Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa

Journal of Virology

Volumn 84, Issue 16, 2010, Pages 8202-8208

  Yindom, Louis Marie ^a   Leligdowicz, Aleksandra ^a,b   Martin, Maureen P ^c   Gao, Xiaojiang ^c   Qi, Ying ^c   Zaman, Syed M A ^a,d   Van Der Loeff, Maarten Schim ^a,e   Van Tienen, Carla ^a   Jaye, Assan ^a   Aveika, Akum ^a   Worwui, Archibald ^a   Diatta, Mathurin ^a   Vincent, Tim ^a   Whittle, Hilton C ^a   Rowland Jones, Sarah L ^a,b   Walton, Robert ^a,f   Carrington, Mary ^c,g  

^a Medical Research   (Gambia)

^b MRC Human Immunology   (United Kingdom)

^c SAIC FREDERICK INC   (United States)

^d PUBLIC HEALTH ENGLAND   (United Kingdom)

^e MUNICIPAL HEALTH SERVICE   (Netherlands)

^f QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN CLASS 1; HLA B ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR;

ADULT; AFRICA; AGED; ARTICLE; CLADISTICS; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 2 INFECTION; INFECTION RESISTANCE; INFECTION SENSITIVITY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; VIRUS LOAD;

ADULT; AFRICA, WESTERN; AGED; DISEASE PROGRESSION; ETHNIC GROUPS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV INFECTIONS; HIV-2; HLA-B ANTIGENS; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTORS, KIR;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2;

EID: 77954990256     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00116-10     Document Type: Article

References (45)

