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Volumn 20, Issue 3, 2011, Pages 215-225

Protective effect of curcumin and its combination with piperine (bioavailability enhancer) against haloperidol-associated neurotoxicity: Cellular and neurochemical evidence

Author keywords

Apoptosis; Caspase 3; Curcumin; Haloperidol; NF kappaB; Tardive dyskinesia

Indexed keywords

CASPASE 3; CLOZAPINE; CURCUMIN; DOPAMINE; HALOPERIDOL; NITRIC OXIDE; NORADRENALIN; PIPERINE; SEROTONIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84855644032     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-010-9229-4     Document Type: Article
Times cited : (43)

References (77)
  • 1
    • 0033764665 scopus 로고    scopus 로고
    • Tumor necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappaB
    • Aggarwal BB (2000) Tumor necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappaB. Ann Rheum D 59(Suppl 1):6-16
    • (2000) Ann Rheum D , vol.59 , Issue.SUPPL. 1 , pp. 6-16
    • Aggarwal, B.B.1
  • 2
    • 15044361086 scopus 로고    scopus 로고
    • Suppression of the nuclear factor-κB activation pathway by spice-derived phytochemicals: Reasoning for seasoning
    • DOI 10.1196/annals.1329.054
    • Aggarwal BB, Shishodia S (2004) Suppression of the nuclear factorkappaB activation pathway by spice-derived phytochemicals: Reasoning for seasoning. Ann N Y Acad Sci 1030:434-441 (Pubitemid 40378943)
    • (2004) Annals of the New York Academy of Sciences , vol.1030 , pp. 434-441
    • Aggarwal, B.B.1    Shishodia, S.2
  • 3
    • 1642300863 scopus 로고    scopus 로고
    • The role of TNF and its family members in inflammation and cancer: Lessons from gene deletion
    • Aggarwal BB, Shishodia S, Ashikawa K, Bharti AC (2002) The role of TNF and its family members in inflammation and cancer: Lessons from gene deletion. Curr Drug Targets Inflamm Allergy 1(4):327-341
    • (2002) Curr Drug Targets Inflamm Allergy , vol.1 , Issue.4 , pp. 327-341
    • Aggarwal, B.B.1    Shishodia, S.2    Ashikawa, K.3    Bharti, A.C.4
  • 6
    • 0021931513 scopus 로고
    • Biochemical basis of enhanced drug bioavailability by piperine: Evidence that piperine is a potent inhibitor of drug metabolism
    • Atal CK, Dubey RK, Singh JJ (1985) Biochemical basis of enhanced drug bioavailability by piperine: Evidence that piperine is a potent inhibitor of drug metabolism. Pharmacol Exp Ther 232:258-262 (Pubitemid 15193683)
    • (1985) Journal of Pharmacology and Experimental Therapeutics , vol.232 , Issue.1 , pp. 258-262
    • Atal, C.K.1    Dubey, R.K.2    Singh, J.3
  • 7
    • 0015596284 scopus 로고
    • Biological defense mechanism. The production by leukocytes of superoxide, a potential bacterial agent
    • Babior BM, Kipner RS, Cerutte JT (1973) Biological defense mechanism. The production by leukocytes of superoxide, a potential bacterial agent. J Clin Investig 52:741-744
    • (1973) J Clin Investig , vol.52 , pp. 741-744
    • Babior, B.M.1    Kipner, R.S.2    Cerutte, J.T.3
  • 9
    • 34249283362 scopus 로고    scopus 로고
    • Possible anti-oxidant and neuroprotective mechanisms of zolpidem in attenuating typical anti-psychotic-induced orofacial dyskinesia-A biochemical and neurochemical study
    • DOI 10.1016/j.pnpbp.2007.04.007, PII S0278584607001388
    • Bishnoi M, Chopra K, Kulkarni SK (2007a) Possible anti-oxidant and neuroprotective mechanisms of zolpidem in attenuating typical anti-psychotic-induced orofacial dyskinesia-A biochemical and neurochemical study. Prog Neuropsychopharmacol Biol Psychiatry 31(5):1130-1138 (Pubitemid 46810111)
    • (2007) Progress in Neuro-Psychopharmacology and Biological Psychiatry , vol.31 , Issue.5 , pp. 1130-1138
    • Bishnoi, M.1    Chopra, K.2    Kulkarni, S.K.3
  • 10
    • 34047249399 scopus 로고    scopus 로고
    • Comparative neurochemical changes associated with chronic administration of typical and atypical neuroleptics: Implications in tardive dyskinesia
