-
1
-
-
8644284227
-
Adult Burkitt leukemia and lymphoma
-
Blum, K. A., Lozanski, G., & Byrd, J. C. (2004). Adult Burkitt leukemia and lymphoma. Blood, 104, 3009-3020.
-
(2004)
Blood
, vol.104
, pp. 3009-3020
-
-
Blum, K.A.1
Lozanski, G.2
Byrd, J.C.3
-
2
-
-
0025132245
-
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
-
Issemann, I., & Green, S. (1990). Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature, 347, 645-650.
-
(1990)
Nature
, vol.347
, pp. 645-650
-
-
Issemann, I.1
Green, S.2
-
3
-
-
0036043445
-
Role of the peroxisome proliferator-activated receptors (PPARS) in the regulation of lipids and inflammation control
-
Bocher, V., Chinetti, G., Fruchart, J. C., & Staels, B. (2002). Role of the peroxisome proliferator-activated receptors (PPARS) in the regulation of lipids and inflammation control. Journal of Social Biology, 196, 47-52.
-
(2002)
Journal of Social Biology
, vol.196
, pp. 47-52
-
-
Bocher, V.1
Chinetti, G.2
Fruchart, J.C.3
Staels, B.4
-
4
-
-
35048833701
-
The potential of peroxisome proliferator-activated receptor gamma (PPARgamma) ligands in the treatment of hematological malignancies
-
Ulivieri, C., & Baldari, C. T. (2007). The potential of peroxisome proliferator-activated receptor gamma (PPARgamma) ligands in the treatment of hematological malignancies. Mini Reviews in Medicinal Chemistry, 7, 877-887.
-
(2007)
Mini Reviews in Medicinal Chemistry
, vol.7
, pp. 877-887
-
-
Ulivieri, C.1
Baldari, C.T.2
-
5
-
-
33644954823
-
Peroxisome proliferator-activated receptor gamma in malignant diseases
-
Wang, T., Xu, J., Yu, X., Yang, R., & Han, Z. C. (2006). Peroxisome proliferator-activated receptor gamma in malignant diseases. Critical Reviews in Oncology/Hematology, 58, 1-14.
-
(2006)
Critical Reviews in Oncology/Hematology
, vol.58
, pp. 1-14
-
-
Wang, T.1
Xu, J.2
Yu, X.3
Yang, R.4
Han, Z.C.5
-
6
-
-
0033998334
-
The PPARs: From orphan receptors to drug discovery
-
Willson, T. M., Brown, P. J., Sternbach, D. D., & Henke, B. R. (2000). The PPARs: From orphan receptors to drug discovery. Journal of Medicinal Chemistry, 43, 527-550.
-
(2000)
Journal of Medicinal Chemistry
, vol.43
, pp. 527-550
-
-
Willson, T.M.1
Brown, P.J.2
Sternbach, D.D.3
Henke, B.R.4
-
7
-
-
7444239080
-
Peroxisome proliferator-activated receptor gamma and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias
-
Konopleva, M., Elstner, E., McQueen, T. J., Tsao, T., Sudarikov, A., et al. (2004). Peroxisome proliferator-activated receptor gamma and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias. Molecular Cancer Therapeutics, 3, 1249-1262.
-
(2004)
Molecular Cancer Therapeutics
, vol.3
, pp. 1249-1262
-
-
Konopleva, M.1
Elstner, E.2
McQueen, T.J.3
Tsao, T.4
Sudarikov, A.5
-
8
-
-
33646430295
-
Growth inhibition and apoptosis in human Philadelphia chromosome-positive lymphoblastic leukemia cell lines by treatment with the dual PPARalpha/gamma ligand TZD18
-
Liu, H., Zang, C., Fenner, M. H., Liu, D., Possinger, K., et al. (2006). Growth inhibition and apoptosis in human Philadelphia chromosome-positive lymphoblastic leukemia cell lines by treatment with the dual PPARalpha/gamma ligand TZD18. Blood, 107, 3683-3692.
