메뉴 건너뛰기




Volumn 8, Issue 4, 2011, Pages 254-257

Novel pharmacological strategies to prevent aortic complications in Marfan syndrome

Author keywords

Aneurysm; Angiotensin receptor blocker; Marfan syndrome

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CANDESARTAN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOXYCYCLINE; FIBRILLIN 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IRBESARTAN; LOSARTAN; PRAVASTATIN; PROPRANOLOL; TRANSFORMING GROWTH FACTOR BETA;

EID: 84855394897     PISSN: 16715411     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1263.2011.00254     Document Type: Review
Times cited : (4)

References (31)
  • 1
    • 64649093359 scopus 로고    scopus 로고
    • Valve-sparing and valve-replacing techniques for aortic root replacement in patients with Marfan syndrome: Analysis of early outcome
    • Volguina IV, Miller DC, LeMaire SA, et al. Valve-sparing and valve-replacing techniques for aortic root replacement in patients with Marfan syndrome: Analysis of early outcome. J Thorac Cardiovasc Surg 2009; 137: 1124-1132.
    • (2009) J Thorac Cardiovasc Surg , vol.137 , pp. 1124-1132
    • Volguina, I.V.1    Miller, D.C.2    LeMaire, S.A.3
  • 2
    • 64649096750 scopus 로고    scopus 로고
    • Aortic root replacement in 372 Marfan patients: Evolution of operative repair over 30 years
    • discussion 1349-1350
    • Cameron DE, Alejo DE, Patel ND, et al. Aortic root replacement in 372 Marfan patients: evolution of operative repair over 30 years. Ann Thorac Surg 2009; 87: 1344-1349; discussion 1349-1350.
    • (2009) Ann Thorac Surg , vol.87 , pp. 1344-1349
    • Cameron, D.E.1    Alejo, D.E.2    Patel, N.D.3
  • 5
    • 77956127537 scopus 로고    scopus 로고
    • The revised Ghent nosology for the Marfan syndrome
    • Loeys BL, Dietz HC, Braverman AC, et al. The revised Ghent nosology for the Marfan syndrome. J Med Genet 2010; 47: 476-485.
    • (2010) J Med Genet , vol.47 , pp. 476-485
    • Loeys, B.L.1    Dietz, H.C.2    Braverman, A.C.3
  • 6
    • 76649100088 scopus 로고    scopus 로고
    • TGF-beta in the pathogenesis and prevention of disease: A matter of aneurysmic proportions
    • Dietz HC. TGF-beta in the pathogenesis and prevention of disease: a matter of aneurysmic proportions. J Clin Invest 2010; 120: 403-407.
    • (2010) J Clin Invest , vol.120 , pp. 403-407
    • Dietz, H.C.1
  • 9
    • 33645672459 scopus 로고    scopus 로고
    • Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome
    • Habashi JP, Judge DP, Holm TM, et al. Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. Science 2006; 312: 117-121.
    • (2006) Science , vol.312 , pp. 117-121
    • Habashi, J.P.1    Judge, D.P.2    Holm, T.M.3
  • 10
    • 33846946114 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states
    • Cohn RD, van Erp C, Habashi JP, et al. Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states. Nat Med 2007; 13: 204-210.
    • (2007) Nat Med , vol.13 , pp. 204-210
    • Cohn, R.D.1    Van Erp, C.2    Habashi, J.P.3
  • 11
    • 0028296142 scopus 로고
    • Progression of aortic dilatation and the benefit of long-term beta-adrenergic blockade in Marfan's syndrome
    • Shores J, Berger KR, Murphy EA, et al. Progression of aortic dilatation and the benefit of long-term beta-adrenergic blockade in Marfan's syndrome. N Engl J Med 1994; 330: 1335-1341.
