Airflow limitation, lung volumes and systemic inflammation in a general population

European Respiratory Journal

Volumn 39, Issue 1, 2012, Pages 29-37

  Glaser S ^a   Ittermann, T ^b   Koch, B ^a   Volzke H ^b   Wallaschofski, H ^a   Nauck, M ^a   Warnke, C ^a   Vogelmeier, C ^c   Schulz, H ^d   Felix, S B ^a   Ewert, R ^a   Schaper C ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b Institute for Community Medicine   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

C reactive protein; Diffusing capacity; Inflammation; Lung function; Population based studies

Indexed keywords

C REACTIVE PROTEIN; CARBON MONOXIDE; FIBRINOGEN; HELIUM;

ADULT; AGED; AIRFLOW LIMITATION; ARTICLE; BODY PLETHYSMOGRAPHY; CARDIOPULMONARY FUNCTION; CARDIORESPIRATORY FITNESS; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; FEMALE; FIBRINOGEN BLOOD LEVEL; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; FUNCTIONAL RESIDUAL CAPACITY; HUMAN; INFLAMMATION; LUNG DIFFUSION CAPACITY; LUNG FUNCTION; LUNG VOLUME; MAJOR CLINICAL STUDY; MALE; MAXIMAL EXPIRATORY FLOW; OBESITY; POPULATION RESEARCH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; RESPIRATORY TRACT PARAMETERS; SEX DIFFERENCE; SMOKING; SPIROMETRY; SYSTEMIC INFLAMMATION; TOTAL LUNG CAPACITY;

ADULT; AGED; AGED, 80 AND OVER; C-REACTIVE PROTEIN; CROSS-SECTIONAL STUDIES; DIFFUSION; EXERCISE; FEMALE; HUMANS; INFLAMMATION; LUNG; MALE; MIDDLE AGED; OBESITY; RESPIRATION; SENSITIVITY AND SPECIFICITY; SEX FACTORS; SMOKING;

EID: 84855406596     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00009811     Document Type: Article

References (39)

