Human vascular endothelial cells reduce sphingosylphosphorylcholine-induced smooth muscle cell contraction in co-culture system through integrin Β4 and Fyn

Acta Pharmacologica Sinica

Volumn 33, Issue 1, 2012, Pages 57-65

  Ge, Di ^a   Meng, Ning ^a   Su, Le ^a,b   Zhang, Yun ^b   Zhang, Shang Li ^a,b   Miao, Jun Ying ^a,b   Zhao, Jing ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

contraction; Fyn; human umbilical vein; integrin 4; sphingosylphosphorylcholine; vascular endothelial cells; vascular smooth muscle cells

Indexed keywords

BETA4 INTEGRIN; COLLAGEN; NITRIC OXIDE; PROTEIN KINASE FYN; RHO KINASE; SMALL INTERFERING RNA; SPHINGOSYLPHOSPHORYLCHOLINE;

ARTICLE; CELL CULTURE; CELL FUNCTION; COCULTURE; CONTROLLED STUDY; DATA ANALYSIS SOFTWARE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOASSAY; IMMUNOFLUORESCENCE TEST; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RECEPTOR DOWN REGULATION; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER; SUPERNATANT; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR SMOOTH MUSCLE; VASCULAR SMOOTH MUSCLE CELL; WESTERN BLOTTING;

ANIMALS; CELLS, CULTURED; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; HUMANS; INTEGRIN BETA4; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NITRIC OXIDE; PHOSPHORYLCHOLINE; PROTO-ONCOGENE PROTEINS C-FYN; RHO-ASSOCIATED KINASES; RNA, SMALL INTERFERING; SPHINGOSINE;

EID: 84855471690     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.142     Document Type: Article

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