B cells regulate antibody responses through the medullary remodeling of inflamed lymph nodes

International Immunology

Volumn 24, Issue 1, 2012, Pages 17-27

  Abe, Jun ^a,b   Ueha, Satoshi ^a,b   Yoneyama, Hiroyuki ^c   Shono, Yusuke ^a,d   Kurachi, Makoto ^a,b,e   Goto, Akiteru ^a   Fukayama, Masashi ^a   Tomura, Michio ^a,f   Kakimi, Kazuhiro ^a   Matsushima, Kouji ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c Stelic Institute of Regenerative Medicine   (Japan)

^d HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f KYOTO UNIVERSITY   (Japan)

Author keywords

Lymphotoxin; Non cognate B cell; Plasma cell niche

Indexed keywords

4 NITROPHENOL; ANTIBODY; ANTIGEN; LYMPHOTOXIN BETA RECEPTOR; OVALBUMIN; POLYCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; CELL COUNT; CELL DIVISION; CELL TRANSPORT; CONTROLLED STUDY; HUMORAL IMMUNITY; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; LYMPH NODE; LYMPHADENITIS; MEMBRANE RECONSTITUTION; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STROMA CELL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

EID: 84855398728     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxr089     Document Type: Article

References (43)

1. Willard-Mack, C. L. 2006. Normal structure, function, and histology of lymph nodes. Toxicol. Pathol. 34:409.
2. Cyster, J. G., Ansel, K. M., Reif, K. et al. 2000. Follicular stromal cells and lymphocyte homing to follicles. Immunol. Rev. 176:181.
3. Bajenoff, M., Egen, J. G., Qi, H., Huan, A. Y. C., Castellino, F. and Germain, R. N. 2007. Highways, byways and breadcrumbs: directing lymphocyte traffic in the lymph node. Trend Immunol. 28:346.
4. Mueller, S. N. and Germain, R. N. 2009. Stromal cell contributions to the homeostasis and functionality of the immune system. Nat. Rev. Immunol. 9:618.
5. Bajenoff, M., Egen, J. G., Koo, L. Y. et al. 2006. Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity 25:989.
6. Okada, T. and Cyster, J. G. 2007. CC chemokine receptor 7 contributes to Gi-dependent T cell motility in the lymph node. J. Immunol. 178:2973.
7. Nossal, G. J., Abbot, A. and Mitchell, J. 1968. Antigens in immunity. XIV. Electron microscopic radioautographic studies of antigen capture in the lymph node medulla. J. Exp. Med. 127:263.
8. Iannacone, M., Moseman, E. A., Tonti, E. et al. 2010. Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus. Nature 465:1079.
9. Phan, T. G., Green, J. A., Gray, E. E., Xu, Y. and Cyster, J. G. 2009. Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation. Nat. Immunol. 10:786.
10. Wei, S. H., Rosen, H., Matheu, M. P. et al. 2005. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses. Nat. Immunol. 6:1228.
11. Grigorova, I. L., Schwab, S. R., Phan, T. G., Pham, T. H., Okada, T. and Cyster, J. G. 2009. Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cells. Nat. Immunol. 10:58.
12. Luther, S. A., Gulbranson-Judge, A., Acha-Orbea, H. and MacLennan, I. C. M. 1997. Viral superantigen drives extrafollicular and follicular B cell differentiation leading to virus-specific antibody production. J. Exp. Med. 185:551.
13. Cyster, J. G. 2003. Homing of antibody secreting cells. Immunol. Rev. 194:48.
14. Sanna, P. P. and Burton, D. R. 2000. Role of antibodies in controlling viral disease: lessons from experiments of nature and gene knockouts. J. Virol. 74:9813.
15. Martin, F. and Chan, A. C. 2006. B cell immunobiology in disease: evolving concepts from the clinic. Ann. Rev. Immunol. 24:467.
16. Fooksman, D. R., Schwickert, T. A., Victora, G. D., Dustin, M. L., Nussenzweig, M. C. and Skokos, D. 2010. Development and migration of plasma cells in the mouse lymph node. Immunity 33:118.
17. Mohr, E., Serre, K., Manz, R. A. et al. 2009. Dendritic cells and monocyte/macrophages that create the IL-6/APRIL-rich lymph node microenvironments where plasmablasts mature. J. Immunol. 182:2113.