1. Hancox RJ, Poulton R, Greene JM, et al. Systemic inflammation and lung function in young adults. Thorax 2007; 62: 1064-1068. (Pubitemid 350206198)
2. Rasmussen F, Mikkelsen D, Hancox RJ, et al. High-sensitive C-reactive protein is associated with reduced lung function in young adults. Eur Respir J 2009; 33: 382-388.
3. Thyagarajan B, Jacobs DR, Apostol GG, et al. Plasma fibrinogen and lung function: the CARDIA Study. Int J Epidemiol 2006; 35: 1001-1008. (Pubitemid 44540754)
4. Yende S, Waterer GW, Tolley EA, et al. Inflammatory markers are associated with ventilatory limitation and muscle dysfunction in obstructive lung disease in well functioning elderly subjects. Thorax 2006; 61: 10-16. (Pubitemid 43106971)
5. Tice JA, Browner W, Tracy RP, et al. The relation of C-reactive protein levels to total and cardiovascular mortality in older US females. Am J Med 2003; 114: 199-205. (Pubitemid 36294005)
6. Beaty TH, Cohen BH, Newill CA, et al. Impaired pulmonary function as a risk factor for mortality. Am J Epidemiol 1982; 116: 102-113. (Pubitemid 12087727)
7. Lange P, Nyboe J, Appleyard M, et al. Spirometric findings and mortality in never-smokers. J Clin Epidemiol 1990; 43: 867-873. (Pubitemid 20345964)
8. Thorleifsson SJ, Margretardottir OB, Gudmundsson G, et al. Chronic airflow obstruction and markers of systemic inflammation: results from the BOLD study in Iceland. Respir Med 2009; 103: 1548-1553.
9. Watz H, Waschki B, Kirsten A, et al. The metabolic syndrome in patients with chronic bronchitis and COPD: frequency and associated consequences for systemic inflammation and physical inactivity. Chest 2009; 136: 1039-1046.
10. Volzke H, Alte D, Schmidt CO, et al. Cohort profile: the Study of Health in Pomerania. Int J Epidemiol 2011; 40: 294-307.
11. Spitzer C, Barnow S, Volzke H, et al. Association of posttraumatic stress disorder with low-grade elevation of C-reactive protein: evidence from the general population. J Psychiatr Res 2010; 44: 15-21.
12. World Health Organization. Guidelines for ATC Classification and DDD Assignment. Oslo, WHO Collaborating Centre for Drug Statistics Methodology, 2008.
13. Clauss A. Gerinnungsphysiologische Schnellmethode zur Bestimmung des Fibrinogens [Rapid physiological coagulation method in determination of fibrinogen]. Acta Haematol 1957; 17: 237-246.
14. Nelson SB, Gardner RM, Crapo RO, et al. Performance evaluation of contemporary spirometers. Chest 1990; 97: 288-297. (Pubitemid 20050661)
15. Wanger J, Clausen JL, Coates A, et al. Standardisation of the measurement of lung volumes. Eur Respir J 2005; 26: 511-522. (Pubitemid 41264217)
16. Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J 2005; 26: 319-338. (Pubitemid 41079078)
17. Macintyre N, Crapo RO, Viegi G, et al. Standardisation of the single-breath determination of carbon monoxide uptake in the lung. Eur Respir J 2005; 26: 720-735. (Pubitemid 41448672)
18. Royston P, Sauerbrei W. Multivariable Model-Building: A Pragmatic Approach to Regression Analysis based on Fractional Polynomials for Modelling Continuous Variables. Hoboken, John Wiley & Sons, 2008.
19. Bleumink GS, Knetsch AM, Sturkenboom MC, et al. Quantifying the heart failure epidemic: prevalence, incidence rate, lifetime risk and prognosis of heart failure. The Rotterdam Study. Eur Heart J 2004; 25: 1614-1619. (Pubitemid 39209281)
20. Koch B, Schaper C, Ewert R, et al. Lung function reference values in different German populations. Respir Med 2010; 105: 352-362.
21. Koch B, Schaper C, Ittermann T, et al. Referenzwerte fur die Spirometrie bei Erwachsenen [Reference values for lung function testing in adults - results from the Study of Health in Pomerania (SHIP)]. Dtsch Med Wochenschr 2009; 134: 2327-2332.
22. Pellegrino R, Viegi G, Brusasco V, et al. Interpretative strategies for lung function tests. Eur Respir J 2005; 26: 948-968. (Pubitemid 41632054)
23. Quanjer PH, Tammeling GJ, Cotes JE, et al. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J 1993; 6: Suppl. 16, 5-40.
24. Cotes JE, Chinn DJ, Quanjer PH, et al. Standardization of the measurement of transfer factor (diffusing capacity). Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J 1993; 6: Suppl. 16, 41-52.
25. van Buuren S, Boshuizen HC, Knook DL. Multiple imputation of missing blood pressure covariates in survival analysis. Stat Med 1999; 18: 681-694.
26. Sterne JA, White IR, Carlin JB, et al. Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls. BMJ 2009; 338: b2393.
27. Standardization of spirometry - 1987 update. Official statement of American Thoracic Society. Respir Care 1987; 32: 1039-1060.
28. Aronson D, Avizohar O, Levy Y, et al. Factor analysis of risk variables associated with low-grade inflammation. Atherosclerosis 2008; 200: 206-212.
29. Dehghan A, Dupuis J, Barbalic M, et al. Meta-analysis of genome-wide association studies in >80,000 subjects identifies multiple loci for C-reactive protein levels. Circulation 2011; 123: 731-738.
30. Repapi E, Sayers I, Wain LV, et al. Genome-wide association study identifies five loci associated with lung function. Nat Genet 2010; 42: 36-44.
31. Sattar N, McConnachie A, O'Reilly D, et al. Inverse association between birth weight and C-reactive protein concentrations in the MIDSPAN Family Study. Arterioscler Thromb Vasc Biol 2004; 24: 583-587. (Pubitemid 38326157)
32. Barker DJ, Godfrey KM, Fall C, et al. Relation of birth weight and childhood respiratory infection to adult lung function and death from chronic obstructive airways disease. BMJ 1991; 303: 671-675.
33. Melbye H, Halvorsen DS, Hartz I, et al. Bronchial airflow limitation, smoking, body mass index, and statin use are strongly associated with the C-reactive protein level in the elderly. The Tromso Study 2001. Respir Med 2007; 101: 2541-2549. (Pubitemid 47618385)
34. Koulouris NG, Dimopoulou I, Valta P, et al. Detection of expiratory flow limitation during exercise in COPD patients. J Appl Physiol 1997; 82: 723-731. (Pubitemid 27123247)
35. Hansen JE, Sun XG, Wasserman K. Spirometric criteria for airway obstruction: use percentage of FEV1/FVC ratio below the fifth percentile, not <70%. Chest 2007; 131: 349-355. (Pubitemid 46280391)
36. Vogelmeier C, Buhl R, Criee CP, et al. Leitlinie der Deutschen Atemwegsliga und der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin zur Diagnostik und Therapie von Patienten mit chronisch obstruktiver Bronchitis und Lungenemphysem (COPD) [Guidelines for the diagnosis and therapy of COPD issued by Deutsche Atemwegsliga and Deutsche Gesellschaft fur Pneumologie und Beatmungsmedizin]. Pneumologie 2007; 61: e1-e40.
37. Verbanck S, Schuermans D, Van Muylem A, et al. Conductive and acinar lung-zone contributions to ventilation inhomogeneity in COPD. Am J Respir Crit Care Med 1998; 157: 1573-1577.
38. Rodriguez-Roisin R, Drakulovic M, Rodriguez DA, et al. Ventilation-perfusion imbalance and chronic obstructive pulmonary disease staging severity. J Appl Physiol 2009; 106: 1902-1908.
39. Wang T, Han SX, Zhang SF, et al. Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters. Respir Res 2010; 11: 36.