    • Bishnoi M, Kumar A, Chopra K, Kulkarni SK (2007b) Comparative neurochemical changes associated with chronic administration of typical and atypical neuroleptics: Implications in tardive dyskinesia. Indian J Exp Biol 45(2):175-179
    • (2007) Indian J Exp Biol , vol.45 , Issue.2 , pp. 175-179
    • Bishnoi, M.1    Kumar, A.2    Chopra, K.3    Kulkarni, S.K.4
  • 11
    • 37249010259 scopus 로고    scopus 로고
    • Protective effect of Curcumin, the active principle of turmeric (Curcuma longa) in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes in rat brain
    • Bishnoi M, Chopra K, Kulkarni SK (2008a) Protective effect of Curcumin, the active principle of turmeric (Curcuma longa) in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes in rat brain. Pharmacol Biochem Behav 88:511-520
    • (2008) Pharmacol Biochem Behav , vol.88 , pp. 511-520
    • Bishnoi, M.1    Chopra, K.2    Kulkarni, S.K.3
  • 12
    • 48049101604 scopus 로고    scopus 로고
    • Activation of striatal inflammatory mediators and caspase-3 is central to haloperidolinduced orofacial dyskinesia
    • Bishnoi M, Chopra K, Kulkarni SK (2008b) Activation of striatal inflammatory mediators and caspase-3 is central to haloperidolinduced orofacial dyskinesia. Eur J Pharmacol 590(1-3): 241-245
    • (2008) Eur J Pharmacol , vol.590 , Issue.1-3 , pp. 241-245
    • Bishnoi, M.1    Chopra, K.2    Kulkarni, S.K.3
  • 13
    • 84984532203 scopus 로고    scopus 로고
    • Acute reserpine and subchronic haloperidol treatments change synaptosomal brain glutamate uptake and elicit orofacial dyskinesia in rats
    • DOI 10.1016/j.brainres.2004.10.038, PII S0006899304017688
    • Burger MBE, Fachineto R, Alves A, Callegari L, Rocha JBT (2005) Acute reserpine and sub-chronic haloperidol treatments change synaptosomal brain glutamate uptake and elicit orofacial dyskinesia in rats. Brain Res 1031(2):202-210 (Pubitemid 40103531)
    • (2005) Brain Research , vol.1031 , Issue.2 , pp. 202-210
    • Burger, M.E.1    Fachineto, R.2    Alves, A.3    Callegari, L.4    Rocha, J.B.T.5
  • 15
    • 0034918051 scopus 로고    scopus 로고
    • Serotonin depletion produces long lasting increase in striatal glutamatergic transmission
    • DOI 10.1046/j.1471-4159.2001.00242.x
    • Cara DB, Dusticier N, Forni C, Lievens JC, Daszuta A (2001) Serotonin depletion produces long lasting increase in striatal glutamatergic transmission. J Neurochem 78:240-248 (Pubitemid 32664405)
    • (2001) Journal of Neurochemistry , vol.78 , Issue.2 , pp. 240-248
    • Di Cara, B.1    Dusticier, N.2    Forni, C.3    Lievens, J.C.4    Daszuta, A.5
  • 16
    • 33947532054 scopus 로고    scopus 로고
    • Curcumin attenuates the expression of IL-1beta, IL-6, and TNF-alpha as well as cyclin E in TNF-alpha-treated HaCaT cells; NF-kappaB and MAPKs as potential upstream targets
    • Cho JW, Lee KS, Kim CW (2007) Curcumin attenuates the expression of IL-1beta, IL-6, and TNF-alpha as well as cyclin E in TNF-alpha-treated HaCaT cells; NF-kappaB and MAPKs as potential upstream targets. Int J Mol Med 19(3):469-474
    • (2007) Int J Mol Med , vol.19 , Issue.3 , pp. 469-474
    • Cho, J.W.1    Lee, K.S.2    Kim, C.W.3
  • 17
    • 21244501367 scopus 로고    scopus 로고
    • Column chromatography analysis of brain tissue: An advanced laboratory exercise for neuroscience majors
    • Church WH (2005) Column chromatography analysis of brain tissue: An advanced laboratory exercise for neuroscience majors. J Undergrad Neurosci Educ 3(2):A36-A41 (Pubitemid 40902202)
    • (2005) Journal of Undergraduate Neuroscience Education , vol.3 , Issue.2
    • Church, W.H.1
  • 18
    • 18044365379 scopus 로고    scopus 로고
    • 1A receptor activation
    • DOI 10.1016/j.brainres.2005.02.072
