Electromagnetic hypersensitivity: Fact or fiction?

Science of the Total Environment

Volumn 414, Issue , 2012, Pages 103-112

  Genuis, Stephen J ^a   Lipp, Christopher T ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Cell phones; EHS; Electro sensitivity; Electromagnetic hypersensitivity; Electromagnetic radiation; Sensitivity related illness; Wireless

Indexed keywords

CELL PHONE; EHS; ELECTRO-SENSITIVITY; ELECTROMAGNETIC HYPERSENSITIVITY; SENSITIVITY-RELATED ILLNESS;

ELECTROMAGNETIC WAVE EMISSION; ELECTROMAGNETIC WAVES; HEALTH; PATIENT MONITORING; RADIO;

ELECTROMAGNETISM;

CATECHOLAMINE; DNA;

ELECTROMAGNETIC RADIATION; HEALTH IMPACT; SENSITIVITY ANALYSIS; TELECOMMUNICATION;

CHRONIC FATIGUE SYNDROME; DETOXIFICATION; DNA REPLICATION; ELECTRICAL EQUIPMENT; ELECTROMAGNETIC HYPERSENSITIVITY; ELECTROMAGNETIC RADIATION; FIBROMYALGIA; HUMAN; MULTIPLE CHEMICAL SENSITIVITY; PATIENT CARE PLANNING; PRIORITY JOURNAL; QUALITY OF LIFE; RADIATION EXPOSURE; RADIATION SICKNESS; REVIEW; RISK REDUCTION; WIRELESS COMMUNICATION;

BIOLOGICAL MARKERS; COMPUTER COMMUNICATION NETWORKS; ELECTROMAGNETIC FIELDS; ELECTROMAGNETIC RADIATION; HUMANS; HYPERSENSITIVITY; QUALITY OF LIFE;

EID: 84855527902     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2011.11.008     Document Type: Review

References (99)