1. Aaby, P., K. Ariyoshi, M. Buckner, H. Jensen, N. Berry, A. Wilkins, D. Richard, O. Larsen, F. Dias, M. Melbye, and H. Whittle. 1996. Age of wife as a major determinant of male-to-female transmission of HIV-2 infection: a community study from rural West Africa. AIDS 10:1585-1590.
2. Barin, F., S. M'Boup, F. Denis, P. Kanki, J. S. Allan, T. H. Lee, and M. Essex. 1985. Serological evidence for virus related to simian T-lymphotropic retrovirus III in residents of west Africa. Lancet ii:1387-1389.
3. Berry, N., S. Jaffar, M. Schim van der Loeff, K. Ariyoshi, E. Harding, P. T. N'Gom, F. Dias, A. Wilkins, D. Ricard, P. Aaby, R. Tedder, and H. Whittle. 2002. Low level viremia and high CD4% predict normal survival in a cohort of HIV type-2-infected villagers. AIDS Res. Hum. Retrovir. 18:1167-1173.
4. Bjorling, E., G. Scarlatti, A. von Gegerfelt, J. Albert, G. Biberfeld, F. Chiodi, E. Norrby, and E. M. Fenyo. 1993. Autologous neutralizing antibodies prevail in HIV-2 but not in HIV-1 infection. Virology 193:528-530.
5. Boily, M. C., R. F. Baggaley, L. Wang, B. Masse, R. G. White, R. J. Hayes, and M. Alary. 2009. Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies. Lancet Infect. Dis. 9:118-129.
6. Buckner, M. 2000. Manjako sex and gender. Ph.D. thesis. University of Paris X, Nanterre, France.
7. Cao, K., A. M. Moormann, K. E. Lyke, C. Masaberg, O. P. Sumba, O. K. Doumbo, D. Koech, A. Lancaster, M. Nelson, D. Meyer, R. Single, R. J. Hartzman, C. V. Plowe, J. Kazura, D. L. Mann, M. B. Sztein, G. Thomson, and M. A. Fernandez-Vina. 2004. Differentiation between African populations is evidenced by the diversity of alleles and haplotypes of HLA class I loci. Tissue Antigens 63:293-325.
8. Carr, W. H., M. J. Pando, and P. Parham. 2005. KIR3DL1 polymorphisms that affect NK cell inhibition by HLA-Bw4 ligand. J. Immunol. 175:5222-5229.
9. Carrington, M., M. P. Martin, and J. van Bergen. 2008. KIR-HLA intercourse in HIV disease. Trends Microbiol. 16:620-627.
10. Carrington, M., and S. J. O'Brien. 2003. The influence of HLA genotype on AIDS. Annu. Rev. Med. 54:535-551.
11. Clavel, F., D. Guetard, F. Brun-Vezinet, S. Chamaret, M. A. Rey, M. O. Santos-Ferreira, A. G. Laurent, C. Dauguet, C. Katlama, C. Rouzioux, et al. 1986. Isolation of a new human retrovirus from West African patients with AIDS. Science 233:343-346.
12. De Cock, K. M., K. Odehouri, R. L. Colebunders, G. Adjorlolo, M. F. Lafontaine, A. Porter, E. Gnaore, L. Diaby, J. Moreau, W. L. Heyward, et al. 1990. A comparison of HIV-1 and HIV-2 infections in hospitalized patients in Abidjan, Cote d'Ivoire. AIDS 4:443-448.
13. Denis, L., J. Sivula, P. A. Gourraud, N. Kerdudou, R. Chout, C. Ricard, J. P. Moisan, K. Gagne, J. Partanen, and J. D. Bignon. 2005. Genetic diversity of KIR natural killer cell markers in populations from France, Guadeloupe, Finland, Senegal, and Reunion. Tissue Antigens 66:267-276.
14. Diouf, K., A. D. Sarr, G. Eisen, S. Popper, S. Mboup, and P. Kanki. 2002. Associations between MHC class I and susceptibility to HIV-2 disease progression. J. Hum. Virol. 5:1-7.
15. + T-cell help distinguishes HIV-2 from HIV-1 infection. J. Immunol. 176:6973-6981.
16. Excoffier, L. G. L., and S. Schneider. 2005. Arlequin ver. 3.0: an integrated software package for population genetics data analysis. Evolutionary Bioinformatics Online 1:47-50.
17. Fellay, J., K. V. Shianna, D. Ge, S. Colombo, B. Ledergerber, M. Weale, K. Zhang, C. Gumbs, A. Castagna, A. Cossarizza, A. Cozzi-Lepri, A. De Luca, P. Easterbrook, P. Francioli, S. Mallal, J. Martinez-Picado, J. M. Miro, N. Obel, J. P. Smith, J. Wyniger, P. Descombes, S. E. Antonarakis, N. L. Letvin, A. J. McMichael, B. F. Haynes, A. Telenti, and D. B. Goldstein. 2007. A whole-genome association study of major determinants for host control of HIV-1. Science 317:944-947.
18. Frahm, N., P. Kiepiela, S. Adams, C. H. Linde, H. S. Hewitt, K. Sango, M. E. Feeney, M. M. Addo, M. Lichterfeld, M. P. Lahaie, E. Pae, A. G. Wurcel, T. Roach, M. A. St John, M. Altfeld, F. M. Marincola, C. Moore, S. Mallal, M. Carrington, D. Heckerman, T. M. Allen, J. I. Mullins, B. T. Korber, P. J. Goulder, B. D. Walker, and C. Brander. 2006. Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes. Nat. Immunol. 7:173-178.
19. Gao, X., G. W. Nelson, P. Karacki, M. P. Martin, J. Phair, R. Kaslow, J. J. Goedert, S. Buchbinder, K. Hoots, D. Vlahov, S. J. O'Brien, and M. Carrington. 2001. Effect of a single amino acid change in MHC class I molecules on the rate of progression to AIDS. N. Engl. J. Med. 344:1668-1675.
20. Guyader, M., M. Emerman, P. Sonigo, F. Clavel, L. Montagnier, and M. Alizon. 1987. Genome organization and transactivation of the human immunodeficiency virus type 2. Nature 326:662-669.
21. Holmgren, B., P. Aaby, H. Jensen, O. Larsen, Z. da Silva, and I. M. Lisse. 1999. Increased prevalence of retrovirus infections among older women in Africa. Scand. J. Infect. Dis. 31:459-466.
22. Holmgren, B., Z. da Silva, O. Larsen, P. Vastrup, S. Andersson, and P. Aaby. 2003. Dual infections with HIV-1, HIV-2 and HTLV-1 are more common in older women than in men in Guinea-Bissau. AIDS 17:241-253.