-
(2006)
Blood
, vol.107
, pp. 3683-3692
-
-
Liu, H.1
Zang, C.2
Fenner, M.H.3
Liu, D.4
Possinger, K.5
-
9
-
-
33749506249
-
The peroxisome proliferator-activated receptor gamma (PPARgamma) ligands 15-deoxy-Delta12, 14-prostaglandin J2 and ciglitazone induce human B lymphocyte and B cell lymphoma apoptosis by PPARgamma-independent mechanisms
-
Ray, D. M., Akbiyik, F., & Phipps, R. P. (2006). The peroxisome proliferator-activated receptor gamma (PPARgamma) ligands 15-deoxy-Delta12, 14-prostaglandin J2 and ciglitazone induce human B lymphocyte and B cell lymphoma apoptosis by PPARgamma-independent mechanisms. Journal of Immunology, 177, 5068-5076.
-
(2006)
Journal of Immunology
, vol.177
, pp. 5068-5076
-
-
Ray, D.M.1
Akbiyik, F.2
Phipps, R.P.3
-
10
-
-
42549137968
-
PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL
-
Tabe, Y., Konopleva, M., Kondo, Y., Contractor, R., Tsao, T., et al. (2007). PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL. Cancer Biology & Therapy, 6, 1967-1977.
-
(2007)
Cancer Biology & Therapy
, vol.6
, pp. 1967-1977
-
-
Tabe, Y.1
Konopleva, M.2
Kondo, Y.3
Contractor, R.4
Tsao, T.5
-
11
-
-
46449112610
-
A phase I study of bexarotene and rosiglitazone in patients with refractory cancers
-
Read, W. L., Baggstrom, M. Q., Fracasso, P. M., & Govindan, R. (2008). A phase I study of bexarotene and rosiglitazone in patients with refractory cancers. Chemotherapy, 54, 236-241.
-
(2008)
Chemotherapy
, vol.54
, pp. 236-241
-
-
Read, W.L.1
Baggstrom, M.Q.2
Fracasso, P.M.3
Govindan, R.4
-
12
-
-
77956264304
-
The embryonic transcription cofactor LBH is a direct target of the Wnt signaling pathway in epithelial development and in aggressive basal subtype breast cancers
-
Rieger, M. E., Sims, A. H., Coats, E. R., Clarke, R. B., & Briegel, K. J. (2010). The embryonic transcription cofactor LBH is a direct target of the Wnt signaling pathway in epithelial development and in aggressive basal subtype breast cancers. Molecular and Cellular Biology, 30, 4267-4279.
-
(2010)
Molecular and Cellular Biology
, vol.30
, pp. 4267-4279
-
-
Rieger, M.E.1
Sims, A.H.2
Coats, E.R.3
Clarke, R.B.4
Briegel, K.J.5
-
13
-
-
27844516613
-
Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins
-
Liu, X., Rubin, J. S., & Kimmel, A. R. (2005). Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins. Current Biology, 15, 1989-1997.
-
(2005)
Current Biology
, vol.15
, pp. 1989-1997
-
-
Liu, X.1
Rubin, J.S.2
Kimmel, A.R.3
-
14
-
-
65449133183
-
Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta)-mediated signal transduction pathway: Inhibitors of the Wnt/beta-catenin signaling pathway as novel anticancer drugs
-
Takahashi-Yanaga, F., & Sasaguri, T. (2009). Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta)-mediated signal transduction pathway: Inhibitors of the Wnt/beta-catenin signaling pathway as novel anticancer drugs. J Pharmacol Sci, 109, 179-183.
-
(2009)
J Pharmacol Sci
, vol.109
, pp. 179-183
-
-
Takahashi-Yanaga, F.1
Sasaguri, T.2
-
15
-
-
4344619713
-
Pharmacological inhibitors of glycogen synthase kinase 3
-
Meijer, L., Flajolet, M., & Greengard, P. (2004). Pharmacological inhibitors of glycogen synthase kinase 3. Trends in Pharmacological Sciences, 25, 471-480.
-
(2004)
Trends in Pharmacological Sciences
, vol.25
, pp. 471-480
-
-
Meijer, L.1
Flajolet, M.2
Greengard, P.3
-
16
-
-
77952954695
-
When pathways collide: Collaboration and connivance among signalling proteins in development
-
McNeill, H., & Woodgett, J. R. (2010). When pathways collide: Collaboration and connivance among signalling proteins in development. Nature Reviews Molecular Cell Biology, 11, 404-413.