1. Angell M. Is academic medicine for sale?. N Engl J Med 2000, 342(20):1516-1518.
2. Ashford N., Miller C. Chemical exposures: low levels and high stakes 1998, John Wiley and Sons, New York. 2nd ed.
3. Berlucchi G. Brain plasticity and cognitive neurorehabilitation. Neuropsychol Rehabil 2011, 1-19.
4. Brenner D.J., et al. Cancer risks attributable to low doses of ionizing radiation: assessing what we really know. Proc Natl Acad Sci USA 2003, 100(24):13761-13766.
5. Brodeur, P., The Zapping of America: Microwaves, Their Deadly Risk, and the Coverup. London: WW. Norton & Co.: 1977; p. 1-343.
6. Buchner K., Eger H. Changes of clinically important neurotransmitters under the influence of modulated RF fields - a long-term study under real-life conditions. Umwelt-Medizin-Gesellschaft 2011, 24(1):44-57.
7. Chemical Sensitivity Network, Platform created by WHO in order to get an ICD code for MCS and EHS [accessed July 31,2011 at ]. 2011. http://www.csn-deutschland.de/blog/en/platform-created-by-who-in-order-to-get-an-icd-code-for-mcs-and-ehs/.
8. Chevalier, G., Sinatra, ST., Oschman, JL., Sokal, K., Sokal, P. Earthing: health implications of reconnecting the human body to the earth's surface electrons. J Environ Public Health. in press.
9. Cioni G., D'Acunto G., Guzzetta A. Perinatal brain damage in children: neuroplasticity, early intervention, and molecular mechanisms of recovery. Prog Brain Res 2011, 189:139-154.
10. Costa A., et al. Heavy metals exposure and electromagnetic hypersensitivity. Sci Total Environ 2010, 408(20):4919-4920. author reply 4921.
11. Coyle B. Use of filters to treat visual-perception problem creates adherents and sceptics. CMAJ: Can Med Assoc J 1995, 152(5):749-750.
12. Dabrowski M.P., et al. Immunotropic effects in cultured human blood mononuclear cells pre-exposed to low-level 1300MHz pulse-modulated microwave field. Electromagn Biol Med 2003, 22(1):1-13.
13. Dahmen N., Ghezel-Ahmadi D., Engel A. Blood laboratory findings in patients suffering from self-perceived electromagnetic hypersensitivity (EHS). Bioelectromagnetics 2009, 30(4):299-306.
14. Das-Munshi J., Rubin G.J., Wessely S. Multiple chemical sensitivities: a systematic review of provocation studies. J Allergy Clin Immunol 2006, 118(6):1257-1264.
15. DeMatteo B. Terminal shock: the health hazards of video display terminals 1985, 1-239. NC Press, Raleigh.
16. De Luca C., et al. Biological definition of multiple chemical sensitivity from redox state and cytokine profiling and not from polymorphisms of xenobiotic-metabolizing enzymes. Toxicol Appl Pharmacol 2010, 248:285-292.
17. de Pomerai D., et al. Non-thermal heat-shock response to microwaves. Nature 2000, 405(6785):417-418.
18. Dode A.C., et al. Mortality by neoplasia and cellular telephone base stations in the Belo Horizonte municipality, Minas Gerais state, Brazil. Sci Total Environ 2011, 409(19):3649-3665.
19. Dode A.C. Dirty electricity, cellular telephone base stations and neoplasia. Sci Total Environ 2011.
20. Doherty S. History of evidence-based medicine. Oranges, chloride of lime and leeches: barriers to teaching old dogs new tricks. Emerg Med Australas 2005, 17(4):314-321.
21. Duramad P., Tager I.B., Holland N.T. Cytokines and other immunological biomarkers in children's environmental health studies. Toxicol Lett 2007, 172(1-2):48-59.
22. D'Andrea J.A., et al. Microwave effects on the nervous system. Bioelectromagnetics 2003, (Suppl 6):S107-S147.
23. Floderus B., Stenlund C., Carlgren F. Occupational exposures to high frequency electromagnetic fields in the intermediate range (>300Hz-10MHz). Bioelectromagnetics 2002, 23(8):568-577.
24. Frey A., Seifert E. Pulse modulated UHF energy illumination of the heart associated with change in heart rate. Life Sci 1968, 7(Part II):505-512.
25. Frey A. Cardiac and neural effects of modulated RF energy. Proceedings of the 23rd Annual Conference on Engineering in Medicine and Biology 1970, 12:175.
26. Frick U., et al. Comparison perception of singular transcranial magnetic stimuli by subjectively electrosensitive subjects and general population controls. Bioelectromagnetics 2005, 26(4):287-298.
27. Gangi S., Johansson O. A theoretical model based upon mast cells and histamine to explain the recently proclaimed sensitivity to electric and/or magnetic fields in humans. Med Hypotheses 2000, 54:663-671.
