Killer-cell immunoglobulin-like receptors and malaria caused by Plasmodium falciparum in The Gambia

Tissue Antigens

Volumn 79, Issue 2, 2012, Pages 104-113

  Yindom, L M ^a,b   Forbes, R ^a   Aka, P ^a   Janha, O ^a   Jeffries, D ^a   Jallow, M ^a   Conway, D J ^a   Walther, M ^a  

^a MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Gambia; Human leukocyte antigen; Killer cell immunoglobulin like receptor; Malaria; Natural killer cells; Plasmodium falciparum

Indexed keywords

GENOMIC DNA; HLA ANTIGEN CLASS 1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL3; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL4; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL5; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DP1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL3; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DS1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DS2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DS3; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DS4; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DS5; UNCLASSIFIED DRUG;

ARTICLE; CHILD; CHILDHOOD MORTALITY; CONTROLLED STUDY; DISEASE SEVERITY; ETHNIC DIFFERENCE; FEMALE; GAMBIA; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; INFECTION SENSITIVITY; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; PARASITEMIA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTECTION; RECEPTOR GENE; UMBILICAL CORD BLOOD;

CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; FETAL BLOOD; GAMBIA; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IMMUNITY, INNATE; INFANT; INFANT, NEWBORN; INTERFERON-GAMMA; KILLER CELLS, NATURAL; MALARIA, FALCIPARUM; MALE; PLASMODIUM FALCIPARUM; PROTEIN ISOFORMS; RECEPTORS, KIR; SEVERITY OF ILLNESS INDEX; SURVIVAL RATE;

PLASMODIUM FALCIPARUM;

EID: 84855513987     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2011.01818.x     Document Type: Article

References (56)