-
(2010)
Nature Reviews Molecular Cell Biology
, vol.11
, pp. 404-413
-
-
McNeill, H.1
Woodgett, J.R.2
-
17
-
-
67649842389
-
Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown
-
Sopko, R., Silva, E., Clayton, L., Gardano, L., Barrios-Rodiles, M., et al. (2009). Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown. Current Biology, 19, 1112-1117.
-
(2009)
Current Biology
, vol.19
, pp. 1112-1117
-
-
Sopko, R.1
Silva, E.2
Clayton, L.3
Gardano, L.4
Barrios-Rodiles, M.5
-
18
-
-
33750624298
-
The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway
-
Silva, E., Tsatskis, Y., Gardano, L., Tapon, N., & McNeill, H. (2006). The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway. Current Biology, 16, 2081-2089.
-
(2006)
Current Biology
, vol.16
, pp. 2081-2089
-
-
Silva, E.1
Tsatskis, Y.2
Gardano, L.3
Tapon, N.4
McNeill, H.5
-
19
-
-
34447646653
-
Wnt signaling as a therapeutic target for cancer
-
Herbst, A., & Kolligs, F. T. (2007). Wnt signaling as a therapeutic target for cancer. Methods in Molecular Biology, 361, 63-91.
-
(2007)
Methods in Molecular Biology
, vol.361
, pp. 63-91
-
-
Herbst, A.1
Kolligs, F.T.2
-
20
-
-
0037737728
-
A role for Wnt signalling in self-renewal of haematopoietic stem cells
-
Reya, T., Duncan, A. W., Ailles, L., Domen, J., Scherer, D. C., et al. (2003). A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature, 423, 409-414.
-
(2003)
Nature
, vol.423
, pp. 409-414
-
-
Reya, T.1
Duncan, A.W.2
Ailles, L.3
Domen, J.4
Scherer, D.C.5
-
21
-
-
34147190412
-
Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia
-
Roman-Gomez, J., Cordeu, L., Agirre, X., Jimenez-Velasco, A., San Jose-Eneriz, E., et al. (2007). Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia. Blood, 109, 3462-3469.
-
(2007)
Blood
, vol.109
, pp. 3462-3469
-
-
Roman-Gomez, J.1
Cordeu, L.2
Agirre, X.3
Jimenez-Velasco, A.4
San, J.-E.E.5
-
22
-
-
36349013133
-
Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma
-
Chim, C. S., Pang, R., Fung, T. K., Choi, C. L., & Liang, R. (2007). Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma. Leukemia, 21, 2527-2536.
-
(2007)
Leukemia
, vol.21
, pp. 2527-2536
-
-
Chim, C.S.1
Pang, R.2
Fung, T.K.3
Choi, C.L.4
Liang, R.5
-
23
-
-
42349115929
-
Peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses colonic epithelial cell turnover and colon carcinogenesis through inhibition of the beta-catenin/T cell factor (TCF) pathway
-
Fujisawa, T., Nakajima, A., Fujisawa, N., Takahashi, H., Ikeda, I., et al. (2008). Peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses colonic epithelial cell turnover and colon carcinogenesis through inhibition of the beta-catenin/T cell factor (TCF) pathway. Journal of Pharmacological Sciences, 106, 627-638.
-
(2008)
Journal of Pharmacological Sciences
, vol.106
, pp. 627-638
-
-
Fujisawa, T.1
Nakajima, A.2
Fujisawa, N.3
Takahashi, H.4
Ikeda, I.5
-
24
-
-
11244253710
-
GW9662, a potent antagonist of PPARgamma, inhibits growth of breast tumour cells and promotes the anticancer effects of the PPARgamma agonist rosiglitazone, independently of PPARgamma activation
-
Seargent, J. M., Yates, E. A., & Gill, J. H. (2004). GW9662, a potent antagonist of PPARgamma, inhibits growth of breast tumour cells and promotes the anticancer effects of the PPARgamma agonist rosiglitazone, independently of PPARgamma activation. British Journal of Pharmacology, 143, 933-937.
