Association analyses of variants in the DIO2 gene with early-onset type 2 diabetes mellitus in Pima Indians

Thyroid

Volumn 22, Issue 1, 2012, Pages 80-87

  Nair, Saraswathy ^a,b   Muller, Yunhua Li ^a   Ortega, Emilio ^a,c   Kobes, Sayuko ^a   Bogardus, Clifton ^a   Baier, Leslie J ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b UNIVERSITY OF TEXAS AT BROWNSVILLE   (United States)

^c HOSPITAL CLÍNIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; DIO2 GENE; ENERGY EXPENDITURE; GENE; GENE LINKAGE DISEQUILIBRIUM; GENE SEQUENCE; GENETIC VARIABILITY; GENOTYPE; HUMAN; INDIAN; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGE OF ONSET; BODY MASS INDEX; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INDIANS, NORTH AMERICAN; IODIDE PEROXIDASE; LINKAGE DISEQUILIBRIUM; OBESITY, MORBID; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84855434355     PISSN: 10507256     EISSN: 15579077     Source Type: Journal    
DOI: 10.1089/thy.2010.0455     Document Type: Article

References (42)

1. Danforth E Jr 1983 The role of thyroid hormones and insulin in the regulation of energy metabolism. Am J Clin Nutr 38:1006-1017. (Pubitemid 14201118)
2. Krotkiewski M 2002 Thyroid hormones in the pathogenesis and treatment of obesity. Eur J Pharmacol 440:85-98. (Pubitemid 34458016)
3. Silva JE 1995 Thyroid hormone control of thermogenesis and energy balance. Thyroid 5:481-492. (Pubitemid 26036911)
4. Freake HC, Oppenheimer JH 1995 Thermogenesis and thyroid function. Annu Rev Nutr 15:263-291.
5. Silva JE 2003 The thermogenic effect of thyroid hormone and its clinical implications. Ann Intern Med 139:205-213. (Pubitemid 38124603)
6. Lanni A, Moreno M, Lombardi A, Goglia F 2003 Thyroid hormone and uncoupling proteins. FEBS Lett 543:5-10. (Pubitemid 36577217)
7. Bianco AC, Maia AL, da Silva WS, Christoffolete MA 2005 Adaptive activation of thyroid hormone and energy expenditure. Biosci Rep 25:191-208. (Pubitemid 41613787)
8. Chidakel A, Mentuccia D, Celi FS 2005 Peripheral metabolism of thyroid hormone and glucose homeostasis. Thyroid 15:899-903. (Pubitemid 41339268)
9. Kim SR, Tull ES, Talbott EO, Vogt MT, Kuller LH 2002 A hypothesis of synergism: the interrelationship of T3 and insulin to disturbances in metabolic homeostasis. Med Hypotheses 59:660-666. (Pubitemid 35463451)
10. Dubaniewicz A, Kaciuba-Uscilko H, Nazar K, Budohoski L 1989 Sensitivity of the soleus muscle to insulin in resting and exercising rats with experimental hypo- and hyper-thyroidism. Biochem J 263:243-247. (Pubitemid 19243837)
11. Dimitriadis G, Baker B, Marsh H, Mandarino L, Rizza R, Bergman R, Haymond M, Gerich J 1985 Effect of thyroid hormone excess on action, secretion, and metabolism of insulin in humans. Am J Physiol 248:E593-E601. (Pubitemid 15018379)
12. Rochon C, Tauveron I, Dejax C, Benoit P, Capitan P, Fabricio A, Berry C, Champredon C, Thieblot P, Grizard J 2003 Response of glucose disposal to hyperinsulinaemia in human hypothyroidism and hyperthyroidism. Clin Sci (Lond) 104:7-15. (Pubitemid 36249918)
13. Torrance CJ, Devente JE, Jones JP, Dohm GL 1997 Effects of thyroid hormone on GLUT4 glucose transporter gene expression and NIDDM in rats. Endocrinology 138:1204-1214. (Pubitemid 27089779)
14. Shimizu Y, Shimazu T 2002 Thyroid hormone augments GLUT4 expression and insulin-sensitive glucose transport system in differentiating rat brown adipocytes in culture. J Vet Med Sci 64:677-681.
15. Tuzcu A, Bahceci M, Gokalp D, Tuzun Y, Gunes K 2005 Subclinical hypothyroidism may be associated with elevated high-sensitive c-reactive protein (low grade inflammation) and fasting hyperinsulinemia. Endocr J 52:89-94. (Pubitemid 40410323)
16. Bianco AC, Salvatore D, Gereben B, Berry MJ, Larsen PR 2002 Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev 23:38-89. (Pubitemid 34185306)
17. Bianco AC, Larsen PR 2005 Cellular and structural biology of the deiodinases. Thyroid 15:777-786. (Pubitemid 41339258)
18. Bartha T, Kim SW, Salvatore D, Gereben B, Tu HM, Harney JW, Rudas P, Larsen PR 2000 Characterization of the 5'- flanking and 5'-untranslated regions of the cyclic adenosine 3',5'-monophosphate-responsive human type 2 iodothyronine deiodinase gene. Endocrinology 141:229-237. (Pubitemid 32260363)
19. Silva JE, Larsen PR 1983 Adrenergic activation of triiodothyronine production in brown adipose tissue. Nature 305:712-713. (Pubitemid 13021520)
20. Maia AL, Kim BW, Huang SA, Harney JW, Larsen PR 2005 Type 2 iodothyronine deiodinase is the major source of plasma T3 in euthyroid humans. J Clin Invest 115:2524-2533. (Pubitemid 41266215)
