004a. Thiol antioxidant and thiol-reducing agents attenuate 15-deoxy-delta 12,14-prostaglandin J2-induced heme oxygenase-1 expression. Life Sci 74: 2451-2463.
22. Liu ZM, Chen GG, Ng EK, Leung WK, Sung JJ, Chung SC,. 2004b. Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells. Oncogene 23: 503-513. (Pubitemid 38175005)
23. Nana-Sinkam SP, Lee JD, Sotto-Santiago S, et al,. 2007. Prostacyclin prevents pulmonary endothelial cell apoptosis induced by cigarette smoke. Am J Respir Crit Care Med 175: 676-685. (Pubitemid 46536482)
24. Pryor WA, Stone K,. 1993. Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite. Ann NY Acad Sci 686: 12-27; discussion 27-18.
25. Rahman I, MacNee W,. 1999. Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease. Am J Physiol 277: L1067-L1088. (Pubitemid 30046033)
26. Shishodia S, Potdar P, Gairola CG, Aggarwal BB,. 2003. Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1. Carcinogenesis 24: 1269-1279. (Pubitemid 36927068)
27. van der Vaart H, Postma DS, Timens W, ten Hacken NH,. 2004. Acute effects of cigarette smoke on inflammation and oxidative stress: a review. Thorax 59: 713-721. (Pubitemid 39061538)
28. Velmurugan K, Alam J, McCord JM, Pugazhenthi S,. 2009. Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim. Free Radic Biol Med 46: 430-440.
29. Wilson EA, Demmig-Adams B,. 2007. Antioxidant, anti-inflammatory, and antimicrobial properties of garlic and onions. Nutr Food Sci 37: 178-183. (Pubitemid 47108333)
30. Yoshimura S, Banno Y, Nakashima S, et al,. 1999. Inhibition of neutral sphingomyelinase activation and ceramide formation by glutathione in hypoxic PC12 cell death. J Neurochem 73: 675-683. (Pubitemid 29339841)