Neoplastic MiR-17~92 deregulation at a DNA fragility motif (SIDD)

Genes Chromosomes and Cancer

Volumn 51, Issue 3, 2012, Pages 219-228

  Schneider, Björn ^a,c   Nagel, Stefan ^a   Ehrentraut, Stefan ^a   Kaufmann, Maren ^a   Meyer, Corinna ^a   Geffers, Robert ^b   Drexler, Hans G ^a   MacLeod, Roderick A F ^a  

^a LEIBNIZ INSTITUTE DSMZ GERMAN COLLECTION OF MICROORGANISMS AND CELL CULTURES   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AZACITIDINE; COMPLEMENTARY DNA; DNA; MESSENGER RNA; MICRORNA;

ARTICLE; B CELL LYMPHOMA; CHROMOSOME 13Q; CYTOGENETICS; DNA FRAGILITY MOTIF; DNA STRAND BREAKAGE; GENE EXPRESSION; GENE REARRANGEMENT; HUMAN; HUMAN CELL; LARGE CELL LYMPHOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SPECIFIC DNA INSTABILITY MOTIF; STRESS INDUCED DNA DUPLEX DESTABILIZATION;

ACETYLATION; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME BANDING; CHROMOSOME BREAKPOINTS; CHROMOSOME FRAGILE SITES; DNA; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONES; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; LYMPHOMA, LARGE B-CELL, DIFFUSE; MICRORNAS; NEOPLASM PROTEINS; ONCOGENE PROTEINS, FUSION; REGULATORY SEQUENCES, NUCLEIC ACID; TRANSLOCATION, GENETIC;

EID: 84855502487     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20946     Document Type: Article

References (38)

