Regulation of insulin gene transcription by multiple histone acetyltransferases

DNA and Cell Biology

Volumn 31, Issue 1, 2012, Pages 8-14

  Sampley, Megan L ^a   Özcan, Sabire ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLUCOSE; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; INSULIN; PROTEIN P300; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CGN5; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ANIMAL CELL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HISTONE ACETYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; TRANSCRIPTION REGULATION;

ACETYLATION; ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; CREB-BINDING PROTEIN; GLUCOSE; HISTONES; INSULIN; INSULINOMA; MICE; P300-CBP TRANSCRIPTION FACTORS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSCRIPTION, GENETIC;

EID: 84855430217     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2011.1336     Document Type: Article

References (39)

1. Andrali, S.S., Sampley, M.L., Vanderford, N.L., and Ozcan, S. (2008). Glucose regulation of insulin gene expression in pancreatic beta-cells. Biochem J 415, 1-10.
2. Asahara, H., Dutta, S., Kao, H.Y., Evans, R.M., and Montminy, M. (1999). Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner. Mol Cell Biol 19, 8219-8225. (Pubitemid 30414016)
3. Caton, P.W., Nayuni, N., Kieswich, J., Khan, N., Yaqoob, M., and Corder, R. (2010). Metformin suppresses hepatic gluconeogenesis through induction of SIRT1 and GCN5. J Endocrinol 205, 97-106.
4. Chakrabarti, S.K., Francis, J., Ziesmann, S.M., Garmey, J.C., and Mirmira, R.G. (2003). Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic beta cells. J Biol Chem 278, 23617-23623. (Pubitemid 36830183)
5. Chakrabarti, S.K., James, J.C., and Mirmira, R.G. (2002). Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding. J Biol Chem 277, 13286-13293. (Pubitemid 34952700)
6. Christenson, L.K., Stouffer, R.L., and Strauss, J.F., 3rd. (2001). Quantitative analysis of the hormone-induced hyperacetylation of histone H3 associated with the steroidogenic acute regulatory protein gene promoter. J Biol Chem 276, 27392-27399.
7. Deering, T.G., Ogihara, T., Trace, A.P., Maier, B., and Mirmira, R.G. (2009). Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes. Diabetes 58, 185-193.
8. Dominy, J.E., Jr., Lee, Y., Gerhart-Hines, Z., and Puigserver, P. (2010). Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5. Biochim Biophys Acta 1804, 1676-1683.
9. Evans-Molina, C., Garmey, J.C., Ketchum, R., Brayman, K.L., Deng, S., and Mirmira, R.G. (2007). Glucose regulation of insulin gene transcription and pre-mRNA processing in human islets. Diabetes 56, 827-835. (Pubitemid 46348457)
10. Finlin, B.S., Mosley, A.L., Crump, S.M., Correll, R.N., Ozcan, S., Satin, J., and Andres, D.A. (2005). Regulation of L-type Ca2 + channel activity and insulin secretion by the Rem2 GTPase. J Biol Chem 280, 41864-41871. (Pubitemid 43023155)
11. Francis, J., Chakrabarti, S.K., Garmey, J.C., and Mirmira, R.G. (2005). Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription. J Biol Chem 280, 36244-36253. (Pubitemid 41633897)
12. German, M., Ashcroft, S., Docherty, K., Edlund, H., Edlund, T., Goodison, S., Imura, H., Kennedy, G., Madsen, O., Melloul, D., et al. (1995). The insulin gene promoter. A simplified nomenclature. Diabetes 44, 1002-1004.
13. German, M.S., and Wang, J. (1994). The insulin gene contains multiple transcriptional elements that respond to glucose. Mol Cell Biol 14, 4067-4075. (Pubitemid 24160812)
14. Goodison, S., Kenna, S., and Ashcroft, S.J. (1992). Control of insulin gene expression by glucose. Biochem J 285 (Pt 2), 563-568.
15. Jeninga, E.H., Schoonjans, K., and Auwerx, J. (2010). Reversible acetylation of PGC-1: connecting energy sensors and effectors to guarantee metabolic flexibility. Oncogene 29, 4617-4624.
16. Kataoka, K., Han, S.I., Shioda, S., Hirai, M., Nishizawa, M., and Handa, H. (2002). MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene. J Biol Chem 277, 49903-49910. (Pubitemid 36014439)
17. Kelly, T.J., Lerin, C., Haas, W., Gygi, S.P., and Puigserver, P. (2009). GCN5-mediated transcriptional control of the metabolic coactivator PGC-1beta through lysine acetylation. J Biol Chem 284, 19945-19952.
