Protein translocation through Tom40: Kinetics of peptide release

Biophysical Journal

Volumn 102, Issue 1, 2012, Pages 39-47

  Mahendran, Kozhinjampara R ^a   Romero Ruiz, Mercedes ^b   Schlösinger, Andrea ^b   Winterhalter, Mathias ^a   Nussberger, Stephan ^b  

^a JACOBS UNIVERSITY BREMEN   (Germany)

^b UNIVERSITY OF STUTTGART   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL PROTEIN; PEPTIDE; TOM40 PROTEIN, RAT;

ARTICLE; BINDING SITE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; KINETICS; MOTION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TRANSPORT; ULTRASTRUCTURE;

BINDING SITES; COMPUTER SIMULATION; KINETICS; MITOCHONDRIAL PROTEINS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOTION; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TRANSPORT;

EID: 84855426497     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2011.11.4003     Document Type: Article

References (44)

1. N. Pfanner, and A. Geissler Versatility of the mitochondrial protein import machinery Nat. Rev. Mol. Cell Biol. 2 2001 339 349 (Pubitemid 33674046)
2. W. Neupert, and J.M. Herrmann Translocation of proteins into mitochondria Annu. Rev. Biochem. 76 2007 723 749
3. D. Mokranjac, and W. Neupert Thirty years of protein translocation into mitochondria: unexpectedly complex and still puzzling Biochim. Biophys. Acta 1793 2009 33 41
4. E. Schleiff, and T. Becker Common ground for protein translocation: access control for mitochondria and chloroplasts Nat. Rev. Mol. Cell Biol. 12 2011 48 59
5. T. Endo, K. Yamano, and S. Kawano Structural insight into the mitochondrial protein import system Biochim. Biophys. Acta 1808 2011 955 970
6. D.J. du Plessis, N. Nouwen, and A.J. Driessen The Sec translocase Biochim. Biophys. Acta 1808 2011 851 865
7. C. Robinson, and C.F. Matos S. Mendel Transport and proofreading of proteins by the twin-arginine translocation (Tat) system in bacteria Biochim. Biophys. Acta 1808 2011 876 884
8. M.M. Mohammad, and L. Movileanu Excursion of a single polypeptide into a protein pore: simple physics, but complicated biology Eur. Biophys. J. 37 2008 913 925
9. L. Movileanu, and J.P. Schmittschmitt H. Bayley Interactions of peptides with a protein pore Biophys. J. 89 2005 1030 1045 (Pubitemid 41098986)
10. A.J. Wolfe, and M.M. Mohammad L. Movileanu Catalyzing the translocation of polypeptides through attractive interactions J. Am. Chem. Soc. 129 2007 14034 14041 (Pubitemid 350106096)
11. G. Oukhaled, and J. Mathé L. Auvray Unfolding of proteins and long transient conformations detected by single nanopore recording Phys. Rev. Lett. 98 2007 158101 158104
12. M. Pastoriza-Gallego, and L. Rabah J. Pelta Dynamics of unfolded protein transport through an aerolysin pore J. Am. Chem. Soc. 133 2011 2923 2931
13. A.R. Hall, and A. Scott C. Dekker Hybrid pore formation by directed insertion of α-haemolysin into solid-state nanopores Nat. Nanotechnol. 5 2010 874 877
14. K. Hill, and K. Model N. Pfanner Tom40 forms the hydrophilic channel of the mitochondrial import pore for preproteins [see comment] Nature 395 1998 516 521 (Pubitemid 28462448)
15. U. Ahting, and M. Thieffry S. Nussberger Tom40, the pore-forming component of the protein-conducting TOM channel in the outer membrane of mitochondria J. Cell Biol. 153 2001 1151 1160 (Pubitemid 34289255)
16. K. Model, C. Meisinger, and W. Kühlbrandt Cryo-electron microscopy structure of a yeast mitochondrial preprotein translocase J. Mol. Biol. 383 2008 1049 1057
17. F. Mager, L. Sokolova, J. Lintzel, B. Brutschy, and S. Nussberger LILBID-mass spectrometry of the mitochondrial preprotein translocase TOM J. Phys. Condens. Matter 22 2010 454132
18. A. Chacinska, and C.M. Koehler N. Pfanner Importing mitochondrial proteins: machineries and mechanisms Cell 138 2009 628 644
19. M. Thieffry, and J.F. Chich J.P. Henry Incorporation in lipid bilayers of a large conductance cationic channel from mitochondrial membranes EMBO J. 7 1988 1449 1454
20. F.M. Vallette, P. Juin, M. Pelleschi, and J.P. Henry Basic peptides can be imported into yeast mitochondria by two distinct targeting pathways. Involvement of the peptide-sensitive channel of the outer membrane J. Biol. Chem. 269 1994 13367 13374
21. C. Muro, and S.M. Grigoriev M.L. Campo Comparison of the TIM and TOM channel activities of the mitochondrial protein import complexes Biophys. J. 84 2003 2981 2989 (Pubitemid 36531749)