1. Akasaka T, Lossos IS, Levy R. 2003. BCL6 gene translocation in follicular lymphoma: A harbinger of eventual transformation to diffuse aggressive lymphoma. Blood 102: 1443-1448.
2. Benham CJ. 1996. Duplex destabilization in superhelical DNA is predicted to occur at specific transcriptional regulatory regions. J Mol Biol 255: 425-434.
3. Benham C, Kohwi-Shigematsu T, Bode J. 1997. Stress-induced duplex DNA destabilization in scaffold/matrix attachment regions. J Mol Biol 274: 181-196.
4. Bi C, Benham CJ. 2004. WebSIDD: Server for predicting stress-induced duplex destabilized (SIDD) sites in superhelical DNA. Bioinformatics 20: 1477-1479.
5. Bousquet M, Quelen C, Rosati R, Mansat-De Mas V, La Starza R, Bastard C, Lippert E, Talmant P, Lafage-Pochitaloff M, Leroux D, Gervais C, Viguié F, Lai JL, Terre C, Beverloo B, Sambani C, Hagemeijer A, Marynen P, Delsol G, Dastugue N, Mecucci C, Brousset P. 2008. Myeloid cell differentiation arrest by miR-125b-1 in myelodysplastic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation. J Exp Med 205: 2499-2506.
6. Butler MP, Iida S, Capello D, Rossi D, Rao PH, Nallasivam P, Louie DC, Chaganti S, Au T, Gascoyne RD, Gaidano G, Chaganti RS, Dalla-Favera R. 2002. Alternative translocation breakpoint cluster region 5′ to BCL-6 in B-cell non-Hodgkin's lymphoma. Cancer Res 62: 4089-4094.
7. Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, Yendamuri S, Shimizu M, Rattan S, Bullrich F, Negrini M, Croce CM. 2004. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 101: 2999-3004.
8. Chapiro E, Russell LJ, Struski S, Cavé H, Radford-Weiss I, Valle VD, Lachenaud J, Brousset P, Bernard OA, Harrison CJ, Nguyen-Khac F. 2010. A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia. Leukemia 24: 1362-1364.
9. Chen RW, Bemis LT, Amato CM, Myint H, Tran H, Birks DK, Eckhardt SG, Robinson WA. 2008. Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma. Blood 112: 822-829.
10. Dessen P, Huret JL. Chromosome. Atlas Genet Cytogenet Oncol Haematol. Available at: Accessed on October, 2011.
11. Drexler HG. 2001. The Leukemia-Lymphoma Cell Lines FactsBook. London: Academic Press.
12. Drexler HG. 2010. Guide to Leukemia-Lymphoma Cell Lines, 2nd ed. DSMZ: Braunschweig.
13. Elenitoba-Johnson KS, Jenson SD, Abbott RT, Palais RA, Bohling SD, Lin Z, Tripp S, Shami PJ, Wang LY, Coupland RW, Buckstein R, Perez-Ordonez B, Perkins SL, Dube ID, Lim MS. 2003. Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy. Proc Natl Acad Sci USA 100: 7259-7264.
14. Fabbri M, Calin GA. 2010. Epigenetics and miRNAs in human cancer. Adv Genet 70: 87-99.
15. Frohman MA, Dush MK, Martin GR. 1988. Rapid production of full-length cDNAs from rare transcripts: Amplification using a single gene-specific oligonucleotide primer. Proc Natl Acad Sci USA 85: 8998-9002.
16. Guo H, Ingolia NT, Weissman JS, Bartel DP. 2010. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466: 835-840.
17. He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, Goodson S, Powers S, Cordon-Cardo C, Lowe SW, Hannon GJ, Hammond SM. 2005. A microRNA polycistron as a potential human oncogene. Nature 435: 828-833.
18. Inomata M, Tagawa H, Guo YM, Kameoka Y, Takahashi N, Sawada K. 2009. MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. Blood 113: 396-402.
19. Knezevich S. 2007. BCL6 (B-Cell Lymphoma 6). Atlas Genet Cytogenet Oncol Hematol. Available at:.
20. Lau PW, MacRae IJ. 2009. The molecular machines that mediate microRNA maturation. J Cell Mol Med 13: 54-60.
21. Lenz G, Wright GW, Emre NC, Kohlhammer H, Dave SS, Davis RE, Carty S, Lam LT, Shaffer AL, Xiao W, Powell J, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Campo E, Jaffe ES, Delabie J, Smeland EB, Rimsza LM, Fisher RI, Weisenburger DD, Chan WC, Staudt LM. 2008. Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways. Proc Natl Acad Sci USA 105: 13520-13525.
22. MacLeod RAF, Kaufmann M, Drexler HG. 2007. Cytogenetic harvesting of commonly used tumour cell lines. Nat Protoc 2: 372-382.
23. Martens JH, Verlaan M, Kalkhoven E, Dorsman JC, Zantema A. 2002. Scaffold/matrix attachment region elements interact with a p300-scaffold attachment factor A complex and are bound by acetylated nucleosomes. Mol Cell Biol 22: 2598-2606.
24. Mitelman F, Johansson B, Mertens F, editors. 2011. Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer; Available at:.
25. Mishmar D, Rahat A, Scherer SW, Nyakatura G, Hinzmann B, Kohwi Y, Mandel-Gutfroind Y, Lee JR, Drescher B, Sas DE, Margalit H, Platzer M, Weiss A, Tsui LC, Rosenthal A, Kerem B. 1998. Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site. Proc Natl Acad Sci USA 95: 8141-8146.
26. O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. 2005. c-MYC-regulated micro RNAs modulate E2F1 expression. Nature 435: 839-843.
27. Ota A, Tagawa H, Karnan S, Tsuzuki S, Karpas A, Kira S, Yoshida Y, Seto M. 2004. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. Cancer Res 64: 3087-3095.
28. Pasqualucci L, Migliazza A, Basso K, Houldsworth J, Chaganti RS, Dalla-Favera R. 2003. Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma. Blood 101: 2914-2923.
29. Phan RT, Dalla-Favera R. 2004. The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells. Nature 432: 635-639.
30. Schneider B, Nagel S, Kaufmann M, Winkelmann S, Bode J, Drexler HG, Macleod RAF. 2008. t(3;7)(q27;q32) fuses BCL6 to a non-coding region at FRA7H near miR-29. Leukemia 22: 1262-1266.
31. Schneider B, Drexler HG, MacLeod RAF. 2011. Molecular breakpoint analysis of chromosome translocations in cancer cell lines by Long Distance Inverse-PCR. Methods Mol Biol 731: 321-332.
32. Sylvestre Y, De Guire V, Querido E, Mukhopadhyay UK, Bourdeau V, Major F, Ferbeyre G, Chartrand P. 2006. An E2F/miR-20a autoregulatory feedback loop. J Biol Chem 282: 2135-2143.
33. Ventura A, Jacks T. 2009. MicroRNAs and cancer: short RNAs go a long way. Cell 136: 586-591.
34. Wang H, Noordewier M, Benham CJ. 2004. Stress-induced DNA duplex destabilization (SIDD) in the E. coli genome: SIDD sites are closely associated with promoters. Genome Res 14: 1575-1584.
35. Wiestner A, Tehrani M, Chiorazzi M, Wright G, Gibellini F, Nakayama K, Liu H, Rosenwald A, Muller-Hermelink HK, Ott G, Chan WC, Greiner TC, Weisenburger DD, Vose J, Armitage JO, Gascoyne RD, Connors JM, Campo E, Montserrat E, Bosch F, Smeland EB, Kvaloy S, Holte H, Delabie J, Fisher RI, Grogan TM, Miller TP, Wilson WH, Jaffe ES, Staudt LM. 2007. Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival. Blood. 109: 4599-4606.
36. Willis TG, Jadayel DM, Coignet LJ, Abdul-Rauf M, Treleaven JG, Catovsky D, Dyer MJ. 1997. Rapid molecular cloning of rearrangements of the IGHJ locus using long-distance inverse polymerase chain reaction. Blood 90: 2456-2464.
37. Xiao C, Srinivasan L, Calado DP, Patterson HC, Zhang B, Wang J, Henderson JM, Kutok JL, Rajewsky K. 2008. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol 9: 404-414.
38. Ye BH, Lista F, Lo Coco F, Knowles DM, Offit K, Chaganti RS, Dalla-Favera R. 1993. Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma. Science 262: 747-750.