18. Lerin, C., Rodgers, J.T., Kalume, D.E., Kim, S.H., Pandey, A., and Puigserver, P. (2006). GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha. Cell Metab 3, 429-438. (Pubitemid 43811779)
19. Liu, Y., and Montminy, M. (2006). CAT in the HAT: catabolic inhibition by the histone acetyltransferase GCN5. Cell Metab 3, 387-388. (Pubitemid 43811783)
20. Melloul, D., Ben-Neriah, Y., and Cerasi, E. (1993). Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters. Proc Natl Acad Sci U S A 90, 3865-3869. (Pubitemid 23134126)
21. Melloul, D., and Cerasi, E. (1994). Transcription of the insulin gene: towards defining the glucose-sensitive cis-element and trans-acting factors. Diabetologia 37 Suppl 2, S3-S10.
22. Melloul, D., Marshak, S., and Cerasi, E. (2002). Regulation of insulin gene transcription. Diabetologia 45, 309-326. (Pubitemid 34267353)
23. Miyazaki, J., Araki, K., Yamato, E., Ikegami, H., Asano, T., Shibasaki, Y., Oka, Y., and Yamamura, K. (1990). Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. Endocrinology 127, 126-132. (Pubitemid 20228111)
24. Mosley, A.L., Corbett, J.A., and Ozcan, S. (2004). Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1. Mol Endocrinol 18, 2279-2290. (Pubitemid 39215256)
25. Mosley, A.L., and Ozcan, S. (2003). Glucose regulates insulin gene transcription by hyperacetylation of histone H4. J Biol Chem 278, 19660-19666. (Pubitemid 36799150)
26. Mosley, A.L., and Ozcan, S. (2004). The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose. J Biol Chem 279, 54241-54247. (Pubitemid 40053161)
27. Naya, F.J., Huang, H.P., Qiu, Y., Mutoh, H., DeMayo, F.J., Leiter, A.B., and Tsai, M.J. (1997). Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev 11, 2323-2334. (Pubitemid 27408530)
28. Naya, F.J., Stellrecht, C.M., and Tsai, M.J. (1995). Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. Genes Dev 9, 1009-1019.
29. Olbrot, M., Rud, J., Moss, L.G., and Sharma, A. (2002). Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA. Proc Natl Acad Sci U S A 99, 6737-6742. (Pubitemid 34526201)
30. Peshavaria, M., Cissell, M.A., Henderson, E., Petersen, H.V., and Stein, R. (2000). The PDX-1 activation domain provides specific functions necessary for transcriptional stimulation in pancreatic beta-cells. Mol Endocrinol 14, 1907-1917. (Pubitemid 32055525)
31. Petersen, H.V., Serup, P., Leonard, J., Michelsen, B.K., and Madsen, O.D. (1994). Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/ IPF1 acting through the CT boxes. Proc Natl Acad Sci U S A 91, 10465-10469. (Pubitemid 24329018)
32. Qiu, Y., Guo, M., Huang, S., and Stein, R. (2004). Acetylation of the BETA2 transcription factor by p300-associated factor is important in insulin gene expression. J Biol Chem 279, 9796-9802. (Pubitemid 38372577)
33. Rocques, N., Abou Zeid, N., Sii-Felice, K., Lecoin, L., Felder-Schmittbuhl, M.P., Eychene, A., and Pouponnot, C. (2007). GSK-3-mediated phosphorylation enhances Maf-transforming activity. Mol Cell 28, 584-597. (Pubitemid 350137803)
34. Sharma, A., and Stein, R. (1994). Glucose-induced transcription of the insulin gene is mediated by factors required for betacell-type-specific expression. Mol Cell Biol 14, 871-879. (Pubitemid 24036536)
35. Vanderford, N.L., Andrali, S.S., and Ozcan, S. (2007). Glucose induces MafA expression in pancreatic beta cell lines via the hexosamine biosynthetic pathway. J Biol Chem 282, 1577-1584. (Pubitemid 47076679)
36. Walker, M.D., Edlund, T., Boulet, A.M., and Rutter, W.J. (1983). Cell-specific expression controlled by the 5'-flanking region of insulin and chymotrypsin genes. Nature 306, 557-561. (Pubitemid 14203819)
37. Wang, H.W., Breslin, M.B., and Lan, M.S. (2007). Pdx-1 modulates histone H4 acetylation and insulin gene expression in terminally differentiated alpha-TC-1 cells. Pancreas 34, 248-253. (Pubitemid 46294802)
38. Wellen, K.E., Hatzivassiliou, G., Sachdeva, U.M., Bui, T.V., Cross, J.R., and Thompson, C.B. (2009). ATP-citrate lyase links cellular metabolism to histone acetylation. Science 324, 1076-1080.
39. Zhang, T., Wang, H., Saunee, N.A., Breslin, M.B., and Lan, M.S. (2010). Insulinoma-associated antigen-1 zinc-finger transcription factor promotes pancreatic duct cell trans-differentiation. Endocrinology 151, 2030-2039.