Pigment epithelium-derived factor inhibits fibroblast-growth-factor-2-induced capillary morphogenesis of endothelial cells through Fyn

Journal of Cell Science

Volumn 118, Issue 5, 2005, Pages 961-970

  Kanda, Shigeru ^a   Mochizuki, Yasushi ^b   Nakamura, Takao ^b   Miyata, Yasuyoshi ^b   Matsuyama, Toshifumi ^a   Kanetake, Hiroshi ^b  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

Capillary morphogenesis; Endothelial cells; Fes; FGF 2; Fyn; PEDF

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; FIBROBLAST GROWTH FACTOR 2; MATRIGEL; PIGMENT EPITHELIUM DERIVED FACTOR; PROTEIN KINASE FYN;

ANIMAL CELL; ANTIANGIOGENIC ACTIVITY; ARTICLE; BRAIN CAPILLARY; CAPILLARY ENDOTHELIUM; CAPILLARY PROLIFERATION; CARBOXY TERMINAL SEQUENCE; CELL CULTURE; CELL LINE; CULTURE MEDIUM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; UMBILICAL VEIN; WILD TYPE;

ANIMALS; BRAIN; CAPILLARIES; CELLS, CULTURED; COLLAGEN; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; DOWN-REGULATION; DRUG COMBINATIONS; ENDOTHELIUM, VASCULAR; EYE PROTEINS; FIBROBLAST GROWTH FACTOR 2; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GTPASE-ACTIVATING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LAMININ; MICE; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; NERVE GROWTH FACTORS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEOGLYCANS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FYN; PYRIMIDINES; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; SERPINS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TRANSFECTION; TYROSINE; UMBILICAL VEINS;

ANIMALIA; MURINAE;

EID: 16844375174     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.01686     Document Type: Article

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