1. Langhorne J, Ndungu FM, Sponaas AM, Marsh K. Immunity to malaria: more questions than answers. Nat Immunol 2008: 9: 725-32.
2. Kwiatkowski DP. How malaria has affected the human genome and what human genetics can teach us about malaria. Am J Hum Genet 2005: 77: 171-92.
3. Mackinnon MJ, Mwangi TW, Snow RW, Marsh K, Williams TN. Heritability of malaria in Africa. PLoS Med 2005: 2: e340.
4. Smyth MJ, Cretney E, Kelly JM et al. Activation of NK cell cytotoxicity. Mol Immunol 2005: 42: 501-10.
5. Lodoen MB, Lanier LL. Natural killer cells as an initial defense against pathogens. Curr Opin Immunol 2006: 18: 391-8.
6. Ljunggren HG, Karre K. In search of the 'missing self': MHC molecules and NK cell recognition. Immunol Today 1990: 11: 237-44.
7. Newman KC, Riley EM. Whatever turns you on: accessory- cell-dependent activation of NK cells by pathogens. Nat Rev Immunol 2007: 7: 279-91.
8. Korbel DS, Finney OC, Riley EM. Natural killer cells and innate immunity to protozoan pathogens. Int J Parasitol 2004: 34: 1517-28.
9. Mohan K, Moulin P, Stevenson MM. Natural killer cell cytokine production, not cytotoxicity, contributes to resistance against blood-stage Plasmodium chabaudi AS infection. J Immunol 1997: 159: 4990-8.
10. Artavanis-Tsakonas K, Riley EM. Innate immune response to malaria: rapid induction of IFN-gamma from human NK cells by live Plasmodium falciparum-infected erythrocytes. J Immunol 2002: 169: 2956-63.
11. Newman KC, Korbel DS, Hafalla JC, Riley EM. Cross-talk with myeloid accessory cells regulates human natural killer cell interferon-gamma responses to malaria. PLoS Pathog 2006: 2: e118.
12. Korbel DS, Newman KC, Almeida CR, Davis DM, Riley EM. Heterogeneous human NK cell responses to Plasmodium falciparum-infected erythrocytes. J Immunol 2005: 175: 7466-73.
13. Artavanis-Tsakonas K, Eleme K, McQueen KL et al. Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes. J Immunol 2003: 171: 5396-405.
14. Korbel DS, Norman PJ, Newman KC et al. Killer Ig-like receptor (KIR) genotype predicts the capacity of human KIR-positive CD56dim NK cells to respond to pathogen- associated signals. J Immunol 2009: 182: 6426-34.
15. Cooper MA, Fehniger TA, Caligiuri MA. The biology of human natural killer-cell subsets. Trends Immunol 2001: 22: 633-40.
16. Cooley S, Xiao F, Pitt M et al. A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature. Blood 2007: 110: 578-86.
17. Jacobs R, Hintzen G, Kemper A et al. CD56bright cells differ in their KIR repertoire and cytotoxic features from CD56dim NK cells. Eur J Immunol 2001: 31: 3121-7.
18. Mingari MC, Schiavetti F, Ponte M et al. Human CD8+ T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations. Proc Natl Acad Sci U S A 1996: 93: 12433-8.
19. Parham P. The genetic and evolutionary balances in human NK cell receptor diversity. Semin Immunol 2008: 20: 311-6.
20. Long EO. Regulation of immune responses through inhibitory receptors. Annu Rev Immunol 1999: 17: 875-904.
21. Older Aguilar AM, Guethlein LA, Adams EJ, Abi-Rached L, Moesta AK, Parham P. Coevolution of killer cell Ig-like receptors with HLA-C to become the major variable regulators of human NK cells. J Immunol 2010: 185: 4238-51.
22. Guinan KJ, Cunningham RT, Meenagh A et al. Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes. Genes Immun 2010: 11: 467-78.
23. Rauch A, Laird R, McKinnon E et al. Influence of inhibitory killer immunoglobulin-like receptors and their HLA-C ligands on resolving hepatitis C virus infection. Tissue Antigens 2007: 69 (Suppl 1): 237-40.
24. Rajagopalan S, Long EO. Understanding how combinations of HLA and KIR genes influence disease. J Exp Med 2005: 201: 1025-9.
25. Yamazaki A, Yasunami M, Ofori M et al. Human leukocyte antigen class I polymorphisms influence the mild clinical manifestation of Plasmodium falciparum infection in Ghanaian children. Hum Immunol 2011.
26. Carrington M, Wang S, Martin MP et al. Hierarchy of resistance to cervical neoplasia mediated by combinations of killer immunoglobulin-like receptor and human leukocyte antigen loci. J Exp Med 2005: 201: 1069-75.
27. Gaudieri S, DeSantis D, McKinnon E et al. Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progression. Genes Immun 2005: 6: 683-90.
28. Hiby SE, Walker JJ, O'Shaughnessy KM et al. Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success. J Exp Med 2004: 200: 957-65.
29. Martin MP, Gao X, Lee JH et al. Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nat Genet 2002: 31: 429-34.
30. Martin MP, Nelson G, Lee JH et al. Cutting edge: susceptibility to psoriatic arthritis: influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles. J Immunol 2002: 169: 2818-22.
31. Middleton D, Diler AS, Meenagh A, Sleator C, Gourraud PA. Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia. Tissue Antigens 2009: 73: 553-60.
32. van der Slik AR, Koeleman BP, Verduijn W, Bruining GJ, Roep BO, Giphart MJ. KIR in type 1 diabetes: disparate distribution of activating and inhibitory natural killer cell receptors in patients versus HLA-matched control subjects. Diabetes 2003: 52: 2639-42.
33. Yindom LM, Leligdowicz A, Martin MP et al. Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa. J Virol 2010: 84: 8202-8.
34. Hill AV, Allsopp CE, Kwiatkowski D et al. Common west African HLA antigens are associated with protection from severe malaria. Nature 1991: 352: 595-600.
35. Lyke KE, Fernandez-Vina MA, Cao K et al. Association of HLA alleles with Plasmodium falciparum severity in Malian children. Tissue Antigens 2011: 77: 562-71.
36. Taniguchi M, Kawabata M. KIR3DL1/S1 genotypes and KIR2DS4 allelic variants in the AB KIR genotypes are associated with Plasmodium-positive individuals in malaria infection. Immunogenetics 2009: 61: 717-30.
37. Hill AV, Elvin J, Willis AC et al. Molecular analysis of the association of HLA-B53 and resistance to severe malaria. Nature 1992: 360: 434-9.
38. World Health Organization CDC. Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster. Trans R Soc Trop Med Hyg 2000: 94 (Suppl 1): S1-90.
39. Walther M, Jeffries D, Finney OC et al. Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria. PLoS Pathog 2009: 5: e1000364.
40. Gomez-Escobar N, Amambua-Ngwa A, Walther M, Okebe J, Ebonyi A, Conway DJ. Erythrocyte invasion and merozoite ligand gene expression in severe and mild Plasmodium falciparum malaria. J Infect Dis 2010: 201: 444-52.
41. Marsh K, Forster D, Waruiru C et al. Indicators of life-threatening malaria in African children. N Engl J Med 1995: 332: 1399-404.
42. Jallow M, Teo YY, Small KS et al. Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet 2009: 41: 657-65.
43. Martin MP, Carrington M. KIR locus polymorphisms: genotyping and disease association analysis. Methods Mol Biol 2008: 415: 49-64.
44. Cooley S, Weisdorf DJ, Guethlein LA et al. Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia. Blood 2010: 116: 2411-9.
45. Pyo CW, Guethlein LA, Vu Q et al. Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus. PLoS ONE 2010: 5: e15115.
46. Gonzalez-Galarza FF, Christmas S, Middleton D, Jones AR. Allele frequency net: a database and online repository for immune gene frequencies in worldwide populations. Nucleic Acids Res 2011: 39: D913-9.
47. Single RM, Martin MP, Meyer D, Gao X, Carrington M. Methods for assessing gene content diversity of KIR with examples from a global set of populations. Immunogenetics 2008: 60: 711-25.
48. Single RM, Martin MP, Gao X et al. Global diversity and evidence for coevolution of KIR and HLA. Nat Genet 2007: 39: 1114-9.
49. Walther M, Woodruff J, Edele F et al. Innate immune responses to human malaria: heterogeneous cytokine responses to blood-stage Plasmodium falciparum correlate with parasitol- ogical and clinical outcomes. J Immunol 2006: 177: 5736-45.
50. Denis L, Sivula J, Gourraud PA et al. Genetic diversity of KIR natural killer cell markers in populations from France, Guadeloupe, Finland, Senegal and Reunion. Tissue Antigens 2005: 66: 267-76.
51. Estefania E, Gomez-Lozano N, Portero F et al. Influence of KIR gene diversity on the course of HSV-1 infection: resistance to the disease is associated with the absence of KIR2DL2 and KIR2DS2. Tissue Antigens 2007: 70: 34-41.
52. Kim S, Poursine-Laurent J, Truscott SM et al. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 2005: 436: 709-13.
53. Raulet DH, Vance RE. Self-tolerance of natural killer cells. Nat Rev Immunol 2006: 6: 520-31.
54. Anfossi N, Andre P, Guia S et al. Human NK cell education by inhibitory receptors for MHC class I. Immunity 2006: 25: 331-42.
55. Norman PJ, Abi-Rached L, Gendzekhadze K et al. Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans. Nat Genet 2007: 39: 1092-9.
56. Artavanis-Tsakonas K, Tongren JE, Riley EM. The war between the malaria parasite and the immune system: immunity, immunoregulation and immunopathology. Clin Exp Immunol 2003: 133: 145-52.