-
(2004)
British Journal of Pharmacology
, vol.143
, pp. 933-937
-
-
Seargent, J.M.1
Yates, E.A.2
Gill, J.H.3
-
25
-
-
34247165867
-
Peroxisome proliferator-activated receptor-gamma antagonists exhibit potent antiproliferative effects versus many hematopoietic and epithelial cancer cell lines
-
Burton, J. D., Castillo, M. E., Goldenberg, D. M., & Blumenthal, R. D. (2007). Peroxisome proliferator-activated receptor-gamma antagonists exhibit potent antiproliferative effects versus many hematopoietic and epithelial cancer cell lines. Anticancer Drugs, 18, 525-534.
-
(2007)
Anticancer Drugs
, vol.18
, pp. 525-534
-
-
Burton, J.D.1
Castillo, M.E.2
Goldenberg, D.M.3
Blumenthal, R.D.4
-
26
-
-
33947324058
-
PPARgamma activation by thiazolidinediones (TZDs) may modulate breast carcinoma outcome: The importance of interplay with TGFbeta signalling
-
Jarrar, M. H., & Baranova, A. (2007). PPARgamma activation by thiazolidinediones (TZDs) may modulate breast carcinoma outcome: The importance of interplay with TGFbeta signalling. J Cell Mol Med, 11, 71-87.
-
(2007)
J Cell Mol Med
, vol.11
, pp. 71-87
-
-
Jarrar, M.H.1
Baranova, A.2
-
27
-
-
0042470614
-
H. pylori infection, atrophic gastritis, cytokines, gastrin, COX-2, PPAR gamma and impaired apoptosis in gastric carcinogenesis
-
Konturek, P. C., Kania, J., Konturek, J. W., Nikiforuk, A., Konturek, S. J., et al. (2003). H. pylori infection, atrophic gastritis, cytokines, gastrin, COX-2, PPAR gamma and impaired apoptosis in gastric carcinogenesis. Medical Science Monitor, 9, SR53-SR66.
-
(2003)
Medical Science Monitor
, vol.9
-
-
Konturek, P.C.1
Kania, J.2
Konturek, J.W.3
Nikiforuk, A.4
Konturek, S.J.5
-
28
-
-
36549051626
-
PPARgamma physiology and pathology in gastrointestinal epithelial cells
-
Thompson, E. A. (2007). PPARgamma physiology and pathology in gastrointestinal epithelial cells. Molecules and Cells, 24, 167-176.
-
(2007)
Molecules and Cells
, vol.24
, pp. 167-176
-
-
Thompson, E.A.1
-
29
-
-
77950922596
-
The role of the PAX8/PPARgamma fusion oncogene in the pathogenesis of follicular thyroid cancer
-
Eberhardt, N. L., Grebe, S. K., McIver, B., & Reddi, H. V. (2010). The role of the PAX8/PPARgamma fusion oncogene in the pathogenesis of follicular thyroid cancer. Molecular and Cellular Endocrinology, 321, 50-56.
-
(2010)
Molecular and Cellular Endocrinology
, vol.321
, pp. 50-56
-
-
Eberhardt, N.L.1
Grebe, S.K.2
McIver, B.3
Reddi, H.V.4
-
30
-
-
43549100859
-
A gut feeling of the PXR, PPAR and NF-kappaB connection
-
Wahli, W. (2008). A gut feeling of the PXR, PPAR and NF-kappaB connection. Journal of Internal Medicine, 263, 613-619.
-
(2008)
Journal of Internal Medicine
, vol.263
, pp. 613-619
-
-
Wahli, W.1
-
32
-
-
58849143927
-
Peroxisome proliferator-activated receptor gamma pathway targeting in carcinogenesis: Implications for chemoprevention
-
Ondrey, F. (2009). Peroxisome proliferator-activated receptor gamma pathway targeting in carcinogenesis: Implications for chemoprevention. Clinical Cancer Research, 15, 2-8.
-
(2009)
Clinical Cancer Research
, vol.15
, pp. 2-8
-
-
Ondrey, F.1
-
33
-
-
17444363390
-
Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species
-
Chen, Y. C., Shen, S. C., & Tsai, S. H. (2005). Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species. Biochimica et Biophysica Acta, 1743, 291-304.