23. Jonsson, A. H., and W. M. Yokoyama. 2009. Natural killer cell tolerance licensing and other mechanisms. Adv. Immunol. 101:27-79.
24. Kaslow, R. A., M. Carrington, R. Apple, L. Park, A. Munoz, A. J. Saah, J. J. Goedert, C. Winkler, S. J. O'Brien, C. Rinaldo, R. Detels, W. Blattner, J. Phair, H. Erlich, and D. L. Mann. 1996. Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection. Nat. Med. 2:405-411.
25. Kilmarx, P. H. 2009. Global epidemiology of HIV. Curr. Opin. HIV AIDS 4:240-246.
26. Lanier, L. L. 2008. Up on the tightrope: natural killer cell activation and inhibition. Nat. Immunol. 9:495-502.
27. Larsen, O., Z. da Silva, A. Sandstrom, P. K. Andersen, S. Andersson, A. G. Poulsen, M. Melbye, F. Dias, A. Naucler, and P. Aaby. 1998. Declining HIV-2 prevalence and incidence among men in a community study from Guinea-Bissau. AIDS 12:1707-1714.
28. Leligdowicz, A., L. M. Yindom, C. Onyango, R. Sarge-Njie, A. Alabi, M. Cotten, T. Vincent, C. da Costa, P. Aaby, A. Jaye, T. Dong, A. McMichael, H. Whittle, and S. Rowland-Jones. 2007. Robust Gag-specific T-cell responses characterize viremia control in HIV-2 infection. J. Clin. Invest. 117:3067-3074.
29. MacDonald, K. S., J. Embree, S. Njenga, N. J. Nagelkerke, I. Ngatia, Z. Mohammed, B. H. Barber, J. Ndinya-Achola, J. Bwayo, and F. A. Plummer. 1998. Mother-child class I HLA concordance increases perinatal human immunodeficiency virus type 1 transmission. J. Infect. Dis. 177:551-556.
30. Mackelprang, R. D., G. John-Stewart, M. Carrington, B. Richardson, S. Rowland-Jones, X. Gao, D. Mbori-Ngacha, J. Mabuka, B. Lohman-Payne, and C. Farquhar. 2008. Maternal HLA homozygosity and mother-child HLA concordance increase the risk of vertical transmission of HIV-1. J. Infect. Dis. 197:1156-1161.
31. Martin, M. P., and M. Carrington. 2008. KIR locus polymorphisms: geno-typing and disease association analysis. Methods Mol. Biol. 415:49-64.
32. Martin, M. P., X. Gao, J. H. Lee, G. W. Nelson, R. Detels, J. J. Goedert, S. Buchbinder, K. Hoots, D. Vlahov, J. Trowsdale, M. Wilson, S. J. O'Brien, and M. Carrington. 2002. Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nat. Genet. 31:429-434.
33. Middleton, D., L. Menchaca, H. Rood, and R. Komerofsky. 2003. New allele frequency database: http://www.allelefrequencies.net. Tissue Antigens 61: 403-407.
34. Onyango, C., A. Leligdowicz, A. Yokoyama, H. Sato, H. Song, E. E. Nakayama, T. Shiodad, T. de Silva, J. Townend, A. Jaye, H. Whittle, S. Rowland- Jones, and M. Cotten. 2009. HIV-2 capsids distinguish high and low virus load patients in a West African community cohort. Vaccine [Epub ahead of print.] doi:10.1016/j.vaccine.2009.08.060.
35. Ricard, D., A. Wilkins, P. T. N'Gum, R. Hayes, G. Morgan, A. P. Da Silva, and H. Whittle. 1994. The effects of HIV-2 infection in a rural area of Guinea-Bissau. AIDS 8:977-982.
36. Rowland-Jones, S., J. Sutton, K. Ariyoshi, T. Dong, F. Gotch, S. McAdam, D. Whitby, S. Sabally, A. Gallimore, T. Corrah, et al. 1995. HIV-specific cytotoxic T cells in HIV-exposed but uninfected Gambian women. Nat. Med. 1:59-64.
37. Rowland-Jones, S. L., and H. C. Whittle. 2007. Out of Africa: what can we learn from HIV-2 about protective immunity to HIV-1? Nat. Immunol. 8:329-331.
38. Sanchez-Mazas, A., Q. G. Steiner, C. Grundschober, and J. M. Tiercy. 2000. The molecular determination of HLA-Cw alleles in the Mandenka (West Africa) reveals a close genetic relationship between Africans and Europeans. Tissue Antigens 56:303-312.
39. Schim van der Loeff, M. F., and P. Aaby. 1999. Towards a better understanding of the epidemiology of HIV-2. Aids 13(Suppl. A):S69-S84.
40. Schmidt, W. P., M. S. Van Der Loeff, P. Aaby, H. Whittle, R. Bakker, M. Buckner, F. Dias, and R. G. White. 2008. Behavioor change and competitive exclusion can explain the diverging HIV-1 and HIV-2 prevalence trends in Guinea-Bissau. Epidemiol. Infect. 136:551-561.
41. Serwanga, J., L. A. Shafer, E. Pimego, B. Auma, C. Watera, S. Rowland, D. Yirrell, P. Pala, H. Grosskurth, J. Whitworth, F. Gotch, and P. Kaleebu. 2009. Host HLA B*allele-associated multi-clade Gag T-cell recognition correlates with slow HIV-1 disease progression in antiretroviral therapy-naive Ugandans. PLoS One 4:e4188.
42. Single, R. M., M. P. Martin, X. Gao, D. Meyer, M. Yeager, J. R. Kidd, K. K. Kidd, and M. Carrington. 2007. Global diversity and evidence for coevolution of KIR and HLA. Nat. Genet. 39:1114-1119.
43. Stewart, C. A., F. Laugier-Anfossi, F. Vely, X. Saulquin, J. Riedmuller, A. Tisserant, L. Gauthier, F. Romagne, G. Ferracci, F. A. Arosa, A. Moretta, P. D. Sun, S. Ugolini, and E. Vivier. 2005. Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors. Proc. Natl. Acad. Sci. U. S. A. 102:13224-13229.
44. Trachtenberg, E., B. Korber, C. Sollars, T. B. Kepler, P. T. Hraber, E. Hayes, R. Funkhouser, M. Fugate, J. Theiler, Y. S. Hsu, K. Kunstman, S. Wu, J. Phair, H. Erlich, and S. Wolinsky. 2003. Advantage of rare HLA supertype in HIV disease progression. Nat. Med. 9:928-935.
45. Wilkins, A., D. Ricard, J. Todd, H. Whittle, F. Dias, and A. Paulo Da Silva. 1993. The epidemiology of HIV infection in a rural area of Guinea-Bissau. AIDS 7:1119-1122.