18. Allen, C. D. C., Okada, T., Tang, H. L. and Cyster, J. G. 2007. Imaging of germinal center selection events during affinity maturation. Science 315:528.
19. Hargreaves, D. C., Hyman, P. L., Lu, T. T. et al. 2001. A coordinated change in chemokine responsiveness guides plasma cell movements. J. Exp. Med. 194:45.
20. Katakai, T., Hara, T., Sugai, M., Gonda, H. and Shimuzu, A. 2004. Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes. J. Exp. Med. 200:783.
21. Allen, C. D. C. and Cyster, J. G. 2008. Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and function. Semin. Immunol. 20:14.
22. Angeli, V., Ginhoux, F., Llodra, J. et al. 2006. B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity 24:203.
23. Webster, B., Ekland, E. H., Agle, L. M., Chyou, S., Ruggieri, R. and Lu, T. T. 2006. Regulation of lymph node vascular growth by dendritic cells. J. Exp. Med. 203:1903.
24. Kumar, V., Scandella, E., Danuser, R. et al. 2010. Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway. Blood 115:4725.
25. Soderberg, K. A., Payne, G. W., Sato, A., Medzhitov, R., Segal, S. S. and Iwasaki, A. 2005. Innate control of adaptive immunity via remodeling of lymph node feed arteriole. Proc. Natl Acad. Sci. USA 102:16315.
26. Liao, S. and Ruddle, N. H. 2006. Synchrony of high endothelial venules and lymphatic vessels revealed by immunization. J. Immunol. 177:3369.
27. Mueller, S. N. and Ahmed, R. 2008. Lymphoid stroma in the initiation and control of immune responses. Immunol. Rev. 224:284.
28. Woodland, R. T., Schmidt, M. R. and Thompson, C. B. 2006. BLyS and B cell homeostasis. Semin. Immunol. 18:318.
29. Kamala, T. 2007. Hock immunization: a humane alternative to mouse footpad injections. J. Immunol. Methods 328:204.
30. Restifo, N. P., Bacik, I., Irvine, K. R. et al. 1995. Antigen processing in vivo and the elicitation of primary CTL responses. J. Immunol. 154:4414.
31. Yoneyama, H., Matsuno, K., Toda, E. et al. 2005. Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs. J. Exp. Med. 202:425.
32. Pope, C., Kim, S. K., Marzo, A. et al. 2001. Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection. J. Immunol. 166:3402.
33. Mackay, F., Schneider, P., Rennert, P. and Browning, J. 2003. BAFF and APRIL: a tutorial on B cell survival. Ann. Rev. Immunol. 21:231.
34. Serbina, N. V. and Pamer, E. G. 2006. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat. Immunol. 7:311.
35. Browning, J. L. 2008. Inhibition of the lymphotoxin pathway as a therapy for autoimmune disease. Immunol. Rev. 223:202.
36. Randall, T. D., Carragher, D. M. and Rangel-Moreno, J. 2008. Development of secondary lymphoid organs. Annu. Rev. Immunol. 26:627.
37. Browning, J. L., Allaire, N., Ngam-Ek, A. et al. 2005. Lymphotoxinb receptor signaling is required for the homeostatic control of HEV differentiation and function. Immunity 23:539.
38. Katakai, T., Suto, H., Sugai, M. et al. 2008. Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs. J. Immunol. 181:6189.
39. FH) cells in normal and dysregulated immune responses. Ann. Rev. Immunol. 26:741.
40. Kataru, R. P., Kim, H., Jang, C. et al. 2011. T lymphocytes negatively regulate lymph node lymphatic vessel formation. Immunity 34:96.
41. Junt, T., Tumanov, A. V., Harris, N. et al. 2006. Expression of lymphotoxin b governs immunity at two distinct levels. Eur. J. Immunol. 36:2061.
42. Wang, H., Feng, J., Qi, C. and Morse, H. C. III 2008. An ENUinduced mutation in the lymphotoxin a gene impairs organogenesis of lymphoid tissues in C57BL/6 mice. Biochem. Biophys. Res. Commun. 370:461.
43. Ansel, K. M., Ngo, V. N., Hyman, P. L. et al. 2000. A chemokinedriven positive feedback loop organizes lymphoid follicles. Nature Vasanth89. 406:309.