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Volumn 14, Issue 1, 2012, Pages

Evidence that GTP-binding domain but not catalytic domain of transglutaminase 2 is essential for epithelial-to-mesenchymal transition in mammary epithelial cells

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MUTANT PROTEIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; GUANINE NUCLEOTIDE BINDING PROTEIN; HOMEODOMAIN PROTEIN; NUCLEAR PROTEIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TWIST; TWIST1 PROTEIN, HUMAN; ZEB1 PROTEIN, HUMAN;

EID: 84855468654     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr3085     Document Type: Article
Times cited : (51)

References (40)
  • 1
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • 10.1016/j.cell.2009.11.007, 19945376
    • Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009, 139:871-890. 10.1016/j.cell.2009.11.007, 19945376.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 2
    • 67651005404 scopus 로고    scopus 로고
    • EMT: when epithelial cells decide to become mesenchymal-like cells
    • 10.1172/JCI39675, 2689122, 19487817
    • Kalluri R. EMT: when epithelial cells decide to become mesenchymal-like cells. J Clin Invest 2009, 119:1417-1419. 10.1172/JCI39675, 2689122, 19487817.
    • (2009) J Clin Invest , vol.119 , pp. 1417-1419
    • Kalluri, R.1
  • 3
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • 10.1172/JCI39104, 2689101, 19487818
    • Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest 2009, 119:1420-1428. 10.1172/JCI39104, 2689101, 19487818.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 5
    • 9744274000 scopus 로고    scopus 로고
    • Prognostic significance of tissue transglutaminase in drug resistant and metastatic breast cancer
    • 10.1158/1078-0432.CCR-04-1107, 15585642
    • Mehta K, Fok J, Miller FR, Koul D, Sahin AA. Prognostic significance of tissue transglutaminase in drug resistant and metastatic breast cancer. Clin Cancer Res 2004, 10:8068-8076. 10.1158/1078-0432.CCR-04-1107, 15585642.
    • (2004) Clin Cancer Res , vol.10 , pp. 8068-8076
    • Mehta, K.1    Fok, J.2    Miller, F.R.3    Koul, D.4    Sahin, A.A.5
  • 6
    • 34247153086 scopus 로고    scopus 로고
    • Tissue transglutaminase expression promotes cell attachment, invasion and survival in breast cancer cells
    • 10.1038/sj.onc.1210035, 17043648
    • Mangala LS, Fok JY, Zorrilla-Calancha IR, Verma A, Mehta K. Tissue transglutaminase expression promotes cell attachment, invasion and survival in breast cancer cells. Oncogene 2007, 26:2459-2470. 10.1038/sj.onc.1210035, 17043648.
    • (2007) Oncogene , vol.26 , pp. 2459-2470
    • Mangala, L.S.1    Fok, J.Y.2    Zorrilla-Calancha, I.R.3    Verma, A.4    Mehta, K.5
  • 7
    • 78149462058 scopus 로고    scopus 로고
    • Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells
    • 10.1371/journal.pone.0013390, 2953521, 20967228
    • Kumar A, Xu J, Brady S, Gao H, Yu D, Reuben J, Mehta K. Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells. PLoS One 2010, 5:e13390. 10.1371/journal.pone.0013390, 2953521, 20967228.
    • (2010) PLoS One , vol.5
    • Kumar, A.1    Xu, J.2    Brady, S.3    Gao, H.4    Yu, D.5    Reuben, J.6    Mehta, K.7
  • 8
    • 79958109319 scopus 로고    scopus 로고
    • Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells
    • 10.1371/journal.pone.0020701, 3110765, 21687668
    • Kumar A, Gao H, Xu J, Reuben J, Yu D, Mehta K. Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells. PLoS One 2011, 6:e20701. 10.1371/journal.pone.0020701, 3110765, 21687668.
    • (2011) PLoS One , vol.6
    • Kumar, A.1    Gao, H.2    Xu, J.3    Reuben, J.4    Yu, D.5    Mehta, K.6
  • 9
    • 33744496065 scopus 로고    scopus 로고
    • Transglutaminase 2 in inflammation
    • 10.2741/2030, 16720373
    • Kim SY. Transglutaminase 2 in inflammation. Front Biosci 2006, 11:3026-3035. 10.2741/2030, 16720373.
    • (2006) Front Biosci , vol.11 , pp. 3026-3035
    • Kim, S.Y.1
  • 10
    • 34447286702 scopus 로고    scopus 로고
    • Transglutaminase 2 inhibitors and their therapeutic role in disease states
    • 10.1016/j.pharmthera.2007.05.003, 1975782, 17582505
    • Siegel M, Khosla C. Transglutaminase 2 inhibitors and their therapeutic role in disease states. Pharmacol Ther 2007, 115:232-245. 10.1016/j.pharmthera.2007.05.003, 1975782, 17582505.