    • (1994) N Engl J Med , vol.330 , pp. 1335-1341
    • Shores, J.1    Berger, K.R.2    Murphy, E.A.3
  • 12
    • 0027939984 scopus 로고
    • Effect of beta-adrenergic blockade on aortic root rate of dilation in the Marfan syndrome
    • DOI 10.1016/0002-9149(94)90762-5
    • Salim MA, Alpert BS, Ward JC, et al. Effect of beta-adrenergic blockade on aortic root rate of dilation in the Marfan syndrome. Am J Cardiol 1994; 74: 629-633. (Pubitemid 24279954)
    • (1994) American Journal of Cardiology , vol.74 , Issue.6 , pp. 629-633
    • Salim, M.A.1    Alpert, B.S.2    Ward, J.C.3    Pyeritz, R.E.4
  • 13
    • 34249688228 scopus 로고    scopus 로고
    • Marfan syndrome: from molecular pathogenesis to clinical treatment
    • DOI 10.1016/j.gde.2007.04.006, PII S0959437X07000718
    • Ramirez F, Dietz HC. Marfan syndrome: from molecular pathogenesis to clinical treatment. Curr Opin Genet Dev 2007; 17: 252-258. (Pubitemid 46843550)
    • (2007) Current Opinion in Genetics and Development , vol.17 , Issue.3 , pp. 252-258
    • Ramirez, F.1    Dietz, H.C.2
  • 14
    • 20444441924 scopus 로고    scopus 로고
    • Therapy insight: Aortic aneurysm and dissection in Marfan's syndrome
    • DOI 10.1038/ncpcardio0020
    • Ramirez F, Dietz HC. Therapy insight: aortic aneurysm and dissection in Marfan's syndrome. Nat Clin Pract Cardiovasc Med 2004; 1: 31-36. (Pubitemid 40823719)
    • (2004) Nature Clinical Practice Cardiovascular Medicine , vol.1 , Issue.1 , pp. 31-36
    • Ramirez, F.1    Dietz, H.C.2
  • 17
    • 84855385948 scopus 로고    scopus 로고
    • Angiotensin II blockade and beta-blockade combination therapy slows down the aortic root dilatation in patients with Marfan syndrome
    • Chiu HH, Wu MH, Wang JJ, et al. Angiotensin II blockade and beta-blockade combination therapy slows down the aortic root dilatation in patients with Marfan syndrome. Circulation 2010; 122: A2134.
    • (2010) Circulation , vol.122
    • Chiu, H.H.1    Wu, M.H.2    Wang, J.J.3
  • 18
    • 78650703447 scopus 로고    scopus 로고
    • Antihypertensive drugs and risk of cancer: Network meta-analyses and trial sequential analyses of 324,168 participants from randomised trials
    • Bangalore S, Kumar S, Kjeldsen SE, et al. Antihypertensive drugs and risk of cancer: network meta-analyses and trial sequential analyses of 324,168 participants from randomised trials. Lancet Oncol 2011; 12: 65-82.
    • (2011) Lancet Oncol , vol.12 , pp. 65-82
    • Bangalore, S.1    Kumar, S.2    Kjeldsen, S.E.3
  • 19
    • 54049140029 scopus 로고    scopus 로고
    • Angiotensin II blockade in Marfan's syndrome
    • author reply 1733-1734
    • Ahimastos AA, Dart AM, Kingwell BA. Angiotensin II blockade in Marfan's syndrome. N Engl J Med 2008; 359: 1732; author reply 1733-1734.
    • (2008) N Engl J Med , vol.359 , pp. 1732
    • Ahimastos, A.A.1    Dart, A.M.2    Kingwell, B.A.3
  • 21
    • 79954579275 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism
    • Habashi JP, Doyle JJ, Holm TM, et al. Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism. Science 2011; 332: 361-365.
    • (2011) Science , vol.332 , pp. 361-365
    • Habashi, J.P.1    Doyle, J.J.2    Holm, T.M.3
  • 22
    • 37549052556 scopus 로고    scopus 로고
    • Doxycycline delays aneurysm rupture in a mouse model of Marfan syndrome
    • discussion 172