    • Cosi C, Waget A, Rollet K, Tesori V, Newman-Tancredi A (2005) Clozapine, ziprasidone and aripiprazole but not haloperidol protect against kainic acid-induced lesion of the striatum in mice, in vivo: Role of 5-HT1A receptor activation. Brain Res 1043(1-2):32-41 (Pubitemid 40603369)
    • (2005) Brain Research , vol.1043 , Issue.1-2 , pp. 32-41
    • Cosi, C.1    Waget, A.2    Rollet, K.3    Tesori, V.4    Newman-Tancredi, A.5
  • 19
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle JT, Puttfarcken P (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science 262(5134):689-695 (Pubitemid 23350687)
    • (1993) Science , vol.262 , Issue.5134 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 20
    • 0017255979 scopus 로고
    • Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
    • Creese I, Burt D, Snyder SH (1976) Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science 192:481-483
    • (1976) Science , vol.192 , pp. 481-483
    • Creese, I.1    Burt, D.2    Snyder, S.H.3
  • 21
    • 0030474172 scopus 로고    scopus 로고
    • Serotonin depletion exacerbates changes in striatal gene expression following quinolinic acid injection
    • DOI 10.1016/S0006-8993(96)01053-0, PII S0006899396010530
    • Cummings TJ, Walker PD (1996) Serotonin depletion exacerbates changes in striatal gene expression following quinolinic acid injection. Brain Res 743(1-2):240-248 (Pubitemid 27028777)
    • (1996) Brain Research , vol.743 , Issue.1-2 , pp. 240-248
    • Cummings, T.J.1    Walker, P.D.2
  • 22
    • 25444490459 scopus 로고    scopus 로고
    • 3 receptors and their association with tardive dyskinesia in severe mental illness
    • DOI 10.1097/01.jcp.0000177546.34799.af
    • De Leon J, Susce MT, Pan RM, Koch WH, Wedlund PJ (2005) Polymorphic variations in GSTM1, GSTT1, PgP, CYP2D6, CYP3A5, and dopamine D2 and D3 receptors and their association with tardive dyskinesia in severe mental illness. J Clin Psychopharmacol 25(5):448-456 (Pubitemid 41368367)
    • (2005) Journal of Clinical Psychopharmacology , vol.25 , Issue.5 , pp. 448-456
    • De Leon, J.1    Susce, M.T.2    Pan, R.-M.3    Koch, W.H.4    Wedlund, P.J.5
  • 23
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82:70-77
    • (1959) Arch Biochem Biophys , vol.82 , pp. 70-77
    • Ellman, G.L.1
  • 25
    • 0034742718 scopus 로고    scopus 로고
    • 2 impairs inflammatory mediator release from immunologically stimulated RBL-2H3 cells through a redox-sensitive, calcium-dependent mechanism
    • Guerin-Marchand C, Sénéchal H, Pelletier C, Fohrer H, Olivier R, David B, Berthon B (2001) H2O2 impairs inflammatory mediator release from immunologically stimulated RBL-2H3 cells through a redox-sensitive, calcium-dependent mechanism. Inflamm Res 150:341-349 (Pubitemid 32675395)
    • (2001) Inflammation Research , vol.50 , Issue.7 , pp. 341-349
    • Guerin-Marchand, C.1    Senechal, H.2    Pelletier, C.3    Fohrer, H.4    Olivier, R.5    David, B.6    Berthon, B.7    Blank, U.8
  • 28
    • 1442264399 scopus 로고    scopus 로고
    • Apoptotic Proteins in the Temporal Cortex in Schizophrenia: High Bax/Bcl-2 Ratio without Caspase-3 Activation
    • DOI 10.1176/appi.ajp.161.1.109
    • Jarskog LF, Selinger ES, Lieberman JA, Gilmore JH (2004) Apoptotic proteins in the temporal cortex in schizophrenia: High Bax/Bcl-2 ratio without caspase-3 activation. Am J Psychiatry 161:109-115 (Pubitemid 38419315)
    • (2004) American Journal of Psychiatry , vol.161 , Issue.1 , pp. 109-115
    • Jarskog, L.F.1    Selinger, E.S.2    Lieberman, J.A.3    Gilmore, J.H.4
  • 29
    • 33845684744 scopus 로고    scopus 로고
    • Caspase-3 activation in rat frontal cortex following treatment with typical and atypical antipsychotics
    • DOI 10.1038/sj.npp.1301074, PII 1301074
    • Jarskog LF, Gilmore JH, Glantz LA, Gable KL, German TT, Tong RI, Lieberman JA (2007) Caspase-3 activation in rat frontal cortex following treatment with typical and atypical antipsychotics. Neuropsychopharmacology 32:95-102 (Pubitemid 44967787)