    • (2007) Pharmacol Ther , vol.115 , pp. 232-245
    • Siegel, M.1    Khosla, C.2
  • 11
    • 33746041843 scopus 로고    scopus 로고
    • Implications of tissue transglutaminase expression in malignant melanoma
    • 10.1158/1535-7163.MCT-06-0083, 16818508
    • Fok JY, Ekmekcioglu S, Mehta K. Implications of tissue transglutaminase expression in malignant melanoma. Mol Cancer Ther 2006, 5:1493-1503. 10.1158/1535-7163.MCT-06-0083, 16818508.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1493-1503
    • Fok, J.Y.1    Ekmekcioglu, S.2    Mehta, K.3
  • 12
    • 33751285778 scopus 로고    scopus 로고
    • Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis
    • 10.1158/0008-5472.CAN-06-2387, 17079475
    • Verma A, Wang H, Manavathi B, Fok JY, Mann A, Kumar R, Mehta K. Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis. Cancer Res 2006, 66:10525-10533. 10.1158/0008-5472.CAN-06-2387, 17079475.
    • (2006) Cancer Res , vol.66 , pp. 10525-10533
    • Verma, A.1    Wang, H.2    Manavathi, B.3    Fok, J.Y.4    Mann, A.5    Kumar, R.6    Mehta, K.7
  • 15
    • 53349120661 scopus 로고    scopus 로고
    • Tissue transglutaminase 2 expression in meningiomas
    • 10.1007/s11060-008-9642-1, 18587533
    • Yuan L, Behdad A, Siegel M, Khosla C, Higashikubo R, Rich KM. Tissue transglutaminase 2 expression in meningiomas. J Neurooncol 2008, 90:125-132. 10.1007/s11060-008-9642-1, 18587533.
    • (2008) J Neurooncol , vol.90 , pp. 125-132
    • Yuan, L.1    Behdad, A.2    Siegel, M.3    Khosla, C.4    Higashikubo, R.5    Rich, K.M.6
  • 16
    • 34548848815 scopus 로고    scopus 로고
    • Tissue transglutaminase-mediated chemoresistance in cancer cells
    • 10.1016/j.drup.2007.06.002, 17662645
    • Verma A, Mehta K. Tissue transglutaminase-mediated chemoresistance in cancer cells. Drug Resist Updat 2007, 10:144-151. 10.1016/j.drup.2007.06.002, 17662645.
    • (2007) Drug Resist Updat , vol.10 , pp. 144-151
    • Verma, A.1    Mehta, K.2
  • 17
    • 33644668017 scopus 로고    scopus 로고
    • Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas
    • 10.1158/1535-7163.MCT-04-0328, 16170020
    • Yuan L, Choi K, Khosla C, Zheng X, Higashikubo R, Chicoine MR, Rich KM. Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas. Mol Cancer Ther 2005, 4:1293-1302. 10.1158/1535-7163.MCT-04-0328, 16170020.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1293-1302
    • Yuan, L.1    Choi, K.2    Khosla, C.3    Zheng, X.4    Higashikubo, R.5    Chicoine, M.R.6    Rich, K.M.7
  • 18
    • 67651246845 scopus 로고    scopus 로고
    • Intracellular localization and conformational state of transglutaminase 2: implications for cell death
    • 10.1371/journal.pone.0006123, 2701606, 19568436
    • Gundemir S, Johnson GV. Intracellular localization and conformational state of transglutaminase 2: implications for cell death. PLoS One 2009, 4:e6123. 10.1371/journal.pone.0006123, 2701606, 19568436.
    • (2009) PLoS One , vol.4
    • Gundemir, S.1    Johnson, G.V.2
  • 19
    • 33646858986 scopus 로고    scopus 로고
    • Implications of increased tissue transglutaminase (TG2) expression in drug-resistant breast cancer (MCF-7) cells
    • 10.1038/sj.onc.1209324, 16449978
    • Herman JF, Mangala LS, Mehta K. Implications of increased tissue transglutaminase (TG2) expression in drug-resistant breast cancer (MCF-7) cells. Oncogene 2006, 25:3049-3058. 10.1038/sj.onc.1209324, 16449978.
    • (2006) Oncogene , vol.25 , pp. 3049-3058
    • Herman, J.F.1    Mangala, L.S.2    Mehta, K.3
  • 20
    • 33748988771 scopus 로고    scopus 로고
    • Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-κB in cancer cells: delineation of a novel pathway
    • 10.1158/0008-5472.CAN-06-1457, 16951195
    • Mann AP, Verma A, Sethi G, Manavathi B, Wang H, Fok JY, Kunnumakkara AB, Kumar R, Aggarwal BB, Mehta K. Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-κB in cancer cells: delineation of a novel pathway. Cancer Res 2006, 66:8788-8795. 10.1158/0008-5472.CAN-06-1457, 16951195.