28. Genuis S.J. Fielding a current idea: exploring the public health impact of electromagnetic radiation. Public Health 2008, 122:113-124.
29. Genuis S.J. Sensitivity-related illness: the escalating pandemic of allergy, food intolerance and chemical sensitivity. Sci Total Environ 2010, 408(24):6047-6061.
30. Genuis S. What's out there making us sick?. J Environ Public Health 2012, doi:10.1155/2012/605137.
31. Genuis S.J. Human detoxification of perfluorinated compounds. Public Health 2010, 124(7):367-375.
32. Genuis S.J. Elimination of persistent toxicants from the human body. Hum Exp Toxicol 2011, 30(1):3-18.
33. Genuis S.K., Genuis S.J. Exploring the continuum: medical information to effective clinical practice: Paper 1. The translation of knowledge into clinical practice. J Eval Clin Pract 2006, 12:49-62.
34. Glaser, Z., Cumulated index to the Bibliography of reported biological phenomena ("effects") and clinical manifestations attributed to microwave and radio-frequency radiation: report, supplements (no. 1-9), BEMS newsletter (B-1 through B-464), 1971-1981 - Indexed by Julie Moore, Riverside, CA: Julie Moore & Associates, 1984.
35. Grol R., Grimshaw J. From best evidence to best practice: effective implementation of change in patients' care. Lancet 2003, 362(9391):1225-1230.
36. Grupo Medico Juridico, La hipersensibilidad a las ondas que producen los teléfonos móviles se convierte en una nueva causa de incapacidad permanente. Accessed on October 18th 2011 at [#]. 2011. http://www.noticiasmedicas.es/medicina/noticias/10451/1/La-hipersensibilidad-a-las-ondas-que-producen-los-telefonos-moviles-se-convierte-en-una-nueva-causa-de-incapacidad-permanente/Page1.html.
37. Hallberg O., Oberfeld G. Letter to the editor: will we all become electrosensitive?. Electromagn Biol Med 2006, 25(3):189-191.
38. Hallberg O., Johansson O. Sleep on the right side-Get cancer on the left?. Pathophysiology: The official journal of the International Society for Pathophysiology/ISP 2010, 17(3):157-160.
39. Hardell L., et al. Increased concentrations of certain persistent organic pollutants in subjects with self-reported electromagnetic hypersensitivity - a pilot study. Electromagn Biol Med 2008, 27(2):197-203.
40. Havas M. Biological effects of non-ionizing electromagnetic energy: a critical review of the reports by the US National Research Council and the US National Institute of Environmental Health Sciences as they relate to the broad realm of EMF bioeffects. Environ Rev 2000, 8:173-253.
41. Havas M. Electromagnetic hypersensitivity: biological effects of dirty electricity with emphasis on diabetes and multiple sclerosis. Electromagn Biol Med 2006, 25(4):259-268.
42. Havas M., et al. Provocation study using heart rate variability shows microwave radiation from DECT phone affects atunomic nervous system. National Institute for the Study and Control of Cancer and Environmental Disease 2010, 149-156:273-300. Mattioli, Bologna, 2010. 2010. L. Giuliani, M. Soffritti (Eds.).
43. Hillert L., et al. Cognitive behavioural therapy for patients with electric sensitivity - a multidisciplinary approach in a controlled study. Psychother Psychosom 1998, 67(6):302-310.
44. Hillert L., et al. Prevalence of self-reported hypersensitivity to electric or magnetic fields in a population-based questionnaire survey. Scand J Work Environ Health 2002, 28(1):33-41.
45. Hobbs A. Sleep-powered wellness 2011, Bold World Books, Calgary.
46. Hooper, A., Dynamic Neural Retraining System. Accessed October 18, 2011, at []. 2011. http://www.dnrsystem.com/.
47. Infas Institut für angewandte Sozialwissenschaft GmbH Ermittlungen der Befürchtungen und Ängste der breiten Öffentlichkeit hinsichtlich möglicher Gefahren der hochfrequenten elektromagnetischen Felder des Mobilfunks - jährliche Umfragen 2003, 1-34. Institut für angewandte Sozialwissenschaft GmbH, Bonn. B. trahlenschutz (Ed.).
48. Johansson O. Electrohypersensitivity: state-of-the-art of a functional impairment. Electromagn Biol Med 2006, 25(4):245-258.
49. Johansson O., et al. Cutaneous mast cells are altered in normal healthy volunteers sitting in front of ordinary TVs/PCs - results from open-field provocation experiments. J Cutan Pathol 2001, 28:513-519.
50. Johansson A., et al. Symptoms, personality traits, and stress in people with mobile phone-related symptoms and electromagnetic hypersensitivity. J Psychosom Res 2010, 68(1):37-45.