    • (2007) Neuropsychopharmacology , vol.32 , Issue.1 , pp. 95-102
    • Jarskog, L.F.1    Gilmore, J.H.2    Glantz, L.A.3    Gable, K.L.4    German, T.T.5    Tong, R.I.6    Lieberman, J.A.7
  • 30
    • 0035868406 scopus 로고    scopus 로고
    • Thyrotropin modifies activation of nuclear factor κB by tumour necrosis factor α in rat thyroid cell line
    • DOI 10.1042/0264-6021:3540573
    • Kikumori T, Kambe F, Nagaya T, Funahashi H, Seo H (2001) Thyrotrophin modifies activation of nuclear factor kappaB by tumor necrosis factor-alpha in rat thyroid cell line. Biochem J 354:573-579 (Pubitemid 32269720)
    • (2001) Biochemical Journal , vol.354 , Issue.3 , pp. 573-579
    • Kikumori, T.1    Kambe, F.2    Nagaya, T.3    Funahashi, H.4    Seo, H.5
  • 31
    • 3543088026 scopus 로고    scopus 로고
    • Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice
    • Lambert JD, Hong J, Kim DH, Mishin VM, Yang CS (2004) Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin- 3-gallate in mice. J Nutr 134(8):1948-1952 (Pubitemid 39031322)
    • (2004) Journal of Nutrition , vol.134 , Issue.8 , pp. 1948-1952
    • Lambert, J.D.1    Hong, J.2    Kim, D.H.3    Mishin, V.M.4    Yang, C.S.5
  • 34
    • 33644607597 scopus 로고    scopus 로고
    • Haplotype analysis of endothelial nitric oxide synthase (NOS3) genetic variants and tardive dyskinesia in patients with schizophrenia
    • Liou YJ, Lai IC, Lin MW, Bai YM, Lin CC, Liao DL, Chen JY, Lin CY, Wang YC (2006) Haplotype analysis of endothelial nitric oxide synthase (NOS3) genetic variants and tardive dyskinesia in patients with schizophrenia. Pharmacogenet Genomics 16(3): 151-157
    • (2006) Pharmacogenet Genomics , vol.16 , Issue.3 , pp. 151-157
    • Liou, Y.J.1    Lai, I.C.2    Lin, M.W.3    Bai, Y.M.4    Lin, C.C.5    Liao, D.L.6    Chen, J.Y.7    Lin, C.Y.8    Wang, Y.C.9
  • 35
    • 0037223482 scopus 로고    scopus 로고
    • Oxidative mechanisms and tardive dyskinesia
    • DOI 10.2165/00023210-200317010-00004
    • Lohr JB, Kuezenski R, Niculescu AB (2003) Oxidative mechanisms and tardive dyskinesia. CNS drugs 17(1):47-62 (Pubitemid 36044348)
    • (2003) CNS Drugs , vol.17 , Issue.1 , pp. 47-62
    • Lohr, J.B.1    Kuczenski, R.2    Niculescu, A.B.3
  • 36
    • 71849104860 scopus 로고
    • Protein measurements with the Folin-phenol reagent
    • Lowry OH (1951) Protein measurements with the Folin-phenol reagent. J Biol Chem 193:265-275
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1
  • 37
    • 0037370191 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine 1A receptor activation protects against N-methyl-D-aspartate-induced apoptotic cell death in striatal and mesencephalic cultures
    • DOI 10.1124/jpet.102.044370
    • Madhavan L, Freed WJ, Anantharam V, Kanthasamy AG (2003) 5- Hydroxytryptamine 1A receptor activation protects against Nmethyl- D-aspartate-induced apoptotic cell death in striatal and mesencephalic cultures. J Pharmacol Exp Ther 304(3):913-923 (Pubitemid 36254401)
    • (2003) Journal of Pharmacology and Experimental Therapeutics , vol.304 , Issue.3 , pp. 913-923
    • Madhavan, L.1    Freed, W.J.2    Anantharam, V.3    Kanthasamy, A.G.4
  • 39
    • 16544368420 scopus 로고    scopus 로고
    • Clinical implications of pharmacogenomics for tardive dyskinesia
    • DOI 10.1038/sj.tpj.6500233
    • Müller DJ, Shinkai T, De Luca V, Kennedy JL (2004) Clinical implications of pharmacogenomics for tardive dyskinesia. Pharmacogenomics J 4(2):77-87 (Pubitemid 38499990)
    • (2004) Pharmacogenomics Journal , vol.4 , Issue.2 , pp. 77-87
    • Muller, D.J.1    Shinkai, T.2    De Luca, V.3    Kennedy, J.L.4
  • 40
    • 0038030618 scopus 로고    scopus 로고
    • Quercetin, a bioflavonoid attenuated haloperidol induced orofacial dyskinesia
    • Naidu PS, Singh A, Kulkarni SK (2003) Quercetin, a bioflavonoid attenuated haloperidol induced orofacial dyskinesia. Neuropharmacology 44:1100-1106