    • (2006) Cancer Res , vol.66 , pp. 8788-8795
    • Mann, A.P.1    Verma, A.2    Sethi, G.3    Manavathi, B.4    Wang, H.5    Fok, J.Y.6    Kunnumakkara, A.B.7    Kumar, R.8    Aggarwal, B.B.9    Mehta, K.10
  • 21
    • 0347413734 scopus 로고    scopus 로고
    • Stem cells in normal breast development and breast cancer
    • 10.1046/j.1365-2184.36.s.1.6.x, 14521516
    • Dontu G, Al-Hajj M, Abdallah WM, Clarke MF, Wicha MS. Stem cells in normal breast development and breast cancer. Cell Prolif 2003, 36:59-72. 10.1046/j.1365-2184.36.s.1.6.x, 14521516.
    • (2003) Cell Prolif , vol.36 , pp. 59-72
    • Dontu, G.1    Al-Hajj, M.2    Abdallah, W.M.3    Clarke, M.F.4    Wicha, M.S.5
  • 22
    • 0026425631 scopus 로고
    • Tumor invasion and metastasis: an imbalance of positive and negative regulation
    • Liotta LA, Stetler-Stevenson WG. Tumor invasion and metastasis: an imbalance of positive and negative regulation. Cancer Res 1991, 51(18 Suppl):5054s-5059s.
    • (1991) Cancer Res , vol.51 , Issue.18 SUPPL
    • Liotta, L.A.1    Stetler-Stevenson, W.G.2
  • 23
    • 2642595021 scopus 로고
    • Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma
    • 10.1073/pnas.77.2.1039, 348419, 6928659
    • Cifone MA, Fidler IJ. Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma. Proc Natl Acad Sci USA 1980, 77:1039-1043. 10.1073/pnas.77.2.1039, 348419, 6928659.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 1039-1043
    • Cifone, M.A.1    Fidler, I.J.2
  • 24
    • 33845307265 scopus 로고    scopus 로고
    • Reversal of drug resistance in breast cancer cells by transglutaminase 2 inhibition and nuclear factor-κB inactivation
    • 10.1158/0008-5472.CAN-06-1521, 17108131
    • Kim DS, Park SS, Nam BH, Kim IH, Kim SY. Reversal of drug resistance in breast cancer cells by transglutaminase 2 inhibition and nuclear factor-κB inactivation. Cancer Res 2006, 66:10936-10943. 10.1158/0008-5472.CAN-06-1521, 17108131.
    • (2006) Cancer Res , vol.66 , pp. 10936-10943
    • Kim, D.S.1    Park, S.S.2    Nam, B.H.3    Kim, I.H.4    Kim, S.Y.5
  • 25
    • 73649115337 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition and ovarian tumor progression induced by tissue transglutaminase
    • 10.1158/0008-5472.CAN-09-1257, 19951993
    • Shao M, Cao L, Shen C, Satpathy M, Chelladurai B, Bigsby RM, Nakshatri H, Matei D. Epithelial-to-mesenchymal transition and ovarian tumor progression induced by tissue transglutaminase. Cancer Res 2009, 69:9192-9201. 10.1158/0008-5472.CAN-09-1257, 19951993.
    • (2009) Cancer Res , vol.69 , pp. 9192-9201
    • Shao, M.1    Cao, L.2    Shen, C.3    Satpathy, M.4    Chelladurai, B.5    Bigsby, R.M.6    Nakshatri, H.7    Matei, D.8
  • 26
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • 10.1038/nrc822, 12189386
    • Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002, 2:442-454. 10.1038/nrc822, 12189386.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 27
    • 78049427740 scopus 로고    scopus 로고
    • Transglutaminase 2: a multi-tasking protein in the complex circuitry of inflammation and cancer
    • 10.1016/j.bcp.2010.06.029, 20599779
    • Mehta K, Kumar A, Kim HI. Transglutaminase 2: a multi-tasking protein in the complex circuitry of inflammation and cancer. Biochem Pharmacol 2010, 80:1921-1929. 10.1016/j.bcp.2010.06.029, 20599779.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1921-1929
    • Mehta, K.1    Kumar, A.2    Kim, H.I.3
  • 28
    • 67650928193 scopus 로고    scopus 로고
    • Tissue transglutaminase promotes or suppresses tumors depending on cell context
    • Chhabra A, Verma A, Mehta K. Tissue transglutaminase promotes or suppresses tumors depending on cell context. Anticancer Res 2009, 29:1909-1919.