51. Johansson O., Liu P.-Y. "Electrosensitivity", "electrosupersensitivity" and "screen dermatitis": preliminary observations from on-going studies in the human skin. Proceedings of the COST 244 Biomedical Effects of Electromagnetic Fields - Workshop on Electromagnetic Hypersensitivity 1995, 52-57. EU/EC (DG XIII), Brussels/Graz. D. Simunic (Ed.).
52. Kabuto M., et al. Childhood leukemia and magnetic fields in Japan: a case-control study of childhood leukemia and residential power-frequency magnetic fields in Japan. Int J Cancer 2006, 119(3):643-650.
53. Kanaan R.A., Lepine J.P., Wessely S.C. The association or otherwise of the functional somatic syndromes. Psychosom Med 2007, 69(9):855-859.
54. Klimková-Deutschová E. Neurologic findings in persons exposed to microwaves. Biologic Effects and Health Hazards of Microwave Radiation: Proceedings of an International Symposium, Warsaw, 15-18 Oct 1973, 268-272. P. Czerski (Ed.).
55. Landgrebe M., et al. Cognitive and neurobiological alterations in electromagnetic hypersensitive patients: results of a case-control study. Psychol Med 2008, 38(12):1781-1791.
56. Landgrebe M., et al. Association of tinnitus and electromagnetic hypersensitivity: hints for a shared pathophysiology?. PLoS One 2009, 4(3):e5026.
57. Leitgeb N., Schrottner J. Electrosensibility and electromagnetic hypersensitivity. Bioelectromagnetics 2003, 24(6):387-394.
58. Less EMF Inc., The EMF Safety Superstore: EMF Shielding Device. Accessed on Oct 18th 2011 at []. 2011. http://lessemf.com/emf-shie.html.
59. Levallois P. Hypersensitivity of human subjects to environmental electric and magnetic field exposure: a review of the literature. Environ Health Perspect 2002, 110(Suppl 4):613-618.
60. Levallois P., et al. Study of self-reported hypersensitivity to electromagnetic fields in California. Environ Health Perspect 2002, 110(Suppl 4):619-623.
61. Li D.K., Chen H., Odouli R. Maternal exposure to magnetic fields during pregnancy in relation to the risk of asthma in offspring. Arch Pediatr Adolesc Med 2011, 165(10):945-950.
62. Lin H., et al. Electromagnetic field exposure induces rapid, transitory heat shock factor activation in human cells. J Cell Biochem 1997, 66(4):482-488.
63. Lin H., et al. Myc-mediated transactivation of HSP70 expression following exposure to magnetic fields. J Cell Biochem 1998, 69(2):181-188.
64. Marino A.A., et al. In vivo bioelectrochemical changes associated with exposure to extremely low frequency electric fields. Physiol Chem Phys 1977, 9(4-5):433-441.
65. Marshall B. Helicobacter pioneers: firsthand accounts from the scientists who discovered helicobacters 2002, Blackwell, Victoria, Australia.
66. Mashevich M., et al. Exposure of human peripheral blood lymphocytes to electromagnetic fields associated with cellular phones leads to chromosomal instability. Bioelectromagnetics 2003, 24(2):82-90.
67. McCarty DE, et al. Electromagnetic hypersensitivity: evidence for a novel neurological syndrome. Int J Neurosci. 2011 Sep 5. [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/21793784.
68. Michaels D. Doubt is their product: how industry's assault on science threatens you health 2008, Oxford University Press, New York.
69. Miller C.S. Toxicant-induced loss of tolerance - an emerging theory of disease?. Environ Health Perspect 1997, 105(Suppl 2):445-453.
70. Miller C.S. The compelling anomaly of chemical intolerance. Ann N Y Acad Sci 2001, 933:1-23.
71. Miller C.S., Ashford N.A. Multiple chemical intolerance and indoor air quality. Chapter 27 in 'Indoor air quality handbook' 2000, MacGraw-Hill, New York, 2000. J.D. Spengler, J.M. Samet, J.F. McCarthy (Eds.).
72. Mild K., Repacholi M., van Deventer E.e. Electromagnetic hypersensitivity. Proceedings International Workshop on EMF Hypersensitivity Prague, Czech Republic October 25-27 2004, 196.
73. Mortazavi S.M., Ahmadi J., Shariati M. Prevalence of subjective poor health symptoms associated with exposure to electromagnetic fields among university students. Bioelectromagnetics 2007, 28(4):326-330.
74. Moynihan R. Who pays for the pizza? Redefining the relationships between doctors and drug companies. 1: entanglement. BMJ 2003, 326(7400):1189-1192.
75. Nam K.C., et al. Hypersensitivity to RF fields emitted from CDMA cellular phones: a provocation study. Bioelectromagnetics 2009, 30(8):641-650.
76. National Post Editorials Spreading wireless panic 2011, A13. Saturday July 30, 2011, National Post.