    • (2003) Neuropharmacology , vol.44 , pp. 1100-1106
    • Naidu, P.S.1    Singh, A.2    Kulkarni, S.K.3
  • 41
    • 0032926620 scopus 로고    scopus 로고
    • Biotransformation of curcumin through reduction and glucuronidation in mice
    • Pan MH, Huang TM, Lin JK (1999) Biotransformation of curcumin through reduction and glucuronidation in mice. Drug Metab Dispos 27:486-494
    • (1999) Drug Metab Dispos , vol.27 , pp. 486-494
    • Pan, M.H.1    Huang, T.M.2    Lin, J.K.3
  • 43
    • 0032531429 scopus 로고    scopus 로고
    • Induction of NF-κB activity during haloperidol-induced oxidative toxicity in clonal hippocampal cells: Suppression of NF-κB and neuroprotection by antioxidants
    • Post A, Holsboer F, Behl C (1998) Induction of NF-KB activity during haloperidol-induced oxidative toxicity in clonal hippocampal cells: Suppression of NF-KB and neuroprotection by antioxidants. J Neurosci 15:8236-8246 (Pubitemid 28465001)
    • (1998) Journal of Neuroscience , vol.18 , Issue.20 , pp. 8236-8246
    • Post, A.1    Holsboer, F.2    Behl, C.3
  • 44
    • 0036179990 scopus 로고    scopus 로고
    • Mechanisms underlying the protective potential of α-tocopherol (vitamin E) against haloperidol-associated neurotoxicity
    • DOI 10.1016/S0893-133X(01)00364-5, PII S0893133X01003645
    • Post A, Rücker M, Ohl F, Uhr M, Holsboer F, Almeida OF, Michaelidis TM (2002) Mechanisms underlying the protective potential of alpha-tocopherol (vitamin E) against haloperidolassociated neurotoxicity. Neuropsychopharmacology 26(3):397-407 (Pubitemid 34159217)
    • (2002) Neuropsychopharmacology , vol.26 , Issue.3 , pp. 397-407
    • Post, A.1    Rucker, M.2    Ohl, F.3    Uhr, M.4    Holsboer, F.5    Almeida, O.F.X.6    Michaelidis, T.M.7
  • 46
    • 0033561799 scopus 로고    scopus 로고
    • Nuclear factor κB nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor-mediated apoptosis in rat striatum
    • Qin ZH, Chen RW, Wang Y, Nakai M, Chuang DM, Chase TN (1999) Nuclear factor KB nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor apoptosis. J Neurosci 19:4023-4033 (Pubitemid 29222275)
    • (1999) Journal of Neuroscience , vol.19 , Issue.10 , pp. 4023-4033
    • Qin, Z.-H.1    Chen, R.-W.2    Wang, Y.3    Nakai, M.4    Chuang, D.-M.5    Chase, T.N.6
  • 48
    • 33748529328 scopus 로고    scopus 로고
    • Curcumin protects mouse brain from oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydro pyridine
    • Rajeswari A (2006) Curcumin protects mouse brain from oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Eur Rev Med Pharmacol Sci 10(4):157-161 (Pubitemid 44468939)
    • (2006) European Review for Medical and Pharmacological Sciences , vol.10 , Issue.4 , pp. 157-161
    • Rajeswari, A.1
  • 49
    • 9644289344 scopus 로고    scopus 로고
    • 1A receptor agonist, 8-OH-DPAT, protects neurons and reduces astroglial reaction after ischemic damage caused by cortical devascularization
    • DOI 10.1016/j.brainres.2004.10.019, PII S0006899304016634
    • Ramos AJ, Rubio MD, Defagot C, Hischberg L, Villar MJ, Brusco A (2004) The 5HT1A receptor agonist, 8-OH-DPAT, protects neurons and reduces astroglial reaction after ischemic damage caused by cortical devascularization. Brain Res 1030(2):201-220 (Pubitemid 39574953)
    • (2004) Brain Research , vol.1030 , Issue.2 , pp. 201-220
    • Ramos, A.J.1    Rubio, M.D.2    Defagot, C.3    Hischberg, L.4    Villar, M.J.5    Brusco, A.6
  • 50
    • 0034571975 scopus 로고    scopus 로고
    • Effects of piperine on antioxidant pathways in tissues from normal and streptozotocininduced diabetic rats
    • Rauscher FM, Sanders RA, Watkins JB (2000) Effects of piperine on antioxidant pathways in tissues from normal and streptozotocininduced diabetic rats. J Biochem Mol Toxicol 14(6):329-334
    • (2000) J Biochem Mol Toxicol , vol.14 , Issue.6 , pp. 329-334
    • Rauscher, F.M.1    Sanders, R.A.2    Watkins, J.B.3
