Antioxidant efficacy of black pepper (Piper nigrum L.) and piperine in rats with high fat diet induced oxidative stress

Redox Report

Volumn 9, Issue 2, 2004, Pages 105-110

  Vijayakumar, R S ^a   Surya, D ^a   Nalini, N ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Black pepper; High fat diet; Oxidative stress; Piperine

Indexed keywords

ALKADIENE; BILE SALT; CATALASE; CHOLESTEROL; COCONUT OIL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; PIPERINE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AORTA; ARTICLE; BLACK PEPPER; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG EFFICACY; DRUG ISOLATION; ENZYME ACTIVITY; HEART; INTESTINE; KIDNEY; LIPID DIET; LIPID PEROXIDATION; LIVER; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

ALKALOIDS; ANIMALS; ANTIOXIDANTS; AORTA; BENZODIOXOLES; CATALASE; DIETARY FATS; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HEART; INTESTINES; KIDNEY; LIPID PEROXIDATION; LIVER; MALE; OXIDATIVE STRESS; PIPER NIGRUM; PIPERIDINES; POLYUNSATURATED ALKAMIDES; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

FELIS CATUS; PIPER NIGRUM; RATTUS NORVEGICUS;

EID: 3543039998     PISSN: 13510002     EISSN: None     Source Type: Journal    
DOI: 10.1179/135100004225004742     Document Type: Article

References (29)

1. Young IS, Woodside JV. Antioxidants in health and disease. J Clin Pathol 2001; 54: 176-186.
2. Beckman KB, Ames BN. The free radical theory of aging matures. Physiol Rev 1998; 78: 547-581.
3. Yu BP. Aging and oxidative stress: modulation by dietary restriction. Free Radic Biol Med 1996; 21: 651-668.
4. Vladimirov Yu, Parfenov E, Epanchintseva O, Smirnov LD. Antiradical activity of coumarin reductones. Byull Ekspermen Biol Med 1991; 112: 475-478.
5. Lee EB, Shin KH, Woo WS. Pharmacological study on piperine. Arch Pharmacol Res 1984; 7: 127-132.
6. Allameh A, Saxena M, Biswas G, Raj HG, Singh J, Srivastava N. Piperine, a plant alkaloid of the piper species, enhances the bioavailability of aflatoxin B1 in rat tissues. Cancer Lett 1992; 61: 195-199.
7. Khajuria A, Thusu N, Zutshi U. Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: influence on brush border membrane fluidity, ultrastructure and enzyme kinetics. Phytomedicine 2002; 9: 224-231.
8. Kawada T, Sakabe S. Some pungent principles of spices cause the adrenal medulla to secrete catecholamines in anesthetized rats. Proc Soc Exp Biol Med 1988; 188: 229-233.
9. Tripathi P, Tripathi GS. Thyrogenic response of Piper nigrum. Fitoterapia 1989; 60: 539-542.
10. Thimmayamma BVS, Rao P, Radhaiah G. Seasonal changes in consumption of food by Indians. Indian J Nutr Diet 1983; 20: 153-162.
11. Donnan SK. The thiobarbituric acid test applied to tissues from rats treated in various ways. J Biol Chem 1950; 182: 415-419.
12. Beuje JA, Aust SD. Microsomal lipid peroxidation. Methods Enzymol 1978; 52: 302-310.
13. Kakkar P, Das B, Viswanathan PN. A modified spectrophotometric assay of SOD. Indian J Biochem Biophys 1984; 21: 130-132.
14. Sinha AK. Colorimetric assay of catalase. Anal Biochem 1972; 47: 389-394.
15. Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hateman DG, Hoekstra WG. Selenium: biochemical role as a component of glutathione peroxidase. Science 1973; 179: 588-590.
16. Habig WH, Pabst MJ, Jakoby WB. Glutathione-S-transferases, the first enzymatic step in mercapturic acid formation. J Biol Chem 1974; 249: 7130-7139.
17. Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophys 1959; 82: 70-77.
18. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with Folin phenol reagent. J Biol Chem 1951; 193: 265-275.
19. Chou YH. Experimental design and the analysis of variance. In: Chou YH (ed) Statistical Analysis-I. New York: Holt, Reinhart and Winston Publications, 1975; 340-352.
20. De Zwart L, Meerman J. Biomarkers of free radical damage applications in experimental animals and in humans. Free Radic Biol Med 1998; 26: 202-206.
21. Kasapoglu M, Ozben T. Alterations of antioxidant enzymes and oxidative stress markers in aging. Exp Gerontol 2001; 36: 209-220.
22. Khan BA, Abraham A, Leelamma S. Antioxidant effects of curry leaf, Murraya koenigii and mustard seeds, Brassica juncea in rats fed with high fat diet. Indian J Exp Biol 1997; 35: 148-150.
23. Jeyakumar SM, Nalini N, Menon VP. Antioxidant activity of ginger (Zingiber officinale Rosc.) in rats fed a high fat diet. Med Sci Res 1999; 27: 341-344.
24. Fang YZ, Yang S, Wu G. Free radicals, antioxidants, and nutrition. Nutrition 2002; 18: 872-879.
25. Shobana S, Naidu KA. Antioxidant activity of selected Indian spices. Prostaglandins Leukot Essent Fatty Acids 2000; 62: 107-110.
26. Mittal R, Gupta RL. In vitro antioxidant activity of piperine. Methods Find Exp Clin Pharmacol 2000; 22: 271-274.
27. Dhuley JN, Raman PH, Mujumdar AM, Naik SR. Inhibition of lipid peroxidation by piperine during experimental inflammation in rats. Indian J Exp Biol 1993; 31: 443-3445.
28. Koul IB, Kapil A. Evaluation of the liver protective potential of piperine, an active principle of black and long peppers. Planta Med 1993; 59: 413-417.
29. Rauscher FM, Sanders RA, Watkins JB. Effects of piperine on antioxidant pathways in tissues from normal and streptozotocin-induced diabetic rats. J Biochem Mol Toxicol 2000; 14: 329-334.