77. Pall M.L. Explaining 'unexplained illness': disease paradigm for chronic fatigue syndrome, multiple chemical sensitivity, fibromyalgia; post-traumatic stress disorder, gulf war syndrome and others 2007, Harrington Park Press, New York.
78. Parsons, S., Living with electrohypersensitivity: a survival guide.[Acccessed on August 3rd, 2011 at ]. 2011. http://www.weepinitiative.org/livingwithEHS.html.
79. Ramirez C.C., Federman D.G., Kirsner R.S. Skin cancer as an occupational disease: the effect of ultraviolet and other forms of radiation. Int J Dermatol 2005, 44(2):95-100.
80. Rea W.J., et al. Electromagnetic field sensitivity. J Bioelectricity 1991, 10:241-256.
81. Rubin G.J., Das Munshi J., Wessely S. A systematic review of treatments for electromagnetic hypersensitivity. Psychother Psychosom 2006, 75(1):12-18.
82. Rubin G.J., Nieto-Hernandez R., Wessely S. Idiopathic environmental intolerance attributed to electromagnetic fields (formerly 'electromagnetic hypersensitivity'): an updated systematic review of provocation studies. Bioelectromagnetics 2010, 31(1):1-11.
83. Rubin G.J., Hillert L., Nieto-Hernandez R., van Rongen E., Oftedal G. Do people with idiopathic environmental intolerance attributed to electromagnetic fields display physiological effects when exposed to electromagnetic fields? A systematic review of provocation studies. Bioelectromagnetics 2011, 32(8):593-609.
84. Sadchikova M. State of the nervous system under the influence of UHF. The Biological Action of Ultrahigh Frequencies 1960, 25-29. Academy of Medical Sciences, Moscow. A.A. Letavet, Z.V. Gordon (Eds.).
85. Sage, C., The bioinitiative report. Accessed Aug 2/2011 at []. 2007. http://www.bioinitiative.org/report/index.htm.
86. Salford L.G., et al. The mammalian brain in the electromagnetic fields designed by man with special reference to blood-brain barrier function, neuronal damage and possible physical mechanisms. Progress of Theoretical Physics 2008, 283-309. Supplement No. 173.
87. Sears M. The medical perspective on environmental sensitivities 2007, Government of Canada: Canadian Human Rights Commission, Accessed Oct 22,2011 at. http://www.chrc-ccdp.gc.ca/legislation_policies/policy_environ_politique-eng.aspx.
88. Sears M. The medical perspective on environmental sensitivities 2007, available at, Government of Canada: Canadian Human Rights Commission, accessed Oct 11/2009. http://www.chrc-ccdp.ca/research_program_recherche/esensitivities_hypersensibilitee/toc_tdm-en.asp.
89. Stankiewicz W., et al. Immunotropic effects of low-level microwave exposures in vitro. National Institute for the Study and Control of Cancer and Environmental Disease 2010, 149-156. Mattioli, Bologna, 2010. L. Giuliani, M. Soffritti (Eds.).
90. Swedish Chemicals Agency, The Substitution Principle. Stockholm, Sweden. Accessed Oct 22,2011 at [.]. 2007. http://www.kemi.se/upload/Trycksaker/Pdf/Rapporter/Report8_07_The_Substitution_Principle.pdf.
91. The Swedish Association for the Electrosensitive, Electrically Hypersensitive Individuals Join Hands Across the World. Accessed Oct 22/2011 at []. 1994. http://www.feb.se/FEBLetters/world.html.
92. Torrens P. Wi-Fi geographies. Annals of the Association of American Geographers 2008, 98(1):59-84.
93. Tracey K.J. Physiology and immunology of the cholinergic antiinflammatory pathway. J Clin Invest 2007, 117(2):289-296.
94. Tsurita G., et al. Effects of exposure to repetitive pulsed magnetic stimulation on cell proliferation and expression of heat shock protein 70 in normal and malignant cells. Biochem Biophys Res Commun 1999, 261(3):689-694.
95. Volkow N.D., et al. Effects of cell phone radiofrequency signal exposure on brain glucose metabolism. JAMA 2011, 305(8):808-813.
96. Wormhoudt L.W., Commandeur J.N., Vermeulen N.P. Genetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione-S-transferase, and epoxide hydrolase enzymes: relevance to xenobiotic metabolism and toxicity. Crit Rev Toxicol 1999, 29(1):59-124.
97. World Health Organization, Electromagnetic Fields and Public Health: Electromagnetic Hypersensitivity. [accessed on July 31. 2011 at ]. 2005. http://www.who.int/mediacentre/factsheets/fs296/en/index.html.
98. World Health Organization, Electromagnetic Fields. [accessed on July 7th 2011 at ]. 2011. http://www.who.int/peh-emf/en/.
99. Zaret M. Microwave cataracts. Medical Trial Technique Quarterly 1973, 19(3):246-252.