22. F. Fvre, J.P. Henry, and M. Thieffry Reversible and irreversible effects of basic peptides on the mitochondrial cationic channel Biophys. J. 66 1994 1887 1894 (Pubitemid 24167941)
23. K.P. Künkele, and P. Juin M. Thieffry The isolated complex of the translocase of the outer membrane of mitochondria. Characterization of the cation-selective and voltage-gated preprotein-conducting pore J. Biol. Chem. 273 1998 31032 31039 (Pubitemid 28533109)
24. L. Becker, and M. Bannwarth R. Wagner Preprotein translocase of the outer mitochondrial membrane: reconstituted Tom40 forms a characteristic TOM pore J. Mol. Biol. 353 2005 1011 1020 (Pubitemid 41503269)
25. U. Ahting, and C. Thun S. Nussberger The TOM core complex: the general protein import pore of the outer membrane of mitochondria J. Cell Biol. 147 1999 959 968
26. M. Romero-Ruiz, and K.R. Mahendran S. Nussberger Interactions of mitochondrial presequence peptides with the mitochondrial outer membrane preprotein translocase TOM Biophys. J. 99 2010 774 781
27. A. Harsmanm, and V. Krüger R. Wagner Protein conducting nanopores J. Phys. Condens. Matter 22 2010 454102
28. K.P. Künkele, and S. Heins W. Neupert The preprotein translocation channel of the outer membrane of mitochondria Cell 93 1998 1009 1019 (Pubitemid 28280794)
29. M. Poynor, R. Eckert, and S. Nussberger Dynamics of the preprotein translocation channel of the outer membrane of mitochondria Biophys. J. 95 2008 1511 1522
30. K.R. Mahendran, and C. Chimerel M. Winterhalter Antibiotic translocation through membrane channels: temperature-dependent ion current fluctuation for catching the fast events Eur. Biophys. J. 38 2009 1141 1145
31. H. Engelhardt, and T. Meins K. Zeth High-level expression, refolding and probing the natural fold of the human voltage-dependent anion channel isoforms I and II J. Membr. Biol. 216 2007 93 105 (Pubitemid 47479553)
32. T. Arnold, and M. Poynor D. Linke Gene duplication of the eight-stranded β-barrel OmpX produces a functional pore: a scenario for the evolution of transmembrane β-barrels J. Mol. Biol. 366 2007 1174 1184 (Pubitemid 46186395)
33. S. Nekolla, C. Andersen, and R. Benz Noise analysis of ion current through the open and the sugar-induced closed state of the LamB channel of Escherichia coli outer membrane: evaluation of the sugar binding kinetics to the channel interior Biophys. J. 66 1994 1388 1397 (Pubitemid 24145136)
34. A. Mayer, W. Neupert, and R. Lill Mitochondrial protein import: reversible binding of the presequence at the trans side of the outer membrane drives partial translocation and unfolding Cell 80 1995 127 137
35. A. Vasiljev, and U. Ahting D. Rapaport Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes Mol. Biol. Cell 15 2004 1445 1458 (Pubitemid 38316250)
36. S. Schmitt, and U. Ahting S. Nussberger Role of Tom5 in maintaining the structural stability of the TOM complex of mitochondria J. Biol. Chem. 280 2005 14499 14506 (Pubitemid 40562791)
37. O. Schmidt, and A. Harbauer C. Meisinger Regulation of mitochondrial protein import by cytosolic kinases Cell 144 2011 227 239
38. R. Bikwemu, A.J. Wolfe, X. Xing, and L. Movileanu Facilitated translocation of polypeptides through a single nanopore J. Phys. Condens. Matter 22 2010 454117
39. H. Meng, and D. Detillieux J.S. Lee Nanopore analysis of tethered peptides J. Pept. Sci. 16 2010 701 708
40. T. Stan, and U. Ahting D. Rapaport Recognition of preproteins by the isolated TOM complex of mitochondria EMBO J. 19 2000 4895 4902
41. V.V. Lemeshko Model of the outer membrane potential generation by the inner membrane of mitochondria Biophys. J. 82 2002 684 692 (Pubitemid 34111210)
42. V.V. Lemeshko Theoretical evaluation of a possible nature of the outer membrane potential of mitochondria Eur. Biophys. J. 36 2006 57 66 (Pubitemid 44736052)
43. R. Benz, M. Kottke, and D. Brdiczka The cationically selective state of the mitochondrial outer membrane pore: a study with intact mitochondria and reconstituted mitochondrial porin Biochim. Biophys. Acta 1022 1990 311 318 (Pubitemid 20079112)
44. D. Gessmann, and N. Flinner O. Mirus Structural elements of the mitochondrial preprotein-conducting channel Tom40 dissolved by bioinformatics and mass spectrometry Biochim. Biophys. Acta 1807 2011 1647 1657