    • (2009) Anticancer Res , vol.29 , pp. 1909-1919
    • Chhabra, A.1    Verma, A.2    Mehta, K.3
  • 29
    • 79551600015 scopus 로고    scopus 로고
    • Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
    • 10.1038/nrclinonc.2010.196, 21151206
    • Takebe N, Harris PJ, Warren RQ, Ivy SP. Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Oncol 2011, 8:97-106. 10.1038/nrclinonc.2010.196, 21151206.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 97-106
    • Takebe, N.1    Harris, P.J.2    Warren, R.Q.3    Ivy, S.P.4
  • 30
    • 79551615954 scopus 로고    scopus 로고
    • Cytosolic guanine nucleotide binding deficient form of transglutaminase 2 (R580A) potentiates cell death in oxygen glucose deprivation
    • 10.1371/journal.pone.0016665, 3031627, 21304968
    • Colak G, Keillor JW, Johnson JVW. Cytosolic guanine nucleotide binding deficient form of transglutaminase 2 (R580A) potentiates cell death in oxygen glucose deprivation. PLoS One 2011, 6:e16665. 10.1371/journal.pone.0016665, 3031627, 21304968.
    • (2011) PLoS One , vol.6
    • Colak, G.1    Keillor, J.W.2    Johnson, J.V.W.3
  • 32
    • 0037022619 scopus 로고    scopus 로고
    • Structural basis for the guanine nucleotide binding activity of tissue transglutaminase and its regulation of transamidation activity
    • 10.1073/pnas.042454899, 122418, 11867708
    • Liu S, Cerione RA, Clardy J. Structural basis for the guanine nucleotide binding activity of tissue transglutaminase and its regulation of transamidation activity. Proc Natl Acad Sci USA 2002, 99:2743-2747. 10.1073/pnas.042454899, 122418, 11867708.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2743-2747
    • Liu, S.1    Cerione, R.A.2    Clardy, J.3
  • 33
    • 0037317032 scopus 로고    scopus 로고
    • Transglutaminases: crosslinking enzymes with pleiotropic functions
    • 10.1038/nrm1014, 12563291
    • Lorand L, Graham RM. Transglutaminases: crosslinking enzymes with pleiotropic functions. Nat Rev Mol Cell Biol 2003, 4:140-156. 10.1038/nrm1014, 12563291.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 140-156
    • Lorand, L.1    Graham, R.M.2
  • 34
    • 77954861745 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer
    • Creighton CJ, Chang JC, Rosen JM. Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer. Neoplasia 2010, 15:253-260.
    • (2010) Neoplasia , vol.15 , pp. 253-260
    • Creighton, C.J.1    Chang, J.C.2    Rosen, J.M.3
  • 35
    • 77956178360 scopus 로고    scopus 로고
    • EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
    • 10.1038/onc.2010.215, 3176718, 20531305
    • Singh A, Settleman J. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 2010, 29:4741-4751. 10.1038/onc.2010.215, 3176718, 20531305.
    • (2010) Oncogene , vol.29 , pp. 4741-4751
    • Singh, A.1    Settleman, J.2
  • 36
    • 53949090765 scopus 로고    scopus 로고
    • NF-κB signaling pathway and its therapeutic implications in human diseases
    • 10.1080/08830180802276179, 18853341
    • Sarkar FH, Li Y, Wang Z, Kong D. NF-κB signaling pathway and its therapeutic implications in human diseases. Int Rev Immunol 2008, 27:293-319. 10.1080/08830180802276179, 18853341.
    • (2008) Int Rev Immunol , vol.27 , pp. 293-319
    • Sarkar, F.H.1    Li, Y.2    Wang, Z.3    Kong, D.4
  • 37
    • 0036546501 scopus 로고    scopus 로고
    • NF-κB in cancer: from innocent bystander to major culprit
    • 10.1038/nrc780, 12001991
    • Karin M, Cao Y, Greten FR, Li ZW. NF-κB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002, 2:301-310. 10.1038/nrc780, 12001991.
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 38
    • 45149092780 scopus 로고    scopus 로고
    • NF-κB and epithelial to mesenchymal transition of cancer
    • 10.1002/jcb.21695, 18253935
    • Min C, Eddy SF, Sherr DH, Sonenshein GE. NF-κB and epithelial to mesenchymal transition of cancer. J Cell Biochem 2008, 104:733-744. 10.1002/jcb.21695, 18253935.
    • (2008) J Cell Biochem , vol.104 , pp. 733-744
    • Min, C.1    Eddy, S.F.2    Sherr, D.H.3    Sonenshein, G.E.4
  • 39
    • 0023766055 scopus 로고    scopus 로고
    • Associations of human erythrocyte band 4.2: binding to ankyrin and to the cytoplasmic domain of band 3
    • Korsgren C, Cohen CM. Associations of human erythrocyte band 4.2: binding to ankyrin and to the cytoplasmic domain of band 3. J Biol Chem 1998, 263:10212-10218.
    • (1998) J Biol Chem , vol.263 , pp. 10212-10218
    • Korsgren, C.1    Cohen, C.M.2


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