21. Mentuccia D, Proietti-Pannunzi L, Tanner K, Bacci V, Pollin TI, Poehlman ET, Shuldiner AR, Celi FS 2002 Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: evidence of interaction with the Trp64Arg variant of the beta-3-adrenergic receptor. Diabetes 51:880-883. (Pubitemid 34760206)
22. Grarup N, Andersen MK, Andreasen CH, Albrechtsen A, Borch-Johnsen K, Jorgensen T, Auwerx J, Schmitz O, Hansen T, Pedersen O 2007 Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects. J Clin Endocrinol Metab 92:363-366. (Pubitemid 46067554)
23. Canani LH, Capp C, Dora JM, Meyer FL, Wagner MS, Harney JW, Larsen PR, Gross JL, Bianco AC, Maia AL 2005 The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 90:3472-3478. (Pubitemid 41014316)
24. Dora JM, Machado WE, Rheinheimer J, Crispim D, Maia AL 2010 Association of the type 2 deiodinase Thr92Ala polymorphism with type 2 diabetes: case-control study and meta-analysis. Eur J Endocrinol 163:427-434.
25. Canani LH, Leie MA, Machado WE, Capp C, Maia AL 2007 Type 2 deiodinase Thr92Ala polymorphism is not associated with arterial hypertension in type 2 diabetes mellitus patients. Hypertension 49:E47. (Pubitemid 46809405)
26. Maia AL, Dupuis J, Manning A, Liu C, Meigs JB, Cupples LA, Larsen PR, Fox CS 2007 The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the framingham heart study. Thyroid 17:199-202. (Pubitemid 46557366)
27. Mentuccia D, Thomas MJ, Coppotelli G, Reinhart LJ, Mitchell BD, Shuldiner AR, Celi FS 2005 The Thr92Ala deiodinase type 2 (DIO2) variant is not associated with type 2 diabetes or indices of insulin resistance in the old order of Amish. Thyroid 15:1223-1227. (Pubitemid 41821754)
28. Knowler WC, Bennett PH, Hamman RF, Miller M 1978 Diabetes incidence and prevalence in Pima Indians: a 19-fold greater incidence than in Rochester, Minnesota. Am J Epidemiol 108:497-505. (Pubitemid 9147733)
29. Baier LJ, Permana PA, Traurig M, Dobberfuhl A, Weidrich C, Sutherland J, Thuillez P, Luczy-Bachman G, Hara M, Horikawa Y, Hinokio Y, Hanson RL, Bogardus C 2000 Mutations in the genes for hepatocyte nuclear factor (HNF)- 1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians. Diabetes Care 23:302-304. (Pubitemid 30131734)
30. Ma L, Tataranni PA, Hanson RL, Infante AM, Kobes S, Bogardus C, Baier LJ 2005 Variations in peptide YY and Y2 receptor genes are associated with severe obesity in Pima Indian men. Diabetes 54:1598-1602. (Pubitemid 40586696)
31. Hanson RL, Ehm MG, Pettitt DJ, Prochazka M, Thompson DB, Timberlake DB, Foroud T, Kobes S, Baier L, Burns DK, Almasy L, Blangero J, Garvey WT, Bennett PH, Knowler WC 1998 An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians. Am J Hum Genet 63:1130-1138. (Pubitemid 30418584)
32. Dabelea D, Palmer JP, Bennett PH, Pettitt DJ, Knowler WC 1999 Absence of glutamic acid decarboxylase antibodies in Pima Indian children with diabetes mellitus. Diabetologia 42:1265-1266. (Pubitemid 29459827)
33. Anonymous 1985 Diabetes mellitus. Report of a WHO Study Group. World Health Organ Tech Rep Ser 727:1-113.
34. Tataranni PA, Ravussin E 1995 Use of dual-energy X-ray absorptiometry in obese individuals. Am J Clin Nutr 62:730-734.
35. Lillioja S, Mott DM, Zawadzki JK, Young AA, Abbott WG, Knowler WC, Bennett PH, Moll P, Bogardus C 1987 In vivo insulin action is familial characteristic in nondiabetic Pima Indians. Diabetes 36:1329-1335. (Pubitemid 17163996)
36. SteeleR1959Influencesofglucoseloadingandof injectedinsulin on hepatic glucose output.AnnNYAcad Sci 82:420-430.
37. Ravussin E, Lillioja S, Anderson TE, Christin L, Bogardus C 1986 Determinants of 24-hour energy expenditure in man. Methods and results using a respiratory chamber. J Clin Invest 78:1568-1578. (Pubitemid 17219520)
38. Hanson RL, Elston RC, Pettitt DJ, Bennett PH, Knowler WC 1995 Segregation analysis of non-insulin-dependent diabetes mellitus in Pima Indians: evidence for a major-gene effect. Am J Hum Genet 57:160-170.
39. Clement K, Vaisse C, Manning BS, Basdevant A, Guy-Grand B, Ruiz J, Silver KD, Shuldiner AR, Froguel P, Strosberg AD 1995 Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity. N Engl J Med 333:352-354.
40. Walston J, Silver K, Bogardus C, Knowler WC, Celi FS, Austin S, Manning B, Strosberg AD, Stern MP, Raben N, Sorkin JD, Roth J, Shuldiner A 1995 Time of onset of non-insulin-dependent diabetes mellitus and genetic variation in the beta 3-adrenergic-receptor gene. N Engl J Med 333: 343-347.
41. Feng X, Jiang Y, Meltzer P, Yen PM 2000 Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray. Mol Endocrinol 14:947-955. (Pubitemid 32250513)
42. Ortega E, Pannacciulli N, Bogardus C, Krakoff J 2007 Plasma concentrations of free triiodothyronine predict weight change in euthyroid persons. Am J Clin Nutr 85:440-445. (Pubitemid 46220946)