  • 51
    • 8644287505 scopus 로고    scopus 로고
    • Haloperidol and clozapine, but not olanzapine, induces oxidative stress in rat brain
    • DOI 10.1016/j.neulet.2004.09.032, PII S0304394004011668
    • Reinke A, Martins MR, Lima MS, Moreira JC, Dal-Pizzol F, Quevedo J (2004) Haloperidol and clozapine, but not olanzapine, induces oxidative stress in rat brain. Neurosci Lett 372(1-2): 157-160 (Pubitemid 39505248)
    • (2004) Neuroscience Letters , vol.372 , Issue.1-2 , pp. 157-160
    • Reinke, A.1    Martins, M.R.2    Lima, M.S.3    Moreira, J.C.4    Dal-Pizzol, F.5    Quevedo, J.6
  • 52
    • 23144441853 scopus 로고    scopus 로고
    • The role of 5-HT2C receptor polymorphisms in the pharmacogenetics of antipsychotic drug treatment
    • DOI 10.1016/j.pnpbp.2005.03.019, PII S0278584605001466
    • Reynolds GP, Templeman LA, Zhang ZJ (2005) The role of 5-HT2C receptor polymorphisms in the pharmacogenetics of antipsychotic drug treatment. Prog Neuropsychopharmacol Biol Psychiatry 29(6):1021-1028 (Pubitemid 41080129)
    • (2005) Progress in Neuro-Psychopharmacology and Biological Psychiatry , vol.29 , Issue.6 , pp. 1021-1028
    • Reynolds, G.P.1    Templeman, L.A.2    Zhang, Z.J.3
  • 53
    • 0031844208 scopus 로고    scopus 로고
    • Induction of reactive oxygen species in neurons haloperidol
    • Sagara Y (1998) Induction of reactive oxygen species in neurons by haloperidol. J Neurochem 71:1002-1012 (Pubitemid 28390254)
    • (1998) Journal of Neurochemistry , vol.71 , Issue.3 , pp. 1002-1012
    • Sagara, Y.1
  • 54
    • 33748157826 scopus 로고    scopus 로고
    • Role of nigral NFκB p50 and p65 subunit expression in haloperidol-induced neurotoxicity and stereotyped behavior in rats
    • DOI 10.1016/j.euroneuro.2006.01.001, PII S0924977X06000198
    • Saldaña M, Bonastre M, Aguilar E, Marin C (2006) Role of nigral NF-kappaB p50 and p65 subunit expression in haloperidolinduced neurotoxicity and stereotyped behavior in rats. Eur Neuropsychopharmacol 16(7):491-497 (Pubitemid 44311001)
    • (2006) European Neuropsychopharmacology , vol.16 , Issue.7 , pp. 491-497
    • Saldana, M.1    Bonastre, M.2    Aguilar, E.3    Marin, C.4
  • 55
    • 34447299398 scopus 로고    scopus 로고
    • Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane)
    • DOI 10.1016/j.freeradbiomed.2007.05.009, PII S0891584907003255
    • Sandur SK, Ichikawa H, Pandey MK, Kunnumakkara AB, Sung B, Sethi G, Aggarwal BB (2007a) Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane). Free Radic Biol Med 43(4):568-580 (Pubitemid 47058232)
    • (2007) Free Radical Biology and Medicine , vol.43 , Issue.4 , pp. 568-580
    • Sandur, S.K.1    Ichikawa, H.2    Pandey, M.K.3    Kunnumakkara, A.B.4    Sung, B.5    Sethi, G.6    Aggarwal, B.B.7
  • 56
    • 34548058841 scopus 로고    scopus 로고
    • Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism
    • DOI 10.1093/carcin/bgm123
    • Sandur SK, Pandey MK, Sung B, Ahn KS, Murakami A, Sethi G, Limtrakul P, Badmaev V, Aggarwal BB (2007b) Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. Carcinogenesis 28(8):1765-1773 (Pubitemid 47289040)
    • (2007) Carcinogenesis , vol.28 , Issue.8 , pp. 1765-1773
    • Sandur, S.K.1    Pandey, M.K.2    Sung, B.3    Ahn, K.S.4    Murakami, A.5    Sethi, G.6    Limtrakul, P.7    Badmaev, V.8    Aggarwal, B.B.9
  • 57
    • 33746849300 scopus 로고    scopus 로고
    • The relationship between intranuclear mobility of the NF-κB subunit p65 and its DNA binding affinity
    • DOI 10.1074/jbc.M511086200
    • Schaaf MJ, Willetts L, Hayes BP, Maschera B, Stylianou E, Farrow SN (2006) The relationship between intranuclear mobility of the NF-KB subunit p65 and its DNA-binding affinity. J Biol Chem 281(31):22409-22420 (Pubitemid 44181943)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.31 , pp. 22409-22420
    • Schaaf, M.J.M.1    Willetts, L.2    Hayes, B.P.3    Maschera, B.4    Stylianou, E.5    Farrow, S.N.6