    • Xiong W, Knispel RA, Dietz HC, et al. Doxycycline delays aneurysm rupture in a mouse model of Marfan syndrome. J Vasc Surg 2008; 47: 166-172; discussion 172.
    • (2008) J Vasc Surg , vol.47 , pp. 166-172
    • Xiong, W.1    Knispel, R.A.2    Dietz, H.C.3
  • 23
    • 34548437703 scopus 로고    scopus 로고
    • Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome
    • DOI 10.1161/CIRCRESAHA.107.157776
    • Chung AW, Au Yeung K, Sandor GG, et al. Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome. Circ Res 2007; 101: 512-522. (Pubitemid 47351231)
    • (2007) Circulation Research , vol.101 , Issue.5 , pp. 512-522
    • Chung, A.W.Y.1    Au, Y.K.2    Sandor, G.G.S.3    Judge, D.P.4    Dietz, H.C.5    Van Breemen, C.6
  • 24
    • 33745947969 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2 activation of Transforming Growth Factor-beta1 (TGF-beta1) and TGF-beta1-type II receptor signaling within the aged arterial wall
    • DOI 10.1161/01.ATV.0000225777.58488.f2, PII 0004360520060700000015
    • Wang M, Zhao D, Spinetti G, et al. Matrix metalloproteinase 2 activation of transforming growth factor-beta1 (TGF-beta1) and TGF-beta1-type II receptor signaling within the aged arterial wall. Arterioscler Thromb Vasc Biol 2006; 26: 1503-1509. (Pubitemid 44288975)
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , Issue.7 , pp. 1503-1509
    • Wang, M.1    Zhao, D.2    Spinetti, G.3    Zhang, J.4    Jiang, L.-Q.5    Pintus, G.6    Monticone, R.7    Lakatta, E.G.8
  • 25
    • 77955473542 scopus 로고    scopus 로고
    • Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome
    • Yang HH, Kim JM, Chum E, et al. Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome. J Thorac Cardiovasc Surg 2010; 140: 305-312.
    • (2010) J Thorac Cardiovasc Surg , vol.140 , pp. 305-312
    • Yang, H.H.1    Kim, J.M.2    Chum, E.3
  • 26
    • 61349174801 scopus 로고    scopus 로고
    • Pravastatin prevents aortic root dilation in Marfan Syndrome
    • Byrne JS, McGuinnes J, Tobin E, et al. Pravastatin prevents aortic root dilation in Marfan Syndrome. Circulation 2008; 118: S857.
    • (2008) Circulation , vol.118
    • Byrne, J.S.1    McGuinnes, J.2    Tobin, E.3
  • 27
    • 79954625123 scopus 로고    scopus 로고
    • Noncanonical TGF beta signaling contributes to aortic aneurysm progression in Marfan syndrome mice
    • Holm TM, Habashi JP, Doyle JJ, et al. Noncanonical TGF beta signaling contributes to aortic aneurysm progression in Marfan syndrome mice. Science 2011; 332: 358-361.
    • (2011) Science , vol.332 , pp. 358-361
    • Holm, T.M.1    Habashi, J.P.2    Doyle, J.J.3
  • 28
    • 69449090360 scopus 로고    scopus 로고
    • Circulating transforming growth factor-beta in Marfan syndrome
    • Matt P, Schoenhoff F, Habashi J, et al. Circulating transforming growth factor-beta in Marfan syndrome. Circulation 2009; 120: 526-532.
    • (2009) Circulation , vol.120 , pp. 526-532
    • Matt, P.1    Schoenhoff, F.2    Habashi, J.3
  • 29
    • 66849131058 scopus 로고    scopus 로고
    • Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway
    • Gomez D, Al Haj Zen A, Borges LF, et al. Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway. J Pathol 2009; 218: 131-142.
    • (2009) J Pathol , vol.218 , pp. 131-142
    • Gomez, D.1    Al Haj Zen, A.2    Borges, L.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.