-
(2005)
Biochimica Et Biophysica Acta
, vol.1743
, pp. 291-304
-
-
Chen, Y.C.1
Shen, S.C.2
Tsai, S.H.3
-
34
-
-
7444241538
-
The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia
-
Konopleva, M., Tsao, T., Estrov, Z., Lee, R. M., Wang, R. Y., et al. (2004). The synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia. Cancer Research, 64, 7927-7935.
-
(2004)
Cancer Research
, vol.64
, pp. 7927-7935
-
-
Konopleva, M.1
Tsao, T.2
Estrov, Z.3
Lee, R.M.4
Wang, R.Y.5
-
35
-
-
20144387787
-
Expression of survivin and bax/bcl-2 in peroxisome proliferator activated receptor-gamma ligands induces apoptosis on human myeloid leukemia cells in vitro
-
Liu, J. J., Huang, R. W., Lin, D. J., Peng, J., Wu, X. Y., et al. (2005). Expression of survivin and bax/bcl-2 in peroxisome proliferator activated receptor-gamma ligands induces apoptosis on human myeloid leukemia cells in vitro. Annals of Oncology, 16, 455-459.
-
(2005)
Annals of Oncology
, vol.16
, pp. 455-459
-
-
Liu, J.J.1
Huang, R.W.2
Lin, D.J.3
Peng, J.4
Wu, X.Y.5
-
36
-
-
23244448038
-
Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells
-
Liu, J., Lu, H., Huang, R., Lin, D., Wu, X., et al. (2005). Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells. Cancer Chemotherapy and Pharmacology, 56, 400-408.
-
(2005)
Cancer Chemotherapy and Pharmacology
, vol.56
, pp. 400-408
-
-
Liu, J.1
Lu, H.2
Huang, R.3
Lin, D.4
Wu, X.5
-
37
-
-
20444399144
-
Cancer prevention by retinoids and carotenoids: Independent action on a common target
-
Bertram, J. S., & Vine, A. L. (2005). Cancer prevention by retinoids and carotenoids: Independent action on a common target. Biochimica et Biophysica Acta, 1740, 170-178.
-
(2005)
Biochimica Et Biophysica Acta
, vol.1740
, pp. 170-178
-
-
Bertram, J.S.1
Vine, A.L.2
-
38
-
-
53149108942
-
Docosahexaenoic acid sensitizes Ramos cells to Gamma-irradiation-induced apoptosis through involvement of PPAR-gamma activation and NF-kappaB suppression
-
Zand, H., Rahimipour, A., Salimi, S., & Shafiee, S. M. (2008). Docosahexaenoic acid sensitizes Ramos cells to Gamma-irradiation-induced apoptosis through involvement of PPAR-gamma activation and NF-kappaB suppression. Molecular and Cellular Biochemistry, 317, 113-120.
-
(2008)
Molecular and Cellular Biochemistry
, vol.317
, pp. 113-120
-
-
Zand, H.1
Rahimipour, A.2
Salimi, S.3
Shafiee, S.M.4
-
39
-
-
77952669603
-
Repression of beta-catenin signaling by PPAR gamma ligands
-
Lu, D., & Carson, D. A. (2010). Repression of beta-catenin signaling by PPAR gamma ligands. European Journal of Pharmacology, 636, 198-202.
-
(2010)
European Journal of Pharmacology
, vol.636
, pp. 198-202
-
-
Lu, D.1
Carson, D.A.2
-
40
-
-
36749036044
-
Knocking the Wnt out of the sails of leukemia stem cell development
-
Deshpande, A. J., & Buske, C. (2007). Knocking the Wnt out of the sails of leukemia stem cell development. Cell Stem Cell, 1, 597-598.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 597-598
-
-
Deshpande, A.J.1
Buske, C.2
-
41
-
-
18344390234
-
Gene expression profile of adipocyte differentiation and its regulation by peroxisome proliferator-activated receptor-gamma agonists
-
Gerhold, D. L., Liu, F., Jiang, G., Li, Z., Xu, J., et al. (2002). Gene expression profile of adipocyte differentiation and its regulation by peroxisome proliferator-activated receptor-gamma agonists. Endocrinology, 143, 2106-2118.
-
(2002)
Endocrinology
, vol.143
, pp. 2106-2118
-
-
Gerhold, D.L.1
Liu, F.2
Jiang, G.3
Li, Z.4
Xu, J.5
|