  • 58
    • 0029045743 scopus 로고
    • Chronic haloperidol potentiates stimulated glutamate release in caudate putamen, but not prefrontal cortex
    • See RE, Lynch AM (1995) Chronic haloperidol potentiates stimulated glutamate release in caudate putamen, but not prefrontal cortex. Neuroreport 6(13):1795-1798
    • (1995) Neuroreport , vol.6 , Issue.13 , pp. 1795-1798
    • See, R.E.1    Lynch, A.M.2
  • 59
    • 0029589338 scopus 로고
    • Chronic haloperidol-induced changes in regional dopamine release and metabolism and neurotensin content in rats
    • DOI 10.1016/0006-8993(95)01114-5
    • See RE, Lynch AM, Aravagiri M, Nemeroff CB, Owens MJ (1995) Chronic haloperidol-induced changes in regional dopamine release and metabolism and neurotensin content in rats. Brain Res 704(2):202-209 (Pubitemid 26009941)
    • (1995) Brain Research , vol.704 , Issue.2 , pp. 202-209
    • See, R.E.1    Lynch, A.M.2    Aravagiri, M.3    Nemeroff, C.B.4    Owens, M.J.5
  • 60
    • 0037291836 scopus 로고    scopus 로고
    • Cytoprotective effect of piperine against benzo[a]pyrene induced lung cancer with reference to lipid peroxidation and antioxidant system in Swiss albino mice
    • DOI 10.1016/S0367-326X(02)00304-0, PII S0367326X02003040
    • Selvendiran K, Singh JP, Krishnan KB, Sakthisekaran D (2003) Cytoprotective effect of piperine against benzo[a]pyrene induced lung cancer with reference to lipid peroxidation and antioxidant system in Swiss albino mice. Fitoterapia 74(1-2):109-115 (Pubitemid 36287253)
    • (2003) Fitoterapia , vol.74 , Issue.1-2 , pp. 109-115
    • Selvendiran, K.1    Singh, J.P.V.2    Krishnan, K.B.3    Sakthisekaran, D.4
  • 61
    • 33747698455 scopus 로고    scopus 로고
    • Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-κB signaling pathway
    • DOI 10.1074/jbc.M602627200
    • Sethi G, Ahn KS, Sandur SK, Lin X, Chaturvedi MM, Aggarwal BB (2006) Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway. J Biol Chem 281(33):23425-23435 (Pubitemid 44274117)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.33 , pp. 23425-23435
    • Sethi, G.1    Kwang, S.A.2    Sandur, S.K.3    Lin, X.4    Chaturvedi, M.M.5    Aggarwal, B.B.6
  • 63
  • 64
    • 33947579407 scopus 로고    scopus 로고
    • Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: Participation of nitric oxide and TNF-alpha
    • DOI 10.1002/ptr.2070
    • Sharma S, Chopra K, Kulkarni SK (2007b) Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: Participation of nitric oxide and TNFalpha. Phytother Res 21(3):278-283 (Pubitemid 46479679)
    • (2007) Phytotherapy Research , vol.21 , Issue.3 , pp. 278-283
    • Sharma, S.1    Chopra, K.2    Kulkarni, S.K.3
  • 66
    • 34447523548 scopus 로고    scopus 로고
    • Role of curcumin in cancer therapy
    • DOI 10.1016/j.currproblcancer.2007.04.001, PII S0147027207000219, Role of Curcumin in Cancer Therapy
    • Shishodia S, Chaturvedi MM, Aggarwal BB (2007) Role of curcumin in cancer therapy. Curr Probl Cancer 31(4):243-305 (Pubitemid 47077491)
    • (2007) Current Problems in Cancer , vol.31 , Issue.4 , pp. 243-305
    • Shishodia, S.1    Chaturvedi, M.M.2    Aggarwal, B.B.3
  • 67
    • 0031860081 scopus 로고    scopus 로고
    • Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers
    • DOI 10.1055/s-2006-957450
    • Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS (1998) Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med 64(4): 353-356 (Pubitemid 28234275)
    • (1998) Planta Medica , vol.64 , Issue.4 , pp. 353-356
    • Shoba, G.1    Joy, D.2    Joseph, T.3    Majeed, M.4    Rajendran, R.5    Srinivas, P.S.S.R.6
  • 68
    • 18844455112 scopus 로고
    • High pressure liquid chromatographic determination of Curcumin in biological fluids
    • Singh S, Khanna M, Sarin JPS (1981) High pressure liquid chromatographic determination of Curcumin in biological fluids. Indian Drugs 18:207-209
    • (1981) Indian Drugs , vol.18 , pp. 207-209
    • Singh, S.1    Khanna, M.2    Sarin, J.P.S.3
  • 69
    • 0027984221 scopus 로고
    • Clozapine in tardive dyskinesia: Observations from human and animal model studies
    • Tamminga CA, Thaker GK, Moran M, Kakigi T, Gao XM (1994) Clozapine in tardive dyskinesia: Observations from human and animal model studies. J Clin Psychiatry 55(Suppl B):102-106 (Pubitemid 24353029)
    • (1994) Journal of Clinical Psychiatry , vol.55 , Issue.9 SUPPL. B , pp. 102-106
    • Tamminga, C.A.1    Thaker, G.K.2    Moran, M.3    Kakigi, T.4    Gao, X.-M.5
  • 70
    • 33749043629 scopus 로고    scopus 로고
    • One-electron oxidation of catecholamines generates free radicals with an in vitro toxicity correlating with their lifetime
    • DOI 10.1016/j.freeradbiomed.2006.07.009, PII S0891584906004576
    • Terland O, Almås B, Flatmark T, Andersson KK, Sørlie M (2006) One-electron oxidation of catecholamines generates free radicals with an in vitro toxicity correlating with their lifetime. Free Radic Biol Med 41(8):1266-1271 (Pubitemid 44466323)
    • (2006) Free Radical Biology and Medicine , vol.41 , Issue.8 , pp. 1266-1271
    • Terland, O.1    Almas, B.2    Flatmark, T.3    Andersson, K.K.4    Sorlie, M.5
  • 71
    • 0031695231 scopus 로고    scopus 로고
    • Markers of glutamatergic neurotransmission and oxidative stress associated with tardive dyskinesia
    • Tsai G, Goff DC, Wang RW, Flood J, Baer L, Coyle JT (1998) Markers of glutamatergic neurotransmission and oxidative stress associated with tardive dyskinesia. Am J Psychiatry 155:1207-1213 (Pubitemid 28402514)
    • (1998) American Journal of Psychiatry , vol.155 , Issue.9 , pp. 1207-1213
    • Tsai, G.1    Goff, D.C.2    Chang, R.W.3    Flood, J.4    Baer, L.5    Coyle, J.T.6
  • 72
    • 3543039998 scopus 로고    scopus 로고
    • Antioxidant efficacy of black pepper (Piper nigrum L.) and piperine in rats with high fat diet induced oxidative stress
    • DOI 10.1179/135100004225004742
    • Vijayakumar RS, Surya D, Nalini N (2004) Antioxidant efficacy of black pepper (Piper nigrum L.) and piperine in rats with high fat diet induced oxidative stress. Redox Rep 9(2):105-110 (Pubitemid 39010935)
    • (2004) Redox Report , vol.9 , Issue.2 , pp. 105-110
    • Vijayakumar, R.S.1    Surya, D.2    Nalini, N.3
  • 73
    • 0028876578 scopus 로고
    • Cytotoxic effects of sigma ligands: Sigma receptor-mediated alterations in cellular morphology and viability
    • Vilner BJ, Costa BR, Bowen WD (1995) Cytotoxic effects of sigma ligands: Sigma receptor-mediated alterations in cellular morphology and viability. J Neurosci 15:134-137
    • (1995) J Neurosci , vol.15 , pp. 134-137
    • Vilner, B.J.1    Costa, B.R.2    Bowen, W.D.3
  • 74
    • 0013914976 scopus 로고
    • Mechanism of lipid peroxide formation in animal tissues
    • Wills ED (1966) Mechanism of lipid peroxide formation in animal tissues. Biochem Jour 99:667-676
    • (1966) Biochem Jour , vol.99 , pp. 667-676
    • Wills, E.D.1
  • 76
    • 26444486974 scopus 로고    scopus 로고
    • Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats
    • DOI 10.1016/j.pbb.2005.08.009, PII S0091305705002832
    • Xu Y, Ku BS, Yao HY, Lin YH, Ma X, Zhang YH, Li XJ (2005b) Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats. Pharmacol Biochem Behav 82(1):200-206 (Pubitemid 41423504)
    • (2005) Pharmacology Biochemistry and Behavior , vol.82 , Issue.1 , pp. 200-206
    • Xu, Y.1    Ku, B.-S.2    Yao, H.-Y.3    Lin, Y.-H.4    Ma, X.5    Zhang, Y.-H.6    Li, X.-J.7
  • 77
    • 0034641936 scopus 로고    scopus 로고
    • Apoptosis in the nervous system
    • Yuan J, Yankner BA (2000) Apoptosis in the nervous system. Nature 407:802-809
    • (2000) Nature , vol.407 , pp. 802-809
    • Yuan, J.1    